3,016 Matching Annotations
  1. Sep 2022
  2. aacrjournals.org aacrjournals.org
    Orthovoltage X-Rays Exhibit Increased Efficacy Compared with γ-Rays in Preclinical Irradiation
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    aacrjournals.org/cancerres/article/82/15/2678/707330/Orthovoltage-X-Rays-Exhibit-Increased-Efficacy
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    Ensembles of endothelial and mural cells promote angiogenesis in prenatal human brain
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    sciencedirect.com/science/article/pii/S0092867422011266
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    Mucus-degrading Bacteroides link carbapenems to aggravated graft-versus-host disease
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    sciencedirect.com/science/article/pii/S0092867422011291
  5. www.embopress.org www.embopress.org
    Dipeptidyl peptidase 9 triggers BRCA2 degradation and promotes DNA damage repair
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    embopress.org/doi/10.15252/embr.202154136
  6. www.nature.com www.nature.com
    Genetically modified CD7-targeting allogeneic CAR-T cell therapy with enhanced efficacy for relapsed/refractory CD7-positive hematological malignancies: a phase I clinical study
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    nature.com/articles/s41422-022-00721-y
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined – whole blood and skin fibroblasts- transcriptomic analysis in Psoriatic Arthritis reveals molecular signatures of activity, resistance and early response to treatment
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    ncbi.nlm.nih.gov/pmc/articles/PMC9493103/
  8. www.nature.com www.nature.com
    BCGΔBCG1419c increased memory CD8+ T cell-associated immunogenicity and mitigated pulmonary inflammation compared with BCG in a model of chronic tuberculosis
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    nature.com/articles/s41598-022-20017-w
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-viral efficacy of a next-generation CD4-binding site bNAb in SHIV-infected animals in the absence of anti-drug antibody responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC9490026/
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    Human anti-smallpox long-lived memory B cells are defined by dynamic interactions in the splenic niche and long-lasting germinal center imprinting
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    sciencedirect.com/science/article/pii/S1074761322004137
  11. journals.biologists.com journals.biologists.com
    Dhx38 regulates the maintenance and differentiation of erythro-myeloid progenitors and hematopoietic stem cells by alternative splicing
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    journals.biologists.com/dev/article/149/17/dev200450/276469/Dhx38-is-required-for-the-maintenance-and
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytomegalovirus-specific neutralizing antibodies effectively prevent uncontrolled infection after allogeneic hematopoietic stem cell transplantation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9485910/
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    Pangenomic analysis of Chinese gastric cancer
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    nature.com/articles/s41467-022-33073-7
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    Sex differences in brain tumor glutamine metabolism reveal sex-specific vulnerabilities to treatment
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    sciencedirect.com/science/article/pii/S2666634022003658
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    Metronomic cyclophosphamide is more effective than a single dose in resistant tumours Cyclophosphamide depletes tumour infiltrating T regulatory cells and combined with anti-PD-1 therapy improves survival in murine neuroblastoma
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    sciencedirect.com/science/article/pii/S2589004222012676
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Defining the Immune Checkpoint Landscape in Human Colorectal Cancer Highlights the Relevance of the TIGIT/CD155 Axis for Optimizing Immunotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC9454990/
  17. www.sciencedirect.com www.sciencedirect.com
    Human gut microbiota stimulate defined innate immune responses that vary from phylum to strain
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    sciencedirect.com/science/article/pii/S1931312822004085
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myeloid Wls expression is dispensable for skin wound healing and blood vessel regeneration
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    ncbi.nlm.nih.gov/pmc/articles/PMC9446346/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dendritic cell Piezo1 directs the differentiation of TH1 and Treg cells in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9451538/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic remodeling by vitamin C potentiates plasma cell differentiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9451539/
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    Ablating Lgr5-expressing prostatic stromal cells activates the ERK-mediated mechanosensory signaling and disrupts prostate tissue homeostasis
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    sciencedirect.com/science/article/pii/S2211124722011378
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    Landscape and age dynamics of immune cells in the Egyptian rousette bat
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    sciencedirect.com/science/article/pii/S2211124722011299
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reversible epigenetic alterations regulate class I HLA loss in prostate cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437063/
  24. www.sciencedirect.com www.sciencedirect.com
    Sublethal cytochrome c release generates drug-tolerant persister cells
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    sciencedirect.com/science/article/pii/S0092867422009783
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of beta-catenin dependent Wnt signaling in colon cancer cells remodels the microenvironment to promote tumor invasion
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    ncbi.nlm.nih.gov/pmc/articles/PMC8898281/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrative RNA-omics discovers GNAS alternative splicing as a phenotypic driver of splicing factor-mutant neoplasms
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    ncbi.nlm.nih.gov/pmc/articles/PMC8904276/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intracellular cholesterol pools regulate oncogenic signaling and epigenetic circuitries in Early T-cell Precursor Acute Lymphoblastic Leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8904296/
  28. aacrjournals.org aacrjournals.org
    Na+/H+-exchanger 1 Enhances Antitumor Activity of Engineered NK-92 Natural Killer Cells
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    aacrjournals.org/cancerrescommun/article/2/8/842/708157/Na-H-exchanger-1-Enhances-Antitumor-Activity-of
  29. Aug 2022
  30. www.sciencedirect.com www.sciencedirect.com
    Protocol for assessing translational regulation in mammalian cell lines by OP-Puro labeling
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    sciencedirect.com/science/article/pii/S2666166722005342
  31. www.sciencedirect.com www.sciencedirect.com
    SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression
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    sciencedirect.com/science/article/pii/S2211124722011081
  32. www.sciencedirect.com www.sciencedirect.com
    Enterobacter ludwigii protects DSS-induced colitis through choline-mediated immune tolerance
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    sciencedirect.com/science/article/pii/S2211124722011329
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    Distinct silencer states generate epigenetic states of heterochromatin
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    sciencedirect.com/science/article/pii/S1097276522007559
  34. www.sciencedirect.com www.sciencedirect.com
    Protocol for isolation and characterization of lung tissue resident memory T cells and airway trained innate immunity after intranasal vaccination in mice
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    sciencedirect.com/science/article/pii/S2666166722005329
  35. 52.53.155.43 52.53.155.43
    can-22-0631-html.html
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  36. www.sciencedirect.com www.sciencedirect.com
    Lymphatic migration of unconventional T cells promotes site-specific immunity in distinct lymph nodes
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    sciencedirect.com/science/article/pii/S1074761322003545
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting ribonucleotide reductase induces synthetic lethality in PP2A-deficient uterine serous carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC8857033/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immunodeficiency syndromes differentially impact the functional spectrum of SARS-CoV-2-specific T cells elicited by mRNA vaccination
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    ncbi.nlm.nih.gov/pmc/articles/PMC9293955/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CXCR4high megakaryocytes regulate host-defense immunity against bacterial pathogens
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    ncbi.nlm.nih.gov/pmc/articles/PMC9374440/
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    Increasing cell size remodels the proteome and promotes senescence
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    sciencedirect.com/science/article/pii/S1097276522007134
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    Dysbiosis in imiquimod-induced psoriasis alters gut immunity and exacerbates colitis development
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    sciencedirect.com/science/article/pii/S2211124722010087
  42. aacrjournals.org aacrjournals.org
    Proteomic mapping and targeting of mitotic pericentriolar material in tumors bearing centrosome amplification
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    aacrjournals.org/cancerres/article/82/14/2576/706950/Proteomic-Mapping-and-Targeting-of-Mitotic
  43. www.sciencedirect.com www.sciencedirect.com
    Allelic polymorphism controls autoreactivity and vaccine elicitation of human broadly neutralizing antibodies against influenza virus
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    sciencedirect.com/science/article/pii/S1074761322003399
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    Infection order outweighs the role of CD4+ T cells in tertiary flavivirus exposure
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    sciencedirect.com/science/article/pii/S2589004222010367
  45. www.sciencedirect.com www.sciencedirect.com
    Identification of a drug-response gene in multiple myeloma through longitudinal single-cell transcriptome sequencing
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    sciencedirect.com/science/article/pii/S2589004222010537
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitotane Targets Lipid Droplets to Induce Lipolysis in Adrenocortical Carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9342684/
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    Rapid GPR183-mediated recruitment of eosinophils to the lung after Mycobacterium tuberculosis infection
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    sciencedirect.com/science/article/pii/S2211124722009536
  48. Jul 2022
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive fitness landscape of SARS-CoV-2 Mpro reveals insights into viral resistance mechanisms
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    ncbi.nlm.nih.gov/pmc/articles/PMC9323007/
  50. 52.53.155.43 52.53.155.43
    can-21-4313-html.html
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    52.53.155.43/cccf0ba471fe636f8ee073caf3b8f7a0d9b2bd8e/can-21-4313-html.html
  51. 52.53.155.43 52.53.155.43
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    52.53.155.43/10b1307b786c1d01a6cf28f8a0210c58728fe8fb/can-21-3713-html.html
  52. www.nature.com www.nature.com
    Mitotic SENP3 activation couples with cGAS signaling in tumor cells to stimulate anti-tumor immunity
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    nature.com/articles/s41419-022-05063-6
  53. link.springer.com link.springer.com
    Targeting lactate dehydrogenase B-dependent mitochondrial metabolism affects tumor initiating cells and inhibits tumorigenesis of non-small cell lung cancer by inducing mtDNA damage
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    link.springer.com/article/10.1007/s00018-022-04453-5
  54. www.sciencedirect.com www.sciencedirect.com
    Phloretin enhances autophagy by impairing AKT activation and inducing JNK-Beclin-1 pathway activation
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    sciencedirect.com/science/article/pii/S0014480022000776
  55. www.sciencedirect.com www.sciencedirect.com
    Oncogenic collagen I homotrimers from cancer cells bind to α3β1 integrin and impact tumor microbiome and immunity to promote pancreatic cancer
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    sciencedirect.com/science/article/pii/S1535610822002756
  56. www.medrxiv.org www.medrxiv.org
    http://medrxiv.org/cgi/content/short/2020.08.10.20171371
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    medrxiv.org/content/10.1101/2020.08.10.20171371v1
  57. www.frontiersin.org www.frontiersin.org
    Impaired Cellular Immunity to SARS-CoV-2 in Severe COVID-19 Patients
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    frontiersin.org/articles/10.3389/fimmu.2021.603563/full
  58. www.sciencedirect.com www.sciencedirect.com
    Irradiation combined with PD-L1-/- and autophagy inhibition enhances the antitumor effect of lung cancer via cGAS-STING mediated T cell activation
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    sciencedirect.com/science/article/pii/S2589004222009622
  59. www.sciencedirect.com www.sciencedirect.com
    Multiomics reveal the central role of pentose phosphate pathway in resident thymic macrophages to cope with efferocytosis-associated stress
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    sciencedirect.com/science/article/pii/S2211124722008634
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    HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs
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    sciencedirect.com/science/article/pii/S2211124722008324
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    T-cell dysfunction upon expression of MYC with altered phosphorylation at Threonine 58 and Serine 62
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    ncbi.nlm.nih.gov/pmc/articles/PMC9262837/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Babesia microti Infection Inhibits Melanoma Growth by Activating Macrophages in Mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC9257138/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differentiated glioma cell-derived fibromodulin activates integrin-dependent Notch signaling in endothelial cells to promote tumor angiogenesis and growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC9259034/
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    Extracellular vesicles from thyroid cancer harbor a functional machinery involved in extracellular matrix remodeling
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    sciencedirect.com/science/article/pii/S0171933522000577
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    Epiblast inducers capture mouse trophectoderm stem cells in vitro and pattern blastoids for implantation in utero
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    sciencedirect.com/science/article/pii/S193459092200251X
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    Tissue-resident memory and circulating T cells are early responders to pre-surgical cancer immunotherapy
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    sciencedirect.com/science/article/pii/S0092867422007231
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant chemotherapy induces genomic and transcriptomic changes in ovarian cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8936832/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CD47-SIRPα Controls ADCC Killing of Primary T Cells by PMN Through a Combination of Trogocytosis and NADPH Oxidase Activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9252436/
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    An automated do-it-yourself system for dynamic stem cell and organoid culture in standard multi-well plates
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    sciencedirect.com/science/article/pii/S2667237522001138
  70. Jun 2022
  71. 52.53.155.43 52.53.155.43
    cd-21-1514-html.html
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  72. 52.53.155.43 52.53.155.43
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    52.53.155.43/dae3a722cb0f412060233d3b16799226aa47507e/cd-21-1022-html.html
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Domain fusion TLR2-4 enhances the autophagy-dependent clearance of Staphylococcus aureus in the genetic engineering goat
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    ncbi.nlm.nih.gov/pmc/articles/PMC9239677/
  74. 52.53.155.43 52.53.155.43
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    BAFFR activates PI3K/AKT signaling in human naive but not in switched memory B cells through direct interactions with B cell antigen receptors
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    sciencedirect.com/science/article/pii/S2211124722008087
  76. www.embopress.org www.embopress.org
    Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells
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    embopress.org/doi/10.15252/embr.202154133
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    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    sciencedirect.com/science/article/pii/S109727652200541X
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    The cephalic phase of insulin release is modulated by IL-1β
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    sciencedirect.com/science/article/pii/S1550413122002212
  79. 52.53.155.43 52.53.155.43
    Glypican-3 targeted thorium-227 alpha therapy reduces tumor burden in an orthotopic xenograft murine model of hepatocellular carcinoma
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    52.53.155.43/e74a10bf6779c4758159865813a971393052d487/jnumed.121.262562.full-html.html
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ROS Inhibits Cell Growth by Regulating 4EBP and S6K, Independent of TOR, during Development
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    ncbi.nlm.nih.gov/pmc/articles/PMC7612857/
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neoadjuvant FOLFIRINOX therapy is associated with increased effector T cells and reduced suppressor cells in pancreatic cancer patients
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    ncbi.nlm.nih.gov/pmc/articles/PMC8678309/
  82. elifesciences.org elifesciences.org
    GSK3 inhibition rescues growth and telomere dysfunction in dyskeratosis congenita iPSC-derived type II alveolar epithelial cells
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    elifesciences.org/articles/64430
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Simple and Robust Single-Step Method for CAR-Vδ1 γδT Cell Expansion and Transduction for Cancer Immunotherapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC9197253/
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    Neuropilin-1 cooperates with PD-1 in CD8+ T-cells predicting outcomes in melanoma patients treated with anti-PD1
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    sciencedirect.com/science/article/pii/S2589004222006241
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    Development of an HIV reporter virus that identifies latently infected CD4+ T cells
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    sciencedirect.com/science/article/pii/S2667237522001072
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive surfaceome profiling to identify and validate novel cell-surface targets in osteosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9167717/
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    Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice
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    sciencedirect.com/science/article/pii/S2211124722007434
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    Poroptosis: a form of cell death depending on plasma membrane nanopores formation
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    sciencedirect.com/science/article/pii/S2589004222007520
  89. aacrjournals.org aacrjournals.org
    Phosphorylation and stabilization of PD-L1 by CK2 suppresses dendritic cell function
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    aacrjournals.org/cancerres/article/82/11/2185/699105/Phosphorylation-and-Stabilization-of-PD-L1-by-CK2
  90. aacrjournals.org aacrjournals.org
    Porcupine inhibition disrupts mitochondrial function and homeostasis in WNT ligand-addicted pancreatic cancer
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  127. Apr 2022
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    MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding
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    aacrjournals.org/cancerrescommun/article/2/2/110/681605/MYC-Inhibition-Halts-Metastatic-Breast-Cancer
  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytidine Deaminase APOBEC3A Regulates PD-L1 Expression in Cancer Cells in a JNK/c-JUN-dependent Manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC8419025/
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nonsense-mediated RNA decay is a unique vulnerability of cancer cells harboring SF3B1 or U2AF1 mutations
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    ncbi.nlm.nih.gov/pmc/articles/PMC8416940/
  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating Mucosal-Associated Invariant T cells Induces a Broad Antitumor Response
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  182. www.sciencedirect.com www.sciencedirect.com
    Immunodepletion of MDSC by AMV564, a novel bivalent, bispecific CD33/CD3 T cell engager, ex vivo in MDS and melanoma
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms
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    ncbi.nlm.nih.gov/pmc/articles/PMC8871394/
  184. www.sciencedirect.com www.sciencedirect.com
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2
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    ncbi.nlm.nih.gov/pmc/articles/PMC8825346/
  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nicotinamide Breaks Effector CD8 T cell Responses by Targeting mTOR Signaling
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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Conditioning Lesion Response in Dorsal Root Ganglion Neurons Is Inhibited in Oncomodulin Knock-Out Mice
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  189. www.sciencedirect.com www.sciencedirect.com
    Structure-guided changes at the V2 apex of HIV-1 clade C trimer enhance elicitation of autologous neutralizing and broad V1V2-scaffold antibodies
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  190. www.sciencedirect.com www.sciencedirect.com
    Follicular T Cells Optimize the Germinal Center Response to SARS-CoV-2 Protein Vaccination in Mice
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  191. Feb 2022
  192. www.sciencedirect.com www.sciencedirect.com
    Protocol to identify and monitor key mutations of broadly neutralizing antibody lineages following sequential immunization of Ig-humanized mice
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  193. www.sciencedirect.com www.sciencedirect.com
    EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells
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  194. elifesciences.org elifesciences.org
    Recapitulating human cardio-pulmonary co-development using simultaneous multilineage differentiation of pluripotent stem cells
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    elifesciences.org/articles/67872
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity
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  196. elifesciences.org elifesciences.org
    Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes
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  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target
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  198. www.sciencedirect.com www.sciencedirect.com
    Aire suppresses CTLA-4 expression from the thymic stroma to control autoimmunity
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  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sesquiterpene Lactones Potentiate Olaparib-Induced DNA Damage in p53 Wildtype Cancer Cells
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    The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria
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    Substrate rigidity dictates colorectal tumorigenic cell stemness and metastasis via CRAD-dependent mechanotransduction
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  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A zebrafish embryo screen utilizing gastrulation identifies the HTR2C inhibitor pizotifen as a suppressor of EMT-mediated metastasis
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  203. insight.jci.org insight.jci.org
    Mosaic loss of chromosome Y promotes leukemogenesis and clonal hematopoiesis
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