36 Matching Annotations
  1. Last 7 days
  2. www.biorxiv.org www.biorxiv.org
    Phthalates Impair Estrogenic Regulation of HIF2α and Extracellular Vesicle Secretion by Human Endometrial Stromal Cells
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    1. scibot 21 Dec 2024
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      DOI: 10.1101/2024.12.12.628185

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    biorxiv.org/content/10.1101/2024.12.12.628185v1
  3. www.cell.com www.cell.com
    Intestinal E. coli-produced yersiniabactin promotes profibrotic macrophages in Crohn’s disease
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    1. scibot 21 Dec 2024
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      DOI: 10.1016/j.chom.2024.11.012

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    cell.com/cell-host-microbe/fulltext/S1931-3128(24)00443-8
  4. Dec 2024
  5. www.sciencedirect.com www.sciencedirect.com
    Hypoxia-inducible factor 2α promotes pathogenic polarization of stem-like Th2 cells via modulation of phospholipid metabolism
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    1. scibot 02 Dec 2024
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      DOI: 10.1016/j.immuni.2024.11.001

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      DOI: 10.1016/j.immuni.2024.11.001

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    sciencedirect.com/science/article/pii/S1074761324004965
  6. Nov 2024
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Impacts of low birthweight on kidney development and intergenerational growth of the offspring
    1
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      DOI: 10.1016/j.isci.2024.111159

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    pmc.ncbi.nlm.nih.gov/articles/PMC11546680/
  8. Sep 2024
  9. www.sciencedirect.com www.sciencedirect.com
    Adipose ADM2 ameliorates NAFLD via promotion of ceramide catabolism
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      DOI: 10.1016/j.apsb.2024.09.010

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    sciencedirect.com/science/article/pii/S2211383524003733
  10. Jul 2024
  11. www.sciencedirect.com www.sciencedirect.com
    A microbial metabolite inhibits the HIF-2α-ceramide pathway to mediate the beneficial effects of time-restricted feeding on MASH
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    sciencedirect.com/science/article/pii/S1550413124002754
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VHL loss enhances antitumor immunity by activating the anti-viral DNA-sensing pathway
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      DOI: 10.1016/j.isci.2024.110285

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    ncbi.nlm.nih.gov/pmc/articles/PMC11267025/
  13. May 2024
  14. www.sciencedirect.com www.sciencedirect.com
    Candida albicans accelerates atherosclerosis by activating intestinal hypoxia-inducible factor2α signaling
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      DOI: 10.1016/j.chom.2024.04.017

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    sciencedirect.com/science/article/pii/S1931312824001379
  15. www.sciencedirect.com www.sciencedirect.com
    PRMT1 promotes epigenetic reprogramming associated with acquired chemoresistance in pancreatic cancer
    1
    1. scibot 01 May 2024
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      DOI: 10.1016/j.celrep.2024.114176

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    sciencedirect.com/science/article/pii/S2211124724005047
  16. Mar 2024
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury
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    1. scibot 16 Mar 2024
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      DOI: 10.21203/rs.3.rs-3938716/v1

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    pmc.ncbi.nlm.nih.gov/articles/PMC10925443/
  18. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The Hydrophilic Metabolite UMP Alleviates Obesity Traits through a HIF2α-ACER2-Ceramide Signaling Axis
    1
    1. scibot 12 Mar 2024
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      DOI: 10.1002/advs.202309525

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    onlinelibrary.wiley.com/doi/10.1002/advs.202309525
  19. Dec 2023
  20. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
    1
    1. scibot 29 Dec 2023
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      DOI: 10.1002/advs.202305620

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    onlinelibrary.wiley.com/doi/10.1002/advs.202305620
  21. www.sciencedirect.com www.sciencedirect.com
    Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
    1
    1. scibot 22 Dec 2023
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      DOI: 10.1016/j.xcrm.2023.101342

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    sciencedirect.com/science/article/pii/S2666379123005591
  22. Nov 2023
  23. www.sciencedirect.com www.sciencedirect.com
    The hypoxia-inducible factor EPAS1 is required for spermatogonial stem cell function in regenerative conditions
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.isci.2023.108424

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    sciencedirect.com/science/article/pii/S2589004223025014
  24. Jun 2023
  25. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1158/0008-5472.CAN-22-2045

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    aacrjournals.org/cancerres/article/83/5/735/716680/Enhanced-Glutaminolysis-Drives-Hypoxia-Induced
  26. Mar 2023
  27. www.sciencedirect.com www.sciencedirect.com
    Laminin switches terminal differentiation fate of human trophoblast stem cells under chemically defined culture conditions
    1
    1. scibot 28 Mar 2023
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      DOI: 10.1016/j.jbc.2023.104650

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    sciencedirect.com/science/article/pii/S0021925823002922
  28. www.sciencedirect.com www.sciencedirect.com
    Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis
    1
    1. scibot 02 Mar 2023
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      DOI: 10.1016/j.celrep.2023.112164

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    sciencedirect.com/science/article/pii/S2211124723001754
  29. Nov 2022
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanisms governing target search and binding dynamics of hypoxia-inducible factors
    1
    1. scibot 30 Nov 2022
      Novus Biologicals, Centennial, CO, #NB100-122

      DOI: 10.7554/eLife.75064

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    ncbi.nlm.nih.gov/pmc/articles/PMC9681212/
  31. academic.oup.com academic.oup.com
    Extracellular Vesicles Secreted by Mouse Decidual Cells Carry Critical Information for the Establishment of Pregnancy
    1
    1. scibot 03 Nov 2022
      RRID:AB_10002593

      DOI: 10.1210/endocr/bqac165

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    academic.oup.com/endo/article/163/12/bqac165/6758297
  32. Sep 2022
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemical inhibition of oxygen-sensing prolyl hydroxylases impairs angiogenic competence of human vascular endothelium through metabolic reprogramming
    1
    1. scibot 24 Sep 2022
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      DOI: 10.1016/j.isci.2022.105086

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    ncbi.nlm.nih.gov/pmc/articles/PMC9494243/
  34. Aug 2022
  35. www.sciencedirect.com www.sciencedirect.com
    Hypoxia-induced HMGB1 promotes glioma stem cells self-renewal and tumorigenicity via RAGE
    1
    1. scibot 16 Aug 2022
      RRID:AB_10002593

      DOI: 10.1016/j.isci.2022.104872

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    sciencedirect.com/science/article/pii/S2589004222011440
  36. Apr 2022
  37. journals.physiology.org journals.physiology.org
    Hypoxia-inducible factor protects against acute kidney injury via the Wnt/β-catenin signaling pathway
    1
    1. scibot 30 Apr 2022
      RRID:AB_10002593

      DOI: 10.1152/ajprenal.00023.2022

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    journals.physiology.org/doi/full/10.1152/ajprenal.00023.2022
  38. Oct 2021
  39. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Neuronal deficiency of hypoxia-inducible factor 2α increases hypoxic-ischemic brain injury in neonatal mice
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    1. scibot 18 Oct 2021
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      DOI: 10.1002/jnr.24943

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24943
  40. Aug 2021
  41. www.sciencedirect.com www.sciencedirect.com
    Macrophage HIF-2α suppresses NLRP3 inflammasome activation and alleviates insulin resistance
    1
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      DOI: 10.1016/j.celrep.2021.109607

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    sciencedirect.com/science/article/pii/S2211124721010457
  42. Jun 2021
  43. cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org
    LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms
    1
    1. scibot 29 Jun 2021
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      DOI: 10.1158/2159-8290.CD-20-1353

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    cancerdiscovery.aacrjournals.org/content/11/6/1398
  44. May 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Pathologic HIF1α signaling drives adipose progenitor dysfunction in obesity
    1
    1. scibot 09 May 2021
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      DOI: 10.1016/j.stem.2020.12.008

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    sciencedirect.com/science/article/pii/S1934590920305920
  46. Apr 2021
  47. www.sciencedirect.com www.sciencedirect.com
    Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor
    1
    1. scibot 28 Apr 2021
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      DOI: 10.1016/j.chembiol.2021.04.004

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    sciencedirect.com/science/article/pii/S2451945621001598
  48. Nov 2020
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ARID1A loss in adult hepatocytes activates β-catenin-mediated erythropoietin transcription
    1
    1. scibot 12 Nov 2020
      RRID:AB_10002593

      DOI: 10.7554/eLife.53550

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    ncbi.nlm.nih.gov/pmc/articles/PMC7641585/
  50. Oct 2020
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pregnancy success in mice requires appropriate cannabinoid receptor signaling for primary decidua formation
    1
    1. scibot 24 Oct 2020
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      DOI: 10.7554/eLife.61762

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    ncbi.nlm.nih.gov/pmc/articles/PMC7550189/
  52. Sep 2020
  53. mcb.asm.org mcb.asm.org
    DEAD Box Protein Family Member DDX28 Is a Negative Regulator of Hypoxia-Inducible Factor 2α- and Eukaryotic Initiation Factor 4E2-Directed Hypoxic Translation
    1
    1. scibot 04 Sep 2020
      anti-HIF-2α

      DOI: 10.1128/MCB.00610-19

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      Curator comments: HIF-2 alpha Antibody Novus Cat# NB100-122

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    mcb.asm.org/content/40/6/e00610-19
  54. Jan 2020
  55. www.sciencedirect.com www.sciencedirect.com
    Mesothelial Cell HIF1α Expression Is Metabolically Downregulated by Metformin to Prevent Oncogenic Tumor-Stromal Crosstalk
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.celrep.2019.11.079

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    sciencedirect.com/science/article/pii/S2211124719315700
  56. www.cell.com www.cell.com
    A Variant of SLC1A5 Is a Mitochondrial Glutamine Transporter for Metabolic Reprogramming in Cancer Cells
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.cmet.2019.11.020

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    cell.com/cell-metabolism/fulltext/S1550-4131(19)30664-3
  57. www.sciencedirect.com www.sciencedirect.com
    Adipocyte Hypoxia-Inducible Factor 2α Suppresses Atherosclerosis by Promoting Adipose Ceramide Catabolism
    1
    1. scibot 13 Jan 2020
      RRID:AB_10002593

      DOI: 10.1016/j.cmet.2019.09.016

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    sciencedirect.com/science/article/pii/S1550413119305558
  58. www.sciencedirect.com www.sciencedirect.com
    Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_10002593

      DOI: 10.1016/j.celrep.2018.11.093

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      Curator: @evieth

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    sciencedirect.com/science/article/pii/S2211124718318849
  59. Nov 2017
  60. elifesciences.org elifesciences.org
    HIF-1α is required for disturbed flow-induced metabolic reprogramming in human and porcine vascular endothelium
    1
    1. scibot 08 Nov 2017
      AB_10002593

      Curator: @chewbeccax

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    elifesciences.org/articles/25217