563 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    DNA-PK and ATM drive phosphorylation signatures that antagonistically regulate cytokine responses to herpesvirus infection or DNA damage
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    1. scibot 12 Apr 2024
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    sciencedirect.com/science/article/pii/S2405471224000887
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    Heterogeneity of tethered agonist signaling in adhesion G protein-coupled receptors
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    sciencedirect.com/science/article/pii/S245194562400120X
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    Chemically engineered mTOR-nanoparticle blockers enhance antitumour efficacy
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    1. scibot 11 Apr 2024
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    sciencedirect.com/science/article/pii/S2352396424001348
  5. 52.53.155.43 52.53.155.43
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    1. scibot 11 Apr 2024
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    Insulin receptor signaling engages bladder urothelial defenses that limit urinary tract infection
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    1. scibot 11 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724003358
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    Bacterial muropeptides promote OXPHOS and suppress mitochondrial stress in mammals
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    1. scibot 09 Apr 2024
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    sciencedirect.com/science/article/pii/S2211124724003954
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    Truncating NFKB1 variants cause combined NLRP3 inflammasome activation and type I interferon signaling and predispose to necrotizing fasciitis
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    1. scibot 09 Apr 2024
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    sciencedirect.com/science/article/pii/S2666379124001721
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    Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum
    1
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    sciencedirect.com/science/article/pii/S1534580724001801
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    Temporal dynamics and stoichiometry in human Notch signaling from Notch synaptic complex formation to nuclear entry of the Notch intracellular domain
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    sciencedirect.com/science/article/pii/S1534580724001898
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sexual Dimorphism of Circadian Liver Transcriptome.
    1
    1. scibot 03 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10973666/
  12. Mar 2024
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RNA binding proteins LARP4A and LARP4B promote sarcoma and carcinoma growth and metastasis
    1
    1. scibot 28 Mar 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10963253/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lupenone improves motor dysfunction in spinal cord injury mice through inhibiting the inflammasome activation and pyroptosis in microglia via the nuclear factor kappa B pathway
    1
    1. scibot 27 Mar 2024
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      DOI: 10.4103/1673-5374.389302

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  15. www.nature.com www.nature.com
    Light-mediated intracellular polymerization
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    1. scibot 26 Mar 2024
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      DOI: 10.1038/s41596-024-00970-8

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    nature.com/articles/s41596-024-00970-8
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    Angiotensin II type-2 receptor signaling facilitates liver injury repair and regeneration via inactivation of Hippo pathway
    1
    1. scibot 20 Mar 2024
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    Metabolic reprogramming of cancer cells by JMJD6-mediated pre-mRNA splicing associated with therapeutic response to splicing inhibitor
    1
    1. scibot 17 Mar 2024
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      DOI: 10.7554/eLife.90993

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    ncbi.nlm.nih.gov/pmc/articles/PMC10942784/
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    Housekeeping U1 snRNA facilitates antiviral innate immunity by promoting TRIM25-mediated RIG-I activation
    1
    1. scibot 15 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724002730
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    Combinatorial selective ER-phagy remodels the ER during neurogenesis
    1
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  20. 52.53.155.43 52.53.155.43
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    1. scibot 06 Mar 2024
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      DOI: 10.3892/ijo.2023.5518

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      DOI: 10.3892/ijo.2023.5518

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    Hepatic Snai1 and Snai2 promote liver regeneration and suppress liver fibrosis in mice
    2
    1. scibot 06 Mar 2024
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      DOI: 10.1016/j.celrep.2024.113875

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    sciencedirect.com/science/article/pii/S2211124724002031
  22. Feb 2024
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PPM1G promotes cell proliferation via modulating mutant GOF p53 protein expression in hepatocellular carcinoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10879691/
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    Disruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety
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    sciencedirect.com/science/article/pii/S107476132400044X
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    Axon-derived PACSIN1 binds to the Schwann cell survival receptor, LRP1, and transactivates TrkC to promote gliatrophic activities
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    onlinelibrary.wiley.com/doi/10.1002/glia.24510
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    Inhibition of mGluR5/PI3K-AKT Pathway Alleviates Alzheimer’s Disease-Like Pathology Through the Activation of Autophagy in 5XFAD Mice
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      DOI: 10.3233/JAD-221058

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    content.iospress.com/articles/journal-of-alzheimers-disease/jad221058
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    Sleep fragmentation induces heart failure in a hypertrophic cardiomyopathy mouse model by altering redox metabolism
    1
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    Signaling via a CD27-TRAF2-SHP-1 axis during naive T cell activation promotes memory-associated gene regulatory networks
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    Proline restores mitochondrial function and reverses aging hallmarks in senescent cells
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    sciencedirect.com/science/article/pii/S2211124724000664
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    Extracellular-vesicle-packaged S100A11 from osteosarcoma cells mediates lung premetastatic niche formation by recruiting gMDSCs
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    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
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    sciencedirect.com/science/article/pii/S1097276524000480
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    TRPM2 enhances ischemic excitotoxicity by associating with PKCγ
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  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
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    ncbi.nlm.nih.gov/pmc/articles/PMC10830871/
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    Subsets of interferon signaling predict response to immune checkpoint blockade in melanoma patients
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    Streptococcus anginosus promotes gastric inflammation, atrophy, and tumorigenesis in mice
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    sciencedirect.com/science/article/pii/S0092867424000060
  36. Jan 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning
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    ncbi.nlm.nih.gov/pmc/articles/PMC10800076/
  38. www.embopress.org www.embopress.org
    Zika virus depletes neural stem cells and evades selective autophagy by suppressing the Fanconi anemia protein FANCC
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      GAPDH

      DOI: 10.15252/embr.201949183

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    Sympathetic nerve-enteroendocrine L cell communication modulates GLP-1 release, brain glucose utilization, and cognitive function
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      DOI: 10.1016/j.neuron.2023.12.012

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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRIP1 involves the pathogenesis of multiple myeloma via dual-regulation of proteasome and autophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10825369/
  41. dx.doi.org dx.doi.org
    cwad087-html.html
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    TTBK1 and CK1 inhibitors restore TDP-43 pathology and avoid disease propagation in lymphoblast from Alzheimer’s disease patients
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    The miR-23-27-24 clusters drive lipid-associated macrophage proliferation in obese adipose tissue
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    A peroxiredoxin-P38 MAPK scaffold increases MAPK activity by MAP3K-independent mechanisms
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    MHC Class II is Induced by IFNγ and Follows Three Distinct Patterns of Expression in Colorectal Cancer Organoids
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    Inhalation of ACE2 as a therapeutic target on sex-bias differences in SARS-CoV-2 infection and variant of concern
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    The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway
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    Targeting CD36 determines nicotine derivative NNK-induced lung adenocarcinoma carcinogenesis
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    Clinically Defined Mutations in MEN1 Alter Its Tumor-suppressive Function Through Increased Menin Turnover
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    Cyclo (MQCNS) has the potential to treat ischemic stroke
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    Hexokinase 2-mediated gene expression via histone lactylation is required for hepatic stellate cell activation and liver fibrosis
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    MEF2A suppresses stress responses that trigger DDX41-dependent IFN production
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    Combinatorial selective ER-phagy remodels the ER during neurogenesis
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    Spermine is a natural suppressor of AR signaling in castration-resistant prostate cancer
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    Early developmental deletion of forebrain Ank2 causes seizure-related phenotypes by reshaping the synaptic proteome
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    IGF1R inhibition enhances the therapeutic effects of Gq/11 inhibition in metastatic uveal melanoma progression
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    Cytosolic LPS-induced caspase-11 oligomerization and activation is regulated by extended synaptotagmin 1
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    Generation of host-directed and virus-specific antivirals using targeted protein degradation promoted by small molecules and viral RNA mimics
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    Increased G3BP2-Tau interaction in tauopathies is a natural defense against Tau aggregation
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    An EZH2-NF-κB Regulatory Axis Drives Expression of Pro-Oncogenic Gene Signatures in Triple Negative Breast Cancer
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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    Endothelial MRs mediate Western diet-induced lipid disorders and skeletal muscle insulin resistance in females
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    Reprogramming of Iron Metabolism Confers Ferroptosis Resistance in ECM-Detached Cells
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    A nanotherapeutic strategy that engages cytotoxic and immunosuppressive activities for the treatment of cancer recurrence following organ transplantation
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    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
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    Mitoxantrone and Mitoxantrone-Loaded Iron Oxide Nanoparticles Induce Cell Death in Human Pancreatic Ductal Adenocarcinoma Cell Spheroids
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    Stem cell competition driven by the Axin2-p53 axis controls brain size during murine development
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    N,N-Dimethyl-3β-hydroxycholenamide attenuates neuronal death and retinal inflammation in retinal ischemia/reperfusion injury by inhibiting Ninjurin 1
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    Phosphate Depletion in Insulin-Insensitive Skeletal Muscle Drives AMPD Activation and Sarcopenia in Chronic Kidney DIsease
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    Neofunctionalisation of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes
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    Celastrol directly binds with VAMP7 and RAB7 to inhibit autophagy and induce apoptosis in preadipocytes
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    Inhibiting tau protein improves the recovery of spinal cord ... : Neural Regeneration Research
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    Histone malonylation is regulated by SIRT5 and KAT2A
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    Phosphomimetics at Ser199/Ser202/Thr205 in Tau Impairs Axonal Transport in Rat Hippocampal Neurons
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    Coumarin-derived imino sulfonate 5h ameliorates cardiac injury induced by myocardial infarction via activating the Sirt1/Nrf2 signaling pathway
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    Aberrant serotonergic signaling contributes to the hyperexcitability of CA1 pyramidal neurons in a mouse model of Alzheimer’s disease
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    HRS regulates small extracellular vesicle PD-L1 secretion and is associated with anti-PD-1 treatment efficacy
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    HMGB1/GPC3 dual targeting vaccine induces dendritic cells-mediated CD8+T cell immune response and elicits potential therapeutic effect in hepatocellular carcinoma
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    CD70 is a therapeutic target upregulated in EMT-associated EGFR tyrosine kinase inhibitor resistance
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    Neuroprotective Effects of a Multi-Herbal Extract on Axonal and Synaptic Disruption in Vitro and Cognitive Impairment in Vivo
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    Asparagine and Glutamine Deprivation Alters Ionizing Radiation Response, Migration and Adhesion of a p53null Colorectal Cancer Cell Line
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    Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation
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      RRID:AB_10622025
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    sciencedirect.com/science/article/pii/S1550413122003515