On 2017 Oct 17, Hiroshi Yao commented:

Dear Harald HHW Schmidt, Thank you for your comments on our paper (Int J Mol Sci 2017 Oct 11). I was engaged in our paper (PLoS ONE 2015), when the paper by Kleikers et al. was published. So I could not know this paper at that time, and it was my mistake not to pay attention for this paper during the next 2 years; I am sorry for this. I will comment on this paper in the near future using PubMed Commons. Sincerely yours, Hiroshi Yao, M.D.

On 2017 Oct 12, Harald HHW Schmidt commented:

It is highly surprising that in this review the systematic review and meta-analysis followed by a pre-clinical randomised confirmatory trial which clearly excluded NOX2 as a target in ischemic stroke was overlooked. https://www.nature.com/articles/srep13428

On 2017 Oct 12, Harald HHW Schmidt commented:

It is highly surprising that in this review the systematic review and meta-analysis followed by a pre-clinical randomised confirmatory trial which clearly excluded NOX2 as a target in ischemic stroke was overlooked. https://www.nature.com/articles/srep13428

On 2017 Oct 17, Hiroshi Yao commented:

Dear Harald HHW Schmidt, Thank you for your comments on our paper (Int J Mol Sci 2017 Oct 11). I was engaged in our paper (PLoS ONE 2015), when the paper by Kleikers et al. was published. So I could not know this paper at that time, and it was my mistake not to pay attention for this paper during the next 2 years; I am sorry for this. I will comment on this paper in the near future using PubMed Commons. Sincerely yours, Hiroshi Yao, M.D.