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  1. Feb 2023
  2. www.science.org www.science.org
    MicroRNA-mediated inhibition of transgene expression reduces dorsal root ganglion toxicity by AAV vectors in primates
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    1. thwilli2 05 Feb 2023
      Although these vectors were safe, many gene therapy programs failed in the clinic because of poor transduction.

      i.e., these were not good expression vectors because they did not effectively transfer transgenetic material to the host.

      #expression vector
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    science.org/doi/10.1126/scitranslmed.aba9188