139 Matching Annotations
  1. May 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal proteomic profiling of cellular responses to NLRP3 agonists
    1
    1. scibot 01 May 2024
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      DOI: 10.1101/2024.04.19.590338

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    ncbi.nlm.nih.gov/pmc/articles/PMC11042255/
  3. Apr 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Epithelial UNC-23 limits mechanical stress to maintain glia-neuron architecture in C. elegans
    1
    1. scibot 26 Apr 2024
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      DOI: 10.1016/j.devcel.2024.04.005

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    sciencedirect.com/science/article/pii/S1534580724002302
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Suppression of Cofilin function in the somatosensory cortex alters social contact behavior in the BTBR mouse inbred line
    1
    1. scibot 13 Apr 2024
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      DOI: 10.1093/cercor/bhae136

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    ncbi.nlm.nih.gov/pmc/articles/PMC11008688/
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    Heterogeneity of tethered agonist signaling in adhesion G protein-coupled receptors
    1
    1. scibot 12 Apr 2024
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      DOI: 10.1016/j.chembiol.2024.03.004

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    sciencedirect.com/science/article/pii/S245194562400120X
  7. Mar 2024
  8. www.biorxiv.org www.biorxiv.org
    PDE4 inhibitor Rolipram represses hedgehog signaling via ubiquitin-mediated proteolysis of GLI transcription factors to regress breast cancer
    1
    1. scibot 21 Mar 2024
      RRID:AB_10691311

      DOI: 10.1101/2024.03.03.583221

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    biorxiv.org/content/10.1101/2024.03.03.583221v1
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    Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1
    2
    1. scibot 19 Mar 2024
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      DOI: 10.1016/j.molcel.2024.02.035

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    2. scibot 19 Mar 2024
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      DOI: 10.1016/j.molcel.2024.02.035

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    sciencedirect.com/science/article/pii/S109727652400176X
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pip5k1γ regulates axon formation by limiting Rap1 activity
    1
    1. scibot 07 Mar 2024
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      DOI: 10.26508/lsa.202302383

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    ncbi.nlm.nih.gov/pmc/articles/PMC10912816/
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    Glycerophosphodiesters inhibit lysosomal phospholipid catabolism in Batten disease
    1
    1. scibot 06 Mar 2024
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    sciencedirect.com/science/article/pii/S1097276524001254
  12. Feb 2024
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    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
    1
    1. scibot 23 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001736
  14. 52.53.155.43 52.53.155.43
    Regulation of the intestinal Na+/H+ exchanger NHE3 by AMP-activated kinase is dependent on phosphorylation of NHE3 at S555 and S563
    2
    1. scibot 22 Feb 2024
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    52.53.155.43/f69a85cf28386bd1400aa251e3a5d55dee473eb1/han-et-al-2024-regulation-of-the-intestinal-na-h-exchanger-nhe3-by-amp-activated-kinase-is-dependent-on-phosphorylation-html.html
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    C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line
    2
    1. scibot 15 Feb 2024
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      DOI: 10.1016/j.molcel.2024.01.014

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    2. scibot 15 Feb 2024
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      DOI: 10.1016/j.molcel.2024.01.014

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  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperation between PRMT1 and PRMT6 drives lung cancer health disparities among Black/African American men
    1
    1. scibot 03 Feb 2024
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      DOI: 10.1016/j.isci.2024.108858

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    ncbi.nlm.nih.gov/pmc/articles/PMC10830871/
  17. Dec 2023
  18. www.sciencedirect.com www.sciencedirect.com
    Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics
    1
    1. scibot 17 Dec 2023
      RRID:AB_10691311

      DOI: 10.1016/j.chembiol.2023.11.010

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    sciencedirect.com/science/article/pii/S2451945623004257
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitoguardin 1 and 2 promote granulosa cell proliferation by activating AKT and regulating the Hippo-YAP1 signaling pathway
    1
    1. scibot 01 Dec 2023
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      DOI: 10.1038/s41419-023-06312-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10682431/
  20. Oct 2023
  21. www.embopress.org www.embopress.org
    The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes
    1
    1. scibot 20 Oct 2023
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      DOI: 10.15252/embr.202356815

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    embopress.org/doi/10.15252/embr.202356815
  22. 52.53.155.43 52.53.155.43
    PIIS0092867423009650-html.html
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.cell.2023.08.032

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  23. Sep 2023
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    Impact of SARS-CoV-2 ORF6 and its variant polymorphisms on host responses and viral pathogenesis
    1
    1. scibot 30 Sep 2023
      RRID:AB_10691311

      DOI: 10.1016/j.chom.2023.08.003

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    sciencedirect.com/science/article/pii/S1931312823003281
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    Lysosomal cyst(e)ine storage potentiates tolerance to oxidative stress in cancer cells
    1
    1. scibot 30 Sep 2023
      RRID:AB_10691311

      DOI: 10.1016/j.molcel.2023.08.032

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    sciencedirect.com/science/article/pii/S1097276523006950
  26. www.biorxiv.org www.biorxiv.org
    Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
    1
    1. scibot 30 Sep 2023
      RRID:AB_10691311

      DOI: 10.1101/2023.09.25.559255

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    biorxiv.org/content/10.1101/2023.09.25.559255v1
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    Ectopic expression of DOCK8 regulates lysosome-mediated pancreatic tumor cell invasion
    1
    1. scibot 01 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113042

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    sciencedirect.com/science/article/pii/S2211124723010537
  28. Aug 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    5-HT1A and 5-HT2B receptor interaction and co-clustering regulate serotonergic neuron excitability. 5-HT receptor cross-talks shape 5-HT neuron activity
    1
    1. scibot 16 Aug 2023
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      DOI: 10.1016/j.isci.2023.107401

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    ncbi.nlm.nih.gov/pmc/articles/PMC10415917/
  30. Jul 2023
  31. www.sciencedirect.com www.sciencedirect.com
    Structural basis for membrane-proximal proteolysis of substrates by ADAM10
    1
    1. scibot 29 Jul 2023
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      DOI: 10.1016/j.cell.2023.06.026

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    sciencedirect.com/science/article/abs/pii/S009286742300733X
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    Disruption of neuronal RHEB signaling impairs oligodendrocyte differentiation and myelination through mTORC1-DLK1 axis
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112801

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    sciencedirect.com/science/article/pii/S2211124723008124
  33. Jun 2023
  34. www.sciencedirect.com www.sciencedirect.com
    A mitochondrial iron-responsive pathway regulated by DELE1
    1
    1. scibot 21 Jun 2023
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      DOI: 10.1016/j.molcel.2023.05.031

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    sciencedirect.com/science/article/pii/S1097276523004136
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    NLRP12-PANoptosome activates PANoptosis and pathology in response to heme and PAMPs
    1
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  36. May 2023
  37. www.sciencedirect.com www.sciencedirect.com
    Unconventional initiation of PINK1/Parkin mitophagy by Optineurin
    1
    1. scibot 19 May 2023
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      DOI: 10.1016/j.molcel.2023.04.021

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    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
    1
    1. scibot 05 May 2023
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      DOI: 10.1016/j.ebiom.2022.104155

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    sciencedirect.com/science/article/pii/S235239642200336X
  39. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
    1
    1. scibot 05 May 2023
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      DOI: 10.1002/cac2.12332

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    onlinelibrary.wiley.com/doi/10.1002/cac2.12332
  40. www.biorxiv.org www.biorxiv.org
    APOE traffics to astrocyte lipid droplets and modulates triglyceride saturation and droplet size
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      DOI: 10.1101/2023.04.28.538740

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    biorxiv.org/content/10.1101/2023.04.28.538740v1
  41. Apr 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Proteomic discovery of chemical probes that perturb protein complexes in human cells
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    Transcriptional kinetic synergy: A complex landscape revealed by integrating modeling and synthetic biology
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    sciencedirect.com/science/article/pii/S2405471223000558
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    DTX3L E3 ligase targets p53 for degradation at poly ADP-ribose polymerase-associated DNA damage sites
    1
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    sciencedirect.com/science/article/pii/S2589004223005217
  45. Mar 2023
  46. link.springer.com link.springer.com
    VE-822 upregulates the deubiquitinase OTUD1 to stabilize FHL1 to inhibit the progression of lung adenocarcinoma
    1
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      DOI: 10.1007/s13402-023-00793-x

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    The tetraspan LHFPL5 is critical to establish maximal force sensitivity of the mechanotransduction channel of cochlear hair cells
    1
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      DOI: 10.1016/j.celrep.2023.112245

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    sciencedirect.com/science/article/pii/S2211124723002565
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    Redox proteomics combined with proximity labeling enables monitoring of localized cysteine oxidation in cells
    1
    1. scibot 11 Mar 2023
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    sciencedirect.com/science/article/pii/S2451945623000557
  49. Feb 2023
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proximity labeling reveals a new in vivo network of interactors for the histone demethylase KDM5
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      DOI: 10.1186/s13072-023-00481-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC9938590/
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    Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation
    1
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      DOI: 10.1016/j.celrep.2023.112033

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    Site-Specific Incorporation of Genetically Encoded Photo-Crosslinkers Locates the Heteromeric Interface of a GPCR Complex in Living Cells
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    The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction
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    Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ε
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    An epilepsy‐associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model
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    The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development
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    Phase Separation of Disease-Associated SHP2 Mutants Underlies MAPK Hyperactivation
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    Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling
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    Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription
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    Compounds targeting YadC of uropathogenic Escherichia coli and its host receptor annexin A2 decrease bacterial colonization in bladder
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    Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer
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    Lack of PDZD7 long isoform disrupts ankle‐link complex and causes hearing loss in mice
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    Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer
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    Rewiring Neuronal Glycerolipid Metabolism Determines the Extent of Axon Regeneration
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      DOI: 10.1016/j.celrep.2019.03.087

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      DOI: 10.1016/j.molcel.2019.02.029

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    LRH1-driven transcription factor circuitry for hepatocyte identity: Super-enhancer cistromic analysis
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    1. scibot 12 Jan 2020
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      DOI: 10.1016/j.ebiom.2018.12.056

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  157. Nov 2018
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    GRXCR2 Regulates Taperin Localization Critical for Stereocilia Morphology and Hearing
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    Protein Barcodes Enable High-Dimensional Single-Cell CRISPR Screens
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    Phosphorylation-Mediated IFN-γR2 Membrane Translocation Is Required to Activate Macrophage Innate Response
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    BRCA1 Mutation-Specific Responses to 53BP1 Loss-Induced Homologous Recombination and PARP Inhibitor Resistance
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    sciencedirect.com/science/article/pii/S0960982218308601
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    Mechanotransduction by PCDH15 Relies on a Novel cis-Dimeric Architecture
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    Dual Requirement of CHD8 for Chromatin Landscape Establishment and Histone Methyltransferase Recruitment to Promote CNS Myelination and Repair
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    SHRED Is a Regulatory Cascade that Reprograms Ubr1 Substrate Specificity for Enhanced Protein Quality Control during Stress
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    An efficient and scalable pipeline for epitope tagging in mammalian stem cells using Cas9 ribonucleoprotein
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  167. www.sciencedirect.com www.sciencedirect.com
    Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element
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    Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors
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    Abnormal Cell Sorting Underlies the Unique X-Linked Inheritance of PCDH19 Epilepsy
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    As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid
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    sciencedirect.com/science/article/pii/S1550413117307167
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    NRF1 Is an ER Membrane Sensor that Is Central to Cholesterol Homeostasis
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  172. Nov 2017
  173. www.sciencedirect.com www.sciencedirect.com
    ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer
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      Curator: @chewbeccax

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    Matching NLR Immune Receptors to Autoimmunity in camta3 Mutants Using Antimorphic NLR Alleles
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    Phosphoribosylation of Ubiquitin Promotes Serine Ubiquitination and Impairs Conventional Ubiquitination
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    1. scibot 08 Nov 2017
      AB_10691311

      Curator: @chewbeccax

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    sciencedirect.com/science/article/pii/S0092867416315914
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    A Two-Immunoglobulin-Domain Transmembrane Protein Mediates an Epidermal-Neuronal Interaction to Maintain Synapse Density
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    1. scibot 08 Nov 2017
      AB_10691311

      Curator: @jcabotaj

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