- Jul 2018
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europepmc.org europepmc.org
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On 2014 Sep 04, Kenneth Witwer commented:
This review covers an important area of research, as saliva is obtained non-invasively and extracellular vesicles including exosomes may be enriched in useful biomarkers. Unfortunately, several apparent errors are repeated throughout the review.
-The type of extracellular vesicle known as an "exosome" is not the same entity as the nucleic acid processing complex of the same name. A confusion of the two seems evident here. Readers will need to consult the sources to determine what information is and is not relevant to extracellular vesicles.
-Intra- and intercellular vesicle trafficking are also conflated, with the Suedhof/Schekman/Rothman Nobel Prize research described as focused on exosomes. Secretory and secreted vesicles are certainly related, but they are distinct.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.
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- Feb 2018
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europepmc.org europepmc.org
-
On 2014 Sep 04, Kenneth Witwer commented:
This review covers an important area of research, as saliva is obtained non-invasively and extracellular vesicles including exosomes may be enriched in useful biomarkers. Unfortunately, several apparent errors are repeated throughout the review.
-The type of extracellular vesicle known as an "exosome" is not the same entity as the nucleic acid processing complex of the same name. A confusion of the two seems evident here. Readers will need to consult the sources to determine what information is and is not relevant to extracellular vesicles.
-Intra- and intercellular vesicle trafficking are also conflated, with the Suedhof/Schekman/Rothman Nobel Prize research described as focused on exosomes. Secretory and secreted vesicles are certainly related, but they are distinct.
This comment, imported by Hypothesis from PubMed Commons, is licensed under CC BY.
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