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Dec 2025
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Degradation of LMO2 in T cell leukaemia results in collateral breakdown of transcription complex partners and causes LMO2-dependent apoptosis

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Cellular and immune adaptations at the maternal-fetal interface in bats

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Dual role of Oct4 and Sox2 in controlling the developmental capacity and timing of tissue morphogenesis in the embryonic lineage

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Nov 2025
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2025.11.18.688276v1.full-html.html

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Sep 2025
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Combinatorial BMP4 and activin direct the choice between alternate routes to endoderm in a stem cell model of human gastrulation

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May 2025
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Transcription factor cooperativity at a GATA3 tandem DNA sequence determines oncogenic enhancer-mediated activation

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Post-gastrulation amnioids as a stem cell-derived model of human extra-embryonic development

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Apr 2025
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Derivation of human trophoblast stem cells from placentas at birth

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Mar 2025
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The HAVCR1-centric host factor network drives Zika virus vertical transmission

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Self-organization of mouse embryonic stem cells into reproducible pre-gastrulation embryo models via CRISPRa programming

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Derivation of human trophoblast stem cells from placentas at birth

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Development of apical out trophoblast stem cell derived organoids to model early human pregnancy

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Sep 2024
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Marmoset and human trophoblast stem cells differ in signaling requirements and recapitulate divergent modes of trophoblast invasion

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Aug 2024
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FRA1 controls acinar cell plasticity during murine KrasG12D-induced pancreatic acinar to ductal metaplasia

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Jul 2024
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The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening

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cell.com/cell-metabolism/fulltext/S1550-4131(24)00231-6
Jun 2024
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Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells

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Apr 2024
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Oct4 controls basement membrane development during human embryogenesis

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Harnessing developmental dynamics of spinal cord extracellular matrix improves regenerative potential of spinal cord organoids

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Jan 2024
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Selective induction of human renal interstitial progenitor-like cell lineages from iPSCs reveals development of mesangial and EPO-producing cells

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Metabolic switch regulates lineage plasticity and induces synthetic lethality in triple-negative breast cancer

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Elimination of oncogenic KRAS in genetic mouse models eradicates pancreatic cancer by inducing FAS-dependent apoptosis by CD8+ T cells

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Dec 2023
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Human iPSC-derived renal collecting duct organoid model cystogenesis in ADPKD

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Nov 2023
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Highly-parallel production of designer organoids by mosaic patterning of progenitors

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  DOI: 10.1101/2023.10.25.564017
  
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Sep 2023
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3D-cultured blastoids model human embryogenesis from pre-implantation to early gastrulation stages

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Jun 2023
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Spatially resolved multi-omics single-cell analyses inform mechanisms of immune-dysfunction in pancreatic cancer

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Neuroprotective protein ADNP-dependent histone remodeling complex promotes T helper 2 immune cell differentiation

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May 2023
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Efficient self-organization of blastoids solely from mouse ESCs is facilitated by transient reactivation of 2C gene network

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Neurulation of the cynomolgus monkey embryo achieved from 3D blastocyst culture

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Establishment of bovine trophoblast stem cells

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Apr 2023
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Integrative dissection of gene regulatory elements at base resolution

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  DOI: 10.1016/j.xgen.2023.100318
  
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A genome-wide CRISPR screen maps endogenous regulators of PPARG gene expression in bladder cancer

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Mar 2023
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Polarity inversion reorganizes the stem cell compartment of the trophoblast lineage

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Nov 2022
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Protocol to isolate mature thymic T cell subsets using fluorescence-activated cell sorting for assessing gene expression by RNA-seq and transcription factor binding across the genome by CUT&RUN

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  DOI: 10.1016/j.xpro.2022.101839
  
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sciencedirect.com/science/article/pii/S2666166722007195
Sep 2022
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Single-cell analysis of embryoids reveals lineage diversification roadmaps of early human development

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Aug 2022
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Single-cell and spatial mapping Identify cell types and signaling Networks in the human ureter

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  DOI: 10.1016/j.devcel.2022.07.004
  
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Jun 2022
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Protocol for the generation and expansion of human iPS cell-derived ureteric bud organoids

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  DOI: 10.1016/j.xpro.2022.101484
  
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Oncogenic Vav1-Myo1f induces therapeutically targetable macrophage-rich tumor microenvironment in peripheral T cell lymphoma

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  DOI: 10.1016/j.celrep.2022.110695
  
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Mar 2022
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dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region

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  DOI: 10.1016/j.celrep.2022.110457
  
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Sep 2021
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TGFβ signalling is required to maintain pluripotency of human naïve pluripotent stem cells

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  DOI: 10.7554/eLife.67259
  
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Mar 2021
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Systematic characterization of mutations altering protein degradation in human cancers

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  DOI: 10.1016/j.molcel.2021.01.020
  
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GATA transcription factors, SOX17 and TFAP2C, drive the human germ-cell specification program

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  DOI: 10.26508/lsa.202000974
  
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Feb 2021
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Two distinct trophectoderm lineage stem cells from human pluripotent stem cells

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  DOI: 10.1016/j.jbc.2021.100386
  
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Dec 2020
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High-resolution transcriptional and morphogenetic profiling of cells from micropatterned human ESC gastruloid cultures

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  DOI: 10.7554/eLife.59445
  
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Sep 2020
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A Modular Differentiation System Maps Multiple Human Kidney Lineages from Pluripotent Stem Cells

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  DOI: 10.1016/j.celrep.2020.03.040
  
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Gata3-controlled nucleosome eviction drives Myc enhancer activity in T-cell development and leukemia

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  DOI: 10.1158/2159-8290.CD-19-0471
  
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GATA3 Mediates a Fast, Irreversible Commitment to BMP4-Driven Differentiation in Human Embryonic Stem Cells

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  DOI: 10.1016/j.stem.2020.03.005
  
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Expansion of Human iPSC-Derived Ureteric Bud Organoids with Repeated Branching Potential

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  DOI: 10.1016/j.celrep.2020.107963
  
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Aug 2020
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Evolution of the immune landscape during progression of pancreatic intraductal papillary mucinous neoplasms to invasive cancer

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Jan 2020
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Liver-Type Glutaminase GLS2 Is a Druggable Metabolic Node in Luminal-Subtype Breast Cancer

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  DOI: 10.1016/j.celrep.2019.08.076
  
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A CHAF1B-Dependent Molecular Switch in Hematopoiesis and Leukemia Pathogenesis

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  DOI: 10.1016/j.ccell.2018.10.004
  
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Nov 2018
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Derivation of Human Trophoblast Stem Cells

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Genomic Subtypes of Non-invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency

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