86 Matching Annotations
  1. Aug 2024
  2. www.cell.com www.cell.com
    RIPK1 Promotes Energy Sensing by the mTORC1 Pathway
    1
    1. scibot 02 Aug 2024
      AMPK

      DOI: 10.1016/j.molcel.2020.11.008

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    cell.com/molecular-cell/fulltext/S1097-2765(20)30786-3
  3. Jul 2024
  4. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224017851-main-html.html
    1
    1. scibot 25 Jul 2024
      RRID:AB_10622186

      DOI: 10.1016/j.isci.2024.110560

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    52.53.155.43/28f1f0cd51770599356cfb72d036c0e468b38b34/1-s2.0-S2589004224017851-main-html.html
  5. www.sciencedirect.com www.sciencedirect.com
    Citrate metabolism controls the senescent microenvironment via the remodeling of pro-inflammatory enhancers
    1
    1. scibot 25 Jul 2024
      AB_10622186

      DOI: 10.1016/j.celrep.2024.114496

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    sciencedirect.com/science/article/pii/S2211124724008258
  6. May 2024
  7. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 03 May 2024
      RRID:AB_10622186

      DOI: 10.1111/bph.16391

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16391
  8. Apr 2024
  9. 52.53.155.43 52.53.155.43
    JNEUROSCI.1563-23.2024.full (1)-html.html
    1
    1. scibot 26 Apr 2024
      RRID:AB_10622186

      DOI: 10.1523/jneurosci.1563-23.2024

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    52.53.155.43/3d13c66ed91f2e0714f85e7c6a7de97c0df74a89/JNEUROSCI.1563-23.2024.full (1)-html.html
  10. www.embopress.org www.embopress.org
    PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
    2
    1. scibot 25 Apr 2024
      Cell signalingCat#5831;RRID:AB_10622186

      DOI: 10.1038/s44319-024-00110-z

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    2. scibot 18 Apr 2024
      RRID:AB_10622186

      DOI: 10.1038/s44319-024-00110-z

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    embopress.org/doi/full/10.1038/s44319-024-00110-z
  11. www.embopress.org www.embopress.org
    PRODH safeguards human naive pluripotency by limiting mitochondrial oxidative phosphorylation and reactive oxygen species production
    1
    1. scibot 25 Apr 2024
      RRID:AB_10622186

      DOI: 10.1038/s44319-024-00110-z

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    embopress.org/doi/10.1038/s44319-024-00110-z
  12. www.sciencedirect.com www.sciencedirect.com
    25-Hydroxycholesterol regulates lysosome AMP kinase activation and metabolic reprogramming to educate immunosuppressive macrophages
    1
    1. scibot 19 Apr 2024
      RRID:AB_10622186

      DOI: 10.1016/j.immuni.2024.03.021

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    sciencedirect.com/science/article/pii/S1074761324001420
  13. Mar 2024
  14. www.sciencedirect.com www.sciencedirect.com
    PKM2 diverts glycolytic flux in dependence on mitochondrial one-carbon cycle
    1
    1. scibot 01 Mar 2024
      RRID:AB_10622186

      DOI: 10.1016/j.celrep.2024.113868

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    sciencedirect.com/science/article/pii/S2211124724001967
  15. Jan 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Lysine acetyltransferase 6A maintains CD4+ T cell response via epigenetic reprogramming of glucose metabolism in autoimmunity
    1
    1. scibot 19 Jan 2024
      RRID:AB_10622186

      DOI: 10.1016/j.cmet.2023.12.016

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    sciencedirect.com/science/article/pii/S1550413123004679
  17. Dec 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin alleviates hepatic iron overload and ferroptosis through AMPK-ferroportin pathway in HFD-induced NAFLD
    1
    1. scibot 13 Dec 2023
      RRID:AB_10622186

      DOI: 10.1016/j.isci.2023.108560

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    ncbi.nlm.nih.gov/pmc/articles/PMC10711470/
  19. Nov 2023
  20. www.sciencedirect.com www.sciencedirect.com
    CD226 maintains regulatory T cell phenotype stability and metabolism by the mTOR/Myc pathway under inflammatory conditions
    1
    1. scibot 02 Nov 2023
      RRID:AB_10622186

      DOI: 10.1016/j.celrep.2023.113306

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    sciencedirect.com/science/article/pii/S2211124723013189
  21. Oct 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phosphorylated YBX2 is stabilized to promote glycolysis in brown adipocytes
    1
    1. scibot 20 Oct 2023
      RRID:AB_10622186

      DOI: 10.1016/j.isci.2023.108091

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    ncbi.nlm.nih.gov/pmc/articles/PMC10583057/
  23. Aug 2023
  24. 52.53.155.43 52.53.155.43
    Supplemental_Material.doc-html.html
    1
    1. scibot 10 Aug 2023
      RRID:AB_10622186

      DOI: 10.2337/db22-0745

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    52.53.155.43/f40c8204621797818d872b387b2c0141763e87fb/Supplemental_Material.doc-html.html
  25. Jul 2023
  26. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Chen - Anthelmintics nitazoxanide protects against experimental pulmonary fibrosis-html.html
    2
    1. scibot 21 Jul 2023
      RRID:AB_10622186

      DOI: 10.1111/bph.16190

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    2. scibot 21 Jul 2023
      RRID:AB_10622186

      DOI: 10.1111/bph.16190

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    52.53.155.43/01e7f498781407a431fc8d9b3b9cdd8be1437af6/British J Pharmacology - 2023 - Chen - Anthelmintics nitazoxanide protects against experimental pulmonary fibrosis-html.html
  27. Jun 2023
  28. www.jneurosci.org www.jneurosci.org
    Chronic neuronal inactivity utilizes the mTOR-TFEB pathway to drive transcription-dependent autophagy for homeostatic up-scaling
    1
    1. scibot 01 Jun 2023
      RRID:AB_10622186

      DOI: 10.1523/JNEUROSCI.0146-23.2023

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    jneurosci.org/content/43/15/2631
  29. Mar 2023
  30. www.sciencedirect.com www.sciencedirect.com
    TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy
    1
    1. scibot 22 Mar 2023
      RRID:AB_10622186

      DOI: 10.1016/j.jbc.2023.104621

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    sciencedirect.com/science/article/pii/S0021925823002636
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin Prevents Endothelial Oxidative Stress and Microvascular Insulin Resistance during Obesity Development in Male Rats
    1
    1. scibot 05 Mar 2023
      RRID:AB_10622186

      DOI: 10.1152/ajpendo.00240.2021

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    ncbi.nlm.nih.gov/pmc/articles/PMC8897003/
  32. Feb 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Correction: Dichotomous role of the human mitochondrial Na+/Ca2+/Li+ exchanger NCLX in colorectal cancer growth and metastasis
    1
    1. scibot 15 Feb 2023
      RRID:AB_10622186

      DOI: 10.7554/eLife.86471

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    ncbi.nlm.nih.gov/pmc/articles/PMC9910825/
  34. Dec 2022
  35. 52.53.155.43 52.53.155.43
    Skeletal muscle contraction kinetics and AMPK responses are modulated by the adenine nucleotide degrading enzyme AMPD1
    1
    1. scibot 01 Dec 2022
      AB_10622186

      DOI: 10.1152/japplphysiol.00035.2022

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    52.53.155.43/03be253bad6d0f5ac4ce904b191746cca4ce0f61/japplphysiol.00035.2022-html.html
  36. Nov 2022
  37. www.sciencedirect.com www.sciencedirect.com
    AMPK directly phosphorylates TBK1 to integrate glucose sensing into innate immunity
    1
    1. scibot 17 Nov 2022
      RRID:AB_10622186

      DOI: 10.1016/j.molcel.2022.10.026

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    sciencedirect.com/science/article/pii/S1097276522010541
  38. www.sciencedirect.com www.sciencedirect.com
    Energy sensor AMPK gamma regulates translation via phosphatase PPP6C independent of AMPK alpha
    1
    1. scibot 17 Nov 2022
      RRID:AB_10622186

      DOI: 10.1016/j.molcel.2022.10.030

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    sciencedirect.com/science/article/pii/S1097276522010589
  39. www.cell.com www.cell.com
    Downregulation of hepatic ceruloplasmin ameliorates NAFLD via SCO1-AMPK-LKB1 complex
    1
    1. scibot 10 Nov 2022
      RRID:AB_10622186

      DOI: 10.1016/j.celrep.2022.111498

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    cell.com/cell-reports/abstract/S2211-1247(22)01348-1
  40. Sep 2022
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hyperuricemia contributes to glucose intolerance of hepatic inflammatory macrophages and impairs the insulin signaling pathway via IRS2-proteasome degradation
    1
    1. scibot 30 Sep 2022
      RRID:AB_10622186

      DOI: 10.3389/fimmu.2022.931087

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    ncbi.nlm.nih.gov/pmc/articles/PMC9513153/
  42. Aug 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Activation of mitochondrial TRAP1 stimulates mitochondria-lysosome crosstalk and correction of lysosomal dysfunction
    1
    1. scibot 30 Aug 2022
      RRID:AB_10622186

      DOI: 10.1016/j.isci.2022.104941

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    sciencedirect.com/science/article/pii/S2589004222012135
  44. www.sciencedirect.com www.sciencedirect.com
    The AMPK-HOXB9-KRAS axis regulates lung adenocarcinoma growth in response to cellular energy alterations
    1
    1. scibot 26 Aug 2022
      RRID:AB_10622186

      DOI: 10.1016/j.celrep.2022.111210

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    sciencedirect.com/science/article/pii/S2211124722010270
  45. www.sciencedirect.com www.sciencedirect.com
    HOTAIR interacts with PRC2 complex regulating the regional preadipocyte transcriptome and human fat distribution
    1
    1. scibot 02 Aug 2022
      RRID:AB_10622186

      DOI: 10.1016/j.celrep.2022.111136

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    sciencedirect.com/science/article/pii/S2211124722009457
  46. Jul 2022
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Manipulating bovine granulosa cell energy metabolism limits inflammation
    1
    1. scibot 14 Jul 2022
      RRID: AB_10622186

      DOI: 10.1530/REP-20-0554

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    ncbi.nlm.nih.gov/pmc/articles/PMC9272410/
  48. Jun 2022
  49. www.sciencedirect.com www.sciencedirect.com
    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
    1
    1. scibot 25 Jun 2022
      RRID:AB_10622186

      DOI: 10.1016/j.molcel.2022.06.005

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    sciencedirect.com/science/article/pii/S109727652200541X
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Astilbin Activates the Reactive Oxidative Species/PPARγ Pathway to Suppress Effector CD4+ T Cell Activities via Direct Binding With Cytochrome P450 1B1
    1
    1. scibot 01 Jun 2022
      RRID:AB_10622186

      DOI: 10.3389/fphar.2022.848957

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    ncbi.nlm.nih.gov/pmc/articles/PMC9150850/
  51. May 2022
  52. www.sciencedirect.com www.sciencedirect.com
    The lactate receptor GPR81 mediates hepatic lipid metabolism and the therapeutic effect of metformin on experimental NAFLDs
    1
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      RRID:AB_10622186

      DOI: 10.1016/j.ejphar.2022.174959

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    sciencedirect.com/science/article/pii/S0014299922002205
  53. Jan 2022
  54. www.sciencedirect.com www.sciencedirect.com
    Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease
    1
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      RRID:AB_10622186

      DOI: 10.1016/j.isci.2021.103697

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    sciencedirect.com/science/article/pii/S2589004221016679
  55. www.sciencedirect.com www.sciencedirect.com
    Seipin localizes at endoplasmic-reticulum-mitochondria contact sites to control mitochondrial calcium import and metabolism in adipocytes
    1
    1. scibot 12 Jan 2022
      RRID:AB_10622186

      DOI: 10.1016/j.celrep.2021.110213

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    sciencedirect.com/science/article/pii/S2211124721017174
  56. Dec 2021
  57. www.nature.com www.nature.com
    GPR120 induces regulatory dendritic cells by inhibiting HK2-dependent glycolysis to alleviate fulminant hepatic failure
    1
    1. scibot 21 Dec 2021
      RRID: AB_10622186

      DOI: 10.1038/s41419-021-04394-0

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    nature.com/articles/s41419-021-04394-0
  58. reader.elsevier.com reader.elsevier.com
    Lysophosphatidic acid shifts metabolic and transcriptional landscapes to induce a distinct cellular state in human pluripotent stem cells
    1
    1. scibot 01 Dec 2021
      RRID:AB_10622186

      DOI: 10.1016/j.celrep.2021.110063

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    reader.elsevier.com/reader/sd/pii/S2211124721015497
  59. Oct 2021
  60. www.sciencedirect.com www.sciencedirect.com
    β2-adrenergic receptor signaling regulates metabolic pathways critical to myeloid-derived suppressor cell function within the TME
    1
    1. scibot 27 Oct 2021
      5831

      DOI: 10.1016/j.celrep.2021.109883

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    sciencedirect.com/science/article/pii/S221112472101353X
  61. Sep 2021
  62. academic.oup.com academic.oup.com
    Rosiglitazone requires hepatocyte PPARγ expression to promote steatosis in male mice with diet-induced obesity
    1
    1. scibot 30 Sep 2021
      RRID:AB_10622186

      DOI: 10.1210/endocr/bqab175

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    academic.oup.com/endo/article/162/11/bqab175/6356057
  63. www.sciencedirect.com www.sciencedirect.com
    DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation
    1
    1. scibot 22 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109739

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  64. Aug 2021
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  66. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  67. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  68. Jul 2021
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  70. www.cell.com www.cell.com
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    Protective role of GPR120 in the maintenance of pregnancy by promoting decidualization via regulation of glucose metabolism
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    An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stress
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  75. May 2021
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    Removal of epididymal visceral adipose tissue prevents obesity-induced multi-organ insulin resistance in male mice
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  79. Apr 2021
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    Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade
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    SETD2 Restricts Prostate Cancer Metastasis by Integrating EZH2 and AMPK Signaling Pathways
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  83. Mar 2021
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    The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity
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  85. Feb 2021
  86. www.nature.com www.nature.com
    Metabolic conditioning of CD8 + effector T cells for adoptive cell therapy
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  87. academic.oup.com academic.oup.com
    Myeloid-derived Growth Factor Promotes Intestinal Glucagon-like Peptide-1 Production in Male Mice with Type 2 Diabetes
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  88. Oct 2020
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SWELL1 regulates skeletal muscle cell size, intracellular signaling, adiposity and glucose metabolism
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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AMPK promotes SPOP-mediated NANOG degradation to regulate prostate cancer cell stemness
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  91. Sep 2020
  92. www.sciencedirect.com www.sciencedirect.com
    FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle
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  93. www.cell.com www.cell.com
    A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AMPK-dependent activation of the Cyclin Y/CDK16 complex controls autophagy
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  95. www.jbc.org www.jbc.org
    14-3-3 proteins protect AMPK-phosphorylated ten-eleven translocation-2 (TET2) from PP2A-mediated dephosphorylation
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      AMPKα

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  96. www.jbc.org www.jbc.org
    Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet–induced hepatic steatosis and insulin resistance by elevating IL-18 levels
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  97. journals.physiology.org journals.physiology.org
    Immobilization leads to alterations in intracellular phosphagen and creatine transporter content in human skeletal muscle | American Journal of Physiology-Cell Physiology
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      total AMPK

      DOI: 10.1152/ajpcell.00072.2020

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  98. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      anti‐rabbit AMPKα

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  99. Jan 2020
  100. elifesciences.org elifesciences.org
    PPM1H phosphatase counteracts LRRK2 signaling by selectively dephosphorylating Rab proteins
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      RRID:AB_10622186

      DOI: 10.7554/eLife.50416

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  101. www.sciencedirect.com www.sciencedirect.com
    SIRT6 Promotes Hepatic Beta-Oxidation via Activation of PPARα
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  102. www.sciencedirect.com www.sciencedirect.com
    Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses
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    Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies
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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  107. Nov 2018
  108. www.sciencedirect.com www.sciencedirect.com
    Metformin Promotes Antitumor Immunity via Endoplasmic-Reticulum-Associated Degradation of PD-L1
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    Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence
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    Acid Suspends the Circadian Clock in Hypoxia through Inhibition of mTOR
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  111. academic.oup.com academic.oup.com
    Bis-Indole–Derived NR4A1 Ligands and Metformin Exhibit NR4A1-Dependent Glucose Metabolism and Uptake in C2C12 Cells
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    The PLAG1-GDH1 Axis Promotes Anoikis Resistance and Tumor Metastasis through CamKK2-AMPK Signaling in LKB1-Deficient Lung Cancer
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    Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization
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      RRID:AB_10622186

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    sciencedirect.com/science/article/pii/S1074761317305332
  114. Nov 2017
  115. www.sciencedirect.com www.sciencedirect.com
    A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice
    1
    1. scibot 08 Nov 2017
      RRID:AB_10622186

      Curator: @Jmenke

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      RRID:AB_10622186 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1550413117304904
  116. www.sciencedirect.com www.sciencedirect.com
    Activation of Skeletal Muscle AMPK Promotes Glucose Disposal and Glucose Lowering in Non-human Primates and Mice
    1
    1. scibot 08 Nov 2017
      AB_10622186

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S1550413117302152
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    Nucleus-Translocated ACSS2 Promotes Gene Transcription for Lysosomal Biogenesis and Autophagy
    1
    1. scibot 08 Nov 2017
      AB_10622186

      Curator: @gabimpine

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  118. www.sciencedirect.com www.sciencedirect.com
    Global Reprogramming of Host Kinase Signaling in Response to Fungal Infection
    1
    1. scibot 08 Nov 2017
      AB_10622186

      Curator: @kaitlinsung

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      (Cell Signaling Technology Cat# 5831, RRID:AB_10622186)

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    sciencedirect.com/science/article/pii/S1931312817301543
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    DNA-PK Promotes the Mitochondrial, Metabolic, and Physical Decline that Occurs During Aging
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    1. scibot 08 Nov 2017
      AB_10622186

      Curator: @gabimpine

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    sciencedirect.com/science/article/pii/S1550413117302139
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    Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy
    1
    1. scibot 08 Nov 2017
      AB_10622186

      Curator: @chewbeccax

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      (Cell Signaling Technology Cat# 5831, RRID:AB_10622186)

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      RRID:AB_10622186 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276517300539