39 Matching Annotations
  1. May 2024
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    Macrophage MCT4 inhibition activates reparative genes and protects from atherosclerosis by histone H3 lysine 18 lactylation
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      DOI: 10.1016/j.celrep.2024.114180

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    sciencedirect.com/science/article/pii/S2211124724005084
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    Identification of WNK1 as a therapeutic target to suppress IgH/MYC expression in multiple myeloma
    1
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    sciencedirect.com/science/article/pii/S2211124724005394
  4. Apr 2024
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    Cis-regulatory control of transcriptional timing and noise in response to estrogen
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    ncbi.nlm.nih.gov/pmc/articles/PMC11099348/
  6. Mar 2024
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    Transcription elongation defects link oncogenic SF3B1 mutations to targetable alterations in chromatin landscape
    1
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    sciencedirect.com/science/article/pii/S1097276524001758
  8. Feb 2024
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    Enhancer-promoter activation by the Kaposi sarcoma-associated herpesvirus episome maintenance protein LANA
    1
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    sciencedirect.com/science/article/pii/S221112472400216X
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    EZH2/G9a interact to mediate drug resistance in non-small-cell lung cancer by regulating the SMAD4/ERK/c-Myc signaling axis
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    sciencedirect.com/science/article/pii/S2211124724000421
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    Targeting EMSY-mediated methionine metabolism is a potential therapeutic strategy for triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S2666379124000053
  12. Oct 2023
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    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
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    sciencedirect.com/science/article/pii/S1097276521001775
  14. Jul 2023
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    Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1
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    sciencedirect.com/science/article/pii/S1097276523004306
  16. Apr 2023
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    Genome graphs detect human polymorphisms in active epigenomic state during influenza infection
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    sciencedirect.com/science/article/pii/S2666979X23000605
  18. Dec 2022
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    SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia
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    sciencedirect.com/science/article/pii/S2211124722016059
  20. Sep 2022
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    Targeting histone methylation to reprogram the transcriptional state that drives survival of drug-tolerant myeloid leukemia persisters
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    1. scibot 15 Sep 2022
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  22. Jun 2022
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    Single-cell epigenetic analysis reveals principles of chromatin states in H3.3-K27M gliomas
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    Dynamic Chromatin States Coupling with Key Transcription Factors in Colitis-Associated Colorectal Cancer
    1
    1. scibot 18 Jun 2022
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      DOI: 10.1002/advs.202200536

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    ncbi.nlm.nih.gov/pmc/articles/PMC9376751/
  25. May 2022
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    XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation
    1
    1. scibot 25 May 2022
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      DOI: 10.1016/j.cell.2022.04.034

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    sciencedirect.com/science/article/pii/S0092867422005323
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    KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
    1
    1. scibot 11 May 2022
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    sciencedirect.com/science/article/pii/S2211124722005551
  28. Apr 2022
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    Disease-associated KBTBD4 mutations in medulloblastoma elicit neomorphic ubiquitylation activity to promote CoREST degradation
    1
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      DOI: 10.1038/s41418-022-00983-4

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    nature.com/articles/s41418-022-00983-4
  30. Mar 2022
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    PTIP governs NAD+ metabolism by regulating CD38 expression to drive macrophage inflammation
    1
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      DOI: 10.1016/j.celrep.2022.110603

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    sciencedirect.com/science/article/pii/S2211124722003515
  32. Jan 2022
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    Genome-wide identification of the genetic basis of amyotrophic lateral sclerosis
    1
    1. scibot 19 Jan 2022
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      DOI: 10.1016/j.neuron.2021.12.019

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    sciencedirect.com/science/article/pii/S0896627321010369
  34. Dec 2021
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts
    1
    1. scibot 01 Dec 2021
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      DOI: 10.7554/eLife.67952

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    ncbi.nlm.nih.gov/pmc/articles/PMC8626089/
  36. Nov 2021
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    CUT&Tag-BS for simultaneous profiling of histone modification and DNA methylation with high efficiency and low cost
    1
    1. scibot 16 Nov 2021
      5326S

      DOI: 10.1016/j.crmeth.2021.100118

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    sciencedirect.com/science/article/pii/S266723752100182X
  38. Sep 2021
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    SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
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    1. scibot 28 Sep 2021
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      DOI: 10.1016/j.stem.2021.09.004

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    sciencedirect.com/science/article/pii/S1934590921003805
  40. Jul 2021
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    Establishment, maintenance, and recall of inflammatory memory
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      DOI: 10.1016/j.stem.2021.07.001

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    sciencedirect.com/science/article/pii/S1934590921002861
  42. May 2021
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    Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release
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    sciencedirect.com/science/article/pii/S1097276521001763
  44. Apr 2021
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    Integrated Metabolic and Epigenomic Reprograming by H3K27M Mutations in Diffuse Intrinsic Pontine Gliomas
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      DOI: 10.1016/j.ccell.2020.07.008

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    sciencedirect.com/science/article/pii/S153561082030369X
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    SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy
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      DOI: 10.1016/j.ccell.2020.04.014

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    MLL3 suppresses tumorigenesis through regulating TNS3 enhancer activity
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      DOI: 10.1038/s41419-021-03647-2

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    nature.com/articles/s41419-021-03647-2
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    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
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  49. Sep 2020
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    The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan
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    KMT2D Deficiency Impairs Super-Enhancers to Confer a Glycolytic Vulnerability in Lung Cancer
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    Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells
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    sciencedirect.com/science/article/pii/S1097276520301581
  53. Jan 2020
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    Quantitative Multiplexed ChIP Reveals Global Alterations that Shape Promoter Bivalency in Ground State Embryonic Stem Cells
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      DOI: 10.1016/j.celrep.2019.08.046

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    sciencedirect.com/science/article/pii/S2211124719310940
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    Structural Basis of H2B Ubiquitination-Dependent H3K4 Methylation by COMPASS
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      DOI: 10.1016/j.molcel.2019.10.013

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    A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2
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      DOI: 10.1016/j.celrep.2019.10.011

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    sciencedirect.com/science/article/pii/S2211124719313117
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
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      DOI: 10.7554/eLife.40364

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    ncbi.nlm.nih.gov/pmc/articles/PMC6344081/
  58. Nov 2018
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    Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies
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    sciencedirect.com/science/article/pii/S1097276518306750
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    Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module
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    sciencedirect.com/science/article/pii/S0092867418308067
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    Inhibition of Methyltransferase Setd7 Allows the In Vitro Expansion of Myogenic Stem Cells with Improved Therapeutic Potential
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    sciencedirect.com/science/article/pii/S1934590917305118
  62. Nov 2017
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    ACK1/TNK2 Regulates Histone H4 Tyr88-phosphorylation and AR Gene Expression in Castration-Resistant Prostate Cancer
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      Curator: @chewbeccax

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