2 Matching Annotations
  1. Jul 2018
    1. On 2014 May 23, Germana Bancone commented:

      The authors state that the patient had a low G6PD enzymatic activity "The spectrophotometric assay showed a mildly reduced level of the enzyme: 7.2% (normal range: 8-18%)." Does 7.2% refer to the activity compared to a normal control? Could the authors specify the value expressed in international units per grams of hemoglobin (IU/gHb)? Could the authors explain this line "Though this X-linked disease is known to affect males exclusively, Errico et al., [2] have described it in females as well.", are they referring to G6PD deficiency or to hemolysis caused by ketoacidosis with G6PD deficient subjects?


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  2. Feb 2018
    1. On 2014 May 23, Germana Bancone commented:

      The authors state that the patient had a low G6PD enzymatic activity "The spectrophotometric assay showed a mildly reduced level of the enzyme: 7.2% (normal range: 8-18%)." Does 7.2% refer to the activity compared to a normal control? Could the authors specify the value expressed in international units per grams of hemoglobin (IU/gHb)? Could the authors explain this line "Though this X-linked disease is known to affect males exclusively, Errico et al., [2] have described it in females as well.", are they referring to G6PD deficiency or to hemolysis caused by ketoacidosis with G6PD deficient subjects?


      This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.