On 2013 Nov 16, Ellen M Goudsmit commented:

The authors do not define ME and assume equivalence with CFS which is defined more broadly and covers a heterogeneous population. The assumption of equivaleance has yet to be validated. In light of the literature on ME, I note that evidence of differences between this disease and MS have not been discussed, e.g. type and distribution of UBOs on MRI cf Posner, reproduced in the textbook on ME by Hyde, B. Many findings on CFS are inconsistent due to the heterogeneity of the samples so data should be interrpeted with caution. My study comparing 50 patients with ME, 50 with MS and 50 healthy controls showed no differences between the patients groups on a neuroticism scale. Both had higher scores than healthy controls and this was almost certainly due to the inclusion of somatic symptoms to assess neuroticism.

On 2013 Nov 16, Ellen M Goudsmit commented:

The authors do not define ME and assume equivalence with CFS which is defined more broadly and covers a heterogeneous population. The assumption of equivaleance has yet to be validated. In light of the literature on ME, I note that evidence of differences between this disease and MS have not been discussed, e.g. type and distribution of UBOs on MRI cf Posner, reproduced in the textbook on ME by Hyde, B. Many findings on CFS are inconsistent due to the heterogeneity of the samples so data should be interrpeted with caution. My study comparing 50 patients with ME, 50 with MS and 50 healthy controls showed no differences between the patients groups on a neuroticism scale. Both had higher scores than healthy controls and this was almost certainly due to the inclusion of somatic symptoms to assess neuroticism.