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Hypoxia promotes airway differentiation in the human lung epithelium

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  DOI: 10.1016/j.stem.2025.09.007
  
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sciencedirect.com/science/article/pii/S1934590925003388
Jul 2025
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Phthalates Impair Estrogenic Regulation of HIF2α and Extracellular Vesicle Secretion by Human Endometrial Stromal Cells

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1. scibot 02 Jul 2025
  
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  DOI: 10.1210/endocr/bqaf087
  
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dx.doi.org/10.1210/endocr/bqaf087
May 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The context-dependent epigenetic and organogenesis programs determine 3D vs. 2D cellular fitness of MYC-driven murine liver cancer cells

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1. scibot 21 May 2025
  
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  DOI: 10.7554/eLife.101299
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12055005/
Mar 2025
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EPAS1 induction drives myocardial degeneration in desmoplakin-cardiomyopathy

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  DOI: 10.1016/j.isci.2025.111895
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11872638/
Dec 2024
www.biorxiv.org www.biorxiv.org

Phthalates Impair Estrogenic Regulation of HIF2α and Extracellular Vesicle Secretion by Human Endometrial Stromal Cells

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1. scibot 21 Dec 2024
  
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  DOI: 10.1101/2024.12.12.628185
  
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biorxiv.org/content/10.1101/2024.12.12.628185v1
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Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn’s disease

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1. scibot 21 Dec 2024
  
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  DOI: 10.1016/j.chom.2024.11.012
  
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cell.com/cell-host-microbe/fulltext/S1931-3128(24)00443-8
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Hypoxia-inducible factor 2α promotes pathogenic polarization of stem-like Th2 cells via modulation of phospholipid metabolism

2
1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.001
  
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2. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.immuni.2024.11.001
  
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sciencedirect.com/science/article/pii/S1074761324004965
Nov 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Impacts of low birthweight on kidney development and intergenerational growth of the offspring

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1. scibot 15 Nov 2024
  
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  DOI: 10.1016/j.isci.2024.111159
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11546680/
Sep 2024
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Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism

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1. scibot 17 Sep 2024
  
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  DOI: 10.1016/j.apsb.2024.09.010
  
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sciencedirect.com/science/article/pii/S2211383524003733
Jul 2024
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A microbial metabolite inhibits the HIF-2α-ceramide pathway to mediate the beneficial effects of time-restricted feeding on MASH

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1. scibot 30 Jul 2024
  
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  DOI: 10.1016/j.cmet.2024.07.004
  
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sciencedirect.com/science/article/pii/S1550413124002754
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway

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1. scibot 27 Jul 2024
  
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  DOI: 10.1016/j.isci.2024.110285
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11267025/
May 2024
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Candida albicans accelerates atherosclerosis by activating intestinal hypoxia-inducible factor2α signaling

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1. scibot 16 May 2024
  
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  DOI: 10.1016/j.chom.2024.04.017
  
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sciencedirect.com/science/article/pii/S1931312824001379
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PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer

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1. scibot 01 May 2024
  
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  DOI: 10.1016/j.celrep.2024.114176
  
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sciencedirect.com/science/article/pii/S2211124724005047
Mar 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury

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1. scibot 16 Mar 2024
  
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  DOI: 10.21203/rs.3.rs-3938716/v1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10925443/
onlinelibrary.wiley.com onlinelibrary.wiley.com

The Hydrophilic Metabolite UMP Alleviates Obesity Traits through a HIF2α-ACER2-Ceramide Signaling Axis

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1. scibot 12 Mar 2024
  
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  DOI: 10.1002/advs.202309525
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202309525
Dec 2023
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Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation

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1. scibot 29 Dec 2023
  
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  DOI: 10.1002/advs.202305620
  
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onlinelibrary.wiley.com/doi/10.1002/advs.202305620
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Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis

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1. scibot 22 Dec 2023
  
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  DOI: 10.1016/j.xcrm.2023.101342
  
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sciencedirect.com/science/article/pii/S2666379123005591
Nov 2023
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The hypoxia-inducible factor EPAS1 is required for spermatogonial stem cell function in regenerative conditions

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1. scibot 28 Nov 2023
  
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  DOI: 10.1016/j.isci.2023.108424
  
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sciencedirect.com/science/article/pii/S2589004223025014
Jun 2023
aacrjournals.org aacrjournals.org

Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer

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1. scibot 03 Jun 2023
  
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  DOI: 10.1158/0008-5472.CAN-22-2045
  
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aacrjournals.org/cancerres/article/83/5/735/716680/Enhanced-Glutaminolysis-Drives-Hypoxia-Induced
Mar 2023
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Laminin switches terminal differentiation fate of human trophoblast stem cells under chemically defined culture conditions

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1. scibot 28 Mar 2023
  
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  DOI: 10.1016/j.jbc.2023.104650
  
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sciencedirect.com/science/article/pii/S0021925823002922
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Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis

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  DOI: 10.1016/j.celrep.2023.112164
  
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sciencedirect.com/science/article/pii/S2211124723001754
Nov 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mechanisms governing target search and binding dynamics of hypoxia-inducible factors

1
1. scibot 30 Nov 2022
  
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  Novus Biologicals, Centennial, CO, #NB100-122
  
  DOI: 10.7554/eLife.75064
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9681212/
academic.oup.com academic.oup.com

Extracellular Vesicles Secreted by Mouse Decidual Cells Carry Critical Information for the Establishment of Pregnancy

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1. scibot 03 Nov 2022
  
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  DOI: 10.1210/endocr/bqac165
  
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academic.oup.com/endo/article/163/12/bqac165/6758297
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Chemical inhibition of oxygen-sensing prolyl hydroxylases impairs angiogenic competence of human vascular endothelium through metabolic reprogramming

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1. scibot 24 Sep 2022
  
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  DOI: 10.1016/j.isci.2022.105086
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9494243/
Aug 2022
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Hypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE

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1. scibot 16 Aug 2022
  
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  DOI: 10.1016/j.isci.2022.104872
  
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sciencedirect.com/science/article/pii/S2589004222011440
Apr 2022
journals.physiology.org journals.physiology.org

Hypoxia-inducible factor protects against acute kidney injury via the Wnt/β-catenin signaling pathway

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1. scibot 30 Apr 2022
  
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  DOI: 10.1152/ajprenal.00023.2022
  
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journals.physiology.org/doi/full/10.1152/ajprenal.00023.2022
Oct 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Neuronal deficiency of hypoxia-inducible factor 2α increases hypoxic-ischemic brain injury in neonatal mice

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1. scibot 18 Oct 2021
  
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  DOI: 10.1002/jnr.24943
  
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onlinelibrary.wiley.com/doi/10.1002/jnr.24943
Aug 2021
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Macrophage HIF-2α suppresses NLRP3 inflammasome activation and alleviates insulin resistance

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1. scibot 25 Aug 2021
  
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  DOI: 10.1016/j.celrep.2021.109607
  
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sciencedirect.com/science/article/pii/S2211124721010457
Jun 2021
cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org

LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms

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1. scibot 29 Jun 2021
  
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  DOI: 10.1158/2159-8290.CD-20-1353
  
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cancerdiscovery.aacrjournals.org/content/11/6/1398
May 2021
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Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity

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1. scibot 09 May 2021
  
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  DOI: 10.1016/j.stem.2020.12.008
  
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sciencedirect.com/science/article/pii/S1934590920305920
Apr 2021
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Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

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1. scibot 28 Apr 2021
  
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  DOI: 10.1016/j.chembiol.2021.04.004
  
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sciencedirect.com/science/article/pii/S2451945621001598
Nov 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription

1
1. scibot 12 Nov 2020
  
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  RRID:AB_10002593
  
  DOI: 10.7554/eLife.53550
  
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  RRID:AB_10002593 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7641585/
Oct 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pregnancy success in mice requires appropriate cannabinoid receptor signaling for primary decidua formation

1
1. scibot 24 Oct 2020
  
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  RRID:AB_10002593
  
  DOI: 10.7554/eLife.61762
  
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  Curator: @evieth
  
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  RRIDCUR:Validated RRID:AB_10002593
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ncbi.nlm.nih.gov/pmc/articles/PMC7550189/
Sep 2020
mcb.asm.org mcb.asm.org

DEAD Box Protein Family Member DDX28 Is a Negative Regulator of Hypoxia-Inducible Factor 2α- and Eukaryotic Initiation Factor 4E2-Directed Hypoxic Translation

1
1. scibot 04 Sep 2020
  
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  anti-HIF-2α
  
  DOI: 10.1128/MCB.00610-19
  
  Resource: (Novus Cat# NB100-122, RRID:AB_10002593)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_10002593
  
  Curator comments: HIF-2 alpha Antibody Novus Cat# NB100-122
  
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  RRID:AB_10002593 RRIDCUR:Missing
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mcb.asm.org/content/40/6/e00610-19
Jan 2020
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Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk

1
1. scibot 13 Jan 2020
  
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  RRID:AB_10002593
  
  DOI: 10.1016/j.celrep.2019.11.079
  
  Resource: (Novus Cat# NB100-122, RRID:AB_10002593)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_10002593
  
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  RRID:AB_10002593 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719315700
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A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells

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1. scibot 13 Jan 2020
  
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  RRID:AB_10002593
  
  DOI: 10.1016/j.cmet.2019.11.020
  
  Resource: (Novus Cat# NB100-122, RRID:AB_10002593)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_10002593
  
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  RRID:AB_10002593 RRIDCUR:Validated
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cell.com/cell-metabolism/fulltext/S1550-4131(19)30664-3
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Adipocyte Hypoxia-Inducible Factor 2α Suppresses Atherosclerosis by Promoting Adipose Ceramide Catabolism

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1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_10002593
  
  DOI: 10.1016/j.cmet.2019.09.016
  
  Resource: (Novus Cat# NB100-122, RRID:AB_10002593)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_10002593
  
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  RRID:AB_10002593 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413119305558
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Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer

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1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_10002593
  
  DOI: 10.1016/j.celrep.2018.11.093
  
  Resource: (Novus Cat# NB100-122, RRID:AB_10002593)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_10002593
  
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  RRID:AB_10002593 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718318849
Nov 2017
elifesciences.org elifesciences.org

HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium

1
1. scibot 08 Nov 2017
  
  in Public
  
  AB_10002593
  
  Curator: @chewbeccax
  
  Resource used:
  
  (Novus Cat# NB100-122, RRID:AB_10002593)
  
  SciCrunch record: RRID:AB_10002593
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_10002593 RRIDCUR:Validated
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elifesciences.org/articles/25217