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Cancer-Associated Fibroblasts Promote Epithelial-Mesenchymal Transition and Classical to Basal Subtype Shift in Pancreatic Cancer

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1. scibot 13 Jun 2026
  
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  DOI: 10.1158/0008-5472.CAN-25-0331
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13245478/
May 2026
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ALDH1A3 promotes the lung metastatic organotropism of pancreatic ductal adenocarcinoma through semaphorin signaling

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1. scibot 22 May 2026
  
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  DOI: 10.1016/j.isci.2026.115950
  
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sciencedirect.com/science/article/pii/S2589004226013258
Apr 2026
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ssrn-6480291-html.html

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1. scibot 09 Apr 2026
  
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  DOI: 10.2139/ssrn.6480291
  
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54.241.53.176/c461ed449e47879eb34700a4a7bf615b15d9690c/ssrn-6480291-html.html
Mar 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Dual pancreatic carcinomas: clonally related or independent primaries?

1
1. scibot 21 Mar 2026
  
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  DOI: 10.1038/s41698-026-01313-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12996456/
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Modeling human prenatal adrenocortical functional zonation dynamics from pluripotent stem cells

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1. scibot 06 Mar 2026
  
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  DOI: 10.1016/j.stem.2026.02.002
  
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sciencedirect.com/science/article/pii/S193459092600072X
Feb 2026
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Generation and characterization of SOX17-specific EGFP expressing human induced pluripotent stem cell line, KSCBi017-A-4, using CRISPR/Cas9

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1. scibot 24 Feb 2026
  
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  DOI: 10.1016/j.scr.2026.103943
  
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sciencedirect.com/science/article/pii/S1873506126000395
Nov 2025
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Stage-sensitive potential of isolated rabbit ICM to differentiate into extraembryonic lineages

1
1. scibot 20 Nov 2025
  
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  DOI: 10.1093/biolre/ioaf157
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12621310/
Sep 2025
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Signaling reprogramming via Stat3 activation unravels high-fidelity human post-implantation embryo modeling

1
1. scibot 17 Sep 2025
  
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  DOI: 10.1016/j.stem.2025.08.011
  
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sciencedirect.com/science/article/pii/S1934590925003030
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Combinatorial BMP4 and activin direct the choice between alternate routes to endoderm in a stem cell model of human gastrulation

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1. scibot 11 Sep 2025
  
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  DOI: 10.1016/j.devcel.2025.08.009
  
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sciencedirect.com/science/article/pii/S1534580725005295
Aug 2025
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HMGA2 Expression Predicts Subtype, Survival, and Treatment Outcome in Pancreatic Ductal Adenocarcinoma

1
1. scibot 19 Aug 2025
  
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  DOI: 10.1158/1078-0432.CCR-24-2200
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11967372/
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Generation of induced pluripotent stem cell lines from three LGMD R1 patients carrying CAPN3 hypomorphic intronic variant c.1746-20C > G

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1. scibot 19 Aug 2025
  
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  DOI: 10.1016/j.scr.2025.103803
  
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sciencedirect.com/science/article/pii/S1873506125001539
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Transgene-free generation of mouse post-gastrulation whole embryo models solely from naive ESCs and iPSCs

1
1. scibot 08 Aug 2025
  
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  DOI: 10.1016/j.stem.2025.07.005
  
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sciencedirect.com/science/article/pii/S1934590925002620
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A complete model of mouse embryogenesis through organogenesis enabled by chemically induced embryo founder cells

1
1. scibot 08 Aug 2025
  
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  RRID:AB_10705521
  
  DOI: 10.1016/j.cell.2025.07.018
  
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sciencedirect.com/science/article/pii/S0092867425008074
Jun 2025
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Protocol for differentiation of human pluripotent stem cells into definitive endoderm lineage in a chemically defined and growth factor-free system

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1. scibot 17 Jun 2025
  
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  RRID:AB_10705521
  
  DOI: 10.1016/j.xpro.2025.103889
  
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sciencedirect.com/science/article/pii/S2666166725002953
May 2025
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Post-gastrulation amnioids as a stem cell-derived model of human extra-embryonic development

1
1. scibot 17 May 2025
  
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  RRID:AB_10705521
  
  DOI: 10.1016/j.cell.2025.04.025
  
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sciencedirect.com/science/article/pii/S0092867425004581
Mar 2025
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Self-organization of mouse embryonic stem cells into reproducible pre-gastrulation embryo models via CRISPRa programming

1
1. scibot 23 Mar 2025
  
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  RRID:AB_10705521
  
  DOI: 10.1016/j.stem.2025.02.015
  
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cell.com/cell-stem-cell/fulltext/S1934-5909(25)00083-9
Jan 2025
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Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation

1
1. scibot 23 Jan 2025
  
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  DOI: 10.1016/j.cell.2024.12.009
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12160003/
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Modeling early gastrulation in human blastoids with DNA methylation patterns of natural blastocysts

1
1. scibot 16 Jan 2025
  
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  DOI: 10.1016/j.stem.2024.12.010
  
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sciencedirect.com/science/article/pii/S1934590924004508
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A spatiotemporal and machine-learning platform facilitates the manufacturing of hPSC-derived esophageal mucosa

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1. scibot 16 Jan 2025
  
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  DOI: 10.1016/j.devcel.2024.12.030
  
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sciencedirect.com/science/article/pii/S153458072400769X
Nov 2024
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Control of Murine Brown Adipocyte Development by GATA6

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1. scibot 16 Nov 2024
  
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  DOI: 10.1016/j.devcel.2023.08.003
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10842351/
Sep 2024
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In utero morphological and functional properties of bovine trophoblastic vesicles

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1. scibot 27 Sep 2024
  
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  RRID:AB_10705521
  
  DOI: 10.1002/mrd.23767
  
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onlinelibrary.wiley.com/doi/10.1002/mrd.23767
May 2024
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Transcription factor dynamics, oscillation, and functions in human enteroendocrine cell differentiation

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1. scibot 14 May 2024
  
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  DOI: 10.1016/j.stem.2024.04.015
  
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sciencedirect.com/science/article/pii/S1934590924001425
Apr 2024
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Generation and characterization of GATA6-specific EGFP expressing human induced pluripotent stem cell line, KSCBi017-A-1, using CRISPR/Cas9

2
1. scibot 30 Apr 2024
  
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  DOI: 10.1016/j.scr.2024.103426
  
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2. scibot 30 Apr 2024
  
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  DOI: 10.1016/j.scr.2024.103426
  
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sciencedirect.com/science/article/pii/S1873506124001247
Feb 2024
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Hypoxia at 3D organoid establishment selects essential subclones within heterogenous pancreatic cancer

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1. scibot 23 Feb 2024
  
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  DOI: 10.3389/fcell.2024.1327772
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10875002/
Jan 2024
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A pancreatic cancer organoid platform identifies an inhibitor specific to mutant KRAS

2
1. scibot 11 Jan 2024
  
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  RRID:AB_10705521
  
  DOI: 10.1016/j.stem.2023.11.011
  
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2. scibot 11 Jan 2024
  
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  DOI: 10.1016/j.stem.2023.11.011
  
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sciencedirect.com/science/article/pii/S1934590923004113
Dec 2023
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A pancreatic cancer organoid platform identifies an inhibitor specific to mutant KRAS

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1. scibot 29 Dec 2023
  
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  DOI: 10.1016/j.stem.2023.11.011
  
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sciencedirect.com/science/article/pii/S1934590923004113
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Dissecting embryonic and extraembryonic lineage crosstalk with stem cell co-culture

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1. scibot 20 Dec 2023
  
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  DOI: 10.1016/j.cell.2023.11.008
  
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sciencedirect.com/science/article/pii/S0092867423012254
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Generation of the Human iPSC line from spontaneous Late-Onset Alzheimer’s disease patient with ApoE3/3 genotype and Sex-, Age-, and ApoE-Matched healthy control

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1. scibot 14 Dec 2023
  
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  DOI: 10.1016/j.scr.2023.103273
  
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sciencedirect.com/science/article/pii/S1873506123002593
Oct 2023
52.53.155.43 52.53.155.43

Transgene directed induction of a stem cell-derived human embryo model

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1. scibot 13 Oct 2023
  
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  DOI: 10.1101/2023.06.15.545082
  
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52.53.155.43/5a401c55d861c2dcc062c9d148face33c192a62e/2023.06.15.545082v1.full-html.html
Aug 2023
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Reconstructing human brown fat developmental trajectory in vitro

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1. scibot 30 Aug 2023
  
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  RRID:AB_10705521
  
  DOI: 10.1016/j.devcel.2023.08.001
  
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sciencedirect.com/science/article/abs/pii/S1534580723003970
May 2023
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Multimodal characterization of murine gastruloid development

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1. scibot 20 May 2023
  
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  DOI: 10.1016/j.stem.2023.04.018
  
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sciencedirect.com/science/article/pii/S1934590923001704
Apr 2023
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Cynomolgus monkey embryo model captures gastrulation and early pregnancy

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1. scibot 07 Apr 2023
  
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  DOI: 10.1016/j.stem.2023.03.009
  
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sciencedirect.com/science/article/pii/S1934590923000802
Jan 2023
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Decoding anterior-posterior axis emergence among mouse, monkey, and human embryos

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1. scibot 11 Jan 2023
  
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  DOI: 10.1016/j.devcel.2022.12.004
  
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sciencedirect.com/science/article/pii/S1534580722008486
Dec 2022
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Organoid modeling of human fetal lung alveolar development reveals mechanisms of cell fate patterning and neonatal respiratory disease

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1. scibot 11 Dec 2022
  
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  RRID:AB_10705521
  
  DOI: 10.1016/j.stem.2022.11.013
  
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Aug 2022
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Spatial molecular anatomy of germ layers in the gastrulating cynomolgus monkey embryo

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  DOI: 10.1016/j.celrep.2022.111285
  
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CRISPR engineered mouse embryonic stem cells with Sox2-tdTomato and Gata6-GFP knock-in for endoderm differentiation

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Embigin is a fibronectin receptor that affects sebaceous gland differentiation and metabolism

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In vitro attachment and symmetry breaking of a human embryo model assembled from primed embryonic stem cells

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Chromatin remodeling is restricted by transient GATA6 binding during iPSC differentiation to definitive endoderm

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  DOI: 10.1016/j.isci.2022.104300
  
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Identification of treatment-induced vulnerabilities in pancreatic cancer patients using functional model systems

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  DOI: 10.15252/emmm.202114876
  
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Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer

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Differentiation of human pluripotent stem cells into pancreatic duct-like organoids

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Nov 2021
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MK2 promotes Tfcp2l1 degradation via β-TrCP ubiquitin ligase to regulate mouse embryonic stem cell self-renewal

1
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May 2021
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The transcription factor Rreb1 regulates epithelial architecture, invasiveness, and vasculogenesis in early mouse embryos

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  DOI: 10.7554/eLife.64811
  
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GATA6 defines endoderm fate by controlling chromatin accessibility during differentiation of human-induced pluripotent stem cells

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Apr 2021
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Chimeric contribution of human extended pluripotent stem cells to monkey embryos ex vivo

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Dec 2020
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High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures

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  DOI: 10.7554/eLife.59445
  
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Cdk1 Controls Global Epigenetic Landscape in Embryonic Stem Cells

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Jan 2020
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Generation of Blastocyst-like Structures from Mouse Embryonic and Adult Cell Cultures

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  DOI: 10.1016/j.cell.2019.09.029
  
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FOXA2 Is Required for Enhancer Priming during Pancreatic Differentiation

1
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Gata6+ Pericardial Cavity Macrophages Relocate to the Injured Heart and Prevent Cardiac Fibrosis

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  DOI: 10.1016/j.immuni.2019.06.010
  
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Untitled document

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Untitled document

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  DOI: 10.1016/j.scr.2018.101382
  
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Nov 2018
europepmc.org europepmc.org

Untitled document

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Micropattern differentiation of mouse pluripotent stem cells recapitulates embryo regionalized cell fate patterning

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Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression

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Nov 2017
europepmc.org europepmc.org

A tissue-specific, Gata6-driven transcriptional program instructs remodeling of the mature arterial tree.

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DUSP9 Modulates DNA Hypomethylation in Female Mouse Pluripotent Stem Cells

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Genome Editing in hPSCs Reveals GATA6 Haploinsufficiency and a Genetic Interaction with GATA4 in Human Pancreatic Development

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