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  1. Last 7 days
  2. aacrjournals.org aacrjournals.org
    First-in-Human Dose-Escalation Study of the First-in-Class PDE3A–SLFN12 Complex Inducer BAY 2666605 in Patients with Advanced Solid Tumors Coexpressing SLFN12 and PDE3A
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    1. scibot 17 Dec 2024
      RRID:AB_10634214

      DOI: 10.1158/1078-0432.CCR-24-2713

      Resource: (Bethyl Cat# A302-740A, RRID:AB_10634214)

      Curator: @scibot

      SciCrunch record: RRID:AB_10634214

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      RRID:AB_10634214
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    aacrjournals.org/clincancerres/article/30/24/5568/750433/First-in-Human-Dose-Escalation-Study-of-the-First
  3. Aug 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A PDE3A-SLFN12 Molecular Glue Exhibits Significant Antitumor Activity in TKI-Resistant Gastrointestinal Stromal Tumors
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    1. scibot 22 Aug 2024
      RRID:AB_10634214

      DOI: 10.1158/1078-0432.CCR-24-0096

      Resource: (Bethyl Cat# A302-740A, RRID:AB_10634214)

      Curator: @scibot

      SciCrunch record: RRID:AB_10634214

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      RRID:AB_10634214
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    ncbi.nlm.nih.gov/pmc/articles/PMC11325149/
  5. Feb 2022
  6. www.sciencedirect.com www.sciencedirect.com
    Multiple PDE3A modulators act as molecular glues promoting PDE3A-SLFN12 interaction and induce SLFN12 dephosphorylation and cell death
    1
    1. scibot 02 Feb 2022
      RRID:AB_10634214

      DOI: 10.1016/j.chembiol.2022.01.006

      Resource: (Bethyl Cat# A302-740A, RRID:AB_10634214)

      Curator: @scibot

      SciCrunch record: RRID:AB_10634214

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      RRID:AB_10634214
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    sciencedirect.com/science/article/pii/S245194562200006X
  7. Jan 2020
  8. www.sciencedirect.com www.sciencedirect.com
    Estrogen-Related Hormones Induce Apoptosis by Stabilizing Schlafen-12 Protein Turnover
    1
    1. scibot 13 Jan 2020
      RRID:AB_10634214

      DOI: 10.1016/j.molcel.2019.06.040

      Resource: (Bethyl Cat# A302-740A, RRID:AB_10634214)

      Curator: @ethanbadger

      SciCrunch record: RRID:AB_10634214

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      RRID:AB_10634214 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1097276519304976