On 2014 Apr 24, Milad Nazarzadeh commented:

Tramadol hydrochloride is a common prescription pain reliever that is structurally similar to morphine and codeine with its analgesic effects identified as a mu-receptor agonist. Due to its opioid-like stimulant effects, the potential for tramadol misuse is a public health concern. According to our latest research finding, tramadol could be a related factor or co-factor for adolescent alcohol, cannabis and ecstasy abuse. This issue should be considered in tramadol prescription for treatment of premature ejaculation.

On 2014 Apr 24, Milad Nazarzadeh commented:

Tramadol hydrochloride is a common prescription pain reliever that is structurally similar to morphine and codeine with its analgesic effects identified as a mu-receptor agonist. Due to its opioid-like stimulant effects, the potential for tramadol misuse is a public health concern. According to our latest research finding, tramadol could be a related factor or co-factor for adolescent alcohol, cannabis and ecstasy abuse. This issue should be considered in tramadol prescription for treatment of premature ejaculation.