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Cuproptosis-immunity crosstalk informs strategy to overcome immunotherapy resistance

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1. scibot 25 Jun 2026
  
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  DOI: 10.1016/j.cell.2026.05.036
  
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sciencedirect.com/science/article/pii/S0092867426006367
Jun 2026
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Hypoxia shapes both therapeutic response and resistance in metastatic clear cell renal cell carcinoma

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  DOI: 10.1016/j.ccell.2026.05.007
  
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sciencedirect.com/science/article/pii/S1535610826002527
May 2026
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Targeting ADAR1 p150 triggers tumor inhibition and antitumor immunity to overcome immunotherapy resistance

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1. scibot 22 May 2026
  
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  DOI: 10.1016/j.isci.2026.115978
  
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sciencedirect.com/science/article/pii/S2589004226013532
Apr 2026
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Sulfur partitioning from cysteine controls T cell proliferation and effector function

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  DOI: 10.1016/j.cell.2026.03.012
  
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sciencedirect.com/science/article/pii/S0092867426002795
Mar 2026
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p16High-expressing immune cells control disease tolerance as a defense and health span-extending strategy

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1. scibot 27 Mar 2026
  
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  DOI: 10.1016/j.immuni.2026.02.013
  
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sciencedirect.com/science/article/pii/S107476132600083X
Jan 2026
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e013832.full-html.html

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  DOI: 10.1136/jitc-2025-013832
  
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54.241.53.176/ca60c4c2a1e906c1762fed2c822dc77ccf0438f0/e013832.full-html.html
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Depletion of myeloid cells in AG129 mice reduces the infection-mediated oxidative stress and restrains dengue virus-induced thymic atrophy

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1. scibot 16 Jan 2026
  
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  DOI: 10.1186/s12964-025-02572-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12797958/
Dec 2025
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RAS(ON) multi-selective inhibition drives antitumor immunity in preclinical models of NRAS-mutant melanoma

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1. scibot 03 Dec 2025
  
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  DOI: 10.1158/2326-6066.CIR-25-0744
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12666865/
Nov 2025
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GM-CSF and specific type 2 cytokines induce CD103+ and CD301b+ cell states in cDC1s and cDC2s

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1. scibot 29 Nov 2025
  
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  DOI: 10.1016/j.celrep.2025.116589
  
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sciencedirect.com:5037/science/article/pii/S2211124725013610
Jul 2025
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Structure of gut microbial glycolipid modulates host inflammatory response

1
1. scibot 23 Jul 2025
  
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  DOI: 10.1016/j.cell.2025.05.016
  
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sciencedirect.com/science/article/pii/S0092867425005665
Jun 2025
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EZH2 loss during metabolic stress drives restoration of MHC class I machinery in melanoma

1
1. scibot 12 Jun 2025
  
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  DOI: 10.1016/j.isci.2025.112750
  
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sciencedirect.com/science/article/pii/S2589004225010119
Apr 2025
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Targeting the dendritic cell-secreted immunoregulatory cytokine CCL22 alleviates radioresistance

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1. scibot 02 Apr 2025
  
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  DOI: 10.1158/1078-0432.CCR-23-3616
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11444901/
Mar 2025
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Inflammatory cytokines mediate the induction of and awakening from metastatic dormancy

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1. scibot 04 Mar 2025
  
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  RRID:AB_10612741
  
  DOI: 10.1016/j.celrep.2025.115388
  
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sciencedirect.com/science/article/pii/S2211124725001597
Dec 2024
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Inhibiting intracellular CD28 in cancer cells enhances antitumor immunity and overcomes anti-PD-1 resistance via targeting PD-L1

1
1. scibot 14 Dec 2024
  
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  DOI: 10.1016/j.ccell.2024.11.008
  
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sciencedirect.com/science/article/pii/S1535610824004434
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IL-17A/CEBPβ/OPN/LYVE-1 axis inhibits anti-tumor immunity by promoting tumor-associated tissue-resident macrophages

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1. scibot 12 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.115039
  
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sciencedirect.com/science/article/pii/S2211124724013901
May 2024
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CXCL16-dependent scavenging of oxidized lipids by islet macrophages promotes differentiation of pathogenic CD8+ T cells in diabetic autoimmunity

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1. scibot 16 May 2024
  
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  RRID:AB_10612741
  
  DOI: 10.1016/j.immuni.2024.04.017
  
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sciencedirect.com/science/article/pii/S107476132400222X
Apr 2024
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IFNα-induced BST2+ tumor-associated macrophages facilitate immunosuppression and tumor growth in pancreatic cancer by ERK-CXCL7 signaling

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1. scibot 11 Apr 2024
  
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  DOI: 10.1016/j.celrep.2024.114088
  
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sciencedirect.com/science/article/pii/S2211124724004169
Mar 2024
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Altered DNA methylation underlies monocyte dysregulation and immune exhaustion memory in sepsis

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1. scibot 05 Mar 2024
  
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  RRID:AB_10612741
  
  DOI: 10.1016/j.celrep.2024.113894
  
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sciencedirect.com/science/article/pii/S2211124724002225
Feb 2024
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Alleviation of monocyte exhaustion by BCG derivative mycolic acid

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1. scibot 08 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.108978
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10845070/
Jan 2024
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Tumor cell–intrinsic PD-1 promotes Merkel cell carcinoma growth by activating downstream mTOR-mitochondrial ROS signaling

2
1. scibot 25 Jan 2024
  
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  DOI: 10.1126/sciadv.adi2012
  
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  DOI: 10.1126/sciadv.adi2012
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10798567/
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Lymph node and tumor-associated PD-L1+ macrophages antagonize dendritic cell vaccines by suppressing CD8+ T cells

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1. scibot 19 Jan 2024
  
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  DOI: 10.1016/j.xcrm.2023.101377
  
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sciencedirect.com/science/article/pii/S2666379123006067
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Interferon-stimulated neutrophils as a predictor of immunotherapy response

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1. scibot 09 Jan 2024
  
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  DOI: 10.1016/j.ccell.2023.12.005
  
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sciencedirect.com/science/article/pii/S1535610823004336
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Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

2
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  DOI: 10.1016/j.devcel.2023.07.025
  
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  DOI: 10.1016/j.devcel.2023.07.025
  
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sciencedirect.com/science/article/pii/S1534580723003945
Oct 2023
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High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma

1
1. scibot 14 Oct 2023
  
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  DOI: 10.1016/j.xcrm.2023.101214
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10591052/
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Genetic and pharmaceutical targeting of HIF1α allows combo-immunotherapy to boost graft vs. leukemia without exacerbation graft vs. host disease

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1. scibot 13 Oct 2023
  
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  DOI: 10.1016/j.xcrm.2023.101236
  
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sciencedirect.com/science/article/pii/S2666379123004135
Mar 2023
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Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment

1
1. scibot 16 Mar 2023
  
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  DOI: 10.1016/j.ccell.2023.02.005
  
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sciencedirect.com/science/article/pii/S1535610823000338
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IFNγ is a central node of cancer immune equilibrium

1
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  DOI: 10.1016/j.celrep.2023.112219
  
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sciencedirect.com/science/article/pii/S2211124723002309
Feb 2023
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HRS regulates small extracellular vesicle PD-L1 secretion and is associated with anti-PD-1 treatment efficacy

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1. scibot 17 Feb 2023
  
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  DOI: 10.1158/2326-6066.CIR-22-0277
  
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aacrjournals.org/cancerimmunolres/article/11/2/228/716209/HRS-Regulates-Small-Extracellular-Vesicle-PD-L1
Jan 2023
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Lymphatic PD-L1 Expression Restricts Tumor-Specific CD8+ T-cell Responses

1
1. scibot 12 Jan 2023
  
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  DOI: 10.1158/0008-5472.CAN-21-0633
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9398148/
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Enhancing PD-L1 Degradation by ITCH during MAPK Inhibitor Therapy Suppresses Acquired Resistance

1
1. scibot 11 Jan 2023
  
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  DOI: 10.1158/2159-8290.CD-21-1463
  
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aacrjournals.org/cancerdiscovery/article/12/8/1942/707227/Enhancing-PD-L1-Degradation-by-ITCH-during-MAPK
Jun 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The SETDB1–TRIM28 complex suppresses antitumor immunity

1
1. scibot 07 Jun 2022
  
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  DOI: 10.1158/2326-6066.CIR-21-0754
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8647838/
Apr 2022
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Meflin-positive cancer-associated fibroblasts enhance tumor response to immune checkpoint blockade

1
1. scibot 08 Apr 2022
  
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  DOI: 10.26508/lsa.202101230
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8897596/
Dec 2021
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Stem-like intestinal Th17 cells give rise to pathogenic effector T cells during autoimmunity

1
1. scibot 07 Dec 2021
  
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  RRID:AB_10612741
  
  DOI: 10.1016/j.cell.2021.11.018
  
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sciencedirect.com/science/article/pii/S0092867421013337
Sep 2021
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Tumor-derived exosomes drive immunosuppressive macrophages in a pre-metastatic niche through glycolytic dominant metabolic reprogramming

1
1. scibot 24 Sep 2021
  
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  RRID:AB_10612741
  
  DOI: 10.1016/j.cmet.2021.09.002
  
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sciencedirect.com:5037/science/article/pii/S1550413121004216
Aug 2021
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Targeting Pin1 renders pancreatic cancer eradicable by synergizing with immunochemotherapy

1
1. scibot 16 Aug 2021
  
  in Public
  
  RRID:AB_10612741
  
  DOI: 10.1016/j.cell.2021.07.020
  
  Resource: (BioLegend Cat# 124312, RRID:AB_10612741)
  
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sciencedirect.com/science/article/pii/S0092867421008795
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The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

1
1. scibot 15 Aug 2021
  
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  RRID:AB_10612741
  
  DOI: 10.1016/j.ccell.2021.07.007
  
  Resource: (BioLegend Cat# 124312, RRID:AB_10612741)
  
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sciencedirect.com/science/article/pii/S1535610821003846
Sep 2020
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Single-Cell RNA Sequencing Reveals a Dynamic Stromal Niche That Supports Tumor Growth

1
1. scibot 16 Sep 2020
  
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  RRID:AB_10612741
  
  DOI: 10.1016/j.celrep.2020.107628
  
  Resource: (BioLegend Cat# 124312, RRID:AB_10612741)
  
  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:AB_10612741
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sciencedirect.com/science/article/pii/S2211124720305817
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The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection

1
1. scibot 14 Sep 2020
  
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  RRID:AB_10612741
  
  DOI: 10.1016/j.celrep.2020.107827
  
  Resource: (BioLegend Cat# 124312, RRID:AB_10612741)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S2211124720308081
Jan 2020
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STAT3 Activation-Induced Fatty Acid Oxidation in CD8+ T Effector Cells Is Critical for Obesity-Promoted Breast Tumor Growth

1
1. scibot 13 Jan 2020
  
  in Public
  
  RRID:AB_10612741
  
  DOI: 10.1016/j.cmet.2019.10.013
  
  Resource: (BioLegend Cat# 124312, RRID:AB_10612741)
  
  Curator: @ethanbadger
  
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cell.com/cell-metabolism/fulltext/S1550-4131(19)30604-7
Nov 2017
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Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy

1
1. scibot 08 Nov 2017
  
  in Public
  
  RRID:AB_10612741
  
  Curator: @Jmenke
  
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  SciCrunch record: RRID:AB_10612741
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_10612741 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610817303471