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37 Matching Annotations

Feb 2025
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Tumor cell–intrinsic Piezo2 drives radioresistance by impairing CD8+ T cell stemness maintenance

1
1. scibot 26 Feb 2025
  
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  RRID:AB_10544692
  
  DOI: 10.1084/jem.20231486
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11338319/
Oct 2024
www.nature.com www.nature.com

QSOX2 Deficiency-induced short stature, gastrointestinal dysmotility and immune dysfunction

1
1. scibot 01 Oct 2024
  
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  RRID:AB_10544692
  
  DOI: 10.1038/s41467-024-52587-w
  
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nature.com/articles/s41467-024-52587-w
Sep 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Mcam stabilizes a luminal progenitor-like breast cancer cell state via Ck2 control and Src/Akt/Stat3 attenuation

1
1. scibot 18 Sep 2024
  
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  AB_10544692
  
  DOI: 10.1038/s41523-024-00687-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11401886/
Aug 2024
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Secreted PTEN binds PLXDC2 on macrophages to drive antitumor immunity and tumor suppression

1
1. scibot 28 Aug 2024
  
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  AB_10544692
  
  DOI: 10.1016/j.devcel.2024.08.003
  
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sciencedirect.com/science/article/pii/S1534580724004866
Jul 2024
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Cellular spermine targets JAK signaling to restrain cytokine-mediated autoimmunity

1
1. scibot 24 Jul 2024
  
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  AB_10544692
  
  DOI: 10.1016/j.immuni.2024.05.025
  
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sciencedirect.com/science/article/pii/S1074761324002796
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Metformin synergizes with gilteritinib in treating FLT3-mutated leukemia via targeting PLK1 signaling

1
1. scibot 17 Jul 2024
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.xcrm.2024.101645
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11293342/
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Excess endocrine growth hormone in acromegaly promotes the aggressiveness and metastasis of triple-negative breast cancer

1
1. scibot 17 Jul 2024
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.isci.2024.110137
  
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sciencedirect.com/science/article/pii/S2589004224013622
Apr 2024
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Development of a chimeric cytokine receptor that captures IL-6 and enhances the antitumor response of CAR-T cells

1
1. scibot 26 Apr 2024
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.xcrm.2024.101526
  
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sciencedirect.com/science/article/pii/S2666379124001952
Mar 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

VISTA promotes the metabolism and differentiation of myeloid-derived suppressor cells by STAT3 and polyamine-dependent mechanisms

1
1. scibot 06 Mar 2024
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.celrep.2023.113661
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10851928/
Dec 2023
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Heterogeneity and transcriptional drivers of triple-negative breast cancer

1
1. scibot 16 Dec 2023
  
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  RRID:AB_10548756
  
  DOI: 10.1016/j.celrep.2023.113564
  
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  Curator: @evieth
  
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  RRID:AB_10544692 RRIDCUR:Unresolved
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sciencedirect.com/science/article/pii/S2211124723015760
Nov 2023
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Preclinical characterization of danatinib as a novel FLT3 inhibitor with excellent efficacy against resistant acute myeloid leukemia

1
1. scibot 28 Nov 2023
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.biopha.2023.115905
  
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sciencedirect.com/science/article/pii/S0753332223017031
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Micheliolide exerts effects in myeloproliferative neoplasms through inhibiting STAT3/5 phosphorylation via covalent binding to STAT3/5 proteins

2
1. scibot 11 Nov 2023
  
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  RRID:AB_10544692
  
  DOI: 10.1097/BS9.0000000000000168
  
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2. scibot 11 Nov 2023
  
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  RRID:AB_10544692
  
  DOI: 10.1097/BS9.0000000000000168
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10629731/
Aug 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Targeting Bcl-xL is a potential therapeutic strategy for extranodal NK/T cell lymphoma

1
1. scibot 04 Aug 2023
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.isci.2023.107369
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10393801/
Jul 2023
www.nature.com www.nature.com

Inhibition of AXL receptor tyrosine kinase enhances brown adipose tissue functionality in mice

1
1. scibot 15 Jul 2023
  
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  RRID:AB_10544692
  
  DOI: 10.1038/s41467-023-39715-8
  
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nature.com/articles/s41467-023-39715-8
Jun 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

N6-methyl-2′-deoxyadenosine promotes self-renewal of BFU-E progenitor in erythropoiesis

1
1. scibot 08 Jun 2023
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.isci.2023.106924
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10239700/
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New scaffolds for type II JAK2 inhibitors overcome the acquired G993A resistance mutation

1
1. scibot 08 Jun 2023
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.chembiol.2023.05.007
  
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sciencedirect.com/science/article/pii/S2451945623001502
May 2023
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Tyrosine kinases compete for growth hormone receptor binding and regulate receptor mobility and degradation

1
1. scibot 10 May 2023
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.celrep.2023.112490
  
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sciencedirect.com/science/article/pii/S2211124723005016
academic.oup.com academic.oup.com

Characterisation of dominant-negative GH receptor variants reveals a potential therapeutic target for short stature

1
1. scibot 04 May 2023
  
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  RRID:AB_10544692
  
  DOI: 10.1093/ejendo/lvad039
  
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academic.oup.com/ejendo/article/188/4/353/7082475
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

S100A8/S100A9 promote progression of multiple myeloma via expansion of megakaryocytes

1
1. scibot 16 Mar 2023
  
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  RRID:AB_10544692
  
  DOI: 10.1158/2767-9764.CRC-22-0368
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10010194/
Nov 2022
academic.oup.com academic.oup.com

Ketone Body Infusion abrogates Growth Hormone Induced Lipolysis and Insulin Resistance

1
1. scibot 18 Nov 2022
  
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  RRID:AB_10544692
  
  DOI: 10.1210/clinem/dgac595
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac595/6761325
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PTP1B is an intracellular checkpoint that limits T cell and CAR T cell anti-tumor immunity

1
1. scibot 02 Sep 2022
  
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  RRID:AB_10544692
  
  DOI: 10.1158/2159-8290.CD-21-0694
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8904293/
Jul 2022
onlinelibrary.wiley.com onlinelibrary.wiley.com

Identification of growth hormone receptor as a relevant target for precision medicine in low-EGFR expressing glioblastoma

1
1. scibot 12 Jul 2022
  
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  RRID:AB_10544692
  
  DOI: 10.1002/ctm2.939
  
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onlinelibrary.wiley.com/doi/10.1002/ctm2.939
Apr 2022
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HIV-1 Vpr drives a tissue residency-like phenotype during selective infection of resting memory T cells

1
1. scibot 14 Apr 2022
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.celrep.2022.110650
  
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sciencedirect.com/science/article/pii/S2211124722004028
Dec 2021
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Local non-pituitary growth hormone is induced with aging and facilitates epithelial damage

1
1. scibot 15 Dec 2021
  
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  RRID:AB_10548756
  
  DOI: 10.1016/j.celrep.2021.110068
  
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sciencedirect.com/science/article/pii/S2211124721015540
Sep 2021
academic.oup.com academic.oup.com

Growth Hormone Receptor (GHR) 6Ω Pseudoexon Activation: a Novel Cause of Severe Growth Hormone Insensitivity

1
1. scibot 04 Sep 2021
  
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  RRID:AB_10544692
  
  DOI: 10.1210/clinem/dgab550
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab550/6329461
www.sciencedirect.com www.sciencedirect.com

Identification of a Kupffer cell subset capable of reverting the T cell dysfunction induced by hepatocellular priming

1
1. scibot 01 Sep 2021
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.immuni.2021.05.005
  
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sciencedirect.com/science/article/pii/S1074761321002119
Jul 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Interleukin 35 ameliorates myocardial ischemia‐reperfusion injury by activating the gp130‐STAT3 axis

1
1. scibot 27 Jul 2021
  
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  RRID:AB_10544692
  
  DOI: 10.1096/fj.201901718RR
  
  Resource: (Cell Signaling Technology Cat# 4322, RRID:AB_10544692)
  
  Curator: @Naa003
  
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  Curator comments: Phospho-Stat5 (Tyr694) (D47E7) XP Rabbit mAb antibody Cell Signaling Technology Cat# 4322
  
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  RRID:AB_10544692 RRIDCUR:Unresolved RRIDCUR:SyntaxError
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onlinelibrary.wiley.com/doi/10.1096/fj.201901718RR
May 2021
academic.oup.com academic.oup.com

A case of Luscan-Lumish syndrome: Possible involvement of enhanced GH signaling

1
1. scibot 10 May 2021
  
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  RRID:AB_10544692
  
  DOI: 10.1210/clinem/dgaa893
  
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academic.oup.com/jcem/article/106/3/718/6009067
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

INCB054828 (pemigatinib), a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3, displays activity against genetically defined tumor models

1
1. scibot 27 Feb 2021
  
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  AB_10544692
  
  DOI: 10.1371/journal.pone.0231877
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7313537/
Nov 2020
www.sciencedirect.com www.sciencedirect.com

Metabolic Reprogramming Induces Germinal Center B Cell Differentiation through Bcl6 Locus Remodeling

1
1. scibot 07 Nov 2020
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.celrep.2020.108333
  
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  Curator: @Naa003
  
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  RRID:AB_10544692 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S221112472031322X
Oct 2020
www.cell.com www.cell.com

Metabolic Reprograming via Deletion of CISH in Human iPSC-Derived NK Cells Promotes In Vivo Persistence and Enhances Anti-tumor Activity

1
1. scibot 16 Oct 2020
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.stem.2020.05.008
  
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  Curator: @evieth
  
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  RRID:AB_10544692 RRIDCUR:Validated
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cell.com/cell-stem-cell/abstract/S1934-5909(20)30206-X
Sep 2020
www.sciencedirect.com www.sciencedirect.com

The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis

1
1. scibot 16 Sep 2020
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.celrep.2020.108158
  
  Resource: (Cell Signaling Technology Cat# 4322, RRID:AB_10544692)
  
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  RRIDCUR:Validated RRID:AB_10544692
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sciencedirect.com/science/article/pii/S2211124720311475
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Pharmacological Activation of Pyruvate Kinase M2 Inhibits CD4+ T Cell Pathogenicity and Suppresses Autoimmunity

1
1. scibot 13 Jan 2020
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.cmet.2019.10.015
  
  Resource: (Cell Signaling Technology Cat# 4322, RRID:AB_10544692)
  
  Curator: @ethanbadger
  
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  RRID:AB_10544692 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413119306060
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Signal Integration and Transcriptional Regulation of the Inflammatory Response Mediated by the GM-/M-CSF Signaling Axis in Human Monocytes

1
1. scibot 13 Jan 2020
  
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  RRID:AB_10544692
  
  DOI: 10.1016/j.celrep.2019.09.035
  
  Resource: (Cell Signaling Technology Cat# 4322, RRID:AB_10544692)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_10544692
  
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  RRID:AB_10544692 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719312239
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A Potent and Selective Small-Molecule Degrader of STAT3 Achieves Complete Tumor Regression In Vivo

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1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_10544692
  
  DOI: 10.1016/j.ccell.2019.10.002
  
  Resource: (Cell Signaling Technology Cat# 4322, RRID:AB_10544692)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_10544692
  
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  RRID:AB_10544692 RRIDCUR:Validated
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RRID:AB_10544692

RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S1535610819304763
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Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells

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1. scibot 13 Jan 2020
  
  in Public
  
  AB_10544692
  
  DOI: 10.1016/j.celrep.2019.05.020
  
  Resource: (Cell Signaling Technology Cat# 4322, RRID:AB_10544692)
  
  Curator: @ethanbadger
  
  SciCrunch record: AB_10544692
  
  What is this?
  
  RRID:AB_10544692 RRIDCUR:Validated
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RRID:AB_10544692

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S221112471930631X