On 2014 Dec 27, Paolo Zamboni commented:

Dear Colleagues,the rate of stenosis in angiography is calculated by comparing the diameter of the stricture with that of the segment immediately preceding it. In the article herein commented, it has been proposed a novel method which compares, along the entire anatomical length of the internal jugular vein, the widest with the narrowest point.However,the jugular in normal cases is characterized by a big variability in size, with >50% variation of the diameter by comparing the bulb with any other point of the vein. This is the reason because the proposed methodology was unable to separate healthy controls from MS cases. If someone should be interested in the assessment of primary venous obstruction please click the link below http://www.pagepressjournals.org/index.php/vl/article/view/vl.2014.4195

On 2014 Dec 27, Paolo Zamboni commented:

Dear Colleagues,the rate of stenosis in angiography is calculated by comparing the diameter of the stricture with that of the segment immediately preceding it. In the article herein commented, it has been proposed a novel method which compares, along the entire anatomical length of the internal jugular vein, the widest with the narrowest point.However,the jugular in normal cases is characterized by a big variability in size, with >50% variation of the diameter by comparing the bulb with any other point of the vein. This is the reason because the proposed methodology was unable to separate healthy controls from MS cases. If someone should be interested in the assessment of primary venous obstruction please click the link below http://www.pagepressjournals.org/index.php/vl/article/view/vl.2014.4195