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  1. Last 7 days
  2. rupress.org rupress.org
    Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization
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    1. scibot 25 Apr 2024
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      DOI: 10.1083/jcb.202307026

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      DOI: 10.1083/jcb.202307026

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    rupress.org/jcb/article/223/4/e202307026/276570/Tunable-DNMT1-degradation-reveals-DNMT1-DNMT3B
  3. Feb 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pim kinase inhibitors increase gilteritinib cytotoxicity in FLT3-ITD acute myeloid leukemia through GSK-3β activation and c-Myc and Mcl-1 proteasomal degradation
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    1. scibot 21 Feb 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10870818/
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    Specialized replication mechanisms maintain genome stability at human centromeres
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    1. scibot 15 Feb 2024
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    2. scibot 15 Feb 2024
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    sciencedirect.com/science/article/pii/S1097276524000546
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    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
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    1. scibot 13 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001062
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    CRISPR/Cas9 mediated Y-chromosome elimination affects human cells transcriptome
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    1. scibot 02 Feb 2024
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      DOI: 10.1186/s13578-024-01198-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10829266/
  8. Nov 2023
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    K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution
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    1. scibot 28 Nov 2023
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    sciencedirect.com/science/article/pii/S1097276523008481
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    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
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    1. scibot 13 Nov 2023
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    sciencedirect.com/science/article/pii/S1097276521001787
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    Membrane anchoring of the DIRAS3 N-terminal extension permits tumor suppressor function
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      DOI: 10.1016/j.isci.2023.108151

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    sciencedirect.com/science/article/pii/S2589004223022289
  12. Oct 2023
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    GLUT-1 changes in paediatric Huntington disease brain cortex and fibroblasts: an observational case-control study
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    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.ebiom.2023.104849

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    sciencedirect.com/science/article/pii/S2352396423004152
  14. Aug 2023
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    L858R emerges as a potential biomarker predicting response of lung cancer models to anti-EGFR antibodies: Comparison of osimertinib vs. cetuximab
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    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101142

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    2. scibot 10 Aug 2023
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      DOI: 10.1016/j.xcrm.2023.101142

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  16. Jul 2023
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    FUBP1 is a general splicing factor facilitating 3′ splice site recognition and splicing of long introns
    1
    1. scibot 28 Jul 2023
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      DOI: 10.1016/j.molcel.2023.07.002

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    sciencedirect.com/science/article/pii/S1097276523005166
  18. Apr 2023
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    Ablation of palladin in adult heart causes dilated cardiomyopathy associated with intercalated disc abnormalities
    1
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      DOI: 10.7554/eLife.78629

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    ncbi.nlm.nih.gov/pmc/articles/PMC10069870/
  20. Feb 2023
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    PIMT regulates Hepatic Gluconeogenesis in Mice
    1
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    sciencedirect.com/science/article/pii/S2589004223001979
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    DDX47, MeCP2, and other functionally heterogeneous factors protect cells from harmful R loops
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      DOI: 10.1016/j.celrep.2023.112148

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    sciencedirect.com/science/article/pii/S2211124723001596
  23. Nov 2022
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    BPS Publications
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    1. scibot 20 Nov 2022
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      DOI: 10.1111/bph.15971

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15971
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    Architecture of the outbred brown fat proteome defines regulators of metabolic physiology
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    1. scibot 11 Nov 2022
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      DOI: 10.1016/j.cell.2022.10.003

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    sciencedirect.com/science/article/pii/S0092867422013186
  26. Oct 2022
  27. www.sciencedirect.com www.sciencedirect.com
    Competition for endothelial cell polarity drives vascular morphogenesis in the mouse retina
    2
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      DOI: 10.1016/j.devcel.2022.09.002

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    2. scibot 11 Oct 2022
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      DOI: 10.1016/j.devcel.2022.09.002

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    sciencedirect.com/science/article/pii/S1534580722006323
  28. Aug 2022
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    Sonic hedgehog is not a limb morphogen but acts as a trigger to specify all digits in mice
    1
    1. scibot 17 Aug 2022
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      DOI: 10.1016/j.devcel.2022.07.016

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    sciencedirect.com/science/article/pii/S1534580722005470
  30. Mar 2022
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    CENP-B-mediated DNA loops regulate activity and stability of human centromeres
    1
    1. scibot 26 Mar 2022
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      DOI: 10.1016/j.molcel.2022.02.032

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    sciencedirect.com/science/article/pii/S1097276522002064
  32. Dec 2021
  33. www.sciencedirect.com www.sciencedirect.com
    Cysteine 253 of UCP1 regulates energy expenditure and sex-dependent adipose tissue inflammation
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    sciencedirect.com/science/article/pii/S1550413121005313
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glutamine deprivation triggers NAGK-dependent hexosamine salvage
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      DOI: 10.7554/eLife.62644

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    ncbi.nlm.nih.gov/pmc/articles/PMC8631944/
  35. Nov 2021
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myopalladin knockout mice develop cardiac dilation and show a maladaptive response to mechanical pressure overload
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC8547954/
  37. www.sciencedirect.com www.sciencedirect.com
    Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-AK124ub
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    sciencedirect.com/science/article/pii/S2211124721013978
  38. Oct 2021
  39. www.sciencedirect.com www.sciencedirect.com
    Inhibition of HIV infection by structural proteins of the inner nuclear membrane is associated with reduced chromatin dynamics
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    sciencedirect.com/science/article/pii/S2211124721012171
  40. Sep 2021
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Establishment and genetic characterization of cell lines derived from proliferating nasal polyps and sinonasal inverted papillomas
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      DOI: 10.1038/s41598-021-96444-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC8384845/
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    Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome
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    sciencedirect.com/science/article/pii/S2211124721010354
  43. Aug 2021
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    Gain-of-function p53R172H mutation drives accumulation of neutrophils in pancreatic tumors, promoting resistance to immunotherapy
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    sciencedirect.com/science/article/pii/S2211124721010123
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.celrep.2019.01.105

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    ncbi.nlm.nih.gov/pmc/articles/PMC6391843/
  46. Jul 2021
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    Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity
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    sciencedirect.com/science/article/pii/S0960982219309327
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    cell.com/cell/abstract/S0092-8674(17)31064-4
  49. Jun 2021
  50. www.sciencedirect.com www.sciencedirect.com
    NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma
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    sciencedirect.com/science/article/pii/S2211124721005970
  51. May 2021
  52. www.cell.com www.cell.com
    Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
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    cell.com/current-biology/abstract/S0960-9822(21)00287-6
  53. Apr 2021
  54. www.sciencedirect.com www.sciencedirect.com
    Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells
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      DOI: 10.1016/j.stem.2021.03.005

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    sciencedirect.com/science/article/pii/S1934590921001119
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    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
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      DOI: 10.1016/j.ccell.2020.07.008

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    sciencedirect.com/science/article/pii/S153561082030369X
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    mTORC1 promotes cell growth via m6A-dependent mRNA degradation
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    sciencedirect.com/science/article/pii/S1097276521001787
  57. Mar 2021
  58. www.sciencedirect.com www.sciencedirect.com
    MMB-FOXM1-driven premature mitosis is required for CHK1 inhibitor sensitivity
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      DOI: 10.1016/j.celrep.2021.108808

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    sciencedirect.com/science/article/pii/S2211124721001224
  59. Nov 2020
  60. www.sciencedirect.com www.sciencedirect.com
    Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum
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  61. Oct 2020
  62. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Androgen Receptor signaling promotes the neural progenitor cell pool in the developing cortex
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      DOI: 10.1111/jnc.15192

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  63. Sep 2020
  64. www.sciencedirect.com www.sciencedirect.com
    A Comprehensive Map of the Monocyte-Derived Dendritic Cell Transcriptional Network Engaged upon Innate Sensing of HIV
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      DOI: 10.1016/j.celrep.2019.12.054

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  65. www.sciencedirect.com www.sciencedirect.com
    Loss of Thymine DNA Glycosylase Causes Dysregulation of Bile Acid Homeostasis and Hepatocellular Carcinoma
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      DOI: 10.1016/j.celrep.2020.03.039

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  66. www.sciencedirect.com www.sciencedirect.com
    Assembly of Peripheral Actomyosin Bundles in Epithelial Cells Is Dependent on the CaMKK2/AMPK Pathway
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      DOI: 10.1016/j.celrep.2020.02.096

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  67. Jan 2020
  68. elifesciences.org elifesciences.org
    Non-canonical Wnt signaling regulates junctional mechanocoupling during angiogenic collective cell migration
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      DOI: 10.7554/eLife.45853

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  69. www.sciencedirect.com www.sciencedirect.com
    Depletion of the MFAP1/SPP381 Splicing Factor Causes R-Loop-Independent Genome Instability
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      DOI: 10.1016/j.celrep.2019.07.010

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  70. www.sciencedirect.com www.sciencedirect.com
    Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization
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      DOI: 10.1016/j.ccell.2019.08.006

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  71. www.sciencedirect.com www.sciencedirect.com
    Centromere Dysfunction Compromises Mitotic Spindle Pole Integrity
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      DOI: 10.1016/j.cub.2019.07.052

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  72. www.sciencedirect.com www.sciencedirect.com
    Oncogenic Mutations Rewire Signaling Pathways by Switching Protein Recruitment to Phosphotyrosine Sites
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      DOI: 10.1016/j.cell.2019.09.008

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  73. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.celrep.2019.01.106

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  74. www.sciencedirect.com www.sciencedirect.com
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  75. Nov 2018
  76. www.sciencedirect.com www.sciencedirect.com
    NONO Detects the Nuclear HIV Capsid to Promote cGAS-Mediated Innate Immune Activation
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  77. www.sciencedirect.com www.sciencedirect.com
    mTORC1 Promotes Metabolic Reprogramming by the Suppression of GSK3-Dependent Foxk1 Phosphorylation
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  78. www.sciencedirect.com www.sciencedirect.com
    Crosstalk between KCNK3-Mediated Ion Current and Adrenergic Signaling Regulates Adipose Thermogenesis and Obesity
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  79. Nov 2017
  80. www.sciencedirect.com www.sciencedirect.com
    Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition
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      Curator: @chewbeccax

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  81. www.sciencedirect.com www.sciencedirect.com
    Centriolar Satellites Control GABARAP Ubiquitination and GABARAP-Mediated Autophagy
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  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sam68 promotes self-renewal and glycolytic metabolism in mouse neural progenitor cells by modulating Aldh1a3 pre-mRNA 3'-end processing
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