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  1. Last 7 days
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    A VHL-HIF signaling axis orchestrates invariant natural killer T cell development and fate decisions
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    sciencedirect.com/science/article/pii/S1534580726002868
  3. Nov 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hypoxia promotes airway differentiation in the human lung epithelium
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618356/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neuroprotective properties of erythropoietin (Epo) and its receptor (EpoR) in open spinal dysraphism (OSD): an investigation of EpoR expression in a rat OSD model, along with in vitro studies on the neuroprotective effects of Epo on rat spinal cord-derived neural progenitor cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12620314/
  6. Oct 2025
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hypoxia promotes airway differentiation in the human lung epithelium
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    pmc.ncbi.nlm.nih.gov/articles/PMC7618356/
  8. Jul 2025
  9. dx.doi.org dx.doi.org
    Phthalates Impair Estrogenic Regulation of HIF2α and Extracellular Vesicle Secretion by Human Endometrial Stromal Cells
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    dx.doi.org/10.1210/endocr/bqaf087
  10. May 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12055005/
  12. Mar 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EPAS1 induction drives myocardial degeneration in desmoplakin-cardiomyopathy
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    pmc.ncbi.nlm.nih.gov/articles/PMC11872638/
  14. Dec 2024
  15. www.biorxiv.org www.biorxiv.org
    Phthalates Impair Estrogenic Regulation of HIF2α and Extracellular Vesicle Secretion by Human Endometrial Stromal Cells
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    biorxiv.org/content/10.1101/2024.12.12.628185v1
  16. www.cell.com www.cell.com
    Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn’s disease
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    cell.com/cell-host-microbe/fulltext/S1931-3128(24)00443-8
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    Hypoxia-inducible factor 2α promotes pathogenic polarization of stem-like Th2 cells via modulation of phospholipid metabolism
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    sciencedirect.com/science/article/pii/S1074761324004965
  18. Nov 2024
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impacts of low birthweight on kidney development and intergenerational growth of the offspring
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    pmc.ncbi.nlm.nih.gov/articles/PMC11546680/
  20. Sep 2024
  21. www.sciencedirect.com www.sciencedirect.com
    Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism
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    sciencedirect.com/science/article/pii/S2211383524003733
  22. Jul 2024
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    A microbial metabolite inhibits the HIF-2α-ceramide pathway to mediate the beneficial effects of time-restricted feeding on MASH
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    sciencedirect.com/science/article/pii/S1550413124002754
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    VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC11267025/
  25. May 2024
  26. www.sciencedirect.com www.sciencedirect.com
    Candida albicans accelerates atherosclerosis by activating intestinal hypoxia-inducible factor2α signaling
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    sciencedirect.com/science/article/pii/S1931312824001379
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    PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer
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    sciencedirect.com/science/article/pii/S2211124724005047
  28. Mar 2024
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC10925443/
  30. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The Hydrophilic Metabolite UMP Alleviates Obesity Traits through a HIF2α-ACER2-Ceramide Signaling Axis
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    onlinelibrary.wiley.com/doi/10.1002/advs.202309525
  31. Dec 2023
  32. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
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    onlinelibrary.wiley.com/doi/10.1002/advs.202305620
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    Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
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    sciencedirect.com/science/article/pii/S2666379123005591
  34. Nov 2023
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    The hypoxia-inducible factor EPAS1 is required for spermatogonial stem cell function in regenerative conditions
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    sciencedirect.com/science/article/pii/S2589004223025014
  36. Jun 2023
  37. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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    aacrjournals.org/cancerres/article/83/5/735/716680/Enhanced-Glutaminolysis-Drives-Hypoxia-Induced
  38. Mar 2023
  39. www.sciencedirect.com www.sciencedirect.com
    Laminin switches terminal differentiation fate of human trophoblast stem cells under chemically defined culture conditions
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    sciencedirect.com/science/article/pii/S0021925823002922
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    Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis
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    sciencedirect.com/science/article/pii/S2211124723001754
  41. Nov 2022
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanisms governing target search and binding dynamics of hypoxia-inducible factors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9681212/
  43. academic.oup.com academic.oup.com
    Extracellular Vesicles Secreted by Mouse Decidual Cells Carry Critical Information for the Establishment of Pregnancy
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    academic.oup.com/endo/article/163/12/bqac165/6758297
  44. Sep 2022
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemical inhibition of oxygen-sensing prolyl hydroxylases impairs angiogenic competence of human vascular endothelium through metabolic reprogramming
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    ncbi.nlm.nih.gov/pmc/articles/PMC9494243/
  46. Aug 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Hypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE
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    sciencedirect.com/science/article/pii/S2589004222011440
  48. Apr 2022
  49. journals.physiology.org journals.physiology.org
    Hypoxia-inducible factor protects against acute kidney injury via the Wnt/β-catenin signaling pathway
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    journals.physiology.org/doi/full/10.1152/ajprenal.00023.2022
  50. Oct 2021
  51. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuronal deficiency of hypoxia-inducible factor 2α increases hypoxic-ischemic brain injury in neonatal mice
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    onlinelibrary.wiley.com/doi/10.1002/jnr.24943
  52. Aug 2021
  53. www.sciencedirect.com www.sciencedirect.com
    Macrophage HIF-2α suppresses NLRP3 inflammasome activation and alleviates insulin resistance
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    sciencedirect.com/science/article/pii/S2211124721010457
  54. Jun 2021
  55. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms
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    cancerdiscovery.aacrjournals.org/content/11/6/1398
  56. May 2021
  57. www.sciencedirect.com www.sciencedirect.com
    Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity
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    sciencedirect.com/science/article/pii/S1934590920305920
  58. Apr 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor
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    sciencedirect.com/science/article/pii/S2451945621001598
  60. Nov 2020
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription
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    ncbi.nlm.nih.gov/pmc/articles/PMC7641585/
  62. Oct 2020
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pregnancy success in mice requires appropriate cannabinoid receptor signaling for primary decidua formation
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    ncbi.nlm.nih.gov/pmc/articles/PMC7550189/
  64. Sep 2020
  65. mcb.asm.org mcb.asm.org
    DEAD Box Protein Family Member DDX28 Is a Negative Regulator of Hypoxia-Inducible Factor 2α- and Eukaryotic Initiation Factor 4E2-Directed Hypoxic Translation
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    mcb.asm.org/content/40/6/e00610-19
  66. Jan 2020
  67. www.sciencedirect.com www.sciencedirect.com
    Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk
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    sciencedirect.com/science/article/pii/S2211124719315700
  68. www.cell.com www.cell.com
    A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells
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    cell.com/cell-metabolism/fulltext/S1550-4131(19)30664-3
  69. www.sciencedirect.com www.sciencedirect.com
    Adipocyte Hypoxia-Inducible Factor 2α Suppresses Atherosclerosis by Promoting Adipose Ceramide Catabolism
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    sciencedirect.com/science/article/pii/S1550413119305558
  70. www.sciencedirect.com www.sciencedirect.com
    Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer
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    sciencedirect.com/science/article/pii/S2211124718318849
  71. Nov 2017
  72. elifesciences.org elifesciences.org
    HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium
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    elifesciences.org/articles/25217