61 Matching Annotations
  1. Dec 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening
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    1. scibot 10 Dec 2024
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      DOI: 10.1016/j.cels.2024.11.004

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    sciencedirect.com/science/article/pii/S2405471224003375
  3. Nov 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of cathepsin L ameliorates inflammation through the A20/NF-κB pathway in endotoxin-induced acute lung injury
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    1. scibot 26 Nov 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC11570319/
  5. Aug 2024
  6. www.sciencedirect.com www.sciencedirect.com
    Defective endomembrane dynamics in Rab27a deficiency impairs nucleic acid sensing and cytokine secretion in immune cells
    1
    1. scibot 21 Aug 2024
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    sciencedirect.com/science/article/pii/S2211124724009379
  7. Jul 2024
  8. www.sciencedirect.com www.sciencedirect.com
    TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration
    1
    1. scibot 15 Jul 2024
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    sciencedirect.com/science/article/pii/S2211124721002096
  9. Jun 2024
  10. link.springer.com link.springer.com
    DL-3-n-Butylphthalide Ameliorates Post-stroke Emotional Disorders by Suppressing Neuroinflammation and PANoptosis
    1
    1. scibot 06 Jun 2024
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      DOI: 10.1007/s11064-024-04171-3

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    link.springer.com/article/10.1007/s11064-024-04171-3
  11. May 2024
  12. www.sciencedirect.com www.sciencedirect.com
    A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1
    1
    1. scibot 08 May 2024
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    sciencedirect.com/science/article/pii/S1550413124001359
  13. Apr 2024
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening
    1
    1. scibot 28 Apr 2024
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      DOI: 10.1101/2024.04.07.588166

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    ncbi.nlm.nih.gov/pmc/articles/PMC11030420/
  15. Mar 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Adipose stem cells control obesity-induced T cell infiltration into adipose tissue
    1
    1. scibot 19 Mar 2024
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    sciencedirect.com/science/article/pii/S2211124724002912
  17. Feb 2024
  18. www.sciencedirect.com www.sciencedirect.com
    Alternative mRNA splicing events and regulators in epidermal differentiation
    2
    1. scibot 27 Feb 2024
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    2. scibot 27 Feb 2024
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      DOI: 10.1016/j.celrep.2024.113814

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    sciencedirect.com/science/article/pii/S2211124724001426
  19. Jan 2024
  20. www.science.org www.science.org
    Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines
    1
    1. scibot 18 Jan 2024
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    science.org/doi/10.1126/sciadv.ade1282
  21. Oct 2023
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Endocrine Therapy Synergizes with SMAC Mimetics to Potentiate Antigen Presentation and Tumor Regression in Hormone Receptor–Positive Breast Cancer
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1158/0008-5472.CAN-23-1711

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    ncbi.nlm.nih.gov/pmc/articles/PMC10543960/
  23. Jul 2023
  24. www.sciencedirect.com www.sciencedirect.com
    Targeting endometrial inflammation in intrauterine adhesion ameliorates endometrial fibrosis by priming MSCs to secrete C1INH
    1
    1. scibot 07 Jul 2023
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      DOI: 10.1016/j.isci.2023.107201

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    sciencedirect.com/science/article/pii/S2589004223012786
  25. Jun 2023
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipopolysaccharide increases bitter taste sensitivity via epigenetic changes in Tas2r gene clusters
    1
    1. scibot 08 Jun 2023
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      DOI: 10.1016/j.isci.2023.106920

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    ncbi.nlm.nih.gov/pmc/articles/PMC10239704/
  27. www.sciencedirect.com www.sciencedirect.com
    The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-κB
    1
    1. scibot 03 Jun 2023
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      DOI: 10.1016/j.celrep.2023.112586

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    sciencedirect.com/science/article/pii/S2211124723005971
  28. www.sciencedirect.com www.sciencedirect.com
    Secreted ORF8 induces monocytic pro-inflammatory cytokines through NLRP3 pathways in severe patients with COVID-19
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    1. scibot 02 Jun 2023
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      DOI: 10.1016/j.isci.2023.106929

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    sciencedirect.com/science/article/pii/S2589004223010064
  29. www.sciencedirect.com www.sciencedirect.com
    Cancer cell-autonomous cGAS-STING response confers drug resistance
    1
    1. scibot 01 Jun 2023
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      DOI: 10.1016/j.chembiol.2023.05.005

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    sciencedirect.com/science/article/pii/S2451945623001411
  30. May 2023
  31. www.mdpi.com www.mdpi.com
    Comparative Analysis of Six IRF Family Members in Alveolar Epithelial Cell-Intrinsic Antiviral Responses
    1
    1. scibot 06 May 2023
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      DOI: 10.3390/cells10102600

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    mdpi.com/2073-4409/10/10/2600/htm
  32. Apr 2023
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines
    1
    1. scibot 27 Apr 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10115456/
  34. Mar 2023
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FDA-approved Abl/EGFR/PDGFR kinase inhibitors show potent efficacy against pandemic and seasonal influenza A virus infections of human lung explants
    1
    1. scibot 26 Mar 2023
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      DOI: 10.1016/j.isci.2023.106309

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    ncbi.nlm.nih.gov/pmc/articles/PMC10034449/
  36. Feb 2023
  37. www.sciencedirect.com www.sciencedirect.com
    IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interactionwith the AITL microenvironment
    1
    1. scibot 03 Feb 2023
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      DOI: 10.1016/j.ccell.2023.01.003

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    sciencedirect.com/science/article/pii/S153561082300003X
  38. Jan 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice
    1
    1. scibot 06 Jan 2023
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      DOI: 10.1016/j.isci.2022.105769

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    ncbi.nlm.nih.gov/pmc/articles/PMC9804112/
  40. Nov 2022
  41. www.science.org www.science.org
    An orally active, small-molecule TNF inhibitor that disrupts the homotrimerization interface improves inflammatory arthritis in mice
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    1. scibot 12 Nov 2022
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      DOI: 10.1126/scisignal.abi8713

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    science.org/doi/10.1126/scisignal.abi8713
  42. Oct 2022
  43. www.sciencedirect.com www.sciencedirect.com
    Competition for endothelial cell polarity drives vascular morphogenesis in the mouse retina
    2
    1. scibot 11 Oct 2022
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      DOI: 10.1016/j.devcel.2022.09.002

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    sciencedirect.com/science/article/pii/S1534580722006323
  44. Mar 2022
  45. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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    1. scibot 11 Mar 2022
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      DOI: 10.7554/eLife.73150

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    elifesciences.org/articles/73150
  46. Feb 2022
  47. www.sciencedirect.com www.sciencedirect.com
    Contribution of ferroptosis and GPX4’s dual functions to osteoarthritis progression
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    1. scibot 11 Feb 2022
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      DOI: 10.1016/j.ebiom.2022.103847

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      DOI: 10.1016/j.ebiom.2022.103847

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    sciencedirect.com/science/article/pii/S2352396422000317
  48. www.sciencedirect.com www.sciencedirect.com
    Upregulation of CD14 in mesenchymal stromal cells accelerates lipopolysaccharide-induced response and enhances antibacterial properties
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      DOI: 10.1016/j.isci.2022.103759

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    sciencedirect.com/science/article/pii/S2589004222000293
  49. Jan 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Sphingosine 1-phosphate receptor 4 promotes nonalcoholic steatohepatitis by activating NLRP3 inflammasome
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    1. scibot 12 Jan 2022
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      DOI: 10.1016/j.jcmgh.2021.12.002

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    sciencedirect.com/science/article/pii/S2352345X21002526
  51. Dec 2021
  52. www.nature.com www.nature.com
    A targetable LIFR−NF-κB−LCN2 axis controls liver tumorigenesis and vulnerability to ferroptosis
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    1. scibot 21 Dec 2021
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      DOI: 10.1038/s41467-021-27452-9

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    nature.com/articles/s41467-021-27452-9
  53. elifesciences.org elifesciences.org
    Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis
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      DOI: 10.7554/eLife.68487

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    elifesciences.org/articles/68487
  54. Nov 2021
  55. www.sciencedirect.com www.sciencedirect.com
    m6A mRNA methylation-directed myeloid cell activation controls progression of NAFLD and obesity
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    sciencedirect.com/science/article/pii/S2211124721014479
  56. link.springer.com link.springer.com
    Carbon dioxide inhibits COVID-19-type proinflammatory responses through extracellular signal-regulated kinases 1 and 2, novel carbon dioxide sensors
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      DOI: 10.1007/s00018-021-04005-3

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    link.springer.com/article/10.1007/s00018-021-04005-3
  57. Oct 2021
  58. www.embopress.org www.embopress.org
    Promyelocytic leukemia protein targets MK2 to promote cytotoxicity
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      DOI: 10.15252/embr.202052254

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    embopress.org/doi/full/10.15252/embr.202052254
  59. Sep 2021
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STING nuclear partners contribute to innate immune signaling responses
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      DOI: 10.1016/j.isci.2021.103055

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    ncbi.nlm.nih.gov/pmc/articles/PMC8436130/
  61. Aug 2021
  62. academic.oup.com academic.oup.com
    Small Heterodimer Partner Regulates Dichotomous T Cell Expansion by Macrophages
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      DOI: 10.1210/en.2019-00025

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    academic.oup.com/endo/article/160/7/1573/5482546
  63. www.sciencedirect.com www.sciencedirect.com
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      DOI: 10.1016/j.molcel.2018.10.034

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    sciencedirect.com/science/article/pii/S1097276518308943
  64. www.ncbi.nlm.nih.govhttp: www.ncbi.nlm.nih.govhttp:
    Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage
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      DOI: 10.1016/j.molcel.2018.07.034

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    ncbi.nlm.nih.govhttp://europepmc.org/articles/PMC6127031/
  65. Jul 2021
  66. journals.sagepub.com journals.sagepub.com
    ANGPTL2 Promotes Inflammation via Integrin α5β1 in Chondrocytes - Mami Takano, Naoto Hirose, Chikako Sumi, Makoto Yanoshita, Sayuri Nishiyama, Azusa Onishi, Yuki Asakawa, Kotaro Tanimoto,
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    1. scibot 30 Jul 2021
      anti–total NF-κB p65

      DOI: 10.1177/1947603519878242

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    journals.sagepub.com/doi/full/10.1177/1947603519878242
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.molcel.2018.07.034

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  68. www.jneurosci.org www.jneurosci.org
    Reduction of Ether-Type Glycerophospholipids, Plasmalogens, by NF-κB Signal Leading to Microglial Activation
    2
    1. scibot 28 Jul 2021
      AB_10828935

      DOI: 10.1523/JNEUROSCI.3941-15.2017

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      AB_10828935

      DOI: 10.1523/JNEUROSCI.3941-15.2017

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    jneurosci.org/content/37/15/4074
  69. Jun 2021
  70. www.hindawi.com www.hindawi.com
    HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1-/- Mice
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      RRID:AB_10828935

      DOI: 10.1155/2021/6620873

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  71. May 2021
  72. www.sciencedirect.com www.sciencedirect.com
    SPARC regulation of PMN clearance protects from pristane-induced lupus and rheumatoid arthritis
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      RRID:AB_10828935

      DOI: 10.1016/j.isci.2021.102510

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    sciencedirect.com/science/article/pii/S2589004221004788
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Pharmacological Effect and Mechanism of Lanthanum Hydroxide on Vascular Calcification Caused by Chronic Renal Failure Hyperphosphatemia
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    1. scibot 01 May 2021
      RRID:AB_10828935

      DOI: 10.3389/fcell.2021.639127

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  74. Mar 2021
  75. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 29 Mar 2021
      RRID:AB_10828935

      DOI: 10.1111/bph.15396

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15396
  76. www.sciencedirect.com www.sciencedirect.com
    TNF-α and α-synuclein fibrils differently regulate human astrocyte immune reactivity and impair mitochondrial respiration
    1
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      RRID:AB_10828935

      DOI: 10.1016/j.celrep.2021.108895

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    sciencedirect.com/science/article/pii/S2211124721002096
  77. academic.oup.com academic.oup.com
    CXCR4 signaling at the fetal-maternal interface may drive inflammation and syncytia formation during ovine pregnancy †
    1
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      AB_10828935

      DOI: 10.1093/biolre/ioaa203

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    academic.oup.com/biolreprod/article/104/2/468/5952668
  78. Sep 2020
  79. www.sciencedirect.com www.sciencedirect.com
    Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration
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      DOI: 10.1016/j.celrep.2020.107796

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  80. www.sciencedirect.com www.sciencedirect.com
    CD28 Regulates Metabolic Fitness for Long-Lived Plasma Cell Survival
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      DOI: 10.1016/j.celrep.2020.107815

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  81. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    In utero inflammatory challenge induces an early activation of the hepatic innate immune response in late gestation fetal sheep - Miguel A Zarate, Stephanie R Wesolowski, Leanna M Nguyen, Robyn K De Dios, Randall B Wilkening, Paul J Rozance, Clyde J Wright,
    2
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      RRID:AB_10828935

      DOI: 10.1177/1753425920928388

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    2. scibot 12 Sep 2020
      RRID:AB_10828935

      DOI: 10.1177/1753425920928388

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  82. Jan 2020
  83. onlinelibrary.wiley.com onlinelibrary.wiley.com
    TAK1 inhibition in mouse astrocyte cultures ameliorates cytokine‐induced chemokine production and neutrophil migration
    1
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      RRID:AB_10828935

      DOI: 10.1111/jnc.14930

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14930
  84. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 13 Jan 2020
      RRID:AB_10828935

      DOI: 10.1111/bph.14713

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  85. www.sciencedirect.com www.sciencedirect.com
    Interleukin-1β Induces mtDNA Release to Activate Innate Immune Signaling via cGAS-STING
    1
    1. scibot 12 Jan 2020
      RRID:AB_10828935

      DOI: 10.1016/j.molcel.2019.02.038

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    sciencedirect.com/science/article/pii/S1097276519301492
  86. Nov 2018
  87. www.ncbi.nlm.nih.govhttp: www.ncbi.nlm.nih.govhttp:
    Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage
    1
    1. scibot 05 Nov 2018
      RRID:AB_10828935

      Curator: @evieth

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    ncbi.nlm.nih.govhttp://europepmc.org/articles/PMC6127031/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reversal of angiotensin ll-induced β-cell dedifferentiation via inhibition of NF-κb signaling
    1
    1. scibot 05 Nov 2018
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    ncbi.nlm.nih.gov/pmc/articles/PMC6092859/
  89. molmed.biomedcentral.com molmed.biomedcentral.com
    Untitled document
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    molmed.biomedcentral.com/articles/10.1186/s10020-018-0044-3
  90. Nov 2017
  91. www.sciencedirect.com www.sciencedirect.com
    Divergent JNK Phosphorylation of HDAC3 in Triple-Negative Breast Cancer Cells Determines HDAC Inhibitor Binding and Selectivity
    1
    1. scibot 08 Nov 2017
      6956P

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S2451945617303136
  92. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Protein kinase D exerts neuroprotective functions during oxidative stress via Nuclear Factor kappaB‐independent signaling pathways
    1
    1. scibot 08 Nov 2017
      AB_10828935

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14131/full