61 Matching Annotations
  1. Last 7 days
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome
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    1. scibot 01 May 2024
      AB_10013602

      DOI: 10.21203/rs.3.rs-4131804/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11030528/
  3. Jan 2024
  4. www.sciencedirect.com www.sciencedirect.com
    ZFP281 controls transcriptional and epigenetic changes promoting mouse pluripotent state transitions via DNMT3 and TET1
    1
    1. scibot 19 Jan 2024
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      DOI: 10.1016/j.devcel.2023.12.018

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    sciencedirect.com/science/article/pii/S1534580723006986
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    Selective Targeting of Human TET1 by Cyclic Peptide Inhibitors: Insights from Biochemical Profiling
    1
    1. scibot 18 Jan 2024
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      DOI: 10.1016/j.bmc.2024.117597

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    sciencedirect.com/science/article/pii/S0968089624000117
  6. Oct 2023
  7. www.embopress.org www.embopress.org
    Epigenetic regulation limits competence of pluripotent stem cell-derived oocytes
    1
    1. scibot 20 Oct 2023
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      DOI: 10.15252/embj.2023113955

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    embopress.org/doi/10.15252/embj.2023113955
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Standardized Computer-Assisted Analysis of 5-hmC Immunoreactivity in Dysplastic Nevi and Superficial Spreading Melanomas
    1
    1. scibot 18 Oct 2023
      RRID:AB_10013602

      DOI: 10.3390/ijms241914711

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    ncbi.nlm.nih.gov/pmc/articles/PMC10572721/
  9. www.sciencedirect.com www.sciencedirect.com
    Allosterically inhibited PFKL via prostaglandin E2 withholds glucose metabolism and ovarian cancer invasiveness
    1
    1. scibot 13 Oct 2023
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    sciencedirect.com/science/article/pii/S2211124723012585
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    TET3 plays a critical role in white adipose development and diet-induced remodeling
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113196

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    sciencedirect.com/science/article/pii/S2211124723012081
  11. Sep 2023
  12. www.sciencedirect.com www.sciencedirect.com
    TET2-mediated mRNA demethylation regulates leukemia stem cell homing and self-renewal
    1
    1. scibot 29 Sep 2023
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      DOI: 10.1016/j.stem.2023.07.001

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    sciencedirect.com/science/article/pii/S1934590923002461
  13. Jul 2023
  14. www.sciencedirect.com www.sciencedirect.com
    Title: TET1 Facilitates Specification of Early Human Lineages including Germ Cells
    1
    1. scibot 15 Jul 2023
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      DOI: 10.1016/j.isci.2023.107191

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    sciencedirect.com/science/article/pii/S2589004223012683
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    Tet2 acts in the lateral habenula to regulate social preference in mice
    1
    1. scibot 06 Jul 2023
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    sciencedirect.com/science/article/pii/S2211124723007064
  16. Jun 2023
  17. www.sciencedirect.com www.sciencedirect.com
    Culture conditions of mouse ESCs impact the tumor appearance in vivo
    1
    1. scibot 22 Jun 2023
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    sciencedirect.com/science/article/pii/S2211124723006563
  18. May 2023
  19. www.sciencedirect.com www.sciencedirect.com
    Site-specific R-loops induce CGG repeat contraction and fragile X gene reactivation
    1
    1. scibot 20 May 2023
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      DOI: 10.1016/j.cell.2023.04.035

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    sciencedirect.com/science/article/pii/S0092867423004695
  20. Feb 2023
  21. www.sciencedirect.com www.sciencedirect.com
    IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment
    1
    1. scibot 03 Feb 2023
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      DOI: 10.1016/j.ccell.2023.01.003

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    sciencedirect.com/science/article/pii/S153561082300003X
  22. Jan 2023
  23. www.sciencedirect.com www.sciencedirect.com
    Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia
    1
    1. scibot 24 Jan 2023
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      DOI: 10.1016/j.celrep.2023.112027

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    sciencedirect.com/science/article/pii/S2211124723000384
  24. Nov 2022
  25. www.sciencedirect.com www.sciencedirect.com
    Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function
    1
    1. scibot 10 Nov 2022
      RRID:AB_10013602

      DOI: 10.1016/j.celrep.2022.111612

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    sciencedirect.com/science/article/pii/S2211124722014814
  26. Sep 2022
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
    1
    1. scibot 02 Sep 2022
      RRID:AB_10013602

      DOI: 10.1158/2159-8290.CD-21-1077

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    ncbi.nlm.nih.gov/pmc/articles/PMC8904298/
  28. Aug 2022
  29. www.sciencedirect.com www.sciencedirect.com
    The intrinsic and extrinsic effects of TET proteins during gastrulation
    1
    1. scibot 02 Aug 2022
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      DOI: 10.1016/j.cell.2022.06.049

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    sciencedirect.com/science/article/pii/S009286742200842X
  30. Jul 2022
  31. www.sciencedirect.com www.sciencedirect.com
    Skeletal progenitors preserve proliferation and self-renewal upon inhibition of mitochondrial respiration by rerouting the TCA cycle
    1
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      DOI: 10.1016/j.celrep.2022.111105

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    sciencedirect.com/science/article/pii/S221112472200907X
  32. Jun 2022
  33. www.sciencedirect.com www.sciencedirect.com
    A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency
    1
    1. scibot 09 Jun 2022
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      DOI: 10.1016/j.celrep.2022.110928

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    sciencedirect.com/science/article/pii/S2211124722007100
  34. Mar 2022
  35. www.sciencedirect.com www.sciencedirect.com
    dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
    1
    1. scibot 02 Mar 2022
      AB_10013602

      DOI: 10.1016/j.celrep.2022.110457

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    sciencedirect.com/science/article/pii/S221112472200184X
  36. www.sciencedirect.com www.sciencedirect.com
    8C-like cells capture the human zygotic genome activation program in vitro
    1
    1. scibot 02 Mar 2022
      RRID:AB_10013602

      DOI: 10.1016/j.stem.2022.01.014

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    sciencedirect.com/science/article/pii/S1934590922000509
  37. Jan 2022
  38. www.sciencedirect.com www.sciencedirect.com
    Opioid receptor signaling suppresses leukemia through both catalytic and non-catalytic functions of TET2
    1
    1. scibot 26 Jan 2022
      RRID:AB_10013602

      DOI: 10.1016/j.celrep.2021.110253

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    sciencedirect.com/science/article/pii/S2211124721017654
  39. Nov 2021
  40. onlinelibrary.wiley.com onlinelibrary.wiley.com
    β2SP/TET2 complex regulates gene 5hmC modification after cerebral ischemia
    1
    1. scibot 30 Nov 2021
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      DOI: 10.1111/jcmm.17060

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    onlinelibrary.wiley.com/doi/10.1111/jcmm.17060
  41. www.sciencedirect.com www.sciencedirect.com
    Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring
    1
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    sciencedirect.com/science/article/pii/S2211124721013851
  42. Aug 2021
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 11 Aug 2021
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      DOI: 10.1016/j.celrep.2018.11.061

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    ncbi.nlm.nih.gov/pmc/articles/PMC6350936/
  44. academic.oup.com academic.oup.com
    Gestational Diabetes Epigenetically Reprograms the Cart Promoter in Fetal Ovary, Causing Subfertility in Adult Life
    1
    1. scibot 03 Aug 2021
      RRID:AB_10013602

      DOI: 10.1210/en.2019-00319

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    academic.oup.com/endo/article/160/7/1684/5506444
  45. Jul 2021
  46. www.nature.com www.nature.com
    α-Ketoglutarate links p53 to cell fate during tumour suppression
    1
    1. scibot 30 Jul 2021
      rabbit anti-5hmC

      DOI: 10.1038/s41586-019-1577-5

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    nature.com/articles/s41586-019-1577-5
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 28 Jul 2021
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    ncbi.nlm.nih.gov/pmc/articles/PMC6364303/
  48. elifesciences.org elifesciences.org
    Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ
    6
    1. scibot 28 Jul 2021
      AB_10013602

      DOI: 10.7554/eLife.21697

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      DOI: 10.7554/eLife.21697

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    elifesciences.org/content/6/e21697
  49. Jun 2021
  50. www.nature.com www.nature.com
    TET1-mediated DNA hydroxymethylation regulates adult remyelination in mice
    1
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      39769

      DOI: 10.1038/s41467-021-23735-3

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    nature.com/articles/s41467-021-23735-3
  51. May 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal
    1
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      DOI: 10.1016/j.stem.2020.04.010

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    sciencedirect.com/science/article/pii/S1934590920301491
  53. www.sciencedirect.com www.sciencedirect.com
    Glutamine Metabolism Controls Chondrocyte Identity and Function
    1
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      DOI: 10.1016/j.devcel.2020.05.001

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    sciencedirect.com/science/article/pii/S1534580720303579
  54. www.sciencedirect.com www.sciencedirect.com
    Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health
    1
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      DOI: 10.1016/j.cmet.2021.03.004

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    sciencedirect.com/science/article/pii/S155041312100111X
  55. Apr 2021
  56. www.sciencedirect.com www.sciencedirect.com
    5-hydroxymethylcytosine is dynamically regulated during forebrain organoid development and aberrantly altered in Alzheimer’s disease
    1
    1. scibot 28 Apr 2021
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      DOI: 10.1016/j.celrep.2021.109042

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    sciencedirect.com/science/article/pii/S2211124721003582
  57. www.sciencedirect.com www.sciencedirect.com
    Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
    1
    1. scibot 17 Apr 2021
      RRID:AB_10013602

      DOI: 10.1016/j.ccell.2020.04.017

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    sciencedirect.com/science/article/pii/S1535610820302166
  58. Feb 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Functionally distinct roles for TET-oxidized 5-methylcytosine bases in somatic reprogramming to pluripotency
    1
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      RRID:AB_10013602

      DOI: 10.1016/j.molcel.2020.11.045

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    sciencedirect.com/science/article/pii/S109727652030887X
  60. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Vitamin C regulates Schwann cell myelination by promoting DNA demethylation of pro‐myelinating genes
    1
    1. scibot 25 Feb 2021
      RRID:AB_10013602

      DOI: 10.1111/jnc.15015

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.15015
  61. Sep 2020
  62. www.sciencedirect.com www.sciencedirect.com
    TET-Mediated Hypermethylation Primes SDH-Deficient Cells for HIF2α-Driven Mesenchymal Transition
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      RRID:AB_10013602

      DOI: 10.1016/j.celrep.2020.03.022

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  63. www.sciencedirect.com www.sciencedirect.com
    Morphine and Naloxone Facilitate Neural Stem Cells Proliferation via a TET1-Dependent and Receptor-Independent Pathway
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    1. scibot 15 Sep 2020
      RRID:AB_10013602

      DOI: 10.1016/j.celrep.2020.02.075

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    sciencedirect.com/science/article/pii/S2211124720302448
  64. Jan 2020
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-molecule targeting of oncogenic FTO demethylase in acute myeloid leukemia
    1
    1. scibot 13 Jan 2020
      RRID:AB_10013602

      DOI: 10.1016/j.ccell.2019.03.006

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    ncbi.nlm.nih.gov/pmc/articles/PMC6812656/
  66. www.sciencedirect.com www.sciencedirect.com
    Rinf Regulates Pluripotency Network Genes and Tet Enzymes in Embryonic Stem Cells
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    1. scibot 13 Jan 2020
      RRID:AB_10013602

      DOI: 10.1016/j.celrep.2019.07.080

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  67. www.sciencedirect.com www.sciencedirect.com
    Non-catalytic Roles of Tet2 Are Essential to Regulate Hematopoietic Stem and Progenitor Cell Homeostasis
    1
    1. scibot 13 Jan 2020
      RRID:AB_10013602

      DOI: 10.1016/j.celrep.2019.07.094

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  68. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_10013602

      DOI: 10.1016/j.celrep.2018.11.061

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  69. www.sciencedirect.com www.sciencedirect.com
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      RRID:AB_10013602

      DOI: 10.1016/j.celrep.2018.11.099

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  70. onlinelibrary.wiley.com onlinelibrary.wiley.com
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      DOI: 10.1002/jnr.24274

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  71. www.sciencedirect.com www.sciencedirect.com
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    sciencedirect.com/science/article/pii/S1535610819301515
  72. Nov 2018
  73. www.sciencedirect.com www.sciencedirect.com
    RSK-MASTL Pathway Delays Meiotic Exit in Mouse Zygotes to Ensure Paternal Chromosome Stability
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  74. www.sciencedirect.com www.sciencedirect.com
    Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate
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    1. scibot 05 Nov 2018
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  77. www.sciencedirect.com www.sciencedirect.com
    R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling
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    sciencedirect.com/science/article/pii/S009286741731382X
  78. Nov 2017
  79. www.sciencedirect.com www.sciencedirect.com
    A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming
    1
    1. scibot 08 Nov 2017
      39769

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  80. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Epigenetic Effects of an Adenosine Derivative in a Wistar Rat Model of Liver Cirrhosis
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    1. scibot 08 Nov 2017
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      Curator: @patriciaelyse_

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    onlinelibrary.wiley.com/doi/10.1002/jcb.26192/full
  81. elifesciences.org elifesciences.org
    Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-γ
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      Curator: @Zeljana_Babic

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    elifesciences.org/content/6/e21697
  82. www.sciencedirect.com www.sciencedirect.com
    An Intrinsic Epigenetic Barrier for Functional Axon Regeneration
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      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S0896627317302465
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Surveillance Mechanism Ensures Repair of DNA Lesions during Zygotic Reprogramming
    1
    1. scibot 08 Nov 2017
      39769

      Curator: @bandrow

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    ncbi.nlm.nih.gov/pmc/articles/PMC5161750/