52 Matching Annotations
  1. Jun 2024
  2. www.sciencedirect.com www.sciencedirect.com
    The phosphorylation-deubiquitination positive feedback loop of the CHK2-USP7 axis stabilizes p53 under oxidative stress
    1
    1. scibot 21 Jun 2024
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    sciencedirect.com/science/article/pii/S2211124724006946
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    The HRD1-SEL1L ubiquitin ligase regulates stress granule homeostasis in couple with distinctive signaling branches of ER stress
    1
    1. scibot 21 Jun 2024
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      DOI: 10.1016/j.isci.2024.110196

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    sciencedirect.com/science/article/pii/S2589004224014214
  4. May 2024
  5. www.science.org www.science.org
    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
    1
    1. scibot 09 May 2024
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      DOI: 10.1126/sciadv.adl6082

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    science.org/doi/10.1126/sciadv.adl6082
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    Ubiquitin-mediated regulation of APE2 protein abundance
    1
    1. scibot 07 May 2024
      Cell Signaling Technology #8081

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    sciencedirect.com/science/article/pii/S0021925824018386
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p37 regulates VCP/p97 shuttling and functions in the nucleus and cytosol
    1
    1. scibot 05 May 2024
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      DOI: 10.1126/sciadv.adl6082

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    ncbi.nlm.nih.gov/pmc/articles/PMC11068011/
  8. Apr 2024
  9. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
    1
    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114163

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    sciencedirect.com/science/article/pii/S2211124724004911
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    ER-associated degradation adapter Sel1L is required for CD8+ T cell function and memory formation following acute viral infection
    1
    1. scibot 30 Apr 2024
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      DOI: 10.1016/j.celrep.2024.114156

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    sciencedirect.com/science/article/pii/S2211124724004844
  11. Mar 2024
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The acetylase activity of Cdu1 regulates bacterial exit from infected cells by protecting Chlamydia effectors from degradation
    1
    1. scibot 19 Mar 2024
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      DOI: 10.7554/eLife.87386

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    ncbi.nlm.nih.gov/pmc/articles/PMC10942603/
  13. www.sciencedirect.com www.sciencedirect.com
    Aging-induced tRNAGlu-derived fragment impairs glutamate biosynthesis by targeting mitochondrial translation-dependent cristae organization
    2
    1. scibot 08 Mar 2024
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      DOI: 10.1016/j.cmet.2024.02.011

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    2. scibot 08 Mar 2024
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      DOI: 10.1016/j.cmet.2024.02.011

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    sciencedirect.com/science/article/pii/S1550413124000573
  14. Feb 2024
  15. www.sciencedirect.com www.sciencedirect.com
    The GATOR2 complex maintains lysosomal-autophagic function by inhibiting the protein degradation of MiT/TFEs
    1
    1. scibot 08 Feb 2024
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      DOI: 10.1016/j.molcel.2024.01.012

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    sciencedirect.com/science/article/pii/S1097276524000480
  16. Dec 2023
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62
    1
    1. scibot 22 Dec 2023
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      DOI: 10.1038/s41467-023-44033-0

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    ncbi.nlm.nih.gov/pmc/articles/PMC10730909/
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    De novo NAD+ synthesis contributes to CD8+ T cell metabolic fitness and antitumor function
    1
    1. scibot 21 Dec 2023
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      DOI: 10.1016/j.celrep.2023.113518

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    sciencedirect.com/science/article/pii/S2211124723015309
  19. Nov 2023
  20. www.sciencedirect.com www.sciencedirect.com
    RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks
    1
    1. scibot 28 Nov 2023
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      DOI: 10.1016/j.molcel.2023.10.012

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    sciencedirect.com/science/article/pii/S1097276523008493
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    FBXO38 mediates FGL1 ubiquitination and degradation to enhance cancer immunity and suppress inflammation
    1
    1. scibot 17 Nov 2023
      RRID:AB_10859893

      DOI: 10.1016/j.celrep.2023.113362

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    sciencedirect.com/science/article/pii/S2211124723013748
  22. Oct 2023
  23. link.springer.com link.springer.com
    MLKL regulates Cx43 ubiquitinational degradation and mediates neuronal necroptosis in ipsilateral thalamus after focal cortical infarction
    1
    1. scibot 31 Oct 2023
      RRID:AB_10859893

      DOI: 10.1186/s13041-023-01064-4

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    link.springer.com/article/10.1186/s13041-023-01064-4
  24. www.sciencedirect.com www.sciencedirect.com
    PAICS ubiquitination recruits UBAP2 to trigger phase separation for purinosome assembly
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    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.molcel.2023.09.028

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    sciencedirect.com/science/article/pii/S1097276523007554
  25. Sep 2023
  26. www.sciencedirect.com www.sciencedirect.com
    TMEM127 suppresses tumor development by promoting RET ubiquitination, positioning, and degradation
    1
    1. scibot 07 Sep 2023
      RRID:AB_10859893

      DOI: 10.1016/j.celrep.2023.113070

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    sciencedirect.com/science/article/pii/S2211124723010811
  27. Aug 2023
  28. www.sciencedirect.com www.sciencedirect.com
    Molecular mechanism for activation of the 26S proteasome by ZFAND5
    1
    1. scibot 18 Aug 2023
      RRID:AB_10859893

      DOI: 10.1016/j.molcel.2023.07.023

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    sciencedirect.com/science/article/abs/pii/S109727652300566X
  29. Jul 2023
  30. 52.53.155.43 52.53.155.43
    NEMO reshapes the protein aggregate interface and promotes aggrephagy by co-condensation with p62
    1
    1. scibot 19 Jul 2023
      RRID:AB_10859893

      DOI: 10.1101/2023.06.05.543428

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    52.53.155.43/5185b06857919afc7fae38712332798a8a903a3a/2023.06.05.543428v1.full-html.html
  31. Jun 2023
  32. www.sciencedirect.com www.sciencedirect.com
    UBE2M-mediated neddylation of TRIM21 regulates obesity-induced inflammation and metabolic disorders
    1
    1. scibot 21 Jun 2023
      RRID:AB_10859893

      DOI: 10.1016/j.cmet.2023.05.011

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    sciencedirect.com/science/article/pii/S1550413123002097
  33. May 2023
  34. www.nature.com www.nature.com
    Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
    1
    1. scibot 05 May 2023
      RRID:AB_10859893

      DOI: 10.1038/s41467-022-31905-0

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    nature.com/articles/s41467-022-31905-0
  35. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells
    1
    1. scibot 05 May 2023
      RRID:AB_10859893

      DOI: 10.1002/cac2.12332

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    onlinelibrary.wiley.com/doi/10.1002/cac2.12332
  36. Apr 2023
  37. www.sciencedirect.com www.sciencedirect.com
    PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
    1
    1. scibot 08 Apr 2023
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      DOI: 10.1016/j.celrep.2023.112340

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    sciencedirect.com/science/article/pii/S2211124723003510
  38. Feb 2023
  39. www.sciencedirect.com www.sciencedirect.com
    TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away
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    1. scibot 23 Feb 2023
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      DOI: 10.1016/j.celrep.2023.112125

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      DOI: 10.1016/j.celrep.2023.112125

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    sciencedirect.com/science/article/pii/S2211124723001365
  40. www.sciencedirect.com www.sciencedirect.com
    RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex
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    1. scibot 17 Feb 2023
      RRID:AB_10859893

      DOI: 10.1016/j.celrep.2023.112097

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    sciencedirect.com/science/article/pii/S2211124723001080
  41. Jan 2023
  42. www.sciencedirect.com www.sciencedirect.com
    Type I interferon/STAT1 signaling regulates UBE2M-mediated antiviral innate immunity in a negative feedback manner
    1
    1. scibot 21 Jan 2023
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      DOI: 10.1016/j.celrep.2023.112002

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    sciencedirect.com/science/article/pii/S221112472300013X
  43. Dec 2022
  44. www.sciencedirect.com www.sciencedirect.com
    Excessive proteostasis contributes to pathology in fragile X syndrome
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    1. scibot 11 Dec 2022
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      DOI: 10.1016/j.neuron.2022.11.012

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    sciencedirect.com/science/article/pii/S0896627322010352
  45. Nov 2022
  46. www.embopress.org www.embopress.org
    LUBAC assembles a ubiquitin signaling platform at mitochondria for signal amplification and transport of NF-κB to the nucleus
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    1. scibot 19 Nov 2022
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      DOI: 10.15252/embj.2022112006

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    embopress.org/doi/10.15252/embj.2022112006
  47. Jul 2022
  48. www.nature.com www.nature.com
    Deubiquitinase OTUD6A promotes breast cancer progression by increasing TopBP1 stability and rendering tumor cells resistant to DNA-damaging therapy
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      DOI: 10.1038/s41418-022-01036-6

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    nature.com/articles/s41418-022-01036-6
  49. Mar 2022
  50. www.sciencedirect.com www.sciencedirect.com
    Delicate regulation of IL-1β-mediated inflammation by cyclophilin A
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    1. scibot 16 Mar 2022
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      DOI: 10.1016/j.celrep.2022.110513

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    sciencedirect.com/science/article/pii/S2211124722002492
  51. elifesciences.org elifesciences.org
    Confined migration promotes cancer metastasis through resistance to anoikis and increased invasiveness
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    1. scibot 11 Mar 2022
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      DOI: 10.7554/eLife.73150

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    elifesciences.org/articles/73150
  52. www.sciencedirect.com www.sciencedirect.com
    K48/K63-linked polyubiquitination of ATG9A by TRAF6 E3 ligase regulates oxidative stress-induced autophagy
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    1. scibot 04 Mar 2022
      Cell Signaling Tehnology cat# 8081

      DOI: 10.1016/j.celrep.2022.110354

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    sciencedirect.com/science/article/pii/S2211124722000705
  53. Feb 2022
  54. www.sciencedirect.com www.sciencedirect.com
    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
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      DOI: 10.1016/j.molcel.2022.01.022

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    sciencedirect.com/science/article/pii/S1097276522000879
  55. Dec 2021
  56. www.sciencedirect.com www.sciencedirect.com
    Translocation of polyubiquitinated protein substrates by the hexameric Cdc48 ATPase
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    1. scibot 28 Dec 2021
      8081S

      DOI: 10.1016/j.molcel.2021.11.033

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    sciencedirect.com/science/article/pii/S1097276521010352
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation
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      DOI: 10.3389/fphys.2021.779547

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    ncbi.nlm.nih.gov/pmc/articles/PMC8669767/
  58. Aug 2021
  59. www.sciencedirect.com www.sciencedirect.com
    Feedback repression of PPARα signaling by Let-7 microRNA
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    1. scibot 15 Aug 2021
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      DOI: 10.1016/j.celrep.2021.109506

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    sciencedirect.com/science/article/pii/S2211124721009360
  60. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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      DOI: 10.1016/j.celrep.2019.02.067

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    sciencedirect.com/science/article/pii/S2211124719302463
  61. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAc Transferase Links Glucose Metabolism to MAVS-Mediated Antiviral Innate Immunity
    1
    1. scibot 02 Aug 2021
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      DOI: 10.1016/j.chom.2018.11.001

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    sciencedirect.com/science/article/pii/S1931312818305584
  62. Jun 2021
  63. www.cell.com www.cell.com
    Arginine monomethylation by PRMT7 controls MAVS-mediated antiviral innate immunity
    1
    1. scibot 25 Jun 2021
      RRID:AB_10859893

      DOI: 10.1016/j.molcel.2021.06.004

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00451-2
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    Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation
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    1. scibot 23 Jun 2021
      RRID:AB_10859893

      DOI: 10.1016/j.celrep.2021.109272

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    sciencedirect.com/science/article/pii/S2211124721006392
  65. May 2021
  66. www.sciencedirect.com www.sciencedirect.com
    Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation
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    1. scibot 07 May 2021
      RRID:AB_10859893

      DOI: 10.1016/j.molcel.2020.10.017

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    sciencedirect.com/science/article/pii/S1097276520307243
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    A class of viral inducer of degradation of the necroptosis adaptor RIPK3 regulates virus-induced inflammation
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    1. scibot 07 May 2021
      RRID:AB_10859893

      DOI: 10.1016/j.immuni.2020.11.020

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    sciencedirect.com/science/article/pii/S1074761320305070
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    Proteasome stress in skeletal muscle mounts a long-range protective response that delays retinal and brain aging
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    1. scibot 01 May 2021
      RRID:AB_10859893

      DOI: 10.1016/j.cmet.2021.03.005

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    sciencedirect.com/science/article/pii/S1550413121001121
  69. Nov 2020
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of ubiquitin Ser57 kinases regulating the oxidative stress response in yeast
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    1. scibot 12 Nov 2020
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      DOI: 10.7554/eLife.58155

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    ncbi.nlm.nih.gov/pmc/articles/PMC7647399/
  71. Sep 2020
  72. www.sciencedirect.com www.sciencedirect.com
    Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer
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    1. scibot 17 Sep 2020
      RRID:AB_10859893

      DOI: 10.1016/j.celrep.2020.107745

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    sciencedirect.com/science/article/pii/S2211124720307257
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    Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer
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    1. scibot 11 Sep 2020
      RRID:AB_10859893

      DOI: 10.1016/j.ccell.2020.02.003

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    sciencedirect.com/science/article/pii/S1535610820300921
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    Shifts in Ribosome Engagement Impact Key Gene Sets in Neurodevelopment and Ubiquitination in Rett Syndrome
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    1. scibot 03 Sep 2020
      RRID:AB_10859893

      DOI: 10.1016/j.celrep.2020.02.107

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    sciencedirect.com/science/article/pii/S2211124720302886
  75. Jan 2020
  76. www.sciencedirect.com www.sciencedirect.com
    Targeting Degradation of the Transcription Factor C/EBPβ Reduces Lung Fibrosis by Restoring Activity of the Ubiquitin-Editing Enzyme A20 in Macrophages
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    1. scibot 13 Jan 2020
      RRID:AB_10859893

      DOI: 10.1016/j.immuni.2019.06.014

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    sciencedirect.com/science/article/pii/S1074761319302845
  77. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:AB_10859893

      DOI: 10.1016/j.celrep.2019.01.072

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    sciencedirect.com/science/article/pii/S2211124719301019
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    Iruka Eliminates Dysfunctional Argonaute by Selective Ubiquitination of Its Empty State
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    1. scibot 12 Jan 2020
      RRID:AB_10859893

      DOI: 10.1016/j.molcel.2018.10.033

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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276518308931