36 Matching Annotations
  1. Last 7 days
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    Gut microbiota protect against colorectal tumorigenesis through lncRNA Snhg9
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    1. scibot 07 Jan 2025
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    sciencedirect.com/science/article/pii/S1534580724007342
  3. Dec 2024
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    Commensal papillomavirus immunity preserves the homeostasis of highly mutated normal skin
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    sciencedirect.com/science/article/pii/S1535610824004483
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    Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer
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    1. scibot 03 Dec 2024
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    science.org/doi/10.1126/scisignal.adp1375
  6. Sep 2024
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    Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy
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    1. scibot 10 Sep 2024
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    sciencedirect.com/science/article/pii/S0092867424009048
  8. Jul 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin signaling mediates survival of dormant epithelial ovarian cancer cells
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    1. scibot 20 Jul 2024
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      DOI: 10.7554/eLife.91766

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    ncbi.nlm.nih.gov/pmc/articles/PMC11257678/
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    Pancreatic cancer organoid-screening captures personalized sensitivity and chemoresistance suppression upon CYP3A5-targeted inhibition
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    sciencedirect.com/science/article/pii/S2589004224015141
  11. May 2024
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    Targeting WEE1 enhances the antitumor effect of KRAS-mutated non-small cell lung cancer harboring TP53 mutations
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    1. scibot 23 May 2024
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    sciencedirect.com/science/article/pii/S2666379124002702
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    CDK4/6 activity is required during G2 arrest to prevent stress-induced endoreplication
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    1. scibot 03 May 2024
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      DOI: 10.1126/science.adi2421

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  14. Apr 2024
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    DUX4-induced HSATII transcription causes KDM2A/B-PRC1 nuclear foci and impairs DNA damage response
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    1. scibot 25 Apr 2024
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      DOI: 10.1083/jcb.202303141

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    rupress.org/jcb/article/223/5/e202303141/276604/DUX4-induced-HSATII-transcription-causes-KDM2A-B
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    Sustained ERK signaling promotes G2 cell cycle exit and primes cells for whole-genome duplication
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    1. scibot 20 Apr 2024
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    CircTMEM165 facilitates endothelial repair by modulating mitochondrial fission via miR-192/SCP2 in vitro and in vivo
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    1. scibot 10 Apr 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11000015/
  18. Mar 2024
  19. www.nature.com www.nature.com
    Light-mediated intracellular polymerization
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    1. scibot 26 Mar 2024
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      DOI: 10.1038/s41596-024-00970-8

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  20. Feb 2024
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    Fluoroquinolones upregulate insulin-like growth factor–binding protein 3, inhibit cell growth and insulin-like growth factor signaling
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      AB_10

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    sciencedirect.com/science/article/pii/S0014299924001092
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    Akt3 activation by R-Ras in an endothelial cell enforces quiescence and barrier stability of neighboring endothelial cells via Jagged1
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    1. scibot 27 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001657
  23. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    p63 controls metabolic activation of hepatic stellate cells and fibrosis via an HER2-ACC1 pathway
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  24. Dec 2023
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    Bi-allelic variants in CEP295 cause Seckel-like syndrome presenting with primary microcephaly, developmental delay, intellectual disability, short stature, craniofacial and digital abnormalities
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  26. Aug 2023
  27. 52.53.155.43 52.53.155.43
    PIIS2589004223016784-html.html
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      RRID:AB_106958

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  28. 52.53.155.43 52.53.155.43
    Nuclear transport surveillance of p53 by nuclear pores in glioblastoma
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    1. scibot 12 Aug 2023
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  29. Mar 2023
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    Multiplex imaging of breast cancer lymph node metastases identifies prognostic single-cell populations independent of clinical classifiers
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    sciencedirect.com/science/article/pii/S2666379123000836
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual IKZF2 and CK1α degrader targets acute myeloid leukemia cells
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    1. scibot 10 Mar 2023
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      DOI: 10.1016/j.ccell.2023.02.010

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    ncbi.nlm.nih.gov/pmc/articles/PMC10466730/
  32. Feb 2023
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    Numb/Parkin-directed mitochondrial fitness governs cancer cell fate via metabolic regulation of histone lactylation
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      DOI: 10.1016/j.celrep.2023.112033

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    sciencedirect.com/science/article/pii/S221112472300044X
  34. Jan 2023
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    A p53-TLR3 axis ameliorates pulmonary hypertension by inducing BMPR2 via IRF3
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      DOI: 10.1016/j.isci.2023.105935

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    sciencedirect.com/science/article/pii/S2589004223000123
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    Targeting KRAS-mutant stomach/colorectal tumors by disrupting the ERK2-p53 complex
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      DOI: 10.1016/j.celrep.2022.111972

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    sciencedirect.com/science/article/pii/S2211124722018769
  37. Nov 2022
  38. link.springer.com link.springer.com
    ΔNp63α transcriptionally represses p53 target genes involved in the radiation-induced DNA damage response
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      DOI: 10.1186/s13014-022-02139-7

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    link.springer.com/article/10.1186/s13014-022-02139-7
  39. Oct 2022
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    Validation of a non-oncogene encoded vulnerability to exportin 1 inhibition in pediatric renal tumors
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    1. scibot 04 Oct 2022
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      DOI: 10.1016/j.medj.2022.09.002

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    sciencedirect.com/science/article/pii/S2666634022004032
  41. Jun 2022
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    Poroptosis: a form of cell death depending on plasma membrane nanopores formation
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    1. scibot 15 Jun 2022
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    sciencedirect.com/science/article/pii/S2589004222007520
  43. Jul 2021
  44. elifesciences.org elifesciences.org
    Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy
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    1. scibot 31 Jul 2021
      RRID:AB_10695803

      DOI: 10.7554/eLife.27301

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    elifesciences.org/articles/27301
  45. Apr 2021
  46. www.sciencedirect.com www.sciencedirect.com
    p53 is a central regulator driving neurodegeneration caused by C9orf72 poly(PR)
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    1. scibot 24 Apr 2021
      RRID:AB_10695803

      DOI: 10.1016/j.cell.2020.12.025

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    sciencedirect.com/science/article/pii/S0092867420317475
  47. Jan 2021
  48. link.springer.com link.springer.com
    A novel ligand of the translationally controlled tumor protein (TCTP) identified by virtual drug screening for cancer differentiation therapy
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    1. scibot 28 Jan 2021
      RRID:AB_10695803

      DOI: 10.1007/s10637-020-01042-w

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    link.springer.com/article/10.1007/s10637-020-01042-w
  49. Dec 2020
  50. www.sciencedirect.com www.sciencedirect.com
    Gain-of-function hot spot mutant p53R248Q regulation of integrin/FAK/ERK signaling in esophageal squamous cell carcinoma
    1
    1. scibot 15 Dec 2020
      p53

      DOI: 10.1016/j.tranon.2020.100982

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    sciencedirect.com/science/article/pii/S1936523320304745
  51. Sep 2020
  52. www.cell.com www.cell.com
    Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains
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      RRID:AB_331211

      DOI: 10.1016/j.molcel.2018.11.006

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    cell.com/molecular-cell/abstract/S1097-2765(18)30948-1
  53. Jan 2020
  54. academic.oup.com academic.oup.com
    Synergistic Highly Potent Targeted Drug Combinations in different Pheochromocytoma Models including Human Tumor Cultures
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      RRID:AB_10695803

      DOI: 10.1210/en.2019-00410

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    academic.oup.com/endo/article/160/11/2600/5535649
  55. Nov 2018
  56. www.sciencedirect.com www.sciencedirect.com
    Integrated analysis of DNA methylome and transcriptome identified CREB5 as a novel risk gene contributing to recurrent pregnancy loss
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    sciencedirect.com/science/article/pii/S2352396418302846
  57. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    sciencedirect.com/science/article/pii/S2211124718310362