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Tuning insulin receptor signaling using de novo-designed agonists

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1. scibot 15 Oct 2025
  
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  DOI: 10.1016/j.molcel.2025.09.020
  
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sciencedirect.com/science/article/pii/S1097276525007804
Jul 2025
www.biorxiv.org www.biorxiv.org

Parkinson’s disease microglia induce endogenous α-synuclein pathology in patient-specific midbrain organoids

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1. scibot 08 Jul 2025
  
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  DOI: 10.1101/2025.07.01.662685
  
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biorxiv.org/content/10.1101/2025.07.01.662685v1
Apr 2025
52.53.155.43 52.53.155.43

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1. scibot 02 Apr 2025
  
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  DOI: 10.1101/2025.03.28.645939
  
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52.53.155.43/d92b011119470b2ed58da6e2cdd0541e039e2530/PDF-html.html
Mar 2025
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Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.molcel.2025.03.001
  
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sciencedirect.com/science/article/pii/S1097276525001947
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The actin and microtubule network regulator WHAMM is identified as a key kidney disease risk gene

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1. scibot 29 Mar 2025
  
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  DOI: 10.1016/j.celrep.2025.115462
  
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sciencedirect.com/science/article/pii/S2211124725002335
52.53.155.43 52.53.155.43

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1. scibot 14 Mar 2025
  
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  DOI: 10.1101/2025.03.05.639198
  
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52.53.155.43/6a1077851a93128037200ab8bc35f1d4060f0db6/PDF-html.html
Feb 2025
dx.doi.org dx.doi.org

The roles of Growth Hormone dependent JAK-STAT5 and Lyn kinase signalling in determining lifespan and cancer incidence

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1. scibot 20 Feb 2025
  
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  DOI: 10.1210/endocr/bqae136
  
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dx.doi.org/10.1210/endocr/bqae136
Jan 2025
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The human zinc-binding cysteine proteome

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1. scibot 03 Jan 2025
  
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  DOI: 10.1016/j.cell.2024.11.025
  
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sciencedirect.com/science/article/pii/S0092867424013412
Jan 2024
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Atrial natriuretic peptide signaling co-regulates lipid metabolism and ventricular conduction system gene expression in the embryonic heart

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1. scibot 20 Jan 2024
  
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  DOI: 10.1016/j.isci.2023.108748
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10792247/
Sep 2023
journals.asm.org journals.asm.org

Nectin-3 and shed forms of CSPG4 can serve as epithelial cell receptors for Clostridioides difficile TcdB

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1. scibot 30 Sep 2023
  
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  RRID:AB_10696895
  
  DOI: 10.1128/mbio.01857-23
  
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journals.asm.org/doi/10.1128/mbio.01857-23
Jul 2023
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Super-resolution imaging unveils the self-replication of tau aggregates upon seeding

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1. scibot 05 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112725
  
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sciencedirect.com/science/article/pii/S2211124723007362
Dec 2022
link.springer.com link.springer.com

AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer

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1. scibot 20 Dec 2022
  
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  DOI: 10.1007/s00018-022-04638-y
  
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link.springer.com/article/10.1007/s00018-022-04638-y
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

STAG2 promotes the myelination transcriptional program in oligodendrocytes

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1. scibot 08 Sep 2022
  
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  DOI: 10.7554/eLife.77848
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9439679/
Mar 2022
www.embopress.org www.embopress.org

Human cerebral organoids reveal progenitor pathology in EML1-linked cortical malformation

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1. scibot 17 Mar 2022
  
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  DOI: 10.15252/embr.202154027
  
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embopress.org/doi/abs/10.15252/embr.202154027
Feb 2022
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling

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1. scibot 16 Feb 2022
  
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  DOI: 10.1016/j.celrep.2022.110395
  
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pubmed.ncbi.nlm.nih.gov/35172133/
Nov 2021
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The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair

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1. scibot 24 Nov 2021
  
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  DOI: 10.1016/j.devcel.2021.10.022
  
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sciencedirect.com/science/article/pii/S1534580721008534
Aug 2021
52.53.155.43 52.53.155.43

Synthesis and structure-activity relationships of targeted protein degraders for the understudied kinase NEK9

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1. scibot 31 Aug 2021
  
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  DOI: 10.1016/j.crchbi.2021.100008
  
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52.53.155.43/660694af9c8e2ecacd48990031d316948592a872/1-s2.0-S2666246921000082-main-html.html
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

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1. scibot 03 Aug 2021
  
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  RRID:AB_10696895
  
  DOI: 10.1016/j.devcel.2018.11.012
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6286407/
www.jbc.org www.jbc.org

Inhibition of checkpoint kinase 1 following gemcitabine-mediated S phase arrest results in CDC7- and CDK2-dependent replication catastrophe

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1. scibot 01 Aug 2021
  
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  DOI: 10.1074/jbc.RA118.005231
  
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jbc.org/content/294/6/1763.full
Jul 2021
pubs.acs.org pubs.acs.org

Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38

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1. scibot 27 Jul 2021
  
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  DOI: 10.1021/acsptsci.9b00001
  
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pubs.acs.org/doi/full/10.1021/acsptsci.9b00001
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38

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1. scibot 25 Feb 2021
  
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  DOI: 10.1021/acsptsci.9b00001
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7088890/
Jan 2021
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 08 Jan 2021
  
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  DOI: 10.1111/bph.15306
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15306
Sep 2020
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Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma

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1. scibot 13 Sep 2020
  
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  DOI: 10.1016/j.cell.2020.03.062
  
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sciencedirect.com/science/article/pii/S0092867420303950
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Cryo-EM structure of VASH1-SVBP bound to microtubules

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1. scibot 06 Sep 2020
  
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  DOI: 10.7554/eLife.58157
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7449697/
Jan 2020
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Untitled document

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  DOI: 10.1016/j.devcel.2018.11.012
  
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sciencedirect.com/science/article/pii/S1534580718309304
Nov 2017
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Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion

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1. scibot 08 Nov 2017
  
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sciencedirect.com/science/article/pii/S2405471216304100