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Target cell adhesion limits macrophage phagocytosis and promotes trogocytosis

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Jan 2026
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Extracellular matrix stiffness drives post-mitotic nuclear pore complex assembly to promote neuroblastoma pathogenesis

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Nov 2025
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MIAT-DHX9 spatiotemporal expression drives venous neointimal hyperplasia through nucleolar homeostasis and mitotic progression

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Sep 2025
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A novel MAP7D1 mutation causes mitotic defects and RPS14 accumulation in Shwachman−Diamond syndrome patient cells

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LncRNA EUDAL shapes tumor cell response to hypoxia-induced constitutive EGFR activation and promotes chemoresistance in oral cancer

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Aug 2025
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IRE1α-XBP1s axis is required for BCG-induced trained immunity against viral infection by inhibiting AHR signaling

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Distinct specificity and functions of PRC2 subcomplexes in human stem cells and cardiac differentiation

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Scavenger Receptor CD36 in Tumor-Associated Macrophages Promotes Cancer Progression by Dampening Type I Interferon Signaling

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Jul 2025
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Effective Treatment of Disseminated Prostate Cancer Using CD46-Targeted 225Ac Therapy

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May 2025
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PIM kinase control of CD8 T cell protein synthesis and cell trafficking

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IMPDH inhibition induces DNA replication stress and ATR sensitivity in Merkel cell carcinoma

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Feb 2025
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Hepatic sphingomyelin phosphodiesterase 3 promotes steatohepatitis by disrupting membrane sphingolipid metabolism

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N-cadherin-triggered myosin II inactivation provides tumor cells with a mechanical cell competition advantage and chemotherapy resistance

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1. scibot 25 Feb 2025
  
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Nov 2024
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IL-21/IL-21R signaling renders acute myeloid leukemia stem cells more susceptible to cytarabine treatment and CAR T cell therapy

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Sep 2024
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GABAergic neuronal lineage development determines clinically actionable targets in diffuse hemispheric glioma, H3G34-mutant

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Aug 2024
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Protocol for quantifying drug sensitivity in 3D patient-derived ovarian cancer models

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Jun 2024
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Anti-tumor effects of tirbanibulin in squamous cell carcinoma cells are mediated via disruption of tubulin-polymerization

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1. scibot 13 Jun 2024
  
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May 2024
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RGD Targeted Magnetic Ferrite Nanoparticles Enhance Antitumor Immunotherapeutic Efficacy by Activating STING Signaling Pathway

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Apr 2024
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1-s2.0-S2589004224002839-main-html.html

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Oct4 controls basement membrane development during human embryogenesis

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Mar 2024
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An engineering strategy to target activated EGFR with CAR T cells

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1-s2.0-S2589004224002839-main-html.html

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Jan 2024
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Atrial natriuretic peptide signaling co-regulates lipid metabolism and ventricular conduction system gene expression in the embryonic heart

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Dec 2023
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Hexamethylene amiloride synergizes with venetoclax to induce lysosome-dependent cell death in acute myeloid leukemia

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Oct 2023
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CD4+ T cell-derived IL21 regulates stem cell fate in acute myeloid leukemia by activation of p38-MAPK signaling

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GABA Regulates Electrical Activity and Tumor Initiation in Melanoma

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  DOI: 10.1158/2159-8290.CD-23-0389
  
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Aug 2023
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cd-23-0389-html.html

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May 2023
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Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway

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Apr 2023
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Optimal HSF1 activation in response to acute cold stress in BAT requires nuclear TXNIP

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  DOI: 10.1016/j.isci.2023.106538
  
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Mar 2023
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Disrupted myelin lipid metabolism differentiates frontotemporal dementia caused by GRN and C9orf72 gene mutations

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  DOI: 10.1186/s40478-023-01544-7
  
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Jan 2023
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SMN promotes mitochondrial metabolic maturation during myogenesis by regulating the MYOD-miRNA axis

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1. scibot 15 Jan 2023
  
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  DOI: 10.26508/lsa.202201457
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9834662/
Nov 2022
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Androgens improve ovarian follicle function impaired by glucocorticoids through an androgen-IGF1-FSH synergistic effect

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1. scibot 04 Nov 2022
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9627217/
Oct 2022
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COMPREHENSIVE DRUG RESPONSE PROFILING AND PAN-OMIC ANALYSIS IDENTIFIED THERAPEUTIC CANDIDATES AND PROGNOSTIC BIOMARKERS FOR ASIAN CHOLANGIOCARCINOMA

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1. scibot 26 Oct 2022
  
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  DOI: 10.1016/j.isci.2022.105182
  
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MCM7 supports the stemness of bladder cancer stem-like cells by enhancing autophagic flux

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Ets21C sustains a pro-regenerative transcriptional program in blastema cells of Drosophila imaginal discs

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BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen

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Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma

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MLL::AF9 degradation induces rapid changes in transcriptional elongation and subsequent loss of an active chromatin landscape

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A chemical probe targeting the PWWP domain alters NSD2 nucleolar localization

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Force-dependent activation of actin elongation factor mDia1 protects the cytoskeleton from mechanical damage and promotes stress fiber repair

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AKIRIN2 controls the nuclear import of proteasomes in vertebrates

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Functional heterogeneity of POMC neurons relies on mTORC1 signaling

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Intestinal microbiota modulates adrenomedullary response through Nod1 sensing in chromaffin cells

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USP8 deubiquitinates the leptin receptor and is necessary for leptin-mediated synapse formation

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Hypothalamic bile acid-TGR5 signaling protects from obesity

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UTX promotes CD8+ T cell-mediated antiviral defenses but reduces T cell durability

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Constitutive androstane receptor induced-hepatomegaly is partially via yes-associated protein activation

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Leptin controls glutamatergic synaptogenesis and NMDA-receptor trafficking via Fyn kinase regulation of NR2B

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Interferon-λ Enhances the Differentiation of Naive B Cells into Plasmablasts via the mTORC1 Pathway

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Quantitative analysis of how Myc controls T cell proteomes and metabolic pathways during T cell activation

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Survival of Single Positive Thymocytes Depends upon Developmental Control of RIPK1 Kinase Signaling by the IKK Complex Independent of NF-κB

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The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling

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Flotillin-Dependent Membrane Microdomains Are Required for Functional Phagolysosomes against Fungal Infections

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Hydrogen sulfide suppresses homocysteine-induced glial activation and inflammatory response

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Glutathione transferase P silencing promotes neuronal differentiation of retinal R28 cells

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Identification of an Early Unipotent Neutrophil Progenitor with Pro-tumoral Activity in Mouse and Human Bone Marrow

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RHOA G17V Induces T Follicular Helper Cell Specification and Promotes Lymphomagenesis

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A Metabolic Basis for Endothelial-to-Mesenchymal Transition

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Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy

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