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    1. bacarter 23 Jul 2024
      that very low (nM) concentrations of GABA,which typically occur in the cerebrospinal fluid (CSF) of the extracellular space,can persistently activate a population of non-synaptic GABA A receptors resultingin a ‘tonic’ increase in membrane conductance

      GABA typically occurs in the CSF, and very small levels of GABA can activate extrasynaptic receptors.

      Tonic Inhibition Ambient GABA Extrasynaptic

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