75 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Global, site-resolved analysis of ubiquitylation occupancy and turnover rate reveals systems properties
    1
    1. scibot 16 Apr 2024
      RRID:AB_10541840

      DOI: 10.1016/j.cell.2024.03.024

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    sciencedirect.com/science/article/pii/S0092867424003155
  3. Dec 2023
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The autophagy protein Atg9 functions in glia and contributes to parkinsonian symptoms in a Drosophila model of Parkinson’s disease
    1
    1. scibot 28 Dec 2023
      RRID:AB_10541840

      DOI: 10.4103/1673-5374.382259

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    ncbi.nlm.nih.gov/pmc/articles/PMC10749615/
  5. Aug 2023
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy ablation in skeletal muscles worsens sepsis-induced muscle wasting, impairs whole-body metabolism, and decreases survival.
    1
    1. scibot 19 Aug 2023
      RRID:AB_10541840

      DOI: 10.1016/j.isci.2023.107475

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    ncbi.nlm.nih.gov/pmc/articles/PMC10425945/
  7. www.sciencedirect.com www.sciencedirect.com
    Identification of KLHDC2 as an efficient proximity-induced degrader of K-RAS, STK33, β-catenin, and FoxP3
    1
    1. scibot 17 Aug 2023
      RRID:AB_10541840

      DOI: 10.1016/j.chembiol.2023.07.006

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    sciencedirect.com/science/article/pii/S2451945623002337
  8. May 2023
  9. www.nature.com www.nature.com
    Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
    1
    1. scibot 05 May 2023
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      DOI: 10.1038/s41467-022-31905-0

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    nature.com/articles/s41467-022-31905-0
  10. Apr 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair
    1
    1. scibot 14 Apr 2023
      RRID:AB_10541840

      DOI: 10.1016/j.molcel.2023.03.021

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    sciencedirect.com/science/article/pii/S1097276523002113
  12. Oct 2022
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy controls Wolbachia infection upon bacterial damage and in aging Drosophila
    1
    1. scibot 27 Oct 2022
      RRID:AB_10541840

      DOI: 10.3389/fcell.2022.976882

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    ncbi.nlm.nih.gov/pmc/articles/PMC9589277/
  14. Sep 2022
  15. www.sciencedirect.com www.sciencedirect.com
    Target protein localization and its impact on PROTAC-mediated degradation
    1
    1. scibot 08 Sep 2022
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      DOI: 10.1016/j.chembiol.2022.08.004

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    sciencedirect.com/science/article/pii/S2451945622003129
  16. Aug 2022
  17. www.sciencedirect.com www.sciencedirect.com
    TMUB1 is an endoplasmic reticulum-resident escortase that promotes the p97-mediated extraction of membrane proteins for degradation
    1
    1. scibot 12 Aug 2022
      RRID:AB_10541840

      DOI: 10.1016/j.molcel.2022.07.006

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    sciencedirect.com/science/article/pii/S1097276522006633
  18. www.sciencedirect.com www.sciencedirect.com
    Glial control of sphingolipid levels sculpts diurnal remodeling in a circadian circuit
    1
    1. scibot 12 Aug 2022
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      DOI: 10.1016/j.neuron.2022.07.016

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    sciencedirect.com/science/article/pii/S0896627322006614
  19. Mar 2022
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of canonical Wnt signalling by the ciliopathy protein MKS1 and the E2 ubiquitin-conjugating enzyme UBE2E1
    1
    1. scibot 04 Mar 2022
      RRID:AB_10541840WB

      DOI: 10.7554/eLife.57593

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    ncbi.nlm.nih.gov/pmc/articles/PMC8880992/
  21. Feb 2022
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sesquiterpene Lactones Potentiate Olaparib-Induced DNA Damage in p53 Wildtype Cancer Cells
    1
    1. scibot 16 Feb 2022
      RRID:AB_10541840

      DOI: 10.3390/ijms23031116

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    ncbi.nlm.nih.gov/pmc/articles/PMC8835362/
  23. www.sciencedirect.com www.sciencedirect.com
    Neuropeptide signaling and SKN-1 orchestrate differential responses of the proteostasis network to dissimilar proteotoxic insults
    2
    1. scibot 11 Feb 2022
      RRID:AB_10541840

      DOI: 10.1016/j.celrep.2022.110350

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    2. scibot 09 Feb 2022
      RRID:AB_10541840

      DOI: 10.1016/j.celrep.2022.110350

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    sciencedirect.com/science/article/pii/S2211124722000663
  24. Jan 2022
  25. www.sciencedirect.com www.sciencedirect.com
    Discovery of small-molecule positive allosteric modulators of Parkin E3 ligase
    1
    1. scibot 06 Jan 2022
      RRID:AB_10541840

      DOI: 10.1016/j.isci.2021.103650

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    sciencedirect.com/science/article/pii/S2589004221016205
  26. Dec 2021
  27. www.sciencedirect.com www.sciencedirect.com
    The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability
    1
    1. scibot 09 Dec 2021
      RRID:AB_10541840

      DOI: 10.1016/j.celrep.2021.110080

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    sciencedirect.com/science/article/pii/S2211124721015710
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    NEAT1 is essential for metabolic changes that promote breast cancer growth and metastasis
    1
    1. scibot 08 Dec 2021
      RRID:AB_10541840

      DOI: 10.1016/j.cmet.2021.11.011

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    sciencedirect.com/science/article/pii/S1550413121005398
  29. Aug 2021
  30. www.sciencedirect.com www.sciencedirect.com
    Coordination of tumor growth and host wasting by tumor-derived Upd3
    1
    1. scibot 18 Aug 2021
      RRID:AB_10541840

      DOI: 10.1016/j.celrep.2021.109553

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    sciencedirect.com/science/article/pii/S2211124721009876
  31. academic.oup.com academic.oup.com
    RNF8 is not required for histone-to-protamine exchange in spermiogenesis
    1
    1. scibot 16 Aug 2021
      AB_10541840

      DOI: 10.1093/biolre/ioab132

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    academic.oup.com/biolreprod/advance-article/doi/10.1093/biolre/ioab132/6315290
  32. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 12 Aug 2021
      RRID:AB_10541840

      DOI: 10.1016/j.chom.2017.09.007

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    sciencedirect.com/science/article/pii/S1931312817303955
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FIP200 Claw Domain Binding to p62 Promotes Autophagosome Formation at Ubiquitin Condensates
    1
    1. scibot 05 Aug 2021
      RRID:AB_10541840

      DOI: 10.1016/j.molcel.2019.01.035

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    ncbi.nlm.nih.gov/pmc/articles/PMC6477179/
  34. www.sciencedirect.com www.sciencedirect.com
    The Nrf2-Keap1 pathway is activated by steroid hormone signaling to govern neuronal remodeling
    1
    1. scibot 04 Aug 2021
      RRID:AB_10541840

      DOI: 10.1016/j.celrep.2021.109466

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    sciencedirect.com/science/article/pii/S2211124721008895
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eeyarestatin Compounds Selectively Enhance Sec61-Mediated Ca2+ Leakage from the Endoplasmic Reticulum
    1
    1. scibot 01 Aug 2021
      RRID:AB_10541840

      DOI: 10.1016/j.chembiol.2019.01.010

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    ncbi.nlm.nih.gov/pmc/articles/PMC6483976/
  36. Jul 2021
  37. academic.oup.com academic.oup.com
    Negative Regulator of Ubiquitin-Like Protein 1 modulates the autophagy-lysosomal pathway via p62 to facilitate the extracellular release of tau following proteasome impairment
    1
    1. scibot 31 Jul 2021
      mouse monoclonal FK2 antibody

      DOI: 10.1093/hmg/ddz255

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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddz255/5613690
  38. www.sciencedirect.com www.sciencedirect.com
    SAC1 regulates autophagosomal phosphatidylinositol-4-phosphate for xenophagy-directed bacterial clearance
    1
    1. scibot 30 Jul 2021
      RRID:AB_10541840

      DOI: 10.1016/j.celrep.2021.109434

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    sciencedirect.com/science/article/pii/S2211124721008512
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 30 Jul 2021
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      DOI: 10.1016/j.chom.2017.09.007

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    ncbi.nlm.nih.gov/pmc/articles/PMC5644667/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    1. scibot 29 Jul 2021
      RRID:AB_10541840

      DOI: 10.7554/eLife.21465

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    ncbi.nlm.nih.gov/pmc/articles/PMC5370187/
  41. elifesciences.org elifesciences.org
    Chlamydia trachomatis-containing vacuole serves as deubiquitination platform to stabilize Mcl-1 and to interfere with host defense
    1
    1. scibot 27 Jul 2021
      AB_10541840

      DOI: 10.7554/eLife.21465

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    elifesciences.org/content/6/e21465
  42. www.sciencedirect.com www.sciencedirect.com
    Proteostasis failure and mitochondrial dysfunction leads to aneuploidy-induced senescence
    1
    1. scibot 03 Jul 2021
      RRID:AB_10541840

      DOI: 10.1016/j.devcel.2021.06.009

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    sciencedirect.com/science/article/pii/S1534580721005165
  43. May 2021
  44. www.sciencedirect.com www.sciencedirect.com
    Ubiquitylation of MYC couples transcription elongation with double-strand break repair at active promoters
    1
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      RRID:AB_10541840

      DOI: 10.1016/j.molcel.2020.12.035

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    sciencedirect.com/science/article/pii/S1097276520309564
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    RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins
    1
    1. scibot 07 May 2021
      RRID:AB_10541840

      DOI: 10.1016/j.molcel.2020.06.023

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    sciencedirect.com/science/article/pii/S1097276520304251
  46. www.cell.com www.cell.com
    The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia
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      RRID:AB_10541840

      DOI: 10.1016/j.isci.2021.102435

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    cell.com/iscience/abstract/S2589-0042(21)00403-X
  47. www.sciencedirect.com www.sciencedirect.com
    Proteasome stress in skeletal muscle mounts a long-range protective response that delays retinal and brain aging
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      RRID:AB_10541840

      DOI: 10.1016/j.cmet.2021.03.005

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    sciencedirect.com/science/article/pii/S1550413121001121
  48. Apr 2021
  49. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Oxidative Damage Underlies Regulatory T Cell Defects in Autoimmunity
    1
    1. scibot 29 Apr 2021
      RRID:AB_10541840

      DOI: 10.1016/j.cmet.2020.07.001

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    sciencedirect.com/science/article/pii/S1550413120303594
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    Coordinate regulation of the senescent state by selective autophagy
    1
    1. scibot 29 Apr 2021
      RRID:AB_10541840

      DOI: 10.1016/j.devcel.2021.04.008

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    sciencedirect.com/science/article/pii/S1534580721003178
  51. Mar 2021
  52. www.sciencedirect.com www.sciencedirect.com
    Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy
    1
    1. scibot 17 Mar 2021
      RRID:AB_10541840

      DOI: 10.1016/j.celrep.2021.108857

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    sciencedirect.com/science/article/pii/S2211124721001716
  53. Feb 2021
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroprotective activity of ursodeoxycholic acid in CHMP2BIntron5 models of frontotemporal dementia
    1
    1. scibot 26 Feb 2021
      RRID:AB_10541840

      DOI: 10.1016/j.nbd.2020.105047

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    ncbi.nlm.nih.gov/pmc/articles/PMC7491204/
  55. Sep 2020
  56. www.sciencedirect.com www.sciencedirect.com
    Ubiquitination of DNA Damage-Stalled RNAPII Promotes Transcription-Coupled Repair
    1
    1. scibot 26 Sep 2020
      RRID:AB_10541840

      DOI: 10.1016/j.cell.2020.02.010

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    sciencedirect.com/science/article/pii/S0092867420301549
  57. elifesciences.org elifesciences.org
    UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity
    1
    1. scibot 26 Sep 2020
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      DOI: 10.7554/eLife.37993

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    Cofilin Loss in Drosophila Muscles Contributes to Muscle Weakness through Defective Sarcomerogenesis during Muscle Growth
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    The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice
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    In Vitro Reconstitution Defines the Minimal Requirements for Cdc48-Dependent Disassembly of the CMG Helicase in Budding Yeast
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    A Drosophila model of neuronal ceroid lipofuscinosis CLN4 reveals a hypermorphic gain of function mechanism
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    PI31 Is an Adaptor Protein for Proteasome Transport in Axons and Required for Synaptic Development
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    Molecular Basis for Autosomal-Dominant Renal Fanconi Syndrome Caused by HNF4A
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    The p97–Ataxin 3 complex regulates homeostasis of the DNA damage response E3 ubiquitin ligase RNF8
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    Ribosomal Proteins Regulate MHC Class I Peptide Generation for Immunosurveillance
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    Mitotic CDK Promotes Replisome Disassembly, Fork Breakage, and Complex DNA Rearrangements
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  79. Nov 2018
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    Cancer Mutations of the Tumor Suppressor SPOP Disrupt the Formation of Active, Phase-Separated Compartments
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    BLM Potentiates c-Jun Degradation and Alters Its Function as an Oncogenic Transcription Factor
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    The Listeriolysin O PEST-like Sequence Co-opts AP-2-Mediated Endocytosis to Prevent Plasma Membrane Damage during Listeria Infection
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    Sense-Antisense lncRNA Pair Encoded by Locus 6p22.3 Determines Neuroblastoma Susceptibility via the USP36-CHD7-SOX9 Regulatory Axis
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    The TORC1-Regulated CPA Complex Rewires an RNA Processing Network to Drive Autophagy and Metabolic Reprogramming
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    PKCα-LSD1-NF-κB-Signaling Cascade Is Crucial for Epigenetic Control of the Inflammatory Response
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    Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability
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    Autophagosomal Content Profiling Reveals an LC3C-Dependent Piecemeal Mitophagy Pathway
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    Ubiquitin Ligase RNF138 Promotes Episodic Ataxia Type 2-Associated Aberrant Degradation of Human Cav2.1 (P/Q-Type) Calcium Channels
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP5/Leon deubiquitinase confines postsynaptic growth by maintaining ubiquitin homeostasis through Ubiquilin
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    A Rab20-Dependent Membrane Trafficking Pathway Controls M. tuberculosis Replication by Regulating Phagosome Spaciousness and Integrity
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    A Class of Environmental and Endogenous Toxins Induces BRCA2 Haploinsufficiency and Genome Instability
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    Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination
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