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Small-molecule activation of the tumor suppressor kinase LKB1 via the pseudokinase STRAD

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  DOI: 10.1016/j.chembiol.2026.07.013
  
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sciencedirect.com/science/article/abs/pii/S2451945626002862
Aug 2026
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FEBS Press

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  DOI: 10.1111/febs.70676
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.70676
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BPS Publications

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1. scibot 08 Aug 2026
  
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  DOI: 10.1111/bph.16268
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16268
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TGFβ-dependent upregulation of OCIAD2 is essential for epithelial-to-mesenchymal transition during mesendoderm differentiation

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sciencedirect.com/science/article/pii/S2213671126002365
Jun 2026
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Metabolic rewiring driven by phosphoglycolate phosphatase deletion inhibits ferroptosis

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  DOI: 10.1126/sciadv.aeb2368
  
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science.org/doi/10.1126/sciadv.aeb2368
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Metabolic rewiring driven by phosphoglycolate phosphatase deletion inhibits ferroptosis

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  DOI: 10.1126/sciadv.aeb2368
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13220862/
Apr 2026
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Graded activation of the CLEAR network through mTORC1 suppression on cargo-harboring lysosomes

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1. scibot 11 Apr 2026
  
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  DOI: 10.1016/j.celrep.2026.117228
  
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sciencedirect.com/science/article/pii/S2211124726003062
Mar 2026
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MC16 promotes mitochondrial biogenesis and ameliorates acute and diabetic nephropathy

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1. scibot 26 Mar 2026
  
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  DOI: 10.1111/bph.17440
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13011962/
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Targeting the energy metabolism of melanoma cells: FX-11 acts as a mitochondrial uncoupler

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1. scibot 26 Mar 2026
  
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  DOI: 10.1016/j.ejphar.2026.178800
  
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sciencedirect.com/science/article/pii/S0014299926002827
Feb 2026
54.241.53.176 54.241.53.176

1-s2.0-S2589004226003718-main-html.html

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54.241.53.176/f373af50e20ad2f683c3912e0dfb19a86e14ace7/1-s2.0-S2589004226003718-main-html.html
Jan 2026
54.241.53.176 54.241.53.176

bqag009-html.html

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1. scibot 23 Jan 2026
  
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  DOI: 10.1210/endocr/bqag009
  
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54.241.53.176/9f843a60575c776c468a5b7521b924f85ac7c8cf/bqag009-html.html
Oct 2025
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Glutamate decreases oxidative stress and lipid droplet formation in astrocytes

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1. scibot 23 Oct 2025
  
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  DOI: 10.1242/jcs.263983
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12539204/
Sep 2025
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The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity

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1. scibot 24 Sep 2025
  
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  DOI: 10.1016/j.molcel.2025.08.035
  
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sciencedirect.com/science/article/pii/S1097276525007415
Apr 2025
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Ursodeoxycholic acid prompts glycolytic dominance, reductive stress and epithelial-to-mesenchymal transition in ovarian cancer cells through NRF2 activation

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1. scibot 04 Apr 2025
  
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  DOI: 10.1038/s41420-025-02398-9
  
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link.springer.com/article/10.1038/s41420-025-02398-9
Mar 2025
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The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity

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1. scibot 23 Mar 2025
  
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  DOI: 10.1101/2025.02.17.638704
  
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biorxiv.org/content/10.1101/2025.02.17.638704v1
Dec 2024
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Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer

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1. scibot 03 Dec 2024
  
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  DOI: 10.1126/scisignal.adp1375
  
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science.org/doi/10.1126/scisignal.adp1375
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DEP-1 is a brain insulin receptor phosphatase that prevents the simultaneous activation of counteracting metabolic pathways

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1. scibot 02 Dec 2024
  
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  DOI: 10.1016/j.celrep.2024.114984
  
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sciencedirect.com/science/article/pii/S2211124724013354
Oct 2024
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Perfluoropentane-based oxygen-loaded nanodroplets reduce microglial activation through metabolic reprogramming

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1. scibot 02 Oct 2024
  
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  DOI: 10.4103/NRR.NRR-D-23-01299
  
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ncbi.nlm.nih.gov/pmc/articles/PMC11438333/
Aug 2024
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Propofol pretreatment inhibits ferroptosis and alleviates myocardial ischemia-reperfusion injury through the SLC16A13-AMPK-GPX4 pathway

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1. scibot 29 Aug 2024
  
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  DOI: 10.1016/j.biopha.2024.117345
  
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sciencedirect.com/science/article/pii/S0753332224012307
Jul 2024
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Pro-survival signaling regulates lipophagy essential for multiple myeloma resistance to stress-induced death

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1. scibot 18 Jul 2024
  
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  DOI: 10.1016/j.celrep.2024.114445
  
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sciencedirect.com/science/article/pii/S2211124724007745
May 2024
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Unraveling ETC complex I function in ferroptosis reveals a potential ferroptosis-inducing therapeutic strategy for LKB1-deficient cancers

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1. scibot 17 May 2024
  
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  DOI: 10.1016/j.molcel.2024.04.009
  
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sciencedirect.com/science/article/pii/S1097276524003241
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Tumor mitochondrial oxidative phosphorylation stimulated by the nuclear receptor RORγ represents an effective therapeutic opportunity in osteosarcoma

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  DOI: 10.1016/j.xcrm.2024.101519
  
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cell.com/cell-reports-medicine/fulltext/S2666-3791(24)00188-5
Feb 2024
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BPS Publications

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1. scibot 16 Feb 2024
  
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  DOI: 10.1111/bph.16283
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16283
Jan 2024
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O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK

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1. scibot 20 Jan 2024
  
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  DOI: 10.1016/j.isci.2023.108733
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10792243/
Aug 2023
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PIIS2589004223017029-html.html

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  DOI: 10.1016/j.isci.2023.107625
  
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52.53.155.43/258d74bd1c79cf4d725c254c0f9188b69c056c90/PIIS2589004223017029-html.html
Jul 2023
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Bexarotene improves motor function after spinal cord injury in mice

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1. scibot 22 Jul 2023
  
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  DOI: 10.4103/1673-5374.373676
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10358692/
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Fetal manipulation of maternal metabolism is a critical function of the imprinted Igf2 gene

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  DOI: 10.1016/j.cmet.2023.06.007
  
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cell.com/cell-metabolism/fulltext/S1550-4131(23)00217-6
May 2023
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ATROPHIC REMODELING OF THE HEART DURING VITAMIN D DEFICIENCY AND INSUFFICIENCY IN A RAT MODEL

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  DOI: 10.1016/j.jnutbio.2023.109382
  
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sciencedirect.com/science/article/pii/S0955286323001158
Dec 2022
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Inhibition of the LRRC8A channel promotes microglia/macrophage phagocytosis and improves outcomes after intracerebral hemorrhagic stroke

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  DOI: 10.1016/j.isci.2022.105527
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9708789/
Mar 2022
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Neurons undergo pathogenic metabolic reprogramming in models of familial ALS

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  DOI: 10.1016/j.molmet.2022.101468
  
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sciencedirect.com/science/article/pii/S2212877822000370
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Nicotinamide Breaks Effector CD8 T cell Responses by Targeting mTOR Signaling

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  DOI: 10.1016/j.isci.2022.103932
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8886054/
Jan 2022
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Weight loss and cystic disease progression in autosomal dominant polycystic kidney disease

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  DOI: 10.1016/j.isci.2021.103697
  
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sciencedirect.com/science/article/pii/S2589004221016679
Dec 2021
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BPS Publications

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1. scibot 21 Dec 2021
  
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  DOI: 10.1111/bph.15702
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15702
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Circ_0000518 promotes macrophage/microglia M1 polarization via the FUS/CaMKKβ/AMPK pathway to aggravate multiple sclerosis

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1. scibot 15 Dec 2021
  
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  DOI: 10.1016/j.neuroscience.2021.12.012
  
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sciencedirect.com/science/article/pii/S0306452221006369
Oct 2021
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Serum- and glucocorticoid-induced kinase drives hepatic insulin resistance by directly inhibiting AMP-activated protein kinase

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1. scibot 06 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109785
  
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sciencedirect.com/science/article/pii/S2211124721012444
Sep 2021
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Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species

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Crosstalk of hypothalamic chemerin, histamine, and AMPK in diet-and olanzapine-induced obesity in rats

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Decreased rates of cerebral protein synthesis measured in vivo in a mouse model of Tuberous Sclerosis Complex: unexpected consequences of reduced tuberin

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Isovitexin-Mediated Regulation of Microglial Polarization in Lipopolysaccharide-Induced Neuroinflammation via Activation of the CaMKKβ/AMPK-PGC-1α Signaling Axis

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AMPK-Mediated BECN1 Phosphorylation Promotes Ferroptosis by Directly Blocking System Xc– Activity

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LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms

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Sarcomere function activates a p53-dependent DNA damage response that promotes polyploidization and limits in vivo cell engraftment

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Cancer cells escape autophagy inhibition via NRF2-induced macropinocytosis

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Pulmonary inflammation-induced alterations in key regulators of mitophagy and mitochondrial biogenesis in murine skeletal muscle

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ApoE4 Impairs Neuron-Astrocyte Coupling of Fatty Acid Metabolism

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HCAR1/MCT1 Regulates Tumor Ferroptosis through the Lactate-Mediated AMPK-SCD1 Activity and Its Therapeutic Implications

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HNF4A and GATA6 Loss Reveals Therapeutically Actionable Subtypes in Pancreatic Cancer

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YAP1 regulates chondrogenic differentiation of ATDC5 promoted by temporary TNF-α stimulation through AMPK signaling pathway

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Pimozide Alleviates Hyperglycemia in Diet-Induced Obesity by Inhibiting Skeletal Muscle Ketone Oxidation

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Lactate Buildup at the Site of Chronic Inflammation Promotes Disease by Inducing CD4+ T Cell Metabolic Rewiring

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Inhibition of oncogenic Src induces FABP4-mediated lipolysis via PPARγ activation exerting cancer growth suppression

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p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

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Lymphocyte Activation Gene-3 Maintains Mitochondrial and Metabolic Quiescence in Naive CD4+ T Cells

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Serine Synthesis via PHGDH Is Essential for Heme Production in Endothelial Cells

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Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation

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TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease

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Pimozide reduces toxic forms of tau in TauC3 mice via AMPK‐mediated autophagy

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Endogenous Calcitonin Gene-Related Peptide Regulates Lipid Metabolism and Energy Homeostasis in Male Mice

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