72 Matching Annotations
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    Discovery and Preclinical Validation of a Clinically Optimized Mitochondrial Complex I Modulator for Alzheimer’s Disease
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    biorxiv.org/content/10.64898/2026.04.10.717554v1
  3. Mar 2026
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  5. Feb 2026
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    Epigenetic regulation by oleacein mitigates IL-1β-induced inflammation in human SW982 synovial cells
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    pubs.rsc.org/en/content/articlehtml/2026/fo/d5fo03172a
  7. Jan 2026
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    Myeloid CD209 impairs T-cell activation by inducing ICAM-2–ERM–dependent cortical stiffening
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    biorxiv.org/content/10.64898/2026.01.19.699861v1
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    Macrophage migration inhibitory factor of zoonotic Giardia duodenalis triggers TLR4-MAPK/AKT/NLRP3 pathways to regulate inflammatory response
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    Scaffolding-dependent CASP1 constrains excessive cell-intrinsic inflammatory signaling in leukemia
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  11. Dec 2025
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Defining the antitumor mechanism of action of a clinical-stage compound as a selective degrader of the nuclear pore complex
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  13. Nov 2025
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    Prolyl endopeptidase is a multifunctional host factor required for FMDV infection
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  15. Sep 2025
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    Ubiquitination-activated TAB–TAK1–IKK–NF-κB axis modulates gene expression for cell survival in the lysosomal damage response
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    Sigma-1 receptor counteracts non-cell-autonomous poly-PR-induced astrocytic oxidative stress in C9orf72 ALS
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    Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer's disease
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    sciencedirect.com/science/article/pii/S2352396425003688
  19. Jul 2025
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    Glucose restriction shapes pre-metastatic innate immune landscapes in the lung through exosomal TRAIL
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    The immune response against cancer is modulated by stromal cell fibronectin
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    sciencedirect.com/science/article/pii/S1476558625000764
  22. Jun 2025
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA shielding of P65 is required to potentiate oncogenic inflammation in TET2 mutated clonal hematopoiesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11611684/
  24. May 2025
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A bacterial network of T3SS effectors counteracts host pro-inflammatory responses and cell death to promote infection
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  26. Apr 2025
  27. 52.53.155.43 52.53.155.43
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    Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway
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  29. Mar 2025
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic assessment of a novel mitochondrial complex I inhibitor in in vitro and in vivo models of Alzheimer’s disease
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  31. Feb 2025
  32. 52.53.155.43 52.53.155.43
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  34. Dec 2024
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    MAPK14/p38α shapes the molecular landscape of endometrial cancer and promotes tumorigenic characteristics
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    Bivalent SMAC mimetic APG-1387 reduces HIV reservoirs and limits viral rebound in humanized mice
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  37. Nov 2024
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    IL-21/IL-21R signaling renders acute myeloid leukemia stem cells more susceptible to cytarabine treatment and CAR T cell therapy
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    Kaempferol attenuates hyperuricemia combined with gouty arthritis via urate transporters and NLRP3/NF-κB pathway modulation
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  40. Aug 2024
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    Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection
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  42. Jul 2024
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monoacylglycerol acyltransferase-2 inhibits colorectal carcinogenesis in APCmin+/− mice
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    Lack of canonical thyroid hormone receptor α signaling changes regulatory T cell phenotype in female mice
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    Targeting type I DED interactions at the DED filament serves as a sensitive switch for cell fate decisions
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  46. Jun 2024
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    Monomethyl fumarate attenuates lung Ischemia/Reperfusion injury by disrupting the GAPDH/Siah1 signaling cascade
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    Hippo-PKCζ-NFκB signaling axis: A druggable modulator of chondrocyte responses to mechanical stress
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  49. Apr 2024
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    CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo
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  51. Feb 2024
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    The IRAK1/IRF5 axis initiates IL-12 response by dendritic cells and control of Toxoplasma gondii infection
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  53. Nov 2023
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    STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells
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  55. Oct 2023
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    LRRK2 G2019S promotes astrocytic inflammation induced by oligomeric α-synuclein through NF-κB pathway
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    CD4+ T cell-derived IL21 regulates stem cell fate in acute myeloid leukemia by activation of p38-MAPK signaling
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  58. Sep 2023
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    CGK733 alleviates ovariectomy-induced bone loss through blocking RANKL-mediated Ca2+ oscillations and NF-κB/MAPK signaling pathways
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  60. Jul 2023
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    Upregulation of EphA4 deteriorate brain damage by shifting microglia M1-polarization via NF-κB signaling after focal cerebral ischemia in rats
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    Aged/Autoimmune B-cell Program Defines the Early Transformation of Extranodal Lymphomas
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  64. Jun 2023
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    Effects of Dietary Oleacein Treatment on Endothelial Dysfunction and Lupus Nephritis in Balb/C Pristane-Induced Mice
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    The Natural Alkaloid (-)- N-Hydroxyapiosporamide Suppresses Colorectal Tumor Progression as an NF-κB Pathway Inhibitor by Targeting the TAK1-TRAF6 Complex
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  67. www.microbiologyresearch.org www.microbiologyresearch.org
    IRAK1 inhibition blocks the HIV-1 RNA mediated pro-inflammatory cytokine response from microglia
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  68. May 2023
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    Lacking ARHGAP25 mitigates the symptoms of autoantibody-induced arthritis in mice
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  70. Dec 2022
  71. www.karger.com www.karger.com
    Pacritinib Inhibition of IRAK1 Blocks Aberrant TLR8 Signalling by SARS-CoV-2 and HIV-1-Derived RNA
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    Adaptor protein MyD88 confers the susceptibility to stress via amplifying immune danger signals
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  74. Aug 2022
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    The IRAK4 scaffold integrates TLR4-driven TRIF and MYD88 signaling pathways
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  76. Apr 2022
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    Long-term and potent IOP-lowering effect of IκBα-siRNA in a nonhuman primate model of chronic ocular hypertension
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    Atractylenolide III ameliorates spinal cord injury in rats by modulating microglial/macrophage polarization
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    Pharmacological blockade of PCAF ameliorates osteoarthritis development via dual inhibition of TNF-α-driven inflammation and ER stress
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  80. Mar 2022
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bone erosion in inflammatory arthritis is attenuated by Trichinella spiralis through inhibiting M1 monocyte/macrophage polarization
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  82. Jan 2022
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    Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses
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  84. Dec 2021
  85. www.nature.com www.nature.com
    A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of extracellular microRNA-146a-5p in host innate immunity and bacterial sepsis
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  87. Aug 2021
  88. www.cell.com www.cell.com
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  89. Jul 2021
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    Fatty acid receptor GPR120 promotes breast cancer chemoresistance by upregulating ABC transporters expression and fatty acid synthesis
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  91. Apr 2021
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    TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation
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  93. Mar 2021
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  95. Feb 2021
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    Chicoric acid ameliorate inflammation and oxidative stress in Lipopolysaccharide and d‐galactosamine induced acute liver injury
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    Iron Potentiates Microglial Interleukin‐1β Secretion Induced by Amyloid‐β
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  98. Jan 2021
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    Isolation and characterization of extracellular vesicles produced by cell lines
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  100. Oct 2020
  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Non-Transcriptional and Translational Function of Canonical NF-κB Signaling in Activating ERK1/2 in IL-1β-Induced COX-2 Expression in Synovial Fibroblasts
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  102. Sep 2020
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    Threonine ADP-Ribosylation of Ubiquitin by a Bacterial Effector Family Blocks Host Ubiquitination
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    Macrophage K63-Linked Ubiquitination of YAP Promotes Its Nuclear Localization and Exacerbates Atherosclerosis
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  105. Jan 2020
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    Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses
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  108. Nov 2018
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    LncRNA CamK-A Regulates Ca2+-Signaling-Mediated Tumor Microenvironment Remodeling
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  110. Nov 2017
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    Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tat 101-Mediated Enhancement of Brain Pericyte Migration Involves Platelet-Derived Growth Factor Subunit B Homodimer: Implications for Human Immunodeficiency Virus-Associated Neurocognitive Disorders
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