On 2013 Dec 18, Dorothy V M Bishop commented:

I'm interested in cerebral lateralization in relation to dyslexia, and I would be grateful if the authors could provide additional data that would allow me to relate their work to other findings in the literature. Where atypical lateralization is seen, this could either reflect a reduction in the strength of left-sided lateralization, or inclusion of a higher than usual proportion of individuals with right-sided lateralization (see Illingworth S, Bishop DVM: Atypical cerebral lateralisation in adults with compensated developmental dyslexia demonstrated using functional transcranial Doppler ultrasound. Brain Lang 2009, 111:61-65). It would be good to know how these data compare, and whether the effect size is comparable to previous studies. Could the authors please provide a table showing the laterality indices from vWFA and IFG for all individual subjects in the dyslexic and control groups? I I should add that I think more caution is needed in interpreting the correlational data reported here, given the sample sizes of 15 and 16. For instance, the correlations shown in Figure 4B have overlapping confidence intervals. With N of 15, a correlation of -.12 has 95% CI from -.6 to .42; a correlation of -.66 has 95% CI from -.88 to -.22. Thus the differences between these correlations could be due to sampling error.

On 2013 Dec 18, Dorothy V M Bishop commented:

I'm interested in cerebral lateralization in relation to dyslexia, and I would be grateful if the authors could provide additional data that would allow me to relate their work to other findings in the literature. Where atypical lateralization is seen, this could either reflect a reduction in the strength of left-sided lateralization, or inclusion of a higher than usual proportion of individuals with right-sided lateralization (see Illingworth S, Bishop DVM: Atypical cerebral lateralisation in adults with compensated developmental dyslexia demonstrated using functional transcranial Doppler ultrasound. Brain Lang 2009, 111:61-65). It would be good to know how these data compare, and whether the effect size is comparable to previous studies. Could the authors please provide a table showing the laterality indices from vWFA and IFG for all individual subjects in the dyslexic and control groups? I I should add that I think more caution is needed in interpreting the correlational data reported here, given the sample sizes of 15 and 16. For instance, the correlations shown in Figure 4B have overlapping confidence intervals. With N of 15, a correlation of -.12 has 95% CI from -.6 to .42; a correlation of -.66 has 95% CI from -.88 to -.22. Thus the differences between these correlations could be due to sampling error.