On 2017 Jan 14, Sin Hang Lee commented:

In a research paper titled “Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine” published by Ivanov et al. in Cell Host Microbe. 2008 Oct 16;4(4):337-49, antibiotic treatment of the specific microbiota has been shown to inhibit TH17 cell differentiation. Perhaps, Strle and colleagues may consider developing microbiological tests for accurate diagnosis of the early infection of Lyme borreliosis in patients with or without skin lesions for timely appropriate antibiotic treatment to prevent excessive TH17 responses and the subsequent autoimmune disorders.

On 2017 Jan 14, Sin Hang Lee commented:

In a research paper titled “Specific microbiota direct the differentiation of IL-17-producing T-helper cells in the mucosa of the small intestine” published by Ivanov et al. in Cell Host Microbe. 2008 Oct 16;4(4):337-49, antibiotic treatment of the specific microbiota has been shown to inhibit TH17 cell differentiation. Perhaps, Strle and colleagues may consider developing microbiological tests for accurate diagnosis of the early infection of Lyme borreliosis in patients with or without skin lesions for timely appropriate antibiotic treatment to prevent excessive TH17 responses and the subsequent autoimmune disorders.