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    Slc25a21 in cisplatin-induced acute kidney injury: a new target for renal tubular epithelial protection by regulating mitochondrial metabolic homeostasis
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  3. Aug 2024
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    Chinese medicine Linggui Zhugan formula protects against diabetic kidney disease in close association with inhibition of proteinase 3-mediated podocyte apoptosis in mice
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    Ellagic Acid Prevents α-Synuclein Aggregation and Protects SH-SY5Y Cells from Aggregated α-Synuclein-Induced Toxicity via Suppression of Apoptosis and Activation of Autophagy
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  6. Jun 2024
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    Oxygen tension-dependent variability in the cancer cell kinome impacts signaling pathways and response to targeted therapies
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    Monomethyl fumarate attenuates lung Ischemia/Reperfusion injury by disrupting the GAPDH/Siah1 signaling cascade
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    MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels
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  10. May 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ganoderma lucidum extract attenuates corticotropin-releasing hormone induced cellular senescence in human hair follicle cells
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  12. Apr 2024
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    Antitumor effects of a novel photosensitizer-mediated photodynamic therapy and its influence on the cell transcriptome
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  14. Mar 2024
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    Anti-apoptotic MCL-1 promotes long-chain fatty acid oxidation through interaction with ACSL1
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    The BMAL1/HIF2A heterodimer modulates circadian variations of myocardial injury
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  17. Feb 2024
  18. aacrjournals.org aacrjournals.org
    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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    aacrjournals.org/cancerrescommun/article/4/1/5/732220/Inhibition-of-PRL2-Upregulates-PTEN-and-Attenuates
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    CircUSP1 as a novel marker promotes gastric cancer progression via stabilizing HuR to upregulate USP1 and Vimentin
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    Lumbricus Extract Prevents LPS-Induced Inflammatory Activation of BV2 Microglia and Glutamate-Induced Hippocampal HT22 Cell Death by Suppressing MAPK/NF-κB/NLRP3 Signaling and Oxidative Stress
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    YAP-mediated GPER signaling impedes proliferation and survival of prostate epithelium in benign prostatic hyperplasia
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  23. Jan 2024
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    Inhibition of PRL2 upregulates PTEN and attenuates tumor growth in Tp53-deficient sarcoma and lymphoma mouse models
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  25. Nov 2023
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    Lidocaine induces apoptosis in head and neck squamous cell carcinoma through activation of bitter taste receptor T2R14
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  27. Oct 2023
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radiotherapy-Induced Neurocognitive Impairment Is Driven by Heightened Apoptotic Priming in Early Life and Prevented by Blocking BAX
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  29. Sep 2023
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALKBH5-mediated m6A modification of HS3ST3B1-IT1 prevents osteoarthritis progression
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    Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
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  32. www.embopress.org www.embopress.org
    CCDC50 promotes tumor growth through regulation of lysosome homeostasis
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    URAT1 is expressed in cardiomyocytes and dotinurad attenuates the development of diet-induced metabolic heart disease.
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  34. Aug 2023
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  36. Jun 2023
  37. www.sciencedirect.com www.sciencedirect.com
    METTL3-mediated m6A modification of IGFBP7-OT promotes osteoarthritis progression by regulating the DNMT1/DNMT3a-IGFBP7 axis
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  38. Apr 2023
  39. www.sciencedirect.com www.sciencedirect.com
    USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities
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  40. Mar 2023
  41. 52.53.155.43 52.53.155.43
    A high-sucrose diet exacerbates the left ventricular phenotype in a high fat-fed streptozotocin rat model of diabetic cardiomyopathy
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      DOI: 10.1152/ajpheart.00390.2022

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    FAM193A is a positive regulator of p53 activity
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  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Echinocystic acid alleviated hypoxic-ischemic brain damage in neonatal mice by activating the PI3K/Akt/Nrf2 signaling pathway
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      DOI: 10.3389/fphar.2023.1103265

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  44. Feb 2023
  45. www.sciencedirect.com www.sciencedirect.com
    Cationic amphiphilic antihistamines inhibit STAT3 via Ca2+-dependent lysosomal H+ efflux
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  46. Jan 2023
  47. www.sciencedirect.com www.sciencedirect.com
    Peptides from human BNIP5 and PXT1 and non-native binders of pro-apoptotic BAK can directly activate or inhibit BAK-mediated membrane permeabilization
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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Argon preconditioning protects neuronal cells with a Toll-like receptor-mediated effect
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      DOI: 10.4103/1673-5374.355978

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    ncbi.nlm.nih.gov/pmc/articles/PMC9838174/
  49. Dec 2022
  50. www.mdpi.com www.mdpi.com
    Neuroprotective and Anti-Neuroinflammatory Properties of Vignae Radiatae Semen in Neuronal HT22 and Microglial BV2 Cell Lines
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  51. 52.53.155.43 52.53.155.43
    Selaginella tamariscina Inhibits Glutamate-Induced Autophagic Cell Death by Activating the PI3K/AKT/mTOR Signaling Pathways
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      DOI: 10.3390/ijms231911445

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  52. www.mdpi.com www.mdpi.com
    The Neuroprotective Effects of Arecae Pericarpium against Glutamate-Induced HT22 Cell Cytotoxicity
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  53. Nov 2022
  54. www.embopress.org www.embopress.org
    LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus
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      DOI: 10.15252/embj.2022112006

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  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
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  57. Oct 2022
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  59. Sep 2022
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    Small molecule SJ572946 activates BAK to initiate apoptosis
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  63. Aug 2022
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  65. Jul 2022
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    Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
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    British J Pharmacology - 2022 - Li - Maresin 1 intervention Reverses Experimental Pulmonary Arterial Hypertension in mice-html.html
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  68. Jun 2022
  69. www.sciencedirect.com www.sciencedirect.com
    Regulating DNA methylation could reduce neuronal ischemia response and apoptosis after ischemia-reperfusion injury
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    Intermittent Theta Burst Stimulation Ameliorates Cognitive Deficit and Attenuates Neuroinflammation via PI3K/Akt/mTOR Signaling Pathway in Alzheimer’s-Like Disease Model
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    Jumonji domain-containing protein-3 (JMJD3/Kdm6b) is critical for normal ovarian function and female fertility
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  72. May 2022
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    Low concentrations of bisphenol A promote the activation of the mitochondrial apoptotic pathway on Beta-TC-6 cells via the generation of intracellular reactive oxygen species and mitochondrial superoxide
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  74. Apr 2022
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    Targeting the miR-34a/LRPPRC/MDR1 axis collapse the chemoresistance in P53 inactive colorectal cancer
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    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
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  78. Mar 2022
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    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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  80. Feb 2022
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    The interplay between BAX and BAK tunes apoptotic pore growth to control mitochondrial-DNA-mediated inflammation
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  82. Jan 2022
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    Acetyl-CoA production by specific metabolites promotes cardiac repair after myocardial infarction via histone acetylation
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  84. Dec 2021
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  86. Nov 2021
  87. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer
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    SLFN11 is Widely Expressed in Pediatric Sarcoma and Induces Variable Sensitization to Replicative Stress Caused By DNA-Damaging Agents
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    TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change
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    Pharmacological inhibition of arachidonate 12-lipoxygenase ameliorates myocardial ischemia-reperfusion injury in multiple species
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  95. Aug 2021
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    Targeting Aurora B kinase prevents and overcomes resistance to EGFR inhibitors in lung cancer by enhancing BIM- and PUMA-mediated apoptosis
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  100. Jul 2021
  101. elifesciences.org elifesciences.org
    Caspase-mediated cleavage of IRE1 controls apoptotic cell commitment during endoplasmic reticulum stress
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    Andrographolide alleviates parkinsonism in MPTP‐PD mice via targeting DRP1‐mediated mitochondrial fission
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  104. Jun 2021
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  106. May 2021
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  108. Apr 2021
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    Reduced Mitochondrial Apoptotic Priming Drives Resistance to BH3 Mimetics in Acute Myeloid Leukemia
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    MAX Functions as a Tumor Suppressor and Rewires Metabolism in Small Cell Lung Cancer
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  111. Feb 2021
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    Arsenic Trioxide Rescues Structural p53 Mutations through a Cryptic Allosteric Site
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    Alteration of mRNA 5-Methylcytosine Modification in Neurons After OGD/R and Potential Roles in Cell Stress Response and Apoptosis
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    p75NTR Promotes Astrocyte Proliferation in Response to Cortical Stab Wound
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    link.springer.com/article/10.1007/s10571-020-01006-x
  116. Sep 2020
  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531
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      DOI: 10.7554/eLife.56913

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  118. www.sciencedirect.com www.sciencedirect.com
    Inhibition of MEK1/2 Forestalls the Onset of Acquired Resistance to Entrectinib in Multiple Models of NTRK1-Driven Cancer
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      DOI: 10.1016/j.celrep.2020.107994

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  119. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.14959

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  120. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Occludin degradation makes brain microvascular endothelial cells more vulnerable to reperfusion injury in vitro
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      DOI: 10.1111/jnc.15102

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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells
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      DOI: 10.1038/s41419-020-2589-7

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  122. www.tandfonline.com www.tandfonline.com
    Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2
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      DOI: 10.1080/01616412.2020.1735817

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  123. www.tandfonline.com www.tandfonline.com
    Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2
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      RRID:AB_10695870

      DOI: 10.1080/01616412.2020.1735817

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  124. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Platelet CLEC‐2 regulates neuroinflammation and restores blood brain barrier integrity in a mouse model of traumatic brain injury
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      Bax antibody

      DOI: 10.1111/jnc.14983

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  125. www.tandfonline.com www.tandfonline.com
    Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2
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      RRID:AB_10695870

      DOI: 10.1080/01616412.2020.1735817

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  126. www.tandfonline.com www.tandfonline.com
    Nicotine-induced upregulation of miR-132-5p enhances cell survival in PC12 cells by targeting the anti-apoptotic protein Bcl-2
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      RRID:AB_10695870

      DOI: 10.1080/01616412.2020.1735817

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  127. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sirtuin 3 is required for the protective effect of Resveratrol on Manganese‐induced disruption of mitochondrial biogenesis in primary cultured neurons
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      RRID:AB_10695870

      DOI: 10.1111/jnc.15095

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  128. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      AB_10695870

      DOI: 10.1111/bph.14998

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  129. Jan 2020
  130. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Murine maternal dietary restriction affects neural Humanin expression and cellular profile
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      DOI: 10.1002/jnr.24568

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    onlinelibrary.wiley.com/doi/10.1002/jnr.24568
  131. journals.plos.org journals.plos.org
    Isoflurane mediated neuropathological and cognitive impairments in the triple transgenic Alzheimer’s mouse model are associated with hippocampal synaptic deficits in an age-dependent manner
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      RRID:AB_329921

      DOI: 10.1371/journal.pone.0223509

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  132. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Lactoferrin protects against iron dysregulation, oxidative stress, and apoptosis in MPTP‐induced Parkinson's disease in mice
    1
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      DOI: 10.1111/jnc.14857

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  133. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial Reprogramming Underlies Resistance to BCL-2 Inhibition in Lymphoid Malignancies
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      RRID:AB_10695870

      DOI: 10.1016/j.ccell.2019.08.005

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    sciencedirect.com/science/article/pii/S1535610819303733
  134. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      RRID:AB_10695870

      DOI: 10.1111/bph.14706

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    bpspubs.onlinelibrary.wiley.com/doi/abs/10.1111/bph.14706
  135. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Untitled document
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      RRID:AB_10695870

      DOI: 10.1111/bph.14626

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  136. www.sciencedirect.com www.sciencedirect.com
    BCL2 Amplicon Loss and Transcriptional Remodeling Drives ABT-199 Resistance in B Cell Lymphoma Models
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    1. scibot 13 Jan 2020
      RRID:AB_10695870

      DOI: 10.1016/j.ccell.2019.04.005

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    sciencedirect.com/science/article/pii/S1535610819302004
  137. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      RRID:AB_10695870

      DOI: 10.1016/j.celrep.2019.02.076

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    sciencedirect.com/science/article/pii/S2211124719302621
  138. link.springer.com link.springer.com
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      RRID:AB_10695870

      DOI: 10.1007/s12640-018-9991-2

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    link.springer.com/article/10.1007/s12640-018-9991-2
  139. Nov 2018
  140. www.sciencedirect.com www.sciencedirect.com
    Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM
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    sciencedirect.com/science/article/pii/S0896627318307839
  141. content.iospress.com content.iospress.com
    NO-Dependent Akt Inactivation by S-Nitrosylation as a Possible Mechanism of STZ-Induced Neuronal Insulin Resistance
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  142. www.sciencedirect.com www.sciencedirect.com
    Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
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  144. www.sciencedirect.com www.sciencedirect.com
    Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration
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      Curator: @anp055

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  145. Nov 2017
  146. academic.oup.com academic.oup.com
    Gonadotropin-Dependent Neuregulin-1 Signaling Regulates Female Rat Ovarian Granulosa Cell Survival
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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  148. academic.oup.com academic.oup.com
    Gestational Diabetes Alters Functions in Offspring’s Umbilical Cord Cells With Implications for Cardiovascular Health
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      AB_10695870

      Curator: @chewbeccax

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  149. www.sciencedirect.com www.sciencedirect.com
    Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling
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