38 Matching Annotations
  1. Sep 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Protein UFMylation regulates early events during ribosomal DNA-damage response
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    1. scibot 17 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114738

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    sciencedirect.com/science/article/pii/S2211124724010891
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    TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
    1
    1. scibot 12 Sep 2024
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      DOI: 10.1016/j.cell.2024.08.020

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    sciencedirect.com/science/article/pii/S0092867424009115
  4. Aug 2024
  5. www.sciencedirect.com www.sciencedirect.com
    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
    1
    1. scibot 23 Aug 2024
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      DOI: 10.1016/j.molcel.2024.08.006

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    sciencedirect.com/science/article/pii/S1097276524006609
  6. May 2024
  7. 52.53.155.43 52.53.155.43
    Deregulation of multiple mechanisms shapes the onset of LAMA2-congenital muscular dystrophy
    1
    1. scibot 03 May 2024
      RRID:AB_10694558

      DOI: 10.1101/2024.01.20.576409

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    52.53.155.43/7b872e2a242fd4fbc3d2b3ce1093dc18df5efbc4/2024.01.20.576409v1.full-html.html
  8. Apr 2024
  9. www.sciencedirect.com www.sciencedirect.com
    DNA-PK and ATM drive phosphorylation signatures that antagonistically regulate cytokine responses to herpesvirus infection or DNA damage
    2
    1. scibot 12 Apr 2024
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      DOI: 10.1016/j.cels.2024.03.003

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    2. scibot 12 Apr 2024
      RRID:AB_10694558

      DOI: 10.1016/j.cels.2024.03.003

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    sciencedirect.com/science/article/pii/S2405471224000887
  10. Dec 2023
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    IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors
    1
    1. scibot 16 Dec 2023
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      DOI: 10.1016/j.molcel.2023.11.022

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    sciencedirect.com/science/article/pii/S109727652300967X
  12. Aug 2023
  13. www.sciencedirect.com www.sciencedirect.com
    Senescent cells form nuclear foci that contain the 26S proteasome
    1
    1. scibot 04 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112880

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    sciencedirect.com/science/article/pii/S2211124723008914
  14. 52.53.155.43 52.53.155.43
    can-22-4017-html.html
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    1. scibot 04 Aug 2023
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      DOI: 10.1158/0008-5472.can-22-4017

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    2. scibot 04 Aug 2023
      RRID:AB_10694558

      DOI: 10.1158/0008-5472.can-22-4017

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    52.53.155.43/9095f2133470165b212e6a97c53f24a603903e15/can-22-4017 (1)-html.html
  15. Jul 2023
  16. www.sciencedirect.com www.sciencedirect.com
    Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer
    1
    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.ccell.2023.06.010

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    sciencedirect.com/science/article/pii/S1535610823002350
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic analysis of the molecular and biophysical properties of key DNA damage response factors
    1
    1. scibot 06 Jul 2023
      RRID:AB_10694558

      DOI: 10.7554/eLife.87086

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    ncbi.nlm.nih.gov/pmc/articles/PMC10319438/
  18. Apr 2023
  19. aacrjournals.org aacrjournals.org
    Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
    1
    1. scibot 21 Apr 2023
      RRID:AB_10694558

      DOI: 10.1158/2326-6066.CIR-22-0056

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    aacrjournals.org/cancerimmunolres/article/11/3/381/716712/Cancer-Cell-Resistance-to-IFN-Can-Occur-via
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-Molecule Polθ Inhibitors Provide Safe and Effective Tumor Radiosensitization in Preclinical Models
    1
    1. scibot 21 Apr 2023
      RRID:AB_10694558

      DOI: 10.1158/1078-0432.CCR-22-2977

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    ncbi.nlm.nih.gov/pmc/articles/PMC10102842/
  21. Feb 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Regulation of DNA damage response by trimeric G-proteins
    1
    1. scibot 09 Feb 2023
      RRID:AB_10694558

      DOI: 10.1016/j.isci.2023.105973

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    ncbi.nlm.nih.gov/pmc/articles/PMC9900518/
  23. www.sciencedirect.com www.sciencedirect.com
    PARylation of BRCA1 limits DNA break resection through BRCA2 and EXO1
    1
    1. scibot 03 Feb 2023
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      DOI: 10.1016/j.celrep.2023.112060

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    sciencedirect.com/science/article/pii/S2211124723000712
  24. Nov 2022
  25. www.sciencedirect.com www.sciencedirect.com
    NEIL3 contributes to the Fanconi anemia/BRCA pathway by promoting the downstream double-strand break repair step
    1
    1. scibot 10 Nov 2022
      RRID:AB_10694558

      DOI: 10.1016/j.celrep.2022.111600

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    sciencedirect.com/science/article/pii/S2211124722014656
  26. www.sciencedirect.com www.sciencedirect.com
    Biosensor Cell-Fit-HD4D for correlation of single-cell fate and microscale energy deposition in complex ion beams
    1
    1. scibot 03 Nov 2022
      RRID:AB_10694558

      DOI: 10.1016/j.xpro.2022.101798

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    sciencedirect.com/science/article/pii/S2666166722006785
  27. Oct 2022
  28. www.nature.com www.nature.com
    C9orf72 functions in the nucleus to regulate DNA damage repair
    1
    1. scibot 12 Oct 2022
      RRID:AB_10694558

      DOI: 10.1038/s41418-022-01074-0

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    nature.com/articles/s41418-022-01074-0
  29. Apr 2022
  30. aacrjournals.org aacrjournals.org
    Loss of Claudin-4 Reduces DNA Damage Repair and Increases Sensitivity to PARP Inhibitors
    1
    1. scibot 09 Apr 2022
      RRID:AB_10694558

      DOI: 10.1158/1535-7163.MCT-21-0827

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    aacrjournals.org/mct/article/21/4/647/689566/Loss-of-Claudin-4-Reduces-DNA-Damage-Repair-and
  31. Mar 2022
  32. www.sciencedirect.com www.sciencedirect.com
    Micropeptide PACMP inhibition elicits synthetic lethal effects by decreasing CtIP and poly(ADP-ribosyl)ation
    1
    1. scibot 02 Mar 2022
      RRID:AB_10694558

      DOI: 10.1016/j.molcel.2022.01.020

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    sciencedirect.com/science/article/pii/S1097276522000855
  33. Feb 2022
  34. www.sciencedirect.com www.sciencedirect.com
    Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity
    1
    1. scibot 23 Feb 2022
      RRID:AB_10694558

      DOI: 10.1016/j.celrep.2022.110422

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    sciencedirect.com/science/article/pii/S2211124722001462
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    Biosensor for deconvolution of individual cell fate in response to ion beam irradiation
    1
    1. scibot 18 Feb 2022
      RRID:AB_10694558

      DOI: 10.1016/j.crmeth.2022.100169

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    sciencedirect.com/science/article/pii/S2667237522000212
  36. Sep 2021
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In situ observation of mitochondrial biogenesis as the early event of apoptosis
    1
    1. scibot 25 Sep 2021
      RRID:AB_10694558

      DOI: 10.1016/j.isci.2021.103038

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    ncbi.nlm.nih.gov/pmc/articles/PMC8441175/
  38. Aug 2021
  39. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 10 Aug 2021
      RRID:AB_10694558

      DOI: 10.1016/j.molcel.2018.10.045

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    sciencedirect.com/science/article/pii/S1097276518309390
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
    1
    1. scibot 02 Aug 2021
      RRID:AB_10694558

      DOI: 10.1016/j.cels.2016.11.013

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    ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
  41. Jul 2021
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
    1
    1. scibot 27 Jul 2021
      RRID: AB_10694558

      DOI: 10.1016/j.cels.2016.11.013

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    ncbi.nlm.nih.gov/pmc/articles/PMC5279869/
  43. May 2021
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation
    1
    1. scibot 26 May 2021
      RRID:AB_10694558

      DOI: 10.1016/j.celrep.2021.109153

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    ncbi.nlm.nih.gov/pmc/articles/PMC8170441/
  45. www.sciencedirect.com www.sciencedirect.com
    Helicobacter pylori CagA elicits BRCAness to induce genome instability that may underlie bacterial gastric carcinogenesis
    1
    1. scibot 14 May 2021
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      DOI: 10.1016/j.chom.2021.04.006

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    sciencedirect.com/science/article/pii/S1931312821001827
  46. www.sciencedirect.com www.sciencedirect.com
    TIRR inhibits the 53BP1-p53 complex to alter cell-fate programs
    1
    1. scibot 09 May 2021
      RRID:AB_10694558

      DOI: 10.1016/j.molcel.2021.03.039

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    sciencedirect.com/science/article/pii/S1097276521002343
  47. Sep 2020
  48. www.sciencedirect.com www.sciencedirect.com
    Cooperation of the ATM and Fanconi Anemia/BRCA Pathways in Double-Strand Break End Resection
    1
    1. scibot 26 Sep 2020
      RRID:AB_10694558

      DOI: 10.1016/j.celrep.2020.01.052

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    sciencedirect.com/science/article/pii/S2211124720300772
  49. academic.oup.com academic.oup.com
    Hedgehog signaling enables repair of ribosomal DNA double-strand breaks
    1
    1. scibot 13 Sep 2020
      53BP1

      DOI: 10.1093/nar/gkaa733

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaa733/5902436
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A high-throughput small molecule screen identifies farrerol as a potentiator of CRISPR/Cas9-mediated genome editing
    1
    1. scibot 05 Sep 2020
      RRID:AB_10694558

      DOI: 10.7554/eLife.56008

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    ncbi.nlm.nih.gov/pmc/articles/PMC7380943/
  51. Jan 2020
  52. www.sciencedirect.com www.sciencedirect.com
    Suppressing Aneuploidy-Associated Phenotypes Improves the Fitness of Trisomy 21 Cells
    1
    1. scibot 13 Jan 2020
      RRID:AB_10694558

      DOI: 10.1016/j.celrep.2019.10.059

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    sciencedirect.com/science/article/pii/S2211124719313737
  53. www.sciencedirect.com www.sciencedirect.com
    RUVBL1/RUVBL2 ATPase Activity Drives PAQosome Maturation, DNA Replication and Radioresistance in Lung Cancer
    1
    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.chembiol.2019.12.005

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    sciencedirect.com/science/article/pii/S2451945619304015
  54. Nov 2018
  55. www.sciencedirect.com www.sciencedirect.com
    BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1535610818300199
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
    1
    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC5926201/
  57. Nov 2017
  58. www.sciencedirect.com www.sciencedirect.com
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
    1
    1. scibot 08 Nov 2017
      AB_10694558

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    sciencedirect.com/science/article/pii/S2405471216304082