39 Matching Annotations
  1. Jun 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting TMED4 enhances CD8+ T cell function and CAR T cell efficacy in solid tumors through the IRE1α-autophagy axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13262630/
  3. www.science.org www.science.org
    Targeting TMED4 enhances CD8+ T cell function and CAR T cell efficacy in solid tumors through the IRE1α-autophagy axis
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    science.org/doi/10.1126/sciadv.aee0517
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Overcoming ADC resistance in advanced colorectal cancer by dual targeting of TROP2 and PERK to suppress Wnt/β-catenin signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13198297/
  5. May 2026
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TENT5A Maintains MYC mRNA Stability to Enhance Osteosarcoma Stemness
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    pmc.ncbi.nlm.nih.gov/articles/PMC13136882/
  7. Mar 2026
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct signaling mechanisms and proteome phenotypes are elicited by compartment-specific genetic defects of copper homeostasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12871135/
  9. www.sciencedirect.com www.sciencedirect.com
    R-propranolol Promotes the Adipogenesis and Subsequent Apoptosis of Hemangioma Stem Cells through the PERK Signaling Pathway
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    sciencedirect.com/science/article/pii/S0002944026000659
  10. Feb 2026
  11. www.sciencedirect.com www.sciencedirect.com
    Triglycerides induce endoplasmic reticulum lipid bilayer stress to activate PERK and enhance antifungal immunity
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    sciencedirect.com/science/article/pii/S2211124726000549
  12. Nov 2025
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of Histone Deacetylases Induces Cancer Cell Apoptosis Through the PERK Pathway of ER Stress Response
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    pmc.ncbi.nlm.nih.gov/articles/PMC12571189/
  14. Oct 2025
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PERK-dependent reciprocal crosstalk between ER and non-centrosomal microtubules coordinates ER architecture and cell shape
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    pmc.ncbi.nlm.nih.gov/articles/PMC12548782/
  16. May 2025
  17. www.sciencedirect.com www.sciencedirect.com
    Selective removal of astrocytic PERK protects against glymphatic impairment and decreases toxic aggregation of β-amyloid and tau
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    sciencedirect.com/science/article/pii/S0896627325003101
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration | Molecular Biology of the Cell
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    pmc.ncbi.nlm.nih.gov/articles/PMC11974963/
  19. Jan 2025
  20. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11866496/
  21. Dec 2024
  22. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IFRD1 is required for maintenance of bladder epithelial homeostasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11613175/
  23. Oct 2024
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adaptive protein synthesis in genetic models of copper deficiency and childhood neurodegeneration
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    ncbi.nlm.nih.gov/pmc/articles/PMC11419079/
  25. Jun 2024
  26. www.sciencedirect.com www.sciencedirect.com
    The HRD1-SEL1L ubiquitin ligase regulates stress granule homeostasis in couple with distinctive signaling branches of ER stress
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    sciencedirect.com/science/article/pii/S2589004224014214
  27. May 2024
  28. www.sciencedirect.com www.sciencedirect.com
    Insights from multi-omic modeling of neurodegeneration in xeroderma pigmentosum using an induced pluripotent stem cell system
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    sciencedirect.com/science/article/pii/S2211124724005710
  29. 52.53.155.43 52.53.155.43
    Targeting eIF2α in TBI-induced traumatic optic neuropathy: Effects of Salubrinal and the Integrated Stress Response Inhibitor
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    52.53.155.43/e49e13012caa173776051da0a73c8b285e75644e/2024.02.15.580435v1.full-html.html
  30. www.sciencedirect.com www.sciencedirect.com
    Obesity disrupts the pituitary-hepatic UPR communication leading to NAFLD progression
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    sciencedirect.com/science/article/pii/S1550413124001347
  31. Apr 2024
  32. www.sciencedirect.com www.sciencedirect.com
    Cancer SLC6A6-mediated taurine uptake transactivates immune checkpoint genes and induces exhaustion in CD8+ T cells
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    sciencedirect.com/science/article/pii/S0092867424003039
  33. Jun 2023
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Brief Oxygen Exposure after Traumatic Brain Injury Hastens Recovery and Promotes Adaptive Chronic Endoplasmic Reticulum Stress Responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10298247/
  35. May 2023
  36. www.sciencedirect.com www.sciencedirect.com
    Activation of endoplasmic reticulum stress in premature aging via the inner nuclear membrane protein SUN2
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    sciencedirect.com/science/article/pii/S2211124723005454
  37. academic.oup.com academic.oup.com
    Berberine ameliorates obesity by inducing GDF15 secretion by brown adipocytes
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    academic.oup.com/endo/article/164/4/bqad035/7056674
  38. www.sciencedirect.com www.sciencedirect.com
    Allosteric HSP70 inhibitors perturb mitochondrial proteostasis and overcome proteasome inhibitor resistance in multiple myeloma
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    sciencedirect.com/science/article/pii/S2451945622002422
  39. Dec 2022
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9719099/
  41. Sep 2022
  42. www.sciencedirect.com www.sciencedirect.com
    De novo sphingolipid biosynthesis necessitates detoxification in cancer cells
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    sciencedirect.com/science/article/pii/S2211124722012566
  43. May 2022
  44. www.sciencedirect.com www.sciencedirect.com
    Lipogenesis mediated by OGR1 regulates metabolic adaptation to acid stress in cancer cells via autophagy
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    sciencedirect.com/science/article/pii/S2211124722005630
  45. Mar 2022
  46. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    TIMP2 mediates endoplasmic reticulum stress contributing to sepsis-induced acute kidney injury
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202101555RR
  47. Nov 2021
  48. academic.oup.com academic.oup.com
    TXNIP links anticipatory unfolded protein response to estrogen reprogramming glucose metabolism in breast cancer cells
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    academic.oup.com/endo/article/163/1/bqab212/6382455
  49. www.sciencedirect.com www.sciencedirect.com
    ADH5-mediated NO bioactivity maintains metabolic homeostasis in brown adipose tissue
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    sciencedirect.com/science/article/pii/S2211124721014819
  50. Aug 2021
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Notch-induced endoplasmic reticulum-associated degradation governs mouse thymocyte β−selection
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    ncbi.nlm.nih.gov/pmc/articles/PMC8315795/
  52. academic.oup.com academic.oup.com
    Untitled document
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    academic.oup.com/endo/article/158/10/3162/4083504
  53. Sep 2020
  54. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Astroglial biotin deprivation under endoplasmic reticulum stress uncouples BCAA‐mTORC1 role in lipid synthesis to prolong autophagy inhibition in the aging brain
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14979
  55. www.sciencedirect.com www.sciencedirect.com
    Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells
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    sciencedirect.com/science/article/pii/S2211124720308755
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Melanoblast transcriptome analysis reveals pathways promoting melanoma metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC6965108/
  57. Jan 2020
  58. www.frontiersin.org www.frontiersin.org
    Upregulated Expression of MicroRNA-204-5p Leads to the Death of Dopaminergic Cells by Targeting DYRK1A-Mediated Apoptotic Signaling Cascade
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    frontiersin.org/article/10.3389/fncel.2019.00399/full
  59. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.14713
  60. Nov 2018
  61. www.sciencedirect.com www.sciencedirect.com
    Epidithiodiketopiperazines Inhibit Protein Degradation by Targeting Proteasome Deubiquitinase Rpn11
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    sciencedirect.com/science/article/pii/S2451945618302642
  62. www.jneurosci.org www.jneurosci.org
    JIP1-Mediated JNK Activation Negatively Regulates Synaptic Plasticity and Spatial Memory
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    jneurosci.org/content/38/15/3708
  63. Nov 2017
  64. academic.oup.com academic.oup.com
    Angiotensin II Causes β-Cell Dysfunction Through an ER Stress-Induced Proinflammatory Response
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    academic.oup.com/endo/article/158/10/3162/4083504/Angiotensin-II-Causes-Cell-Dysfunction-Through-an