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Self-amplifying RNA enables rapid, durable, integration-free programming of hiPSCs

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  DOI: 10.1016/j.crmeth.2026.101602
  
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sciencedirect.com/science/article/pii/S2667237526003036
Jul 2026
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Multi-omics integration combined with multi-source weighted analysis identifies a key microRNA combination that reverses α-synuclein aggregation and pathological phenotypes in Parkinson's disease

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1. scibot 12 Jul 2026
  
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  DOI: 10.1016/j.ijbiomac.2026.153252
  
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sciencedirect.com/science/article/pii/S0141813026031922
Jun 2026
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Patient-specific midbrain organoids with CRISPR correction recapitulate neuronopathic Gaucher disease phenotypes and enable evaluation of novel therapies

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1. scibot 26 Jun 2026
  
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  DOI: 10.7554/eLife.109518
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13290227/
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Three-dimensional direct neuronal reprogramming for modeling Alzheimer’s disease neuropathology

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1. scibot 18 Jun 2026
  
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  DOI: 10.1038/s41596-026-01388-0
  
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nature.com/articles/s41596-026-01388-0
May 2026
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tRNA-derived fragments elevated in Alzheimer’s disease facilitate Tau aggregation

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1. scibot 29 May 2026
  
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  DOI: 10.64898/2026.05.17.725757
  
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biorxiv.org/content/10.64898/2026.05.17.725757v1
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AMPK-p38 axis converts human pluripotent stem cells to naive state

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1. scibot 01 May 2026
  
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  DOI: 10.1016/j.isci.2026.115569
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13122662/
Jan 2026
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Cell-type resolved protein atlas of brain lysosomes identifies SLC45A1-associated disease as a lysosomal disorder

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1. scibot 23 Jan 2026
  
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  DOI: 10.1016/j.cell.2025.12.012
  
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sciencedirect.com/science/article/pii/S0092867425014254
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Mapping spatial organization of in vitro neuronal networks using high-content imaging

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  DOI: 10.1038/s41598-025-29250-5
  
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nature.com/articles/s41598-025-29250-5
Sep 2025
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Multi-omics integration reveals key miRNAs, immune inflammation, and signaling pathways in Alzheimer's disease: Implications for targeted therapy

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  DOI: 10.1016/j.ijbiomac.2025.147874
  
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sciencedirect.com/science/article/pii/S0141813025084314
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A combined enteric neuron-gastric tumor organoid reveals metabolic vulnerabilities in gastric cancer

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  DOI: 10.1016/j.stem.2025.08.006
  
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sciencedirect.com/science/article/pii/S193459092500298X
May 2025
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RNF13 variants L311S and L312P associated with developmental epileptic encephalopathy alter dendritic organization in hippocampal neurons

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1. scibot 17 May 2025
  
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  DOI: 10.1016/j.ibneur.2025.04.004
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12018061/
Mar 2025
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Compact transcription factor cassettes generate functional, engraftable motor neurons by direct conversion

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1. scibot 14 Mar 2025
  
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  DOI: 10.1016/j.cels.2025.101206
  
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sciencedirect.com/science/article/pii/S2405471225000390
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Proliferation history and transcription factor levels drive direct conversion to motor neurons

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1. scibot 14 Mar 2025
  
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  DOI: 10.1016/j.cels.2025.101205
  
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sciencedirect.com/science/article/pii/S2405471225000389
Jan 2025
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Fate erasure logic of gene networks underlying direct neuronal conversion of somatic cells by microRNAs

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1. scibot 07 Jan 2025
  
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  DOI: 10.1016/j.celrep.2024.115153
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11834941/
Nov 2024
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Potassium ion channel modulation at cancer-neural interface enhances neuronal excitability in epileptogenic glioblastoma multiforme

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1. scibot 14 Nov 2024
  
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  DOI: 10.1016/j.neuron.2024.10.016
  
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sciencedirect.com/science/article/pii/S0896627324007372
Sep 2024
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APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival

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1. scibot 25 Sep 2024
  
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  DOI: 10.1016/j.neuron.2020.08.011
  
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cell.com/neuron/abstract/S0896-6273(20)30642-5
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Cell-autonomous role of Presenilin in age-dependent survival of cortical interneurons

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1. scibot 25 Sep 2024
  
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  DOI: 10.1186/s13024-020-00419-y
  
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link.springer.com/article/10.1186/s13024-020-00419-y
May 2024
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Effective cryopreservation of human brain tissue and neural organoids

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  DOI: 10.1016/j.crmeth.2024.100777
  
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sciencedirect.com/science/article/pii/S2667237524001218
Feb 2024
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Modeling the precise interaction of glioblastoma with human brain region-specific organoids

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1. scibot 28 Feb 2024
  
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  DOI: 10.1016/j.isci.2024.109111
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10882168/
Jan 2024
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Genetic variants affecting NQO1 protein levels impact the efficacy of idebenone treatment in Leber hereditary optic neuropathy

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1. scibot 25 Jan 2024
  
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  DOI: 10.1016/j.xcrm.2023.101383
  
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sciencedirect.com/science/article/pii/S2666379123006122
Dec 2023
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The circadian regulator PER1 promotes cell reprogramming by inhibiting inflammatory signaling from macrophages

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  DOI: 10.1371/journal.pbio.3002419
  
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journals.plos.org/plosbiology/article
Oct 2023
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SARS-CoV-2 hampers dopamine production in iPSC-derived dopaminergic neurons

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1. scibot 06 Oct 2023
  
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  DOI: 10.1016/j.yexmp.2023.104874
  
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sciencedirect.com/science/article/pii/S0014480023000254
Aug 2023
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s41596-023-00861-4-html.html

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1. scibot 17 Aug 2023
  
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  DOI: 10.1038/s41593-018-0175-4
  
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52.53.155.43/8a097cc29245bd27fcbce4843d2d164fee9b0176/s41596-023-00861-4-html.html
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Optimized protocol for the generation of functional human induced-pluripotent-stem-cell-derived dopaminergic neurons

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1. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.xpro.2023.102486
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10400954/
Jul 2023
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Upregulation of EphA4 deteriorate brain damage by shifting microglia M1-polarization via NF-κB signaling after focal cerebral ischemia in rats

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1. scibot 21 Jul 2023
  
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  DOI: 10.1016/j.heliyon.2023.e18429
  
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sciencedirect.com/science/article/pii/S2405844023056372
Jun 2023
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SRSF10 regulates proliferation of neural progenitor cells and affects neurogenesis in developing mouse neocortex

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1. scibot 24 Jun 2023
  
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  DOI: 10.1016/j.isci.2023.107042
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10285642/
May 2023
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Neurotrophins and their receptors, novel therapeutic targets for pelvic pain in endometriosis, are coordinately regulated by interleukin-1β via the JNK signaling pathway

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1. scibot 10 May 2023
  
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  DOI: 10.1016/j.ajpath.2023.04.007
  
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sciencedirect.com/science/article/pii/S0002944023001645
Feb 2023
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α-Synuclein decoy peptide protects mice against α-synuclein-induced memory loss

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1. scibot 15 Feb 2023
  
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  DOI: 10.1111/cns.14120
  
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onlinelibrary.wiley.com/doi/10.1111/cns.14120
Nov 2022
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Citrate shuttling in astrocytes is required for processing cocaine-induced neuron-derived excess peroxidated fatty acids

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  DOI: 10.1016/j.isci.2022.105407
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9646946/
Oct 2022
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Integrin-KCNB1 potassium channel complexes regulate neocortical neuronal development and are implicated in epilepsy

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  DOI: 10.1038/s41418-022-01072-2
  
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nature.com/articles/s41418-022-01072-2
Sep 2022
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Metabolic Profile Variations along the Differentiation of Human-Induced Pluripotent Stem Cells to Dopaminergic Neurons

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1. scibot 24 Sep 2022
  
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  DOI: 10.3390/biomedicines10092069
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9495704/
Aug 2022
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DNGR-1-tracing marks an ependymal cell subset with damage-responsive neural stem cell potential

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1. scibot 23 Aug 2022
  
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  DOI: 10.1016/j.devcel.2022.07.012
  
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sciencedirect.com/science/article/pii/S1534580722005299
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β-Glucocerebrosidase Deficiency Activates an Aberrant Lysosome-Plasma Membrane Axis Responsible for the Onset of Neurodegeneration

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1. scibot 16 Aug 2022
  
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  DOI: 10.3390/cells11152343
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9367513/
Jul 2022
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Pathological mitophagy disrupts mitochondrial homeostasis in Leber’s hereditary optic neuropathy

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1. scibot 27 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111124
  
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Pharmacotherapy alleviates pathological changes in human direct reprogrammed neuronal cell model of myotonic dystrophy type 1

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Patient-Derived Tumor Organoids for Guidance of Personalized Drug Therapies in Recurrent Glioblastoma

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Recapitulation of endogenous 4R tau expression and formation of insoluble tau in directly reprogrammed human neurons

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Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy

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ErbB4 mediates amyloid β-induced neurotoxicity through JNK/tau pathway activation: implications for Alzheimer’s disease

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Modeling Patient-Derived Glioblastoma with Cerebral Organoids

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ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma

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BPS Publications

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Untitled document

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Sprouty1 regulates neuritogenesis and survival of cortical neurons

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Calsyntenin-1 Negatively Regulates ICAM5 Accumulation in Postsynaptic Membrane and Influences Dendritic Spine Maturation in a Mouse Model of Fragile X Syndrome

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Untitled document

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Inhibition of CD38 and supplementation of nicotinamide riboside ameliorate lipopolysaccharide-induced microglial and astrocytic neuroinflammation by increasing NAD+

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Axonal generation of amyloid-β from palmitoylated APP in mitochondria-associated endoplasmic reticulum membranes

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Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs

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Refinement of a differentiation protocol using neuroblastoma SH-SY5Y cells for use in neurotoxicology research

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Generation of human iPS cell line IBCHi002-A from spinocerebellar ataxia type 3/Machado-Joseph disease patient's fibroblasts

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Modular and Distinct Plexin-A4/FARP2/Rac1 Signaling Controls Dendrite Morphogenesis

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  monoclonal rabbit anti-MAP2
  
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Antisense oligonucleotide therapy rescues aggresome formation in a novel spinocerebellar ataxia type 3 human embryonic stem cell line

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SETD5 Regulates Chromatin Methylation State and Preserves Global Transcriptional Fidelity during Brain Development and Neuronal Wiring

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Brain Endothelial Cells Maintain Lactate Homeostasis and Control Adult Hippocampal Neurogenesis

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Generation of human iPS cell line IBCHi001-A from dentatorubral–pallidoluysian atrophy patient's fibroblasts

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Modeling Patient-Derived Glioblastoma with Cerebral Organoids

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CRISPR Activation Screens Systematically Identify Factors that Drive Neuronal Fate and Reprogramming

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Intrinsic Immunity Shapes Viral Resistance of Stem Cells

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Brain‐derived neurotrophic factor/neurotrophin 3 regulate axon initial segment location and affect neuronal excitability in cultured hippocampal neurons

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