On 2014 Feb 07, Dale D O Martin commented:

The novel role of the wild-type function of HTT in regulating autophagy, including myristoylation of the autophagy inducing domain described herein, was recently summarised nicely here: http://www.ncbi.nlm.nih.gov/pubmed/25720962

Posttranslational myristoylation of HTT was first shown using an in vitro tandem reporter assay described here: http://www.ncbi.nlm.nih.gov/pubmed/21965604

On 2014 Feb 07, Dale D O Martin commented:

The videos showing the formation of autophagosomes by myr-HTT-553-585-EGFP can be viewed here:http://hmg.oxfordjournals.org/content/early/2014/01/22/hmg.ddu027/suppl/DC1

In particular, you can see a vesicle arising from the ER (red) here: http://hmg.oxfordjournals.org/content/suppl/2014/01/23/ddu027.DC1/ddu027supp_video4.mp4

On 2014 Feb 07, Dale D O Martin commented:

The videos showing the formation of autophagosomes by myr-HTT-553-585-EGFP can be viewed here:http://hmg.oxfordjournals.org/content/early/2014/01/22/hmg.ddu027/suppl/DC1

In particular, you can see a vesicle arising from the ER (red) here: http://hmg.oxfordjournals.org/content/suppl/2014/01/23/ddu027.DC1/ddu027supp_video4.mp4

On 2014 Feb 07, Dale D O Martin commented:

The novel role of the wild-type function of HTT in regulating autophagy, including myristoylation of the autophagy inducing domain described herein, was recently summarised nicely here: http://www.ncbi.nlm.nih.gov/pubmed/25720962

Posttranslational myristoylation of HTT was first shown using an in vitro tandem reporter assay described here: http://www.ncbi.nlm.nih.gov/pubmed/21965604