51 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Granulins rescue inflammation, lysosome dysfunction, lipofuscin, and neuropathology in a mouse model of progranulin deficiency
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    sciencedirect.com/science/article/pii/S2211124724013366
  3. Sep 2024
  4. www.sciencedirect.com www.sciencedirect.com
    CD14 is a decision-maker between Fas-mediated death and inflammation
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    sciencedirect.com/science/article/pii/S2211124724010362
  5. Aug 2024
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    Non-canonical autophosphorylation of RIPK1 drives timely pyroptosis to control Yersinia infection
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    sciencedirect.com/science/article/pii/S2211124724009914
  7. www.sciencedirect.com www.sciencedirect.com
    Acetate enables metabolic fitness and cognitive performance during sleep disruption
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    sciencedirect.com/science/article/pii/S1550413124002900
  8. Feb 2024
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Crystal structure and biochemical activity of the macrodomain from rubella virus p150
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    ncbi.nlm.nih.gov/pmc/articles/PMC10878246/
  10. Jan 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atrial natriuretic peptide signaling co-regulates lipid metabolism and ventricular conduction system gene expression in the embryonic heart
    1
    1. scibot 20 Jan 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC10792247/
  12. Dec 2023
  13. www.sciencedirect.com www.sciencedirect.com
    SMURF2 predisposes cancer cell toward ferroptosis in GPX4-independent manners by promoting GSTP1 degradation
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    sciencedirect.com/science/article/pii/S1097276523009139
  14. Oct 2023
  15. www.biorxiv.org www.biorxiv.org
    Parkinson’s-linked LRRK2-G2019S derails AMPAR trafficking, mobility and composition in striatum with cell-type and subunit specificity
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    1. scibot 24 Oct 2023
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      DOI: 10.1101/2023.10.13.562231

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    biorxiv.org/content/10.1101/2023.10.13.562231v1
  16. Sep 2023
  17. journals.asm.org journals.asm.org
    Nectin-3 and shed forms of CSPG4 can serve as epithelial cell receptors for Clostridioides difficile TcdB
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1128/mbio.01857-23

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    journals.asm.org/doi/10.1128/mbio.01857-23
  18. Aug 2023
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Evaluation of Rac1 Signaling as a Potential Therapeutic Target of Alzheimer’s Disease
    1
    1. scibot 16 Aug 2023
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      DOI: 10.3390/ijms241511880

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    ncbi.nlm.nih.gov/pmc/articles/PMC10418761/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of lysosomal genes associated with prognosis in lung adenocarcinoma
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    1. scibot 12 Aug 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10413022/
  21. Jul 2023
  22. www.sciencedirect.com www.sciencedirect.com
    Super-resolution imaging unveils the self-replication of tau aggregates upon seeding
    1
    1. scibot 05 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112725

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    sciencedirect.com/science/article/pii/S2211124723007362
  23. Jun 2023
  24. onlinelibrary.wiley.com onlinelibrary.wiley.com
    METTL14 is decreased and regulates m6A modification of α-synuclein in Parkinson's disease
    1
    1. scibot 15 Jun 2023
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      DOI: 10.1111/jnc.15882

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15882
  25. Jan 2023
  26. www.sciencedirect.com www.sciencedirect.com
    Exosome-based bone-targeting drug delivery alleviates impaired osteoblastic bone formation and bone loss in inflammatory bowel diseases
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    1. scibot 06 Jan 2023
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      DOI: 10.1016/j.xcrm.2022.100881

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    sciencedirect.com/science/article/pii/S2666379122004451
  27. Dec 2022
  28. www.embopress.org www.embopress.org
    Structure and functional mapping of the KRAB-KAP1 repressor complex
    1
    1. scibot 27 Dec 2022
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      DOI: 10.15252/embj.2022111179

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    embopress.org/doi/10.15252/embj.2022111179
  29. link.springer.com link.springer.com
    AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer
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      DOI: 10.1007/s00018-022-04638-y

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    link.springer.com/article/10.1007/s00018-022-04638-y
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chaperone requirements for de novo folding of Saccharomyces cerevisiae septins
    1
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      DOI: 10.1091/mbc.E22-07-0262

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    ncbi.nlm.nih.gov/pmc/articles/PMC9635297/
  31. Sep 2022
  32. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Cas9 screen in human embryonic stem cells to identify genes required for neural differentiation
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    1. scibot 18 Sep 2022
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      DOI: 10.1016/j.xpro.2022.101682

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    sciencedirect.com/science/article/pii/S2666166722005627
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAG2 promotes the myelination transcriptional program in oligodendrocytes
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    1. scibot 08 Sep 2022
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      DOI: 10.7554/eLife.77848

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    ncbi.nlm.nih.gov/pmc/articles/PMC9439679/
  34. May 2022
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A bioactive phlebovirus-like envelope protein in a hookworm endogenous virus
    1
    1. scibot 28 May 2022
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      DOI: 10.1126/sciadv.abj6894

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    ncbi.nlm.nih.gov/pmc/articles/PMC9094657/
  36. Apr 2022
  37. aacrjournals.org aacrjournals.org
    Development of novel aptamer-based targeted chemotherapy for bladder cancer
    1
    1. scibot 05 Apr 2022
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      DOI: 10.1158/0008-5472.CAN-21-2691

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    aacrjournals.org/cancerres/article/82/6/1128/682057/Development-of-Novel-Aptamer-Based-Targeted
  38. Mar 2022
  39. www.embopress.org www.embopress.org
    Human cerebral organoids reveal progenitor pathology in EML1-linked cortical malformation
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    1. scibot 17 Mar 2022
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      DOI: 10.15252/embr.202154027

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    embopress.org/doi/abs/10.15252/embr.202154027
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kidney organoids recapitulate human basement membrane assembly in health and disease
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      DOI: 10.7554/eLife.73486

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    ncbi.nlm.nih.gov/pmc/articles/PMC8849328/
  41. Feb 2022
  42. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TP53 promotes lineage commitment of human embryonic stem cells through ciliogenesis and sonic hedgehog signaling
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      DOI: 10.1016/j.celrep.2022.110395

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    pubmed.ncbi.nlm.nih.gov/35172133/
  43. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.15745

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15745
  44. Nov 2021
  45. www.sciencedirect.com www.sciencedirect.com
    The ESCRT machinery counteracts Nesprin-2G-mediated mechanical forces during nuclear envelope repair
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    1. scibot 24 Nov 2021
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      DOI: 10.1016/j.devcel.2021.10.022

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    sciencedirect.com/science/article/pii/S1534580721008534
  46. Aug 2021
  47. 52.53.155.43 52.53.155.43
    Synthesis and structure-activity relationships of targeted protein degraders for the understudied kinase NEK9
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    1. scibot 31 Aug 2021
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      DOI: 10.1016/j.crchbi.2021.100008

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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neutrophils require SKAP2 for reactive oxygen species production following C-type lectin and Candida stimulation
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      DOI: 10.1016/j.isci.2021.102871

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    ncbi.nlm.nih.gov/pmc/articles/PMC8346660/
  49. academic.oup.com academic.oup.com
    Selective functional inhibition of a tumor-derived p53 mutant by cytosolic chaperones identified using split-YFP in budding yeast
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      DOI: 10.1093/g3journal/jkab230

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    academic.oup.com/g3journal/advance-article/doi/10.1093/g3journal/jkab230/6318398
  50. www.jneurosci.org www.jneurosci.org
    Untitled document
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      DOI: 10.1523/JNEUROSCI.1457-18.2018

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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.devcel.2018.11.012

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    ncbi.nlm.nih.gov/pmc/articles/PMC6286407/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Parkinson's Disease-Linked LRRK2-G2019S Mutation Alters Synaptic Plasticity and Promotes Resilience to Chronic Social Stress in Young Adulthood
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      DOI: 10.1523/JNEUROSCI.1457-18.2018

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    ncbi.nlm.nih.gov/pmc/articles/PMC6222060/
  53. www.jbc.org www.jbc.org
    Inhibition of checkpoint kinase 1 following gemcitabine-mediated S phase arrest results in CDC7- and CDK2-dependent replication catastrophe
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      DOI: 10.1074/jbc.RA118.005231

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    jbc.org/content/294/6/1763.full
  54. Jul 2021
  55. pubs.acs.org pubs.acs.org
    Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38
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      DOI: 10.1021/acsptsci.9b00001

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    pubs.acs.org/doi/full/10.1021/acsptsci.9b00001
  56. Feb 2021
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Sensitivity to CDK2 Inhibition Discriminates the Molecular Mechanisms of CHK1 Inhibitors as Monotherapy or in Combination with the Topoisomerase I Inhibitor SN38
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    ncbi.nlm.nih.gov/pmc/articles/PMC7088890/
  58. Jan 2021
  59. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.15306

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15306
  60. Nov 2020
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Condensin I and II Drive Extensive ATP-Dependent Compaction of Nucleosome-Bound DNA
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      DOI: 10.1016/j.molcel.2020.04.026

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    ncbi.nlm.nih.gov/pmc/articles/PMC7335352/
  62. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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      DOI: 10.1002/1878-0261.12835

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  63. Sep 2020
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryo-EM structure of VASH1-SVBP bound to microtubules
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      DOI: 10.7554/eLife.58157

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  65. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication
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    Constitutive Interferon Attenuates RIPK1/3-Mediated Cytokine Translation
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      DOI: 10.1016/j.celrep.2019.12.073

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    Endocrine-Exocrine Signaling Drives Obesity-Associated Pancreatic Ductal Adenocarcinoma
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      DOI: 10.1016/j.cell.2020.03.062

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  68. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      DOI: 10.1111/bph.14935

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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst
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      DOI: 10.7554/eLife.56656

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  70. Jan 2020
  71. onlinelibrary.wiley.com onlinelibrary.wiley.com
    High‐potassium preconditioning enhances tolerance to focal cerebral ischemia‐reperfusion injury through anti‐apoptotic effects in male rats
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    Local Fatty Acid Channeling into Phospholipid Synthesis Drives Phagophore Expansion during Autophagy
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    An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis
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      DOI: 10.1016/j.molcel.2019.10.016

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      DOI: 10.1016/j.devcel.2018.11.012

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  75. Nov 2018
  76. academic.oup.com academic.oup.com
    Amniotic Fluid Exosome Proteomic Profile Exhibits Unique Pathways of Term and Preterm Labor
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  77. Nov 2017
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    Renal Sodium Gradient Orchestrates a Dynamic Antibacterial Defense Zone
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    Multiparametric Analysis of Cell Shape Demonstrates that β-PIX Directly Couples YAP Activation to Extracellular Matrix Adhesion
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