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Aug 2026
www.sciencedirect.com www.sciencedirect.com

Chemical tools for inhibition and activity-based profiling of glucocerebrosidase in vitro and in vivo

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1. scibot 11 Aug 2026
  
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  RRID:AB_1078958
  
  DOI: 10.1016/j.chembiol.2026.07.007
  
  Resource: (Sigma-Aldrich Cat# G4171, RRID:AB_1078958)
  
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sciencedirect.com/science/article/pii/S2451945626002801
May 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

An altered cell-specific subcellular distribution of translesion synthesis DNA polymerase kappa (POLK) in aging mouse neurons

1
1. scibot 20 May 2026
  
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  RRID:AB_1078958
  
  DOI: 10.7554/eLife.101533
  
  Resource: (Sigma-Aldrich Cat# G4171, RRID:AB_1078958)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC13171111/
Jan 2026
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

A guide to selecting high-performing antibodies for GCase (UniProt ID: P04062) for use in western blot, immunoprecipitation, and immunofluorescence

1
1. scibot 23 Jan 2026
  
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  AB_1078958
  
  DOI: 10.12688/f1000research.174230.1
  
  Resource: (Sigma-Aldrich Cat# G4171, RRID:AB_1078958)
  
  Curator: @scibot
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12800601/
Dec 2024
link.springer.com link.springer.com

African ancestry neurodegeneration risk variant disrupts an intronic branchpoint in GBA1

1
1. scibot 17 Dec 2024
  
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  RRID:AB_1078958
  
  DOI: 10.1038/s41594-024-01423-2
  
  Resource: (Sigma-Aldrich Cat# G4171, RRID:AB_1078958)
  
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link.springer.com/article/10.1038/s41594-024-01423-2
Jul 2024
www.biorxiv.org www.biorxiv.org

Loss of the lysosomal lipid flippase ATP10B leads to progressive dopaminergic neurodegeneration and Parkinsonian motor deficits

1
1. scibot 23 Jul 2024
  
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  RRID:AB_1078958
  
  DOI: 10.1101/2024.07.09.602700
  
  Resource: (Sigma-Aldrich Cat# G4171, RRID:AB_1078958)
  
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biorxiv.org/content/10.1101/2024.07.09.602700v1
Dec 2023
www.sciencedirect.com www.sciencedirect.com

Molecular determinants of the crosstalk between endosomal microautophagy and chaperone-mediated autophagy

1
1. scibot 07 Dec 2023
  
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  RRID:AB_1078958
  
  DOI: 10.1016/j.celrep.2023.113529
  
  Resource: (Sigma-Aldrich Cat# G4171, RRID:AB_1078958)
  
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sciencedirect.com/science/article/pii/S2211124723015413
Jan 2023
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Neuronopathic GBA1L444P mutation accelerates Glucosylsphingosine levels and formation of hippocampal alpha-synuclein inclusions

1
1. scibot 19 Jan 2023
  
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  RRID:AB_1078958
  
  DOI: 10.1523/JNEUROSCI.0680-22.2022
  
  Resource: (Sigma-Aldrich Cat# G4171, RRID:AB_1078958)
  
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pmc.ncbi.nlm.nih.gov/articles/PMC9864632/
Jul 2022
www.nature.com www.nature.com

LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson’s disease

1
1. scibot 27 Jul 2022
  
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  RRID:AB_1078958
  
  DOI: 10.1038/s41531-022-00354-3
  
  Resource: (Sigma-Aldrich Cat# G4171, RRID:AB_1078958)
  
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nature.com/articles/s41531-022-00354-3
Nov 2021
www.sciencedirect.com www.sciencedirect.com

Rescue of α-synuclein aggregation in Parkinson’s patient neurons by synergistic enhancement of ER proteostasis and protein trafficking

1
1. scibot 18 Nov 2021
  
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  RRID:AB_1078958
  
  DOI: 10.1016/j.neuron.2021.10.032
  
  Resource: (Sigma-Aldrich Cat# G4171, RRID:AB_1078958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1078958
  
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sciencedirect.com/science/article/pii/S089662732100862X
Oct 2021
www.sciencedirect.com www.sciencedirect.com

TRIP12 ubiquitination of glucocerebrosidase contributes to neurodegeneration in Parkinson’s disease

1
1. scibot 13 Oct 2021
  
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  RRID:AB_1078958
  
  DOI: 10.1016/j.neuron.2021.09.031
  
  Resource: (Sigma-Aldrich Cat# G4171, RRID:AB_1078958)
  
  Curator: @scibot
  
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sciencedirect.com/science/article/pii/S0896627321007042
Aug 2021
www.sciencedirect.com www.sciencedirect.com

Rescue of a lysosomal storage disorder caused by Grn loss of function with a brain penetrant progranulin biologic

1
1. scibot 27 Aug 2021
  
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  RRID:AB_1078958
  
  DOI: 10.1016/j.cell.2021.08.002
  
  Resource: (Sigma-Aldrich Cat# G4171, RRID:AB_1078958)
  
  Curator: @scibot
  
  SciCrunch record: RRID:AB_1078958
  
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sciencedirect.com/science/article/pii/S0092867421009442
Apr 2021
www.sciencedirect.com www.sciencedirect.com

Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C

1
1. scibot 20 Apr 2021
  
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  RRID:AB_1078958
  
  DOI: 10.1016/j.devcel.2021.03.032
  
  Resource: (Sigma-Aldrich Cat# G4171, RRID:AB_1078958)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_1078958
  
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  RRIDCUR:Validated RRID:AB_1078958
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RRIDCUR:Validated

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sciencedirect.com/science/article/pii/S1534580721003075
Jan 2020
www.sciencedirect.com www.sciencedirect.com

Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult

1
1. scibot 13 Jan 2020
  
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  RRID:AB_1078958
  
  DOI: 10.1016/j.neuron.2019.12.004
  
  Resource: (Sigma-Aldrich Cat# G4171, RRID:AB_1078958)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_1078958
  
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  RRID:AB_1078958 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0896627319310463
Nov 2018
www.jneurosci.org www.jneurosci.org

Glucosylsphingosine promotes α-synuclein pathology in mutant GBA-associated Parkinson's disease

1
1. scibot 05 Nov 2018
  
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  RRID:AB_1078958
  
  Curator: @anp055
  
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  (Sigma-Aldrich Cat# G4171, RRID:AB_1078958)
  
  SciCrunch record: RRID:AB_1078958
  
  Alternate resolvers: SciCrunch xml N2T identifiers.org
  
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  RRID:AB_1078958 RRIDCUR:Validated
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jneurosci.org/content/37/40/9617