83 Matching Annotations
  1. Sep 2026
  2. 54.241.53.176 54.241.53.176
    mct-25-0855_supplementary_table_s3_suppst3-html.html
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    54.241.53.176/4129fc9ddabc594eac734a71780c410dce5907f7/mct-25-0855_supplementary_table_s3_suppst3-html.html
  3. May 2026
  4. link.springer.com link.springer.com
    Loss-of-Function (G603R) Lrp10 Fails to Downregulate mRNA of Pathologic α-Synuclein and Causes Neurodegeneration of Substantia Nigra Dopaminergic Cells in Parkinson’s Disease Knockin Mice
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    link.springer.com/article/10.1007/s11064-026-04762-2
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13130659/
  6. Apr 2026
  7. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Proteasome Inhibitor–Induced Cytotoxic Mechanisms in Canine Pulmonary Adenocarcinoma Cell Lines
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    onlinelibrary.wiley.com/doi/10.1111/vco.70065
  8. Mar 2026
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Oncolytic virotherapy potentiates chemo-PD-1 immunotherapy by engaging chemo-resistant bystander CD8+ T cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12970110/
  10. Sep 2025
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NF1 Loss Promotes EGFR Activation and Confers Sensitivity to EGFR Inhibition in NF1 Mutant Melanoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12221223/pdf/can-24-3904.pdf
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Elevated Transglutaminase-2 in SOX10-Deficient Melanoma Promotes Tumor Onset and Decreases Intratumoral CD4+ T Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12398951/
  13. Aug 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    De novo pyrimidine biosynthesis inhibition synergizes with BCL-XL targeting in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12311037/
  15. Jul 2025
  16. www.biorxiv.org www.biorxiv.org
    Paclitaxel-induced mitotic arrest results in a convergence of apoptotic dependencies that can be safely exploited by BCL-XL degradation to overcome cancer chemoresistance
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    biorxiv.org/content/10.1101/2025.06.24.661170v1
  17. Jun 2025
  18. journals.sagepub.com journals.sagepub.com
    Holothurian Glycosaminoglycan (hGAG) Promoted Bim-Induced Apoptosis in Human Lung Adenocarcinoma A549 Cell Line Through Inhibition of Akt-Mediated FOXO3a Translocation
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    journals.sagepub.com/doi/full/10.1177/15347354251341442
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PRPS activity tunes redox homeostasis in Myc-driven lymphoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12166406/
  20. 52.53.155.43 52.53.155.43
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  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Holothurian Glycosaminoglycan (hGAG) Promoted Bim-Induced Apoptosis in Human Lung Adenocarcinoma A549 Cell Line Through Inhibition of Akt-Mediated FOXO3a Translocation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12144356/
  23. www.sciencedirect.com www.sciencedirect.com
    Redundancy of the OST catalytic subunit facilitates therapeutic targeting of N-glycosylation
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    sciencedirect.com/science/article/pii/S2451945625001667
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    KMT2D coordinates antiviral CD4+ T cell responses through opposing effects on T follicular helper and cytotoxic gene expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12302258/
  25. May 2025
  26. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225008454-main-html.html
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  27. Apr 2025
  28. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced Apoptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964295/
  29. Feb 2025
  30. 52.53.155.43 52.53.155.43
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  31. Dec 2024
  32. www.sciencedirect.com www.sciencedirect.com
    Circular RNAs trigger nonsense-mediated mRNA decay
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    sciencedirect.com/science/article/pii/S109727652400947X
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    Castrate-resistant prostate cancer response to taxane is determined by an HNF1-dependent apoptosis resistance circuit
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    sciencedirect.com/science/article/pii/S2666379124006396
  34. Nov 2024
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    A PROTAC degrader suppresses oncogenic functions of PTK6 inducing apoptosis of breast cancer cells
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    sciencedirect.com/science/article/pii/S2451945624004434
  36. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting BCL2 with Venetoclax Enhances the Efficacy of the KRASG12D Inhibitor MRTX1133 in Pancreatic Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11532783/
  37. Oct 2024
  38. aacrjournals.org aacrjournals.org
    YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma
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    aacrjournals.org/cancerres/article/80/21/4741/645935/YAP-Mediated-Repression-of-HRK-Regulates-Tumor
  39. Sep 2024
  40. www.sciencedirect.com www.sciencedirect.com
    A bispecific antibody targeting EGFR and AXL delays resistance to osimertinib
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    sciencedirect.com/science/article/pii/S2666379124004245
  41. Aug 2024
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fam49b dampens TCR signal strength to regulate survival of positively selected thymocytes and peripheral T cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11333044/
  43. www.sciencedirect.com www.sciencedirect.com
    LAG-3 sustains TOX expression and regulates the CD94/NKG2-Qa-1b axis to govern exhausted CD8 T cell NK receptor expression and cytotoxicity
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    sciencedirect.com/science/article/pii/S0092867424007785
  44. Jul 2024
  45. www.sciencedirect.com www.sciencedirect.com
    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
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    sciencedirect.com/science/article/pii/S1535610824002174
  46. Apr 2024
  47. www.sciencedirect.com www.sciencedirect.com
    Co-inhibition of BET and NAE enhances BIM-dependent apoptosis with augmented cancer therapeutic efficacy
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    sciencedirect.com/science/article/pii/S0006295224001813
  48. Mar 2024
  49. www.sciencedirect.com www.sciencedirect.com
    Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1
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    sciencedirect.com/science/article/pii/S109727652400176X
  50. Dec 2023
  51. www.sciencedirect.com www.sciencedirect.com
    Econazole selectively induces cell death in NF1-homozygous mutant tumor cells
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    sciencedirect.com/science/article/pii/S2666379123005037
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Statin-induced mitochondrial priming sensitizes multiple myeloma cells to BCL2 and MCL1 inhibitors
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    ncbi.nlm.nih.gov/pmc/articles/PMC10704957/
  53. www.sciencedirect.com www.sciencedirect.com
    Liver receptor homolog-1 (NR5A2) orchestrates hepatic inflammation and TNF-induced cell death
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    sciencedirect.com/science/article/pii/S2211124723015255
  54. Nov 2023
  55. www.sciencedirect.com www.sciencedirect.com
    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
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    sciencedirect.com/science/article/pii/S2666379123004846
  56. Oct 2023
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
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    ncbi.nlm.nih.gov/pmc/articles/PMC10570680/
  58. Sep 2023
  59. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Yin-html.html
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    52.53.155.43/3f4c3b7a8c80fd686d3f27ef9d97ee6662a4385e/British J Pharmacology - 2023 - Yin-html.html
  60. Aug 2023
  61. 52.53.155.43 52.53.155.43
    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
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    52.53.155.43/bb31ad2b14838f5cede2aca897c595e2febf2f88/PIIS2666379123002951-html.html
  62. Jun 2023
  63. www.sciencedirect.com www.sciencedirect.com
    The potential therapeutic regimen for overcoming resistance to osimertinib due to rare mutations in NSCLC
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    sciencedirect.com/science/article/pii/S2589004223011823
  64. Feb 2023
  65. www.sciencedirect.com www.sciencedirect.com
    IFNγ signaling sensitizes melanoma cells to BH3 Mimetics
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    sciencedirect.com/science/article/pii/S0022202X23000726
  66. Nov 2022
  67. aacrjournals.org aacrjournals.org
    p53 inhibits Bmi-1-driven self-renewal and defines salivary gland cancer stemness
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    aacrjournals.org/clincancerres/article/28/21/4757/709842/p53-Inhibits-Bmi-1-driven-Self-Renewal-and-Defines
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC9663903/
  69. Oct 2022
  70. 52.53.155.43 52.53.155.43
    ccr-22-1357-html.html
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  71. Sep 2022
  72. www.sciencedirect.com www.sciencedirect.com
    Error-prone protein synthesis recapitulates early symptoms of Alzheimer disease in aging mice
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    sciencedirect.com/science/article/pii/S2211124722012748
  73. www.sciencedirect.com www.sciencedirect.com
    The CX3CL1 intracellular domain exhibits neuroprotection via insulin receptor/ insulin like growth factor receptor signaling
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    sciencedirect.com/science/article/pii/S0021925822009759
  74. Aug 2022
  75. www.sciencedirect.com www.sciencedirect.com
    Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach
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    sciencedirect.com/science/article/pii/S2667237522001485
  76. Jul 2022
  77. www.embopress.org www.embopress.org
    LRH-1/NR5A2 interacts with the glucocorticoid receptor to regulate glucocorticoid resistance
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    embopress.org/doi/10.15252/embr.202154195
  78. Jun 2022
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A
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    ncbi.nlm.nih.gov/pmc/articles/PMC9218363/
  80. www.sciencedirect.com www.sciencedirect.com
    Clioquinol as an inhibitor of JmjC-histone demethylase exhibits common and unique histone methylome and transcriptome between clioquinol and hypoxia
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    sciencedirect.com/science/article/pii/S258900422200788X
  81. May 2022
  82. aacrjournals.org aacrjournals.org
    EGFR inhibition potentiates FGFR inhibitor therapy and overcomes resistance in FGFR2 fusion-positive cholangiocarcinoma
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    aacrjournals.org/cancerdiscovery/article/12/5/1378/694560/EGFR-Inhibition-Potentiates-FGFR-Inhibitor-Therapy
  83. Mar 2022
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 Screens Reveal Epstein-Barr Virus Transformed B-Cell Host Dependency Factors
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    ncbi.nlm.nih.gov/pmc/articles/PMC8938989/
  85. Jan 2022
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effective Menin inhibitor-based combinations against AML with MLL rearrangement or NPM1 mutation (NPM1c)
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    ncbi.nlm.nih.gov/pmc/articles/PMC8752621/
  87. Oct 2021
  88. www.sciencedirect.com www.sciencedirect.com
    Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-α axis
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    sciencedirect.com/science/article/pii/S1934590921003854
  89. Aug 2021
  90. www.nature.com www.nature.com
    Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system
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    nature.com/articles/s41467-021-24821-2
  91. www.sciencedirect.com www.sciencedirect.com
    Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity
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    sciencedirect.com/science/article/pii/S1550413119300117
  92. Jul 2021
  93. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Effects of the Antifungal Agent Ciclopirox in HPV‐Positive Cancer Cells: Repression of Viral E6/E7 Oncogene Expression and Induction of Senescence and Apoptosis
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    onlinelibrary.wiley.com/doi/full/10.1002/ijc.32709
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    Systematic Dissection of the Metabolic-Apoptotic Interface in AML Reveals Heme Biosynthesis to Be a Regulator of Drug Sensitivity
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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC6333829/
  96. www.sciencedirect.com www.sciencedirect.com
    Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells
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    sciencedirect.com/science/article/pii/S221112471930631X
  97. www.sciencedirect.com www.sciencedirect.com
    Kinome-wide RNAi screening for mediators of ABT-199 resistance in breast cancer cells identifies Wee1 as a novel therapeutic target
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    sciencedirect.com/science/article/pii/S1357272521001060
  98. Apr 2021
  99. www.sciencedirect.com www.sciencedirect.com
    Protein Prenylation Drives Discrete Signaling Programs for the Differentiation and Maintenance of Effector Treg Cells
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  100. www.sciencedirect.com www.sciencedirect.com
    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
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    sciencedirect.com/science/article/pii/S1535610820305419
  101. www.sciencedirect.com www.sciencedirect.com
    MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer
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  102. www.sciencedirect.com www.sciencedirect.com
    UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability
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    sciencedirect.com/science/article/pii/S2211124721002801
  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8054351/
  104. Sep 2020
  105. www.sciencedirect.com www.sciencedirect.com
    Treatment-Induced Tumor Dormancy through YAP-Mediated Transcriptional Reprogramming of the Apoptotic Pathway
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    sciencedirect.com/science/article/pii/S1535610819305768
  106. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    5-Azacitidine Induces NOXA to Prime AML Cells for Venetoclax-mediated Apoptosis.
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    clincancerres.aacrjournals.org/content/26/13/3371
  107. www.sciencedirect.com www.sciencedirect.com
    Low-Dose Vertical Inhibition of the RAF-MEK-ERK Cascade Causes Apoptotic Death of KRAS Mutant Cancers
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    sciencedirect.com/science/article/pii/S2211124720307440
  108. www.sciencedirect.com www.sciencedirect.com
    Kinetic Heterogeneity of Cancer Cell Fractional Killing
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    sciencedirect.com/science/article/pii/S2211124720308263
  109. Jan 2020
  110. www.sciencedirect.com www.sciencedirect.com
    TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision
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    sciencedirect.com/science/article/pii/S1074761319304091
  111. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14674
  112. mbio.asm.org mbio.asm.org
    TREM-1 Protects HIV-1-Infected Macrophages from Apoptosis through Maintenance of Mitochondrial Function
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    mbio.asm.org/content/10/6/e02638-19
  113. www.sciencedirect.com www.sciencedirect.com
    Systematic Analysis of Drug Vulnerabilities Conferred by Tumor Suppressor Loss
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  114. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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  115. www.sciencedirect.com www.sciencedirect.com
    BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models
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    sciencedirect.com/science/article/pii/S1535610819302004
  116. www.sciencedirect.com www.sciencedirect.com
    Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R−STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity
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    sciencedirect.com/science/article/pii/S1074761318304758
  117. Nov 2018
  118. www.sciencedirect.com www.sciencedirect.com
    MAST1 Drives Cisplatin Resistance in Human Cancers by Rewiring cRaf-Independent MEK Activation
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    sciencedirect.com/science/article/pii/S1535610818302691
  119. Nov 2017
  120. www.jneurosci.org www.jneurosci.org
    Long Noncoding RNA Malat1 Regulates Cerebrovascular Pathologies in Ischemic Stroke
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    jneurosci.org/content/37/7/1797
  121. www.sciencedirect.com www.sciencedirect.com
    CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors
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    sciencedirect.com/science/article/pii/S1931312817301518
  122. www.sciencedirect.com www.sciencedirect.com
    Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging
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    sciencedirect.com/science/article/pii/S0092867417302465