121 Matching Annotations
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    A GluN2B disease-associated variant promotes the degradation of NMDA receptors via autophagy
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  3. Dec 2025
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    Dual roles of TRPV2 in the innate immune response to cytosolic DNA: Arresting dormant and boosting activated STING
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  5. Nov 2025
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    Gastrocnemius Myofiber Type and Mitochondrial Alterations Associated With Peripheral Artery Disease Severity
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    NIPSNAP1 and NIPSNAP2 Act as “Eat Me” Signals for Mitophagy
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  9. Jul 2025
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    PINK1 Loss of Function Selectively Alters the Mitochondrial‐Derived Vesicle Pathway
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  11. May 2025
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    mTOR inhibition in Q175 Huntington’s disease model mice facilitates neuronal autophagy and mutant huntingtin clearance
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    Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses
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    Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation
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    STING mediates lysosomal quality control and recovery through its proton channel function and TFEB activation in lysosomal storage disorders
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    Particle uptake by macrophages triggers bifurcated transcriptional pathways that differentially regulate inflammation and lysosomal gene expression
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    Lysosomal LRRC8 complex regulates lysosomal pH, morphology and systemic glucose metabolism
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    TBC1D24 interacts with the v-ATPase and regulates intraorganellar pH in neurons
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    Unveiling the physiological impact of ESCRT-dependent autophagosome closure by targeting the VPS37A ubiquitin E2 variant-like domain
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    Lysosomal damage triggers a p38 MAPK-dependent phosphorylation cascade to promote lysophagy via the small heat shock protein HSP27
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    Non-autophagic Golgi-LC3 lipidation facilitates TFE3 stress response against Golgi dysfunction
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  29. Sep 2024
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    Highlights from MBoC Selection: Differential reliance of CTD-nuclear envelope phosphatase 1 on its regulatory subunit in ER lipid synthesis and storage
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    Force-induced dephosphorylation activates the cochaperone BAG3 to coordinate protein homeostasis and membrane traffic
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    Contactin -Associated protein1 Regulates Autophagy by Modulating the PI3K/AKT/mTOR Signaling Pathway and ATG4B Levels in Vitro and in Vivo
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    Sustained generation of neurons destined for neocortex with oxidative metabolic upregulation upon filamin abrogation
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    Targeted protein degradation systems to enhance Wnt signaling
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  37. May 2024
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    KAT8 compound inhibition inhibits the initial steps of PINK1-dependant mitophagy
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    Adiponectin inhibits the progression of obesity-associated papillary thyroid carcinoma through autophagy
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    Autophagy preferentially degrades non-fibrillar polyQ aggregates
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    Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy
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    Migrasomal autophagosomes relieve endoplasmic reticulum stress in glioblastoma cells
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  45. Dec 2023
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    MORG1 limits mTORC1 signaling by inhibiting Rag GTPases
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    Dendritic distribution of autophagosomes underlies pathway-selective induction of LTD
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    ApoE4-dependent lysosomal cholesterol accumulation impairs mitochondrial homeostasis and oxidative phosphorylation in human astrocytes
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  50. Sep 2023
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    Analysis of autophagy deficiency and cytotoxicity in autophagy-deficient human embryonic stem cell-derived neurons
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  52. Aug 2023
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    Metformin rescues migratory deficits of cells derived from patients with periventricular heterotopia
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  55. Jun 2023
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    Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis
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    Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
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  59. Apr 2023
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    NAD depletion mediates cytotoxicity in human neurons with autophagy deficiency
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    Microwave hyperthermia represses human papillomavirus oncoprotein activity and induces cell death due to cell stress in 3D tissue models of anogenital precancers and cancers
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  62. Mar 2023
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    MFN1 augmentation prevents retinal degeneration in a Charcot-Marie-Tooth type 2A mouse model
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  64. Feb 2023
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    Exercise-activated hepatic autophagy via the FN1-α5β1 integrin pathway drives metabolic benefits of exercise
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    ARMS-NF-κB signaling regulates intracellular ROS to induce autophagy-associated cell death upon oxidative stress
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    Hypoxic postconditioning restores mitophagy against transient global cerebral ischemia via Parkin-induced posttranslational modification of TBK1
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  68. Jan 2023
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    The selective autophagy adaptor p62/SQSTM1 forms phase condensates regulated by HSP27 that facilitate the clearance of damaged lysosomes via lysophagy
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    Pyruvate dehydrogenase kinase supports macrophage NLRP3 inflammasome activation during acute inflammation
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  71. Nov 2022
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    Autophagy promotes cell survival by maintaining NAD levels
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    Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma
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  74. Oct 2022
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    Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D
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  76. Jul 2022
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    Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy
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  79. Jun 2022
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    Deficiency of C1QL1 reduced murine ovarian follicle reserve through intraovarian and endocrine control
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  81. Apr 2022
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    The Enantiomer of Allopregnanolone Prevents Pressure-Mediated Retinal Degeneration Via Autophagy
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  83. Mar 2022
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    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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  86. Jan 2022
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    Brain-derived autophagosome profiling reveals the engulfment of nucleoid-enriched mitochondrial fragments by basal autophagy in neurons
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  89. Dec 2021
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    Persistent coxsackievirus B1 infection triggers extensive changes in the transcriptome of human pancreatic ductal cells
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  91. Nov 2021
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    TNF leads to mtDNA release and cGAS/STING-dependent interferon responses that support inflammatory arthritis
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  93. Oct 2021
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    Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation
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    Inositol serves as a natural inhibitor of mitochondrial fission by directly targeting AMPK
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  97. Aug 2021
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    MicroRNA 223 Targeting ATG16L1 Affects Microglial Autophagy in the Kainic Acid Model of Temporal Lobe Epilepsy
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    Human Immunodeficiency Virus Type-1 single-stranded RNA activates the NLRP3 inflammasome and impairs autophagic clearance of damaged mitochondria in human microglia
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    Mst‐1 deficiency promotes post‐traumatic spinal motor neuron survival via enhancement of autophagy flux
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  106. Jul 2021
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    Stimulation of Hair Growth by Small Molecules that Activate Autophagy
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    Early onset effects of single substrate accumulation recapitulate major features of LSD in patient-derived lysosomes
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  111. Jun 2021
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    Mitochondrial-derived vesicles compensate for loss of LC3-mediated mitophagy
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    Impact of differential and time-dependent autophagy activation on therapeutic efficacy in a model of Huntington disease
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  114. May 2021
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    The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding
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  116. Apr 2021
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    Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons
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    The neurosteroid allopregnanolone protects retinal neurons by effects on autophagy and GABRs/GABAA receptors in rat glaucoma models
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    Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis
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  120. Feb 2021
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    VCP/p97 regulates Beclin-1-dependent autophagy initiation
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    The neurosteroid allopregnanolone protects retinal neurons by effects on autophagy and GABRs/GABAA receptors in rat glaucoma models
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    The autophagy gene Atg16L1 is necessary for endometrial decidualization
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  124. Nov 2020
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    Celecoxib-Dependent Neuroprotection in a Rat Model of Transient Middle Cerebral Artery Occlusion (tMCAO) Involves Modifications in Unfolded Protein Response (UPR) and Proteasome
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    A Broad Response to Intracellular Long-Chain Polyphosphate in Human Cells
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  127. Oct 2020
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    The dynamic interplay between ATP/ADP levels and autophagy sustain neuronal migration in vivo
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  129. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Gene therapy with secreted acid alpha-glucosidase rescues Pompe disease in a novel mouse model with early-onset spinal cord and respiratory defects
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  130. Sep 2020
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    The Cation Channel TMEM63B Is an Osmosensor Required for Hearing
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    1. judell 21 Dec 2015
      AB_10003146

      Antibody ID: AB_10003146

      Target Antigen: LC3

      Vendor: Novus Go To Vendor

      Cat Num: NB100-2220

      Proper Citation: (Novus Cat# NB100-2220, RRID:AB_10003146)

      Reference:

      Clonality: unknown

      Clone ID: None

      Host Organism: rabbit

      Comments: manufacturer recommendations: Immunofluorescence, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot; Immunofluorescence; Western Blot; Immunohistochemistry; Immunohistochemistry - fixed; Immunoprecipitation mouse, zebrafish/fish, this antibody reacts with human, rat and mouse lc3 protein, though the mouse detection is weaker than the human no other species have been tested the immunogen used for this antibody production has 100 homology with rat and zebrafish, 92 with mouse, 91 with cow, and 84 with xenopus proteins, bovine, plant, human, rat

      resolver lookup

      RRID:AB_10003146
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    1. judell 17 Dec 2015
      AB_10003146

      Antibody ID: AB_10003146

      Target Antigen: LC3

      Vendor: Novus Go To Vendor

      Cat Num: NB100-2220

      Proper Citation: (Novus Cat# NB100-2220, RRID:AB_10003146)

      Reference:

      Clonality: unknown

      Clone ID: None

      Host Organism: rabbit

      Comments: manufacturer recommendations: Immunofluorescence, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot; Immunofluorescence; Western Blot; Immunohistochemistry; Immunohistochemistry - fixed; Immunoprecipitation mouse, zebrafish/fish, this antibody reacts with human, rat and mouse lc3 protein, though the mouse detection is weaker than the human no other species have been tested the immunogen used for this antibody production has 100 homology with rat and zebrafish, 92 with mouse, 91 with cow, and 84 with xenopus proteins, bovine, plant, human, rat

      resolver lookup

      RRID:AB_10003146
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    jneurosci.org/content/35/14/5724.full