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Leukaemogenic effects of Ptpn11 activating mutations in the stem cell microenvironment

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1. shafiqul.bhuiya 12 Jun 2026
  
  in Public
  
  Figure 1. Ptpn11E76K/+ mutation in Nestin+ MSPCs aberrantly activates neighbouring wild-type HSCs, inducing MPN in Ptpn11E76K/+Nestin-Cre+ mice.
  
  OS2
  
  Gene:PTPN11 Disease:MPN PMID:27783593
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Disease:MPN

PMID:27783593

Gene:PTPN11

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shafiqul.bhuiya

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pmc.ncbi.nlm.nih.gov/articles/PMC5317374/