56 Matching Annotations
  1. May 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Comprehensive proteogenomic characterization of rare kidney tumors
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    Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancer
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    Combined CDK4/6 and ERK1/2 inhibition enhances anti-tumor activity in NF1-associated plexiform neurofibroma
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  5. Feb 2024
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    Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
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  7. Jan 2024
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    FK506 bypasses the effect of erythroferrone in cancer cachexia skeletal muscle atrophy
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    Recruitment of trimeric eIF2 by phosphatase non-catalytic subunit PPP1R15B
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  10. Dec 2023
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    Synonymous codon usage regulates translation initiation
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    Overexpression of ORMDL3 confers sexual dimorphism in diet-induced non-alcoholic steatohepatitis
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  13. Oct 2023
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    TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory
    1
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    sciencedirect.com/science/article/pii/S1535610823003185
  15. Sep 2023
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    Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor
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  17. Jul 2023
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    Orphan quality control shapes network dynamics and gene expression
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    1. scibot 21 Jul 2023
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  19. Jun 2023
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DAB2IP Is a Bifunctional Tumor Suppressor That Regulates Wild-Type RAS and Inflammatory Cascades in KRAS Mutant Colon Cancer
    1
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  21. Apr 2023
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    Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals
    1
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    sciencedirect.com/science/article/pii/S1550413123001304
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    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
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    sciencedirect.com/science/article/pii/S2666379123001179
  24. Nov 2022
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    LRG1 is an adipokine that promotes insulin sensitivity and suppresses inflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9674348/
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    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
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    Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells
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  28. Sep 2022
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    OMA1-mediated integrated stress response protects against ferroptosis in mitochondrial cardiomyopathy
    1
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      DOI: 10.1016/j.cmet.2022.08.017

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    sciencedirect.com/science/article/pii/S1550413122003606
  30. Jul 2022
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    Gut microbe-derived metabolite trimethylamine N-oxide activates PERK to drive fibrogenic mesenchymal differentiation
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    sciencedirect.com/science/article/pii/S2589004222009415
  32. Jun 2022
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    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    sciencedirect.com/science/article/pii/S109727652200541X
  34. May 2022
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    The non-essential TSC complex component TBC1D7 restricts tissue mTORC1 signaling and brain and neuron growth
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      DOI: 10.1016/j.celrep.2022.110824

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    sciencedirect.com/science/article/pii/S2211124722005952
  36. Apr 2022
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    Betacellulin promotes tumor development and EGFR mutant lung cancer growth by stimulating the EGFR pathway and suppressing apoptosis
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      DOI: 10.1016/j.isci.2022.104211

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    sciencedirect.com/science/article/pii/S2589004222004813
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    Structure-based design of CDC42 effector interaction inhibitors for the treatment of cancer
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    sciencedirect.com/science/article/pii/S221112472200393X
  39. Feb 2022
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    Tethering Piezo channels to the actin cytoskeleton for mechanogating via the cadherin-β-catenin mechanotransduction complex
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      DOI: 10.1016/j.celrep.2022.110342

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    sciencedirect.com/science/article/pii/S2211124722000584
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    Co-adaptor driven assembly of a CUL3 E3 ligase complex
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  42. Jan 2022
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Triple targeting of breast tumors driven by hormonal receptors and HER2
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      DOI: 10.1158/1535-7163.MCT-21-0098

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    ncbi.nlm.nih.gov/pmc/articles/PMC8742793/
  44. Dec 2021
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    Macrophages are metabolically heterogeneous within the tumor microenvironment
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  46. Nov 2021
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    Enteric glial cell heterogeneity regulates intestinal stem cell niches
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      DOI: 10.1016/j.stem.2021.10.004

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    sciencedirect.com/science/article/pii/S1934590921004161
  48. Oct 2021
  49. www.embopress.org www.embopress.org
    Reprogramming of glucocorticoid receptor function by hypoxia
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      DOI: 10.15252/embr.202153083

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    embopress.org/doi/epdf/10.15252/embr.202153083
  50. Sep 2021
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    Circular RNA circLGMN facilitates glioblastoma progression by targeting miR-127-3p/LGMN axis
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      DOI: 10.1016/j.canlet.2021.09.030

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    sciencedirect.com/science/article/pii/S0304383521004912
  52. Aug 2021
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    RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal
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    sciencedirect.com/science/article/pii/S2211124721008688
  54. May 2021
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    Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification
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      DOI: 10.1016/j.stem.2020.11.003

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    sciencedirect.com/science/article/pii/S1934590920305415
  56. Apr 2021
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    FOXA1 Mutations Reveal Distinct Chromatin Profiles and Influence Therapeutic Response in Breast Cancer
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    sciencedirect.com/science/article/pii/S1535610820304141
  58. Feb 2021
  59. www.cell.com www.cell.com
    In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
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      DOI: 10.1016/j.molcel.2020.11.027

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    cell.com/molecular-cell/abstract/S1097-2765(20)30827-3
  60. Jan 2021
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KDM5A mutations identified in autism spectrum disorder using forward genetics
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      DOI: 10.7554/eLife.56883

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    ncbi.nlm.nih.gov/pmc/articles/PMC7755391/
  62. Sep 2020
  63. www.sciencedirect.com www.sciencedirect.com
    Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation
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    sciencedirect.com/science/article/pii/S1097276520300034
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    Hotspots of Aberrant Enhancer Activity in Fibrolamellar Carcinoma Reveal Candidate Oncogenic Pathways and Therapeutic Vulnerabilities
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      DOI: 10.1016/j.celrep.2020.03.073

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    sciencedirect.com/science/article/pii/S2211124720303995
  65. onlinelibrary.wiley.com onlinelibrary.wiley.com
    STAT3‐dependent regulation of the electrogenic Na+/HCO3− cotransporter 1 (NBCe1) functional expression in cortical astrocytes
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      DOI: 10.1002/jcp.29990

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    onlinelibrary.wiley.com/doi/10.1002/jcp.29990
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    Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors
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    Generation of human iPS cell line IBCHi002-A from spinocerebellar ataxia type 3/Machado-Joseph disease patient's fibroblasts
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers
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  70. Jan 2020
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    Functional expression of electrogenic sodium bicarbonate cotransporter 1 (NBCe1) in mouse cortical astrocytes is dependent on S255‐257 and regulated by mTOR
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  73. www.nature.com www.nature.com
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    Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold
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    Generation of human iPS cell line IBCHi001-A from dentatorubral–pallidoluysian atrophy patient's fibroblasts
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  76. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Passive heat therapy protects against endothelial cell hypoxia‐reoxygenation via effects of elevations in temperature and circulating factors
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    Probing the Global Cellular Responses to Lipotoxicity Caused by Saturated Fatty Acids
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  78. www.sciencedirect.com www.sciencedirect.com
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  79. Nov 2018
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    The Histone Chaperones ASF1 and CAF-1 Promote MMS22L-TONSL-Mediated Rad51 Loading onto ssDNA during Homologous Recombination in Human Cells
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    Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity
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    Three-Dimensional Adipose Tissue Imaging Reveals Regional Variation in Beige Fat Biogenesis and PRDM16-Dependent Sympathetic Neurite Density
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  84. Nov 2017
  85. www.sciencedirect.com www.sciencedirect.com
    Genetic Depletion of Adipocyte Creatine Metabolism Inhibits Diet-Induced Thermogenesis and Drives Obesity
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