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    Tuning insulin receptor signaling using de novo-designed agonists
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  3. Jul 2025
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    Parkinson’s disease microglia induce endogenous α-synuclein pathology in patient-specific midbrain organoids
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    biorxiv.org/content/10.1101/2025.07.01.662685v1
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    Cross-species tropism of AAV.CPP.16 in the respiratory tract and its gene therapies against pulmonary fibrosis and viral infection
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    Amplified dosage of the NKX2-1 lineage transcription factor controls its oncogenic role in lung adenocarcinoma
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    The actin and microtubule network regulator WHAMM is identified as a key kidney disease risk gene
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    The human zinc-binding cysteine proteome
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    Granulins rescue inflammation, lysosome dysfunction, lipofuscin, and neuropathology in a mouse model of progranulin deficiency
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    CD14 is a decision-maker between Fas-mediated death and inflammation
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    Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection
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    Crystal structure and biochemical activity of the macrodomain from rubella virus p150
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    Atrial natriuretic peptide signaling co-regulates lipid metabolism and ventricular conduction system gene expression in the embryonic heart
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    SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation
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  30. Oct 2023
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    Parkinson’s-linked LRRK2-G2019S derails AMPAR trafficking, mobility and composition in striatum with cell-type and subunit specificity
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  32. Sep 2023
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    Nectin-3 and shed forms of CSPG4 can serve as epithelial cell receptors for Clostridioides difficile TcdB
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    The Evaluation of Rac1 Signaling as a Potential Therapeutic Target of Alzheimer’s Disease
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    Identification of lysosomal genes associated with prognosis in lung adenocarcinoma
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  37. Jul 2023
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    Super-resolution imaging unveils the self-replication of tau aggregates upon seeding
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  39. Jun 2023
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    METTL14 is decreased and regulates m6A modification of α-synuclein in Parkinson's disease
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  41. Jan 2023
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    Exosome-based bone-targeting drug delivery alleviates impaired osteoblastic bone formation and bone loss in inflammatory bowel diseases
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    Structure and functional mapping of the KRAB-KAP1 repressor complex
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    Chaperone requirements for de novo folding of Saccharomyces cerevisiae septins
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    CRISPR-Cas9 screen in human embryonic stem cells to identify genes required for neural differentiation
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  50. May 2022
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  54. Mar 2022
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    Human cerebral organoids reveal progenitor pathology in EML1-linked cortical malformation
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    Kidney organoids recapitulate human basement membrane assembly in health and disease
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  57. Feb 2022
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  60. Nov 2021
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    The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair
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  62. Aug 2021
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    Synthesis and structure-activity relationships of targeted protein degraders for the understudied kinase NEK9
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    Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation
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    Selective functional inhibition of a tumor-derived p53 mutant by cytosolic chaperones identified using split-YFP in budding yeast
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    Parkinson's Disease-Linked LRRK2-G2019S Mutation Alters Synaptic Plasticity and Promotes Resilience to Chronic Social Stress in Young Adulthood
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    Inhibition of checkpoint kinase 1 following gemcitabine-mediated S phase arrest results in CDC7- and CDK2-dependent replication catastrophe
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  70. Jul 2021
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    Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38
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  72. Feb 2021
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    Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38
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  74. Jan 2021
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  76. Nov 2020
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    Human Condensin I and II Drive Extensive ATP-Dependent Compaction of Nucleosome-Bound DNA
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  79. Sep 2020
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    Cryo-EM structure of VASH1-SVBP bound to microtubules
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    Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication
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    Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation
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  86. Jan 2020
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    An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis
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  91. Nov 2018
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    Amniotic Fluid Exosome Proteomic Profile Exhibits Unique Pathways of Term and Preterm Labor
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  93. Nov 2017
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    Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone
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    Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion
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