38 Matching Annotations
  1. Last 7 days
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    C1QBP-STAT1 interaction promotes activation of the c-Myc-CHK1/CHK2 signalling axis and radioresistance in lung cancer
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    aacrjournals.org/mcr/article/24/5/315/784167/C1QBP-STAT1-Interaction-Promotes-Activation-of-the
  3. Apr 2026
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    p16 expression confers sensitivity to CDK2 inhibitors in cyclin E1–driven ovarian cancers
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    pmc.ncbi.nlm.nih.gov/articles/PMC13089646/
  5. Jan 2026
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    CTCF/cohesin-binding sites are susceptible to replication-associated DNA damage and genomic instability in cancer cells
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    sciencedirect.com/science/article/pii/S2589004226000210
  7. Dec 2025
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    PatientProfiler: building patient-specific signaling models from proteogenomic data
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    pmc.ncbi.nlm.nih.gov/articles/PMC12672659/
  9. Oct 2025
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    Identification of molecular markers and exploration of the oncogenic role of exomeres in hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S2211124725012318
  11. Mar 2025
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    p53 enhances DNA repair and suppresses cytoplasmic chromatin fragments and inflammation in senescent cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11882782/
  13. Nov 2024
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    Profound synthetic lethality between SMARCAL1 and FANCM
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    sciencedirect.com/science/article/pii/S1097276524008566
  15. Aug 2024
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    Histone chaperone HIRA, promyelocytic leukemia protein, and p62/SQSTM1 coordinate to regulate inflammation during cell senescence
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  17. Jul 2024
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    Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton
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    sciencedirect.com/science/article/pii/S2211124724008398
  19. May 2024
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    Molecular subtypes of neuroendocrine carcinomas: A cross-tissue classification framework based on five transcriptional regulators
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    sciencedirect.com/science/article/pii/S1535610824001636
  21. Apr 2024
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    BLM helicase unwinds lagging strand substrates to assemble the ALT telomere damage response
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  23. Mar 2024
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    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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    Targeting up-regulated cIAP2 in SOX10-deficient drug tolerant melanoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10527992/
  26. Feb 2024
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    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
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    sciencedirect.com/science/article/pii/S2211124724001736
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    RNF4 prevents genomic instability caused by chronic DNA under-replication
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    sciencedirect.com/science/article/pii/S1568786424000223
  29. Dec 2023
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    FANCD2-dependent mitotic DNA synthesis relies on PCNA K164 ubiquitination
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  31. Oct 2023
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    DNA damage induces nuclear envelope rupture through ATR-mediated phosphorylation of lamin A/C
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  33. Aug 2023
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    mct-23-0025 (1)-html.html
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    C1orf112 teams up with FIGNL1 to facilitate RAD51 filament disassembly and DNA interstrand cross-link repair
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    sciencedirect.com/science/article/pii/S221112472300918X
  36. Jun 2023
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    CDT1 inhibits CMG helicase in early S phase to separate origin licensing from DNA synthesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC7614657/
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    Rapid adaptation to CDK2 inhibition exposes intrinsic cell-cycle plasticity
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    sciencedirect.com/science/article/pii/S0092867423005329
  39. Apr 2023
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    ERCC6L2 mitigates replication stress and promotes centromere stability
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  41. Feb 2023
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    RIF1 suppresses the formation of single-stranded ultrafine anaphase bridges via protein phosphatase 1
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  43. Jan 2023
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    The human placenta shapes the phenotype of decidual macrophages
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    sciencedirect.com/science/article/pii/S2211124722018812
  45. Sep 2022
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    A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice
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    nature.com/articles/s42003-022-03917-5
  47. May 2022
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    A PARylation-phosphorylation cascade promotes TOPBP1 loading and RPA-RAD51 exchange in homologous recombination
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  49. Mar 2022
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    CDK/cyclin dependencies define extreme cancer cell-cycle heterogeneity and collateral vulnerabilities
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  51. Nov 2021
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    Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulation
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    cell.com/cancer-cell/fulltext/S1535-6108(21)00559-6
  53. Sep 2021
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    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
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    sciencedirect.com/science/article/pii/S1097276521006833
  55. Aug 2021
  56. academic.oup.com academic.oup.com
    Oestrogen signalling drives ciliogenesis in human endometrial organoids
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    academic.oup.com/endo/article/160/10/2282/5530205
  57. Apr 2021
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    Functional interrogation of DNA damage response variants with base editing screens
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    sciencedirect.com/science/article/pii/S0092867421000842
  59. Sep 2020
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    Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase
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  61. Jan 2020
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    C1QBP Promotes Homologous Recombination by Stabilizing MRE11 and Controlling the Assembly and Activation of MRE11/RAD50/NBS1 Complex
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    sciencedirect.com/science/article/pii/S1097276519304794
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    Phosphorylation-mediated interactions with TOPBP1 couple 53BP1 and 9-1-1 to control the G1 DNA damage checkpoint
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    ncbi.nlm.nih.gov/pmc/articles/PMC6561707/
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    Fork Cleavage-Religation Cycle and Active Transcription Mediate Replication Restart after Fork Stalling at Co-transcriptional R-Loops
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  65. Nov 2017
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    RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis
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