13 Matching Annotations
  1. Jul 2015
  2. Jun 2015
    1. The active transcription factor bound to the consensus sequence was incubated with a specific primary antibody (NF-κB p65) a

      Interesting that with the problems reported with NK-kB antibodies, the exact primary antibody is not mentioned here.

      Would like to be able to easily look up an article from Pub Med or Google Scholar and insert the link, as I did below.

    2. mouse SphK1

      Would like to be able to perform a lookup from the Antibody Registry to see whether this antibody has an RRID. In this case, although not enough information was provided, it is likely that this antibody is: RRID:AB_2271047, as it is the only mouse antibody in Santa Cruz' catalog against this protein. But that is really insufficient information. So perhaps we would we able to open up a channel with the author to ask them to provide more information.

      Would like to be able to automatically insert the link and some language around it, if an RRID is available. See annotation below.

    3. resveratrol

      Or could embed the NIF navigator within H:

      NIF has the following type of information available about Resveratrol:

      • Annotation(45,733)
      • Brain Activation Foci(552)
      • Clinical Trials(190)
      • Dataset(114)
      • Disease(1,243,446)
      • Drugs(637,343)
      • Expression(200,724)
      • Grants(444)
      • Images(31)
      • Microarray(200,765)
      • Multimedia(37)
      • Phenotype(8)
    4. Taken together, this study provides novel insights into the modes of action of RSV by establishing its strong inhibitory effect on SphK1 and PLD activities, as well as ERK1/2 phosphorylation.

      I'm not an expert, so I am taking them at their word. The interesting this is how CTD took the results of this paper and inferred that there was a link between a drug and a disease. It involves a chain of reasoning that says, as best as I can tell in this short exercise: This study shows an effect RSV on pathways involved in C5-induced inflammation, a mouse model of acute peritonitis. Various drugs interact with C5, therefore they are inferred to have an effect on peritonitis. I have to do some more digging, but this will be a challenge to model in an annotation.