27 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates Rheb and supports amino acid-induced mTORC1 activation
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    1. scibot 21 Dec 2024
      RRID:AB_10545136

      DOI: 10.1016/j.celrep.2024.115101

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    sciencedirect.com/science/article/pii/S2211124724014529
  3. Feb 2024
  4. www.sciencedirect.com www.sciencedirect.com
    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
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    1. scibot 08 Feb 2024
      RRID:AB_10545136

      DOI: 10.1016/j.molcel.2024.01.012

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    sciencedirect.com/science/article/pii/S1097276524000480
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tissue‐specific expression differences in Ras‐related GTP‐binding proteins in male rats
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    1. scibot 03 Feb 2024
      RRID:AB_10545136

      DOI: 10.14814/phy2.15928

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    ncbi.nlm.nih.gov/pmc/articles/PMC10830385/
  6. Dec 2023
  7. www.sciencedirect.com www.sciencedirect.com
    MORG1 limits mTORC1 signaling by inhibiting Rag GTPases
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    1. scibot 16 Dec 2023
      RRID:AB_10545136

      DOI: 10.1016/j.molcel.2023.11.023

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    sciencedirect.com/science/article/pii/S1097276523009681
  8. Nov 2023
  9. www.sciencedirect.com www.sciencedirect.com
    PRMT1 orchestrates with SAMTOR to govern mTORC1 methionine sensing via Arg-methylation of NPRL2
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    1. scibot 28 Nov 2023
      RRID:AB_10545136

      DOI: 10.1016/j.cmet.2023.11.001

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    sciencedirect.com/science/article/abs/pii/S1550413123004114
  10. Sep 2023
  11. www.sciencedirect.com www.sciencedirect.com
    Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells
    1
    1. scibot 30 Sep 2023
      RRID:AB_10545136

      DOI: 10.1016/j.molcel.2023.08.032

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    sciencedirect.com/science/article/pii/S1097276523006950
  12. Apr 2023
  13. www.sciencedirect.com www.sciencedirect.com
    CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth
    1
    1. scibot 06 Apr 2023
      RRID:AB_10545136

      DOI: 10.1016/j.celrep.2023.112316

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    sciencedirect.com/science/article/pii/S2211124723003273
  14. Jan 2023
  15. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D pore-forming activity is redox-sensitive
    1
    1. scibot 21 Jan 2023
      RRID:AB_10545136

      DOI: 10.1016/j.celrep.2023.112008

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    sciencedirect.com/science/article/pii/S2211124723000190
  16. www.sciencedirect.com www.sciencedirect.com
    A central role for regulated protein stability in the control of TFE3 and MITF by nutrients
    1
    1. scibot 06 Jan 2023
      RRID:AB_10545136

      DOI: 10.1016/j.molcel.2022.12.013

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    sciencedirect.com/science/article/pii/S1097276522011704
  17. Dec 2022
  18. www.sciencedirect.com www.sciencedirect.com
    Ring domains are essential for GATOR2-dependent mTORC1 activation
    1
    1. scibot 18 Dec 2022
      RRID:AB_10545136

      DOI: 10.1016/j.molcel.2022.11.021

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    sciencedirect.com/science/article/pii/S1097276522011340
  19. Sep 2022
  20. www.cell.com www.cell.com
    Structure and mechanism of human cystine exporter cystinosin
    1
    1. scibot 17 Sep 2022
      RRID:AB_10545136

      DOI: 10.1016/j.cell.2022.08.020

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    cell.com/cell/fulltext/S0092-8674(22)01114-X
  21. Mar 2022
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model
    1
    1. scibot 11 Mar 2022
      RRID:AB_10545136

      DOI: 10.1152/ajpendo.00236.2021

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    ncbi.nlm.nih.gov/pmc/articles/PMC8714968/
  23. Feb 2022
  24. www.sciencedirect.com www.sciencedirect.com
    E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression
    1
    1. scibot 04 Feb 2022
      RRID:AB_10545136

      DOI: 10.1016/j.molcel.2022.01.002

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    sciencedirect.com/science/article/pii/S1097276522000028
  25. Aug 2021
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 02 Aug 2021
      RRID:AB_10545136

      DOI: 10.1016/j.cmet.2018.08.013

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    ncbi.nlm.nih.gov/pmc/articles/PMC6331339/
  27. Jul 2021
  28. www.sciencedirect.com www.sciencedirect.com
    Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer
    1
    1. scibot 28 Jul 2021
      RRID:AB_10545136

      DOI: 10.1016/j.ccell.2019.01.018

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      Curator: @bandrow

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    sciencedirect.com/science/article/pii/S1535610819300522
  29. www.sciencedirect.com www.sciencedirect.com
    Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway
    1
    1. scibot 22 Jul 2021
      RRID:AB_10545136

      DOI: 10.1016/j.cell.2021.06.028

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    sciencedirect.com/science/article/pii/S0092867421007960
  30. May 2021
  31. www.sciencedirect.com www.sciencedirect.com
    Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity
    1
    1. scibot 07 May 2021
      RRID:AB_10545136

      DOI: 10.1016/j.molcel.2020.10.004

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    sciencedirect.com/science/article/pii/S1097276520306870
  32. www.sciencedirect.com www.sciencedirect.com
    The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction
    1
    1. scibot 05 May 2021
      RRID:AB_10545136

      DOI: 10.1016/j.devcel.2020.08.006

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    sciencedirect.com/science/article/pii/S1534580720306304
  33. Feb 2021
  34. www.cell.com www.cell.com
    Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation
    1
    1. scibot 25 Feb 2021
      RRID:AB_10545136

      DOI: 10.1016/j.molcel.2020.11.036

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    cell.com/molecular-cell/fulltext/S1097-2765(20)30836-4
  35. Sep 2020
  36. elifesciences.org elifesciences.org
    UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity
    1
    1. scibot 15 Sep 2020
      RRID:AB_10545136

      DOI: 10.7554/eLife.37993

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      Curator: @evieth

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    elifesciences.org/articles/37993
  37. www.embopress.org www.embopress.org
    Aster‐C coordinates with COP I vesicles to regulate lysosomal trafficking and activation of mTORC1
    1
    1. scibot 04 Sep 2020
      RagA

      DOI: 10.15252/embr.201949898

      Resource: (Cell Signaling Technology Cat# 4357, RRID:AB_10545136)

      Curator: @Naa003

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      Curator comments: RagA (D8B5) Rabbit mAb antibody Cell Signaling Technology Cat# 4357

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    embopress.org/doi/abs/10.15252/embr.201949898
  38. academic.oup.com academic.oup.com
    Genetic dissection of Ragulator structure and function in amino acid-dependent regulation of mTORC1
    1
    1. scibot 03 Sep 2020
      RagA

      DOI: 10.1093/jb/mvaa076

      Resource: (Cell Signaling Technology Cat# 4357, RRID:AB_10545136)

      Curator: @Naa003

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      Curator comments: RagA (D8B5) Rabbit mAb antibody Cell Signaling Technology Cat# 4357

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    academic.oup.com/jb/article/doi/10.1093/jb/mvaa076/5870373
  39. Jan 2020
  40. www.sciencedirect.com www.sciencedirect.com
    An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis
    1
    1. scibot 13 Jan 2020
      RRID:AB_10545136

      DOI: 10.1016/j.molcel.2019.10.016

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S1097276519307944
  41. Nov 2018
  42. www.sciencedirect.com www.sciencedirect.com
    Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A
    1
    1. scibot 05 Nov 2018
      RRID:AB_10545136

      Curator: @evieth

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    sciencedirect.com/science/article/pii/S155041311830514X
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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    1. scibot 05 Nov 2018
      RRID:AB_10545136

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    ncbi.nlm.nih.gov/pmc/articles/PMC6063731/
  44. www.sciencedirect.com www.sciencedirect.com
    Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations
    1
    1. scibot 05 Nov 2018
      RRID:AB_10545136

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    sciencedirect.com/science/article/pii/S1550413117306290
  45. Nov 2017
  46. www.sciencedirect.com www.sciencedirect.com
    An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer
    1
    1. scibot 08 Nov 2017
      Rabbit monoclonal anti-RagA (D8B5)

      Curator: @chewbeccax

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      (Cell Signaling Technology Cat# 4357S, RRID:AB_10545136)

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    sciencedirect.com/science/article/pii/S0092867416316671