On 2014 Nov 02, Swapnil Hiremath commented:

This systematic review, along with its accompanying review was discussed on Oct 21st 2014 in the open online nephrology journal club, #NephJC, on twitter. Introductory comments are available at the NephJC website. It was a great discussion, with more than 20 participants, including nephrologists, cardiologists and residents/fellows from different specialties. A transcript and a curated (i.e. Storified) version of the tweetchat are available from the NephJC website. The highlights of the tweetchat were:

• The investigators and the funding agency (AHRQ) should be commended for attempting to answer these important questions about the role of troponins in patients with chronic kidney disease.

• Most participants rely on a rise in troponin levels to help diagnose acute coronary syndrome in CKD patients, and were disappointed that no evidence was found to support (or refute) this practice.

• The adverse prognostic implications of higher troponin levels, especially in asymptomatic CKD patients was thought to be quite concerning and was the subject of much discussion, with many possible therapeutic management options being raised.

Overall, these reviews answered a few questions, but also brought out many areas where further research needs to be focused. Interested individuals can track and join in the conversation by following @NephJC or #NephJC, or visit the webpage at NephJC.com.

On 2014 Nov 02, Swapnil Hiremath commented:

This systematic review, along with its accompanying review was discussed on Oct 21st 2014 in the open online nephrology journal club, #NephJC, on twitter. Introductory comments are available at the NephJC website. It was a great discussion, with more than 20 participants, including nephrologists, cardiologists and residents/fellows from different specialties. A transcript and a curated (i.e. Storified) version of the tweetchat are available from the NephJC website. The highlights of the tweetchat were:

• The investigators and the funding agency (AHRQ) should be commended for attempting to answer these important questions about the role of troponins in patients with chronic kidney disease.

• Most participants rely on a rise in troponin levels to help diagnose acute coronary syndrome in CKD patients, and were disappointed that no evidence was found to support (or refute) this practice.

• The adverse prognostic implications of higher troponin levels, especially in asymptomatic CKD patients was thought to be quite concerning and was the subject of much discussion, with many possible therapeutic management options being raised.

Overall, these reviews answered a few questions, but also brought out many areas where further research needs to be focused. Interested individuals can track and join in the conversation by following @NephJC or #NephJC, or visit the webpage at NephJC.com.