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33 Matching Annotations

Oct 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Pathogenic mutations in ATAD3A cause dysregulation of RagC/D-TFEB axis and disrupt lysosomal homeostasis

1
1. scibot 12 Oct 2026
  
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  RRID:AB_10545136
  
  DOI: 10.64898/2026.09.23.753918
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13622220/
Jul 2026
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NSUN2 integrates glucose and one‑carbon metabolism upstream of Rag GTPase-dependent mTORC1 signaling

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1. scibot 12 Jul 2026
  
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  DOI: 10.1016/j.cellsig.2026.112734
  
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sciencedirect.com/science/article/pii/S0898656826003918
Apr 2026
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Graded activation of the CLEAR network through mTORC1 suppression on cargo-harboring lysosomes

1
1. scibot 11 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117228
  
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sciencedirect.com/science/article/pii/S2211124726003062
Jul 2025
www.science.org www.science.org

Direct sensing of dietary ω-6 linoleic acid through FABP5-mTORC1 signaling

1
1. scibot 25 Jul 2025
  
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  RRID:AB_10545136
  
  DOI: 10.1126/science.adm9805
  
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science.org/doi/10.1126/science.adm9805
May 2025
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YTHDF1 differentiates the contributing roles of mTORC1 in aging

1
1. scibot 29 May 2025
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.molcel.2025.05.003
  
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sciencedirect.com/science/article/pii/S1097276525004083
Dec 2024
www.cell.com www.cell.com

TFEB triggers a matrix degradation and invasion program in triple-negative breast cancer cells upon mTORC1 repression

1
1. scibot 29 Dec 2024
  
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  DOI: 10.1016/j.devcel.2024.12.005
  
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cell.com/developmental-cell/fulltext/S1534-5807(24)00727-5
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The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates Rheb and supports amino acid-induced mTORC1 activation

1
1. scibot 21 Dec 2024
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.celrep.2024.115101
  
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sciencedirect.com/science/article/pii/S2211124724014529
Feb 2024
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The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs

1
1. scibot 08 Feb 2024
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.molcel.2024.01.012
  
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sciencedirect.com/science/article/pii/S1097276524000480
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tissue‐specific expression differences in Ras‐related GTP‐binding proteins in male rats

1
1. scibot 03 Feb 2024
  
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  RRID:AB_10545136
  
  DOI: 10.14814/phy2.15928
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10830385/
Dec 2023
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MORG1 limits mTORC1 signaling by inhibiting Rag GTPases

1
1. scibot 16 Dec 2023
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.molcel.2023.11.023
  
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sciencedirect.com/science/article/pii/S1097276523009681
Nov 2023
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PRMT1 orchestrates with SAMTOR to govern mTORC1 methionine sensing via Arg-methylation of NPRL2

1
1. scibot 28 Nov 2023
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.cmet.2023.11.001
  
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sciencedirect.com/science/article/abs/pii/S1550413123004114
Sep 2023
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Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells

1
1. scibot 30 Sep 2023
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.molcel.2023.08.032
  
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sciencedirect.com/science/article/pii/S1097276523006950
Apr 2023
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CDK5-PRMT1-WDR24 signaling cascade promotes mTORC1 signaling and tumor growth

1
1. scibot 06 Apr 2023
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.celrep.2023.112316
  
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sciencedirect.com/science/article/pii/S2211124723003273
Jan 2023
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Gasdermin D pore-forming activity is redox-sensitive

1
1. scibot 21 Jan 2023
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.celrep.2023.112008
  
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sciencedirect.com/science/article/pii/S2211124723000190
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A central role for regulated protein stability in the control of TFE3 and MITF by nutrients

1
1. scibot 06 Jan 2023
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.molcel.2022.12.013
  
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sciencedirect.com/science/article/pii/S1097276522011704
Dec 2022
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Ring domains are essential for GATOR2-dependent mTORC1 activation

1
1. scibot 18 Dec 2022
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.molcel.2022.11.021
  
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sciencedirect.com/science/article/pii/S1097276522011340
Sep 2022
www.cell.com www.cell.com

Structure and mechanism of human cystine exporter cystinosin

1
1. scibot 17 Sep 2022
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.cell.2022.08.020
  
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cell.com/cell/fulltext/S0092-8674(22)01114-X
Mar 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Intermittent bolus feeding does not enhance protein synthesis, myonuclear accretion, or lean growth more than continuous feeding in a premature piglet model

1
1. scibot 11 Mar 2022
  
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  RRID:AB_10545136
  
  DOI: 10.1152/ajpendo.00236.2021
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8714968/
Feb 2022
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E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression

1
1. scibot 04 Feb 2022
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.molcel.2022.01.002
  
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sciencedirect.com/science/article/pii/S1097276522000028
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 02 Aug 2021
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.cmet.2018.08.013
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6331339/
Jul 2021
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Increased Serine and One-Carbon Pathway Metabolism by PKCλ/ι Deficiency Promotes Neuroendocrine Prostate Cancer

1
1. scibot 28 Jul 2021
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.ccell.2019.01.018
  
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  Curator: @bandrow
  
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sciencedirect.com/science/article/pii/S1535610819300522
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Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway

1
1. scibot 22 Jul 2021
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.cell.2021.06.028
  
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sciencedirect.com/science/article/pii/S0092867421007960
May 2021
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Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity

1
1. scibot 07 May 2021
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.molcel.2020.10.004
  
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sciencedirect.com/science/article/pii/S1097276520306870
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The Rag GTPase Regulates the Dynamic Behavior of TSC Downstream of Both Amino Acid and Growth Factor Restriction

1
1. scibot 05 May 2021
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.devcel.2020.08.006
  
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sciencedirect.com/science/article/pii/S1534580720306304
Feb 2021
www.cell.com www.cell.com

Mitochondrial Threonyl-tRNA Synthetase TARS2 Is Required for Threonine-Sensitive mTORC1 Activation

1
1. scibot 25 Feb 2021
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.molcel.2020.11.036
  
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  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:AB_10545136
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cell.com/molecular-cell/fulltext/S1097-2765(20)30836-4
Sep 2020
elifesciences.org elifesciences.org

UBE3A-mediated p18/LAMTOR1 ubiquitination and degradation regulate mTORC1 activity and synaptic plasticity

1
1. scibot 15 Sep 2020
  
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  RRID:AB_10545136
  
  DOI: 10.7554/eLife.37993
  
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  Curator: @evieth
  
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  RRID:AB_10545136 RRIDCUR:Validated
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elifesciences.org/articles/37993
www.embopress.org www.embopress.org

Aster‐C coordinates with COP I vesicles to regulate lysosomal trafficking and activation of mTORC1

1
1. scibot 04 Sep 2020
  
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  RagA
  
  DOI: 10.15252/embr.201949898
  
  Resource: (Cell Signaling Technology Cat# 4357, RRID:AB_10545136)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_10545136
  
  Curator comments: RagA (D8B5) Rabbit mAb antibody Cell Signaling Technology Cat# 4357
  
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  RRID:AB_10545136 RRIDCUR:Missing
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embopress.org/doi/abs/10.15252/embr.201949898
academic.oup.com academic.oup.com

Genetic dissection of Ragulator structure and function in amino acid-dependent regulation of mTORC1

1
1. scibot 03 Sep 2020
  
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  RagA
  
  DOI: 10.1093/jb/mvaa076
  
  Resource: (Cell Signaling Technology Cat# 4357, RRID:AB_10545136)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_10545136
  
  Curator comments: RagA (D8B5) Rabbit mAb antibody Cell Signaling Technology Cat# 4357
  
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  RRID:AB_10545136 RRIDCUR:Missing
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academic.oup.com/jb/article/doi/10.1093/jb/mvaa076/5870373
Jan 2020
www.sciencedirect.com www.sciencedirect.com

An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis

1
1. scibot 13 Jan 2020
  
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  RRID:AB_10545136
  
  DOI: 10.1016/j.molcel.2019.10.016
  
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  Curator: @ethanbadger
  
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  RRID:AB_10545136 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519307944
Nov 2018
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Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A

1
1. scibot 05 Nov 2018
  
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  RRID:AB_10545136
  
  Curator: @evieth
  
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  RRID:AB_10545136 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S155041311830514X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 05 Nov 2018
  
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  RRID:AB_10545136
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6063731/
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Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations

1
1. scibot 05 Nov 2018
  
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  RRID:AB_10545136
  
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sciencedirect.com/science/article/pii/S1550413117306290
Nov 2017
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An Ancient, Unified Mechanism for Metformin Growth Inhibition in C. elegans and Cancer

1
1. scibot 08 Nov 2017
  
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  Rabbit monoclonal anti-RagA (D8B5)
  
  Curator: @chewbeccax
  
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  (Cell Signaling Technology Cat# 4357S, RRID:AB_10545136)
  
  SciCrunch record: RRID:AB_10545136
  
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  RRID:AB_10545136 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S0092867416316671