On 2013 Oct 23, Hilda Bastian commented:

This paper by Jager and Leek (Jager LR, 2014) challenges Ioannidis' conclusion that "most published research papers are false" (Ioannidis JP, 2005). Ioannidis responds to this discussion, challenging the data and analytical approach here: (Ioannidis JP, 2014). The conclusions of this paper (Ioannidis JP, 2005) were also challenged by Goodman and Greenfield in 2007 (and responded to by Ioannidis JP, 2007). (I discuss this debate in a blog post.)

On 2013 Oct 23, Larry Wasserman commented:

I agree with Rob that this is an interesting paper. However, it does assume that the p-values are uniform under the null. Hidden biases can compromise this assumption leading to a distribution for the p-value that is skewed towards 0.

On 2013 Oct 22, Scott D McGinnis commented:

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On 2013 Oct 22, Robert Tibshirani commented:

A really interesting paper and discussion, that calls into question Ioannidis' 2007 widely cited paper "Why Most Published Research Findings Are False". Definitely worth reading: includes a discussion by D.R. Cox, probably the world's most famous living statistician.

On 2013 Oct 22, Robert Tibshirani commented:

A really interesting paper and discussion, that calls into question Ioannidis' 2007 widely cited paper "Why Most Published Research Findings Are False". Definitely worth reading: includes a discussion by D.R. Cox, probably the world's most famous living statistician.

On 2013 Oct 22, Scott D McGinnis commented:

None

On 2013 Oct 23, Larry Wasserman commented:

I agree with Rob that this is an interesting paper. However, it does assume that the p-values are uniform under the null. Hidden biases can compromise this assumption leading to a distribution for the p-value that is skewed towards 0.

On 2013 Oct 23, Hilda Bastian commented:

This paper by Jager and Leek (Jager LR, 2014) challenges Ioannidis' conclusion that "most published research papers are false" (Ioannidis JP, 2005). Ioannidis responds to this discussion, challenging the data and analytical approach here: (Ioannidis JP, 2014). The conclusions of this paper (Ioannidis JP, 2005) were also challenged by Goodman and Greenfield in 2007 (and responded to by Ioannidis JP, 2007). (I discuss this debate in a blog post.)