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Integrated network pharmacology, transcriptomics, and molecular simulations reveal polydatin protects against aortic dissection associated with PPARγ/Nrf2-related antioxidant signaling

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sciencedirect.com/science/article/pii/S0006291X26015044
Oct 2026
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Immunoregulatory gene GIMAP6 suppresses lethal atherosclerotic vasculopathy and ischemic heart failure

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  DOI: 10.1016/j.cell.2026.09.032
  
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sciencedirect.com/science/article/pii/S0092867426011347
Sep 2026
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Functional matrix vesicle replacement partially restores chemo-mechanical coupling in the aged bone niche

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  DOI: 10.1016/j.xcrm.2026.102923
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13522752/
Aug 2026
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Targeting host lipogenesis with a diarylamide inhibitor disrupts SARS-CoV-2 replication

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1. scibot 08 Aug 2026
  
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  DOI: 10.1016/j.isci.2026.117111
  
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sciencedirect.com/science/article/pii/S2589004226024892
Jul 2026
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Microbial metabolite hyodeoxycholic acid induces macrophage immunometabolic reprogramming and alleviates ulcerative colitis

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sciencedirect.com/science/article/pii/S2211124726008144
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GLP-1 regulates osteo-adipogenic fate of BMSCs via HIF-2-AKT signaling and supports trabecular bone in glucocorticoid-induced osteoporosis

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  DOI: 10.1016/j.stemcr.2026.103008
  
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sciencedirect.com/science/article/pii/S2213671126002195
Jun 2026
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FABP4 interacts with PPARγ to promote malignant progression in pancreatic cancer

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sciencedirect.com/science/article/pii/S258900422601922X
May 2026
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Calcium influx drives m6A-dependent RUNX1T1 splicing to promote adipogenic commitment

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1. scibot 29 May 2026
  
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  DOI: 10.1016/j.celrep.2026.117471
  
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sciencedirect.com/science/article/pii/S2211124726005498
Apr 2026
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Intestinal dysbiosis exacerbates skin inflammation via microbial metabolite-driven Th2 cell differentiation

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  DOI: 10.1016/j.immuni.2026.03.019
  
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sciencedirect.com/science/article/pii/S1074761326001305
Jan 2026
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Impaired VLCFA-peroxisome-mediated intestinal epithelial repair causes gastrointestinal sequelae of long COVID

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1. scibot 05 Jan 2026
  
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  DOI: 10.1016/j.devcel.2025.12.003
  
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sciencedirect.com/science/article/pii/S1534580725007476
Sep 2025
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Gut symbiont-derived ursodeoxycholic acid promotes fatty acid oxidation to protect against renal ischemia-reperfusion injury

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1. scibot 27 Sep 2025
  
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  DOI: 10.1016/j.xcrm.2025.102373
  
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sciencedirect.com/science/article/pii/S266637912500446X
May 2025
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BPS Publications

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1. scibot 20 May 2025
  
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  DOI: 10.1111/bph.70045
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70045
Mar 2025
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Adhesion strength of tumor cells predicts metastatic disease in vivo

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1. scibot 06 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115359
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12014391/
Dec 2024
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Anti-b diminishes hyperlipidaemia and hepatic steatosis in hamsters and mice by suppressing the mTOR/PPARγ and mTOR/SREBP1 signalling pathways

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1. scibot 05 Dec 2024
  
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  DOI: 10.1111/bph.17397
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.17397
Sep 2024
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m6A mRNA methylation in brown fat regulates systemic insulin sensitivity via an inter-organ prostaglandin signaling axis independent of UCP1

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1. scibot 10 Sep 2024
  
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  DOI: 10.1016/j.cmet.2024.08.006
  
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sciencedirect.com/science/article/pii/S1550413124003334
Jul 2024
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Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration

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1. scibot 24 Jul 2024
  
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sciencedirect.com/science/article/pii/S1534580724003988
May 2024
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BPS Publications

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1. scibot 25 May 2024
  
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  DOI: 10.1111/bph.16306
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16306
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The myokine CCL5 recruits subcutaneous preadipocytes and promotes intramuscular fat deposition in obese mice

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1. scibot 24 May 2024
  
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  DOI: 10.1152/ajpcell.00591.2023
  
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52.53.155.43/d3a149c44aa79cb46ab8be6ffb877d3c928909cb/yu-et-al-2024-the-myokine-ccl5-recruits-subcutaneous-preadipocytes-and-promotes-intramuscular-fat-deposition-in-obese-html.html
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BPS Publications

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1. scibot 03 May 2024
  
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  DOI: 10.1111/bph.16360
  
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bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16360
Mar 2024
52.53.155.43 52.53.155.43

Inhibiting sEH suppresses NF-κB p65 signaling and reduces CXCL10 expression as a potential therapeutic target in HT

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  DOI: 10.1210/clinem/dgae163
  
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52.53.155.43/dd0b2fe053939845b97e0d2ac9f7087ec962b0c8/dgae163-html.html
Feb 2024
www.nature.com www.nature.com

Molecular mechanism underlying miR-204-5p regulation of adipose-derived stem cells differentiation into cells from three germ layers

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  DOI: 10.1038/s41420-024-01852-4
  
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nature.com/articles/s41420-024-01852-4
Nov 2023
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TET2 is recruited by CREB to promote Cebpb, Cebpa and Pparg transcription by facilitating hydroxymethylation during adipocyte differentiation

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  DOI: 10.1016/j.isci.2023.108312
  
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sciencedirect.com/science/article/pii/S2589004223023891
Oct 2023
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WTAP boosts lipid oxidation and induces diabetic cardiac fibrosis by enhancing AR methylation

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  DOI: 10.1016/j.isci.2023.107931
  
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sciencedirect.com/science/article/pii/S2589004223020084
Aug 2023
52.53.155.43 52.53.155.43

LncRNA DGCR5-encoded polypeptide RIP aggravates SONFH by repressing nuclear localization of β-catenin in BMSCs

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112969
  
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2. scibot 16 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112969
  
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52.53.155.43/65d236bbeb2359d9c37ad7ca2311e1cf29f548cc/PIIS2211124723009804-html.html
Mar 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Suppression of preadipocyte determination by SOX4 limits white adipocyte hyperplasia in obesity

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1. scibot 24 Mar 2023
  
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  DOI: 10.1016/j.isci.2023.106289
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10030912/
Mar 2022
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Selective modulator of nuclear receptor PPARγ with reduced adipogenic potential ameliorates experimental nephrotic syndrome

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  DOI: 10.1016/j.isci.2022.104001
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8927998/
Aug 2021
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Isovitexin-Mediated Regulation of Microglial Polarization in Lipopolysaccharide-Induced Neuroinflammation via Activation of the CaMKKβ/AMPK-PGC-1α Signaling Axis

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1. scibot 06 Aug 2021
  
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  DOI: 10.3389/fimmu.2019.02650
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6868066/
Jul 2021
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Pharmaceutical targeting of succinate dehydrogenase in fibroblasts controls bleomycin-induced lung fibrosis

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1. scibot 30 Jul 2021
  
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  DOI: 10.1016/j.redox.2021.102082
  
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sciencedirect.com/science/article/pii/S221323172100241X
Sep 2020
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Shared PPARα/γ Target Genes Regulate Brown Adipocyte Thermogenic Function

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1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.02.032
  
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sciencedirect.com/science/article/pii/S2211124720301935
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BPS Publications

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1. scibot 14 Sep 2020
  
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  RRID:AB_10596794
  
  DOI: 10.1111/bph.14886
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14886