82 Matching Annotations
  1. Sep 2025
  2. www.sciencedirect.com www.sciencedirect.com
    Rod-shaped microglia interact with neuronal dendrites to attenuate cortical excitability during TDP-43-related neurodegeneration
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    sciencedirect.com/science/article/pii/S1074761325003796
  3. Jun 2025
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Long-term muscarinic inhibition increases intrinsic excitability through the upregulation of A-type potassium currents in cortical neurons
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    pmc.ncbi.nlm.nih.gov/articles/PMC12149742/
  5. Aug 2024
  6. rupress.org rupress.org
    An evolutionarily conserved AnkyrinG-dependent motif clusters axonal K2P K+ channels
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    rupress.org/jcb/article/223/10/e202401140/276880/An-evolutionarily-conserved-AnkyrinG-dependent
  7. May 2024
  8. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Postsynaptic β1 spectrin maintains Na+ channels at the neuromuscular junction
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285894
  9. Dec 2023
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    Aberrant axon initial segment plasticity and intrinsic excitability of ALS hiPSC motor neurons
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    sciencedirect.com/science/article/pii/S2211124723015218
  11. Oct 2023
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    Antibody-directed extracellular proximity biotinylation reveals that Contactin-1 regulates axo-axonic innervation of axon initial segments
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    nature.com/articles/s41467-023-42273-8
  13. Jul 2023
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    Early developmental deletion of forebrain Ank2 causes seizure-related phenotypes by reshaping the synaptic proteome
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    sciencedirect.com/science/article/pii/S2211124723007957
  15. May 2023
  16. 52.53.155.43 52.53.155.43
    Spatially Resolved Proteomic Profiling Uncovers Structural and Functional Regulators of the Axon Initial Segment
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    52.53.155.43/1b0cedf04512903e90b9ef1858ffefd94df1235f/2023.03.06.531334v1.full-html.html
  17. Apr 2023
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Contextual fear response is modulated by M-type K+ channels and is associated with subtle structural changes of the axon initial segment in hippocampal GABAergic neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC10106335/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antibody-directed extracellular proximity biotinylation reveals Contactin-1 regulates axo-axonic innervation of axon initial segments
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    ncbi.nlm.nih.gov/pmc/articles/PMC10028829/
  20. Mar 2023
  21. 52.53.155.43 52.53.155.43
    NaV1.7 mRNA and protein expression in putative projection neurons of the human spinal dorsal horn
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    52.53.155.43/b5caca5e6aa2d35c58d7fbbd4b834fa3352e749d/2023.02.04.527110v1.full-html.html
  22. Aug 2022
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sensitivity to extracellular potassium underlies type-intrinsic differences in retinal ganglion cell excitability
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    ncbi.nlm.nih.gov/pmc/articles/PMC9390602/
  24. Jul 2022
  25. www.jneurosci.org www.jneurosci.org
    Direct Observation of Compartment-Specific Localization and Dynamics of Voltage-Gated Sodium Channels
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    jneurosci.org/content/42/28/5482
  26. May 2022
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    Differences in spike generation instead of synaptic inputs determine the feature selectivity of two retinal cell types
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    sciencedirect.com/science/article/pii/S0896627322003579
  28. Nov 2021
  29. journals.plos.org journals.plos.org
    Axon initial segment geometry in relation to motoneuron excitability
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    journals.plos.org/plosone/article
  30. Oct 2021
  31. www.sciencedirect.com www.sciencedirect.com
    Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchrony
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    sciencedirect.com/science/article/pii/S221112472101322X
  32. www.eneuro.org www.eneuro.org
    The type 2 diabetes factor methylglyoxal mediates axon initial segment shortening and alters neuronal function at the cellular and network levels
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    eneuro.org/content/8/5/ENEURO.0201-21.2021
  33. Sep 2021
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    Utilizing mouse optic nerve crush to examine CNS remyelination
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    sciencedirect.com/science/article/pii/S2666166721005025
  35. Aug 2021
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    Paradoxical hyperexcitability from NaV1.2 sodium channel loss in neocortical pyramidal cells
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    sciencedirect.com/science/article/pii/S2211124721009104
  37. journals.sagepub.com journals.sagepub.com
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    journals.sagepub.com/doi/10.1177/1759091418766175
  38. elifesciences.org elifesciences.org
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    elifesciences.org/articles/18426
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    frontiersin.org/article/10.3389/fncel.2014.00272/full
  40. www.molbiolcell.org www.molbiolcell.org
    Remodeling neuronal ER–PM junctions is a conserved nonconducting function of Kv2 plasma membrane ion channels
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    molbiolcell.org/doi/abs/10.1091/mbc.E18-05-0337
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6233057/
  42. Jul 2021
  43. www.sciencedirect.com www.sciencedirect.com
    Feedback-Driven Mechanisms between Microtubules and the Endoplasmic Reticulum Instruct Neuronal Polarity
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    sciencedirect.com/science/article/pii/S0896627319300571
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    nature.com/articles/s41598-018-32708-4
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Similar GABAA receptor subunit composition in somatic and axon initial segment synapses of hippocampal pyramidal cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC4990423/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of AKT Signaling Alters βIV Spectrin Distribution at the AIS and Increases Neuronal Excitability
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    ncbi.nlm.nih.gov/pmc/articles/PMC8278006/
  47. www.sciencedirect.com www.sciencedirect.com
    WDR47 protects neuronal microtubule minus ends from katanin-mediated severing
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    sciencedirect.com/science/article/pii/S2211124721007695
  48. May 2021
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRPM4 Expression During Postnatal Developmental of Mouse CA1 Pyramidal Neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC8113704/
  50. www.eneuro.org www.eneuro.org
    Essential Role of Somatic Kv2 Channels in High-Frequency Firing in Cartwheel Cells of the Dorsal Cochlear Nucleus
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    eneuro.org/content/8/3/ENEURO.0515-20.2021
  51. Apr 2021
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Structural Refinement of the Auditory Brainstem Neurons in Baboons During Perinatal Development
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    ncbi.nlm.nih.gov/pmc/articles/PMC8062779/
  53. www.sciencedirect.com www.sciencedirect.com
    Fragment-linking peptide design yields a high-affinity ligand for microtubule-based transport
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    sciencedirect.com/science/article/pii/S2451945621001495
  54. Feb 2021
  55. www.cell.com www.cell.com
    Genetic Single Neuron Anatomy Reveals Fine Granularity of Cortical Axo-Axonic Cells
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    cell.com/cell-reports/fulltext/S2211-1247(19)30211-6
  56. Dec 2020
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The palmitoyl acyltransferase ZDHHC14 controls Kv1-family potassium channel clustering at the axon initial segment
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    ncbi.nlm.nih.gov/pmc/articles/PMC7685708/
  58. Sep 2020
  59. elifesciences.org elifesciences.org
    The C-terminal helix 9 motif in rat cannabinoid receptor type 1 regulates axonal trafficking and surface expression
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    elifesciences.org/articles/44252
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ca2+ entry through NaV channels generates submillisecond axonal Ca2+ signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC7380941/
  61. www.sciencedirect.com www.sciencedirect.com
    Input-Output Relationship of CA1 Pyramidal Neurons Reveals Intact Homeostatic Mechanisms in a Mouse Model of Fragile X Syndrome
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    sciencedirect.com/science/article/pii/S2211124720309736
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    Accumulation of Neurofascin at nodes of Ranvier is regulated by a Paranodal Switch
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    jneurosci.org/content/40/30/5709
  63. elifesciences.org elifesciences.org
    Nodal β spectrins are required to maintain Na+ channel clustering and axon integrity
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    elifesciences.org/articles/52378
  64. www.sciencedirect.com www.sciencedirect.com
    TGF-β-Induced Phosphorylation of Usp9X Stabilizes Ankyrin-G and Regulates Dendritic Spine Development and Maintenance
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    sciencedirect.com/science/article/pii/S2211124720306380
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β spectrin-dependent and domain specific mechanisms for Na+ channel clustering
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    ncbi.nlm.nih.gov/pmc/articles/PMC7237202/
  66. www.molbiolcell.org www.molbiolcell.org
    Remodeling neuronal ER–PM junctions is a conserved nonconducting function of Kv2 plasma membrane ion channels | Molecular Biology of the Cell
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    molbiolcell.org/doi/10.1091/mbc.E18-05-0337
  67. Jan 2020
  68. www.sciencedirect.com www.sciencedirect.com
    Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis
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    sciencedirect.com/science/article/pii/S0896627319306920
  69. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
    Imaging of the Axon Initial Segment
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    currentprotocols.onlinelibrary.wiley.com/doi/full/10.1002/cpns.78
  70. www.sciencedirect.com www.sciencedirect.com
    Usp9X Controls Ankyrin-Repeat Domain Protein Homeostasis during Dendritic Spine Development
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    sciencedirect.com/science/article/pii/S0896627319309663
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    Reversal of peripheral nerve injury-induced neuropathic pain and cognitive dysfunction via genetic and tomivosertib targeting of MNK
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    nature.com/articles/s41386-019-0537-y
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of Auditory Experience on the Structural Plasticity of the AIS in the Mouse Brainstem Throughout the Lifespan
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    ncbi.nlm.nih.gov/pmc/articles/PMC6813928/
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    In Vivo Single-Cell Genotyping of Mouse Cortical Neurons Transfected with CRISPR/Cas9
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    sciencedirect.com/science/article/pii/S2211124719308046
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    Feedback-Driven Assembly of the Axon Initial Segment
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    sciencedirect.com/science/article/pii/S0896627319306555
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Feedback-Driven Mechanisms between Microtubules and the Endoplasmic Reticulum Instruct Neuronal Polarity
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  79. www.jneurosci.org www.jneurosci.org
    Glial βII spectrin contributes to paranode formation and maintenance
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    jneurosci.org/content/38/27/6063
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    An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons
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    Axo-axonic Innervation of Neocortical Pyramidal Neurons by GABAergic Chandelier Cells Requires AnkyrinG-Associated L1CAM
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    sciencedirect.com/science/article/pii/S0896627319301187
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    Maturation Dynamics of the Axon Initial Segment (AIS) of Newborn Dentate Granule Cells in Young Adult C57BL/6J Mice
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    jneurosci.org/content/39/9/1605
  85. Nov 2018
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    journals.sagepub.com/doi/full/10.1177/1759091418766175
  88. europepmc.org europepmc.org
    Type 2 Diabetes Leads to Axon Initial Segment Shortening in db/db Mice
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    europepmc.org/articles/PMC6002488/
  89. www.frontiersin.org www.frontiersin.org
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    frontiersin.org/article/10.3389/fncel.2018.00146/full
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    Methylglyoxal Disrupts Paranodal Axoglial Junctions via Calpain Activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC5944142/
  91. elifesciences.org elifesciences.org
    Embryonic and postnatal neurogenesis produce functionally distinct subclasses of dopaminergic neuron
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    elifesciences.org/articles/32373
  92. www.fasebj.org www.fasebj.org
    KCa2 channel localization and regulation in the axon initial segment | The FASEB Journal
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    fasebj.org/doi/full/10.1096/fj.201700605R
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    mTOR-dependent alterations of Kv1.1 subunit expression in the neuronal subset-specific Pten knockout mouse model of cortical dysplasia with epilepsy
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    ncbi.nlm.nih.gov/pmc/articles/PMC5824782/
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    Localized Myosin II Activity Regulates Assembly and Plasticity of the Axon Initial Segment
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    sciencedirect.com/science/article/pii/S089662731731187X
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Subcellular Localization and Activity of TRPM4 in Medial Prefrontal Cortex Layer 2/3
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    ncbi.nlm.nih.gov/pmc/articles/PMC5797675/
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Enhanced Transmission at the Calyx of Held Synapse in a Mouse Model for Angelman Syndrome
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    ncbi.nlm.nih.gov/pmc/articles/PMC5758499/
  97. Nov 2017
  98. link.springer.com link.springer.com
    Immunohistochemical Procedures for Characterizing the Retinal Expression Patterns of Cre Driver Mouse Lines
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    link.springer.com/protocol/10.1007/978-1-4939-7169-5_12
  99. www.pnas.org www.pnas.org
    LGI1 tunes intrinsic excitability by regulating the density of axonal Kv1 channels
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    pnas.org/content/early/2017/06/28/1618656114.long
  100. www.sciencedirect.com www.sciencedirect.com
    Bassoon Controls Presynaptic Autophagy through Atg5
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Similar GABAA receptor subunit composition in somatic and axon initial segment synapses of hippocampal pyramidal cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC4990423/
  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The paranodal cytoskeleton clusters Na+ channels at nodes of Ranvier
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    ncbi.nlm.nih.gov/pmc/articles/PMC5279941/
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    Multiscale Analysis of Neurite Orientation and Spatial Organization in Neuronal Images
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    link.springer.com/article/10.1007/s12021-016-9306-9
  104. www.sciencedirect.com www.sciencedirect.com
    Developing high-quality mouse monoclonal antibodies for neuroscience research – approaches, perspectives and opportunities
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    sciencedirect.com/science/article/pii/S1871678415002587
  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    JNK1 controls dendritic field size in L2/3 and L5 of the motor cortex, constrains soma size, and influences fine motor coordination
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    ncbi.nlm.nih.gov/pmc/articles/PMC4162472/
  106. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sodium channel β1 subunit localizes to axon initial segments of excitatory and inhibitory neurons and shows regional heterogeneity in mouse brain
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    onlinelibrary.wiley.com/doi/10.1002/cne.23715/full