83 Matching Annotations
  1. Mar 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NN-01-195, a novel conjugate of HSP90 and AURKA inhibitors, effectively targets solid tumors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12977774/
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    Lipid overload triggers PERK-ALCAT1-mediated mitophagy failure in hepatocytes
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    sciencedirect.com/science/article/pii/S2589004226004438
  4. Jan 2026
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LncRNA DANCR Activates p38/mTOR‐Mediated Autophagy via ANXA2 to Exacerbate Oxygen‐Induced Retinal Neovascularization in Mice
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  6. Dec 2025
  7. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Liprin-α1 enhances PHLDB3 oncogenic function in colorectal cancer via activation of mTORC2-AKT1 pathway
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    sciencedirect.com:5037/science/article/pii/S2211124725014949
  8. Oct 2025
  9. www.biorxiv.org www.biorxiv.org
    CDK4/6 Inhibition Reverses MEIS2 Suppression of CRL4CRBN to Enhance Immunomodulatory Drug Therapy in Multiple Myeloma
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    biorxiv.org/content/10.1101/2025.10.14.681840v1
  10. Aug 2025
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    Platycodin D targets ZNF70 to inhibit NLRP3 inflammasome and STAT3 signaling pathway to ameliorate colitis
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    sciencedirect.com/science/article/pii/S1567576925014134
  12. Apr 2025
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    Red blood cells undergo lytic programmed cell death involving NLRP3
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  14. Mar 2025
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    Protocol to modulate SUMOylation of a specific protein in budding yeast using chemical genetic approaches
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    sciencedirect.com/science/article/pii/S2666166725000814
  16. Sep 2024
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    Targeting APT2 improves MAVS palmitoylation and antiviral innate immunity
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  18. Jul 2024
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    The polySUMOylation axis promotes nucleolar release of Tof2 for mitotic exit
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  20. Apr 2024
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    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
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  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  23. Mar 2024
  24. rupress.org rupress.org
    Rab32 family proteins regulate autophagosomal components recycling
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  25. Feb 2024
  26. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
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    biorxiv.org/content/10.1101/2023.12.05.570182v1
  27. Jan 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Unique transcriptional profiles underlie osteosarcomagenesis driven by different p53 mutants
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    ncbi.nlm.nih.gov/pmc/articles/PMC10524763/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ULK phosphorylation of STX17 controls autophagosome maturation via FLNA
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    ncbi.nlm.nih.gov/pmc/articles/PMC10316704/
  30. Dec 2023
  31. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transgelin Promotes Glioblastoma Stem Cell Hypoxic Responses and Maintenance Through p53 Acetylation
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    onlinelibrary.wiley.com/doi/10.1002/advs.202305620
  32. Sep 2023
  33. link.springer.com link.springer.com
    SMYD2 regulates vascular smooth muscle cell phenotypic switching and intimal hyperplasia via interaction with myocardin
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    link.springer.com/article/10.1007/s00018-023-04883-9
  34. Jun 2023
  35. 52.53.155.43 52.53.155.43
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    LZTR1 mutation mediates oncogenesis through stabilization of EGFR and AXL
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  37. May 2023
  38. 52.53.155.43 52.53.155.43
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    DUSP4 promotes esophageal squamous cell carcinoma progression by dephosphorylating HSP90β
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SMYD2 Regulates Vascular Smooth Muscle Cell Phenotypic Switching and Intimal Hyperplasia via Interaction with Myocardin
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    ncbi.nlm.nih.gov/pmc/articles/PMC10120764/
  41. Mar 2023
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    Synaptotagmin-3 interactions with GluA2 mediate brain damage and impair functional recovery in stroke
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  43. Feb 2023
  44. 52.53.155.43 52.53.155.43
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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of PBRM1 alters promoter histone modifications and activates ALDH1A1 to drive renal cell carcinoma
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  46. link.springer.com link.springer.com
    Transmission of NLRP3-IL-1β Signals in Cerebral Ischemia and Reperfusion Injury: from Microglia to Adjacent Neuron and Endothelial Cells via IL-1β/IL-1R1/TRAF6
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  47. Dec 2022
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    The US9-Derived Protein gPTB9TM Modulates APP Processing Without Targeting Secretase Activities
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    Lysine crotonylation regulates leucine-deprivation-induced autophagy by a 14-3-3ε-PPM1B axis
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  50. Nov 2022
  51. www.cell.com www.cell.com
    Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
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  52. Jun 2022
  53. 52.53.155.43 52.53.155.43
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  54. Apr 2022
  55. www.nature.com www.nature.com
    Recycling of autophagosomal components from autolysosomes by the recycler complex
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    nature.com/articles/s41556-022-00861-8
  56. Mar 2022
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Binding blockade between TLN1 and integrin β1 represses triple-negative breast cancer
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  58. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15758
  59. Jan 2022
  60. www.sciencedirect.com www.sciencedirect.com
    Compartmentalized control of Cdk1 drives mitotic spindle assembly
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  61. Dec 2021
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation
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    ncbi.nlm.nih.gov/pmc/articles/PMC8641947/
  63. Nov 2021
  64. onlinelibrary.wiley.com onlinelibrary.wiley.com
    β2SP/TET2 complex regulates gene 5hmC modification after cerebral ischemia
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    onlinelibrary.wiley.com/doi/10.1111/jcmm.17060
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TAZ inhibits glucocorticoid receptor and coordinates hepatic glucose homeostasis in normal physiological states
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    ncbi.nlm.nih.gov/pmc/articles/PMC8555985/
  66. Oct 2021
  67. journals.sagepub.com journals.sagepub.com
    Astrocytic Hydrogen Sulfide Regulates Supraoptic Cellular Activity in the Adaptive Response of Lactating Rats to Chronic Social Stress - Dongyang Li, Haitao Liu, Hongyang Wang, Shuwei Jia, Xiaoran Wang, Shuo Ling, Guichuan Chen, Xiaoyu Liu, Yu-Feng Wang, 2021
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  68. Sep 2021
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FKBP51 Affects TNF-Related Apoptosis Inducing Ligand Response in Melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC8473884/
  70. Aug 2021
  71. www.sciencedirect.com www.sciencedirect.com
    Oligodendroglial ring finger protein Rnf43 is an essential injury-specific regulator of oligodendrocyte maturation
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    Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6306312/
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  77. Jul 2021
  78. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Cystatin C Improves Blood‐Brain Barrier Integrity After Ischemic Brain Injury in Mice
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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14894
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    An Adversarial DNA N6-Methyladenine-Sensor Network Preserves Polycomb Silencing
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    ncbi.nlm.nih.gov/pmc/articles/PMC6591016/
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    BRAF Splice Variant Resistance to RAF Inhibitor Requires Enhanced MEK Association
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    ncbi.nlm.nih.gov/pmc/articles/PMC6261462/
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    MicroRNA miR-29c regulates RAG1 expression and modulates V(D)J recombination during B cell development
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  83. Jun 2021
  84. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Surface AMP deaminase 2 as a novel regulator modifying extracellular adenine nucleotide metabolism
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002658RR
  85. Mar 2021
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    Centromeric chromatin integrity is compromised by loss of Cdk5rap2, a transcriptional activator of CENP-A
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  87. Feb 2021
  88. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF‐κB and TNF‐α/TNFR1/NF‐κB pathways
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15261
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting NF-κB by the Cell-Permeable NEMO-Binding Domain Peptide Improves Albuminuria and Renal Lesions in an Experimental Model of Type 2 Diabetic Nephropathy
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    Bach1-induced suppression of angiogenesis is dependent on the BTB domain
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    ncbi.nlm.nih.gov/pmc/articles/PMC6948167/
  91. Jan 2021
  92. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Monomeric/dimeric forms of Fgf15/FGF19 show differential activity in hepatocyte proliferation and metabolic function
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202002203R
  93. Nov 2020
  94. www.sciencedirect.com www.sciencedirect.com
    Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer
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  95. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Unbiased Proteomic Screening Identifies a Novel Role for the E3 Ubiquitin Ligase Nedd4‐2 in Translational Suppression During ER Stress
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    onlinelibrary.wiley.com/doi/10.1111/jnc.15219
  96. Oct 2020
  97. academic.oup.com academic.oup.com
    Mechanisms by which membrane and nuclear ER alpha inhibit adipogenesis in cells isolated from female mice
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  98. journals.sagepub.com journals.sagepub.com
    Alleviation of Cerebral Infarction of Rats With Middle Cerebral Artery Occlusion by Inhibition of Aquaporin 4 in the Supraoptic Nucleus - Dan Cui, Shuwei Jia, Jiawei Yu, Dongyang Li, Tong Li, Yang Liu, Jinlong Chang, Xiaoran Wang, Xiaoyu Liu, Yu-Feng Wang, 2020
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  99. Sep 2020
  100. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Involvement of Hyperpolarization-Activated Cyclic Nucleotide-Gated Channel 3 in Oxytocin Neuronal Activity in Lactating Rats With Pup Deprivation - Dongyang Li, Haitao Liu, Xiaoyu Liu, Hongyang Wang, Tong Li, Xiaoran Wang, Shuwei Jia, Ping Wang, Yu-Feng Wang, 2020
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  101. academic.oup.com academic.oup.com
    Activation of CaMKII and GluR1 by the PSD-95-GluN2B Coupling-Dependent Phosphorylation of GluN2B in the Spinal Cord in a Rat Model of Type-2 Diabetic Neuropathic Pain
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    LIM-Homeodomain Transcription Factor LHX4 Is Required for the Differentiation of Retinal Rod Bipolar Cells and OFF-Cone Bipolar Subtypes
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  103. rupress.org rupress.org
    NCAM regulates temporal specification of neural progenitor cells via profilin2 during corticogenesisNCAM regulates temporal NPC specification
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    rupress.org/jcb/article/219/1/e201902164/132733/NCAM-regulates-temporal-specification-of-neural
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    Intersectin-Mediated Clearance of SNARE Complexes Is Required for Fast Neurotransmission
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  105. Jan 2020
  106. www.sciencedirect.com www.sciencedirect.com
    Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway✰
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    sciencedirect.com/science/article/pii/S2352396419306541
  107. onlinelibrary.wiley.com onlinelibrary.wiley.com
    C2‐lacking isoform of Nedd4‐2 regulates excitatory synaptic strength through GluA1 ubiquitination‐independent mechanisms
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14840
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    FMRP Modulates Neural Differentiation through m6A-Dependent mRNA Nuclear Export
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    α-Ketoglutarate-Activated NF-κB Signaling Promotes Compensatory Glucose Uptake and Brain Tumor Development
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  110. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Andrographolide alleviates parkinsonism in MPTP‐PD mice via targeting DRP1‐mediated mitochondrial fission
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14823
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    Bradykinin increases BP in endotoxemic rat: functional and biochemical evidence of angiotensin II AT1/bradykinin B2 receptor heterodimerization
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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  115. Nov 2018
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    Macrophage-Associated PGK1 Phosphorylation Promotes Aerobic Glycolysis and Tumorigenesis
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    The InR/Akt/TORC1 Growth-Promoting Signaling Negatively Regulates JAK/STAT Activity and Migratory Cell Fate during Morphogenesis
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    Molecular Dissection of Neuroligin 2 and Slitrk3 Reveals an Essential Framework for GABAergic Synapse Development
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    sciencedirect.com/science/article/pii/S0896627317309327
  119. Nov 2017
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    HDAC Inhibitor-Induced Mitotic Arrest Is Mediated by Eg5/KIF11 Acetylation
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