132 Matching Annotations
  1. May 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Triptolide enhances anti-cancer activities of irinotecan in human colon cancer HT-29 cells in vitro and HT-29 cell xenograft tumor model in nude mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC13201951/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13130659/
  4. Apr 2026
  5. 54.241.53.176 54.241.53.176
    2026.04.20.719456.full-html.html
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    54.241.53.176/6790efd246ed84de929dd028ff8d6465bfa7b2e6/2026.04.20.719456.full-html.html
  6. Mar 2026
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A preclinical candidate of cyclophilin D inhibition improves alcohol-associated liver injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC13006403/
  8. Feb 2026
  9. 54.241.53.176 54.241.53.176
    1-s2.0-S2589004226004281-main-html.html
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    54.241.53.176/d87d0757cb2189057ec92a05486ad0d385992a97/1-s2.0-S2589004226004281-main-html.html
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Raspberry Polyphenols Target Molecular Pathways of Heart Failure
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    pmc.ncbi.nlm.nih.gov/articles/PMC12862629/
  11. Jan 2026
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDK4/6 inhibition overcomes venetoclax resistance mechanisms with enhanced combination activity in acute myeloid leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12866115/
  13. Dec 2025
  14. www.sciencedirect.com www.sciencedirect.com
    A 3D in vitro model for studying human implantation and implantation failure
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    sciencedirect.com/science/article/pii/S0092867425012309
  15. Oct 2025
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cardiomyocyte-specific LARP6 overexpression prevents angiotensin II-induced myocardial dysfunction and interstitial fibrosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12482548/
  17. Aug 2025
  18. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225016840-main-html.html
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    52.53.155.43/23fa3039143e04e3669aa6d24e522324d4b71ce2/1-s2.0-S2589004225016840-main-html.html
  19. 52.53.155.43 52.53.155.43
    russell-et-al-2025-cardiomyocyte-specific-larp6-overexpression-prevents-angiotensin-ii-induced-myocardial-dysfunction-html.html
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    52.53.155.43/cdc89213e8da95a53f691c27b85c44a7e3f558a7/russell-et-al-2025-cardiomyocyte-specific-larp6-overexpression-prevents-angiotensin-ii-induced-myocardial-dysfunction-html.html
  20. Jul 2025
  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Uric Acid Causes Pancreatic β Cell Death and Dysfunction via Modulating CHOP-Mediated Endoplasmic Reticulum Stress Pathways
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    pmc.ncbi.nlm.nih.gov/articles/PMC12293447/
  22. www.biorxiv.org www.biorxiv.org
    Paclitaxel-induced mitotic arrest results in a convergence of apoptotic dependencies that can be safely exploited by BCL-XL degradation to overcome cancer chemoresistance
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    biorxiv.org/content/10.1101/2025.06.24.661170v1
  23. Jun 2025
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cisplatin-Induced APE2 Overexpression Disrupts MYH9 Function and Causes Hearing Loss
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    pmc.ncbi.nlm.nih.gov/articles/PMC12179588/
  25. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mechanistic Understanding of Dexamethasone-Mediated Protection against Remdesivir-Induced Hepatotoxicity
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    pmc.ncbi.nlm.nih.gov/articles/PMC12164689/
  26. 52.53.155.43 52.53.155.43
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    52.53.155.43/0dae8a278297c88adbf334a09a65a2e37332ee1c/PDF-html.html
  27. 52.53.155.43 52.53.155.43
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  29. May 2025
  30. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004225008454-main-html.html
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  31. Apr 2025
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced Apoptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11964295/
  33. Mar 2025
  34. www.sciencedirect.com www.sciencedirect.com
    The actin and microtubule network regulator WHAMM is identified as a key kidney disease risk gene
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    sciencedirect.com/science/article/pii/S2211124725002335
  35. www.sciencedirect.com www.sciencedirect.com
    Unveiling ODP4: A breakthrough in PCOS treatment via BAT transplantation
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    sciencedirect.com/science/article/pii/S0006295225001339
  36. Feb 2025
  37. 52.53.155.43 52.53.155.43
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  38. www.sciencedirect.com www.sciencedirect.com
    Microglial pyroptosis drives neuropathic pain and targeting NLRP3 alleviates pain and neuroinflammation
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    sciencedirect.com/science/article/pii/S0925443925000821
  39. 52.53.155.43 52.53.155.43
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  40. Dec 2024
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Slc25a21 in cisplatin-induced acute kidney injury: a new target for renal tubular epithelial protection by regulating mitochondrial metabolic homeostasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11655545/
  42. Aug 2024
  43. www.sciencedirect.com www.sciencedirect.com
    Chinese medicine Linggui Zhugan formula protects against diabetic kidney disease in close association with inhibition of proteinase 3-mediated podocyte apoptosis in mice
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    sciencedirect.com/science/article/pii/S0378874124009498
  44. www.mdpi.com www.mdpi.com
    Ellagic Acid Prevents α-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated α-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy
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    mdpi.com/1422-0067/22/24/13398/htm
  45. Jun 2024
  46. www.cell.com www.cell.com
    Oxygen tension-dependent variability in the cancer cell kinome impacts signaling pathways and response to targeted therapies
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    cell.com/iscience/abstract/S2589-0042(24)01293-8
  47. www.sciencedirect.com www.sciencedirect.com
    Monomethyl fumarate attenuates lung Ischemia/Reperfusion injury by disrupting the GAPDH/Siah1 signaling cascade
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    sciencedirect.com/science/article/pii/S1567576924010099
  48. www.sciencedirect.com www.sciencedirect.com
    MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels
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    sciencedirect.com/science/article/pii/S0092867424005269
  49. May 2024
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ganoderma lucidum extract attenuates corticotropin-releasing hormone induced cellular senescence in human hair follicle cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11068553/
  51. Apr 2024
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antitumor effects of a novel photosensitizer-mediated photodynamic therapy and its influence on the cell transcriptome
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    ncbi.nlm.nih.gov/pmc/articles/PMC11055994/
  53. Mar 2024
  54. www.sciencedirect.com www.sciencedirect.com
    Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1
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    sciencedirect.com/science/article/pii/S109727652400176X
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury
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    pmc.ncbi.nlm.nih.gov/articles/PMC10925443/
  56. Feb 2024
  57. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
  58. link.springer.com link.springer.com
    CircUSP1 as a novel marker promotes gastric cancer progression via stabilizing HuR to upregulate USP1 and Vimentin
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    link.springer.com/article/10.1038/s41388-024-02968-8
  59. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16283
  60. www.mdpi.com www.mdpi.com
    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
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    mdpi.com/1467-3045/45/12/620
  61. 52.53.155.43 52.53.155.43
    YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia
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    52.53.155.43/3b983d9532a50e2ebeba730d1190ef88722ceb9a/PIIS2589004224003468-html.html
  62. Jan 2024
  63. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
  64. Nov 2023
  65. www.sciencedirect.com www.sciencedirect.com
    Lidocaine induces apoptosis in head and neck squamous cell carcinoma through activation of bitter taste receptor T2R14
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    sciencedirect.com/science/article/pii/S2211124723014493
  66. Oct 2023
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
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    ncbi.nlm.nih.gov/pmc/articles/PMC10570680/
  68. Sep 2023
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALKBH5-mediated m6A modification of HS3ST3B1-IT1 prevents osteoarthritis progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10518728/
  70. www.nature.com www.nature.com
    Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
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    nature.com/articles/s41422-023-00874-4
  71. www.embopress.org www.embopress.org
    CCDC50 promotes tumor growth through regulation of lysosome homeostasis
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    embopress.org/doi/full/10.15252/embr.202356948
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    URAT1 is expressed in cardiomyocytes and dotinurad attenuates the development of diet-induced metabolic heart disease.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10483053/
  73. Aug 2023
  74. 52.53.155.43 52.53.155.43
    PIIS2211124723009543-html.html
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  75. Jun 2023
  76. www.sciencedirect.com www.sciencedirect.com
    METTL3-mediated m6A modification of IGFBP7-OT promotes osteoarthritis progression by regulating the DNMT1/DNMT3a-IGFBP7 axis
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    sciencedirect.com/science/article/pii/S2211124723006009
  77. Apr 2023
  78. www.sciencedirect.com www.sciencedirect.com
    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
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    sciencedirect.com/science/article/pii/S2666379123001179
  79. Mar 2023
  80. 52.53.155.43 52.53.155.43
    A high-sucrose diet exacerbates the left ventricular phenotype in a high fat-fed streptozotocin rat model of diabetic cardiomyopathy
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    52.53.155.43/a2856e34c76df1f90e78f95405a1557ff7dcdfbe/ajpheart.00390.2022-html.html
  81. www.sciencedirect.com www.sciencedirect.com
    FAM193A is a positive regulator of p53 activity
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    sciencedirect.com/science/article/pii/S2211124723002413
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Echinocystic acid alleviated hypoxic-ischemic brain damage in neonatal mice by activating the PI3K/Akt/Nrf2 signaling pathway
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    ncbi.nlm.nih.gov/pmc/articles/PMC9947717/
  83. Feb 2023
  84. www.sciencedirect.com www.sciencedirect.com
    Cationic amphiphilic antihistamines inhibit STAT3 via Ca2+-dependent lysosomal H+ efflux
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    sciencedirect.com/science/article/pii/S2211124723001481
  85. Jan 2023
  86. www.sciencedirect.com www.sciencedirect.com
    Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization
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    sciencedirect.com/science/article/pii/S0969212623000011
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Argon preconditioning protects neuronal cells with a Toll-like receptor-mediated effect
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    ncbi.nlm.nih.gov/pmc/articles/PMC9838174/
  88. Dec 2022
  89. www.mdpi.com www.mdpi.com
    Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines
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    mdpi.com/2072-6643/14/24/5265
  90. 52.53.155.43 52.53.155.43
    Selaginella tamariscina Inhibits Glutamate-Induced Autophagic Cell Death by Activating the PI3K/AKT/mTOR Signaling Pathways
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    52.53.155.43/eb3e7bd6fec17f8c00ac186e434aef30e82c163b/ijms-23-11445-html.html
  91. www.mdpi.com www.mdpi.com
    The Neuroprotective Effects of Arecae Pericarpium against Glutamate-Induced HT22 Cell Cytotoxicity
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    mdpi.com/1467-3045/44/12/402
  92. Nov 2022
  93. www.embopress.org www.embopress.org
    LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus
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    embopress.org/doi/10.15252/embj.2022112006
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9648413/
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
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    ncbi.nlm.nih.gov/pmc/articles/PMC9663903/
  96. Oct 2022
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Schwann cells-derived exosomal miR-21 participates in high glucose regulation of neurite outgrowth
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    ncbi.nlm.nih.gov/pmc/articles/PMC9529988/
  98. Sep 2022
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small molecule SJ572946 activates BAK to initiate apoptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9485059/
  100. www.tandfonline.com www.tandfonline.com
    Lack of COL6/collagen VI causes megakaryocyte dysfunction by impairing autophagy and inducing apoptosis
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    tandfonline.com/doi/abs/10.1080/15548627.2022.2100105
  101. www.sciencedirect.com www.sciencedirect.com
    Sublethal cytochrome c release generates drug-tolerant persister cells
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    sciencedirect.com/science/article/pii/S0092867422009783
  102. Aug 2022
  103. www.sciencedirect.com www.sciencedirect.com
    Analysis of neuroendocrine clones in NSCLCs using an immuno-guided laser-capture microdissection-based approach
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    sciencedirect.com/science/article/pii/S2667237522001485
  104. Jul 2022
  105. aacrjournals.org aacrjournals.org
    Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
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    aacrjournals.org/cancerrescommun/article/2/7/679/707059/Bcl-xL-Inhibition-Radiosensitizes-PIK3CA-PTEN-Wild
  106. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2022 - Li - Maresin 1 intervention Reverses Experimental Pulmonary Arterial Hypertension in mice-html.html
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    52.53.155.43/eeb521b7ce9ed18aede2526ed77220c5d9e406f5/British J Pharmacology - 2022 - Li - Maresin 1 intervention Reverses Experimental Pulmonary Arterial Hypertension in mice-html.html
  107. Jun 2022
  108. www.sciencedirect.com www.sciencedirect.com
    Regulating DNA methylation could reduce neuronal ischemia response and apoptosis after ischemia-reperfusion injury
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    sciencedirect.com/science/article/pii/S037811192200508X
  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intermittent Theta Burst Stimulation Ameliorates Cognitive Deficit and Attenuates Neuroinflammation via PI3K/Akt/mTOR Signaling Pathway in Alzheimer’s-Like Disease Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC9152158/
  110. academic.oup.com academic.oup.com
    Jumonji domain-containing protein-3 (JMJD3/Kdm6b) is critical for normal ovarian function and female fertility
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    academic.oup.com/endo/article-abstract/163/5/bqac047/6565906
  111. May 2022
  112. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta-TC-6 cells via the generation of intracellular reactive oxygen species and mitochondrial superoxide
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    onlinelibrary.wiley.com/doi/10.1002/jbt.23099
  113. Apr 2022
  114. www.nature.com www.nature.com
    Targeting the miR-34a/LRPPRC/MDR1 axis collapse the chemoresistance in P53 inactive colorectal cancer
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    nature.com/articles/s41418-022-01007-x
  115. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15837
  116. www.sciencedirect.com www.sciencedirect.com
    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
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    sciencedirect.com/science/article/pii/S0092867422003403
  117. Mar 2022
  118. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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    elifesciences.org/articles/73150
  119. Feb 2022
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